HK1245099A1 - 改善认知功能的方法和组合物 - Google Patents
改善认知功能的方法和组合物 Download PDFInfo
- Publication number
- HK1245099A1 HK1245099A1 HK18104537.2A HK18104537A HK1245099A1 HK 1245099 A1 HK1245099 A1 HK 1245099A1 HK 18104537 A HK18104537 A HK 18104537A HK 1245099 A1 HK1245099 A1 HK 1245099A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- group
- oxo
- methyl
- hydrogen
- alkyl
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10584708P | 2008-10-16 | 2008-10-16 | |
| US61/105,847 | 2008-10-16 | ||
| US15263109P | 2009-02-13 | 2009-02-13 | |
| US61/152,631 | 2009-02-13 | ||
| US17553609P | 2009-05-05 | 2009-05-05 | |
| US61/175,536 | 2009-05-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1245099A1 true HK1245099A1 (zh) | 2018-08-24 |
Family
ID=41403972
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK18104537.2A HK1245099A1 (zh) | 2008-10-16 | 2018-04-06 | 改善认知功能的方法和组合物 |
Country Status (12)
| Country | Link |
|---|---|
| US (5) | US20100099735A1 (OSRAM) |
| EP (2) | EP3260118B1 (OSRAM) |
| JP (3) | JP5917148B2 (OSRAM) |
| CN (2) | CN107243007A (OSRAM) |
| AU (1) | AU2009303834B2 (OSRAM) |
| BR (1) | BRPI0920342A2 (OSRAM) |
| CA (1) | CA2740610C (OSRAM) |
| DK (2) | DK3260118T3 (OSRAM) |
| EA (1) | EA033130B1 (OSRAM) |
| ES (2) | ES2865504T3 (OSRAM) |
| HK (1) | HK1245099A1 (OSRAM) |
| WO (1) | WO2010044878A1 (OSRAM) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2865504T3 (es) | 2008-10-16 | 2021-10-15 | Univ Johns Hopkins | Procedimientos y composiciones para la mejora de la función cognitiva |
| EP3400934A1 (en) * | 2011-02-09 | 2018-11-14 | The Johns Hopkins University | Levetiracetam for improving cognitive function |
| EP2919788A4 (en) | 2012-11-14 | 2016-05-25 | Univ Johns Hopkins | METHOD AND COMPOSITIONS FOR TREATING SCHIZOPHRENIA |
| EP3827820A1 (en) | 2013-03-15 | 2021-06-02 | The Johns Hopkins University | Brivaracetam for improving cognitive function |
| US20160030391A1 (en) * | 2013-03-15 | 2016-02-04 | The Johns Hopkins University | Methods and compositions for improving cognitive function |
| WO2014144801A1 (en) | 2013-03-15 | 2014-09-18 | Agenebio Inc. | Methods and compositions for improving cognitive function |
| MA50634A (fr) * | 2015-05-22 | 2021-04-28 | Agenebio Inc | Compositions pharmaceutiques à libération prolongée comportant du lévétiracétam |
| CN112843005B (zh) | 2015-05-22 | 2023-02-21 | 艾吉因生物股份有限公司 | 左乙拉西坦的延时释放药物组合物 |
| EP3397253A1 (en) | 2015-12-30 | 2018-11-07 | Adamas Pharmaceuticals, Inc. | Methods and compositions for the treatment of seizure-related disorders |
| HRP20250410T1 (hr) * | 2016-05-20 | 2025-05-23 | Institut Pasteur | Levetiracetam, brivaracetam ili seletracetam, namijenjeni upotrebi u liječenju akutne disfunkcije mozga uzrokovane sepsom |
| US10370561B2 (en) | 2016-06-28 | 2019-08-06 | Prc-Desoto International, Inc. | Urethane/urea-containing bis(alkenyl) ethers, prepolymers prepared using urethane/urea-containing bis(alkenyl) ethers, and uses thereof |
| US11098222B2 (en) | 2018-07-03 | 2021-08-24 | Prc-Desoto International, Inc. | Sprayable polythioether coatings and sealants |
| CN109892247B (zh) * | 2019-04-19 | 2023-08-18 | 桂林医学院 | 一种猫参与的检测大鼠认知功能的实验装置 |
| CN112569216B (zh) * | 2019-09-30 | 2022-02-15 | 厦门大学 | 戊酸衍生物在治疗唐氏综合征中的应用 |
| CN116075302A (zh) * | 2020-07-10 | 2023-05-05 | 艾吉因生物股份有限公司 | GABAAα5激动剂和SV2A抑制剂的组合以及在认知损害的治疗中的使用方法 |
| IL305471A (en) * | 2021-02-26 | 2023-10-01 | Syndesi Therapeutics Sa | Compounds for the treatment of cognitive disorders |
| US20240132513A1 (en) | 2022-08-19 | 2024-04-25 | Agenebio, Inc. | Benzazepine derivatives, compositions, and methods for treating cognitive impairment |
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| GB1039113A (en) | 1964-08-06 | 1966-08-17 | Ucb Sa | New n-substituted lactams |
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| IT1045043B (it) * | 1975-08-13 | 1980-04-21 | Isf Spa | Derivati pirrolidinici |
| IT1075280B (it) * | 1977-02-11 | 1985-04-22 | Isf Spa | Procedimento per la preparazione di derivati pirrolidinici |
| BE864269A (fr) * | 1977-03-03 | 1978-06-16 | Parke Davis & Co | Nouveaux n-(aminoalkyl substitue)-2-oxo-1-pyrrolidine-acetamides et procedes pour les produire |
| DE2960194D1 (en) * | 1978-05-08 | 1981-04-16 | Ucb Sa | Lactam-n-acetic acids, their amides, process for their preparation and therapeutic compositions containing them |
| US4654370A (en) | 1979-03-12 | 1987-03-31 | Abbott Laboratories | Glyceryl valproates |
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| IT1190133B (it) * | 1986-06-19 | 1988-02-10 | Chiesi Farma Spa | Derivati di acido valproico e di acido (e)-2-valproenoico,procedimento per la loro preparazione e relative composizioni farmaceutiche |
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| WO2009109547A1 (en) * | 2008-03-03 | 2009-09-11 | Ucb Pharma, S.A. | Pharmaceutical solutions, process of preparation and therapeutic uses |
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| ES2865504T3 (es) | 2008-10-16 | 2021-10-15 | Univ Johns Hopkins | Procedimientos y composiciones para la mejora de la función cognitiva |
| US9125898B2 (en) * | 2008-11-14 | 2015-09-08 | Neurotune Ag | Acetam derivatives for pain relief |
| HUE032275T2 (en) | 2008-11-18 | 2017-09-28 | Ucb Biopharma Sprl | Sustained release formulations containing a 2-oxo-pyrrolidine derivative |
| AU2010209790B2 (en) | 2009-01-29 | 2014-01-16 | Ucb Pharma, S.A. | Pharmaceutical compositions comprising 2-oxo-1-pyrrolidine derivatives |
| EP2393483B1 (en) | 2009-02-09 | 2017-06-28 | UCB Biopharma SPRL | Pharmaceutical compositions comprising brivaracetam |
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-
2009
- 2009-10-16 ES ES17167125T patent/ES2865504T3/es active Active
- 2009-10-16 JP JP2011532085A patent/JP5917148B2/ja active Active
- 2009-10-16 ES ES09748527.0T patent/ES2637497T3/es active Active
- 2009-10-16 EP EP17167125.8A patent/EP3260118B1/en active Active
- 2009-10-16 BR BRPI0920342-7A patent/BRPI0920342A2/pt not_active Application Discontinuation
- 2009-10-16 AU AU2009303834A patent/AU2009303834B2/en active Active
- 2009-10-16 DK DK17167125.8T patent/DK3260118T3/da active
- 2009-10-16 CA CA2740610A patent/CA2740610C/en active Active
- 2009-10-16 EP EP09748527.0A patent/EP2346500B1/en active Active
- 2009-10-16 EA EA201170571A patent/EA033130B1/ru not_active IP Right Cessation
- 2009-10-16 US US12/580,464 patent/US20100099735A1/en not_active Abandoned
- 2009-10-16 CN CN201710440380.4A patent/CN107243007A/zh active Pending
- 2009-10-16 CN CN2009801474233A patent/CN102227217A/zh active Pending
- 2009-10-16 WO PCT/US2009/005647 patent/WO2010044878A1/en not_active Ceased
- 2009-10-16 DK DK09748527.0T patent/DK2346500T3/en active
-
2011
- 2011-11-02 US US13/287,531 patent/US8604075B2/en active Active
-
2014
- 2014-04-25 US US14/261,962 patent/US20150094352A1/en not_active Abandoned
- 2014-06-24 JP JP2014129145A patent/JP2014169339A/ja not_active Withdrawn
-
2016
- 2016-05-25 JP JP2016103917A patent/JP6271641B2/ja active Active
-
2018
- 2018-04-06 HK HK18104537.2A patent/HK1245099A1/zh unknown
-
2021
- 2021-08-17 US US17/404,124 patent/US20220218665A1/en not_active Abandoned
-
2023
- 2023-10-03 US US18/376,127 patent/US20240293363A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| ES2865504T3 (es) | 2021-10-15 |
| EA033130B1 (ru) | 2019-08-30 |
| JP2014169339A (ja) | 2014-09-18 |
| JP6271641B2 (ja) | 2018-01-31 |
| WO2010044878A1 (en) | 2010-04-22 |
| DK3260118T3 (da) | 2021-04-19 |
| CA2740610A1 (en) | 2010-04-22 |
| AU2009303834A1 (en) | 2010-04-22 |
| JP2016147915A (ja) | 2016-08-18 |
| DK2346500T3 (en) | 2017-07-17 |
| JP2012505883A (ja) | 2012-03-08 |
| HK1248543A1 (en) | 2018-10-19 |
| US8604075B2 (en) | 2013-12-10 |
| JP5917148B2 (ja) | 2016-05-11 |
| US20100099735A1 (en) | 2010-04-22 |
| ES2637497T3 (es) | 2017-10-13 |
| EA201170571A1 (ru) | 2011-12-30 |
| CN102227217A (zh) | 2011-10-26 |
| EP2346500B1 (en) | 2017-05-17 |
| EP3260118A1 (en) | 2017-12-27 |
| US20120046336A1 (en) | 2012-02-23 |
| US20150094352A1 (en) | 2015-04-02 |
| EP3260118B1 (en) | 2021-03-24 |
| US20240293363A1 (en) | 2024-09-05 |
| CN107243007A (zh) | 2017-10-13 |
| BRPI0920342A2 (pt) | 2020-06-23 |
| AU2009303834B2 (en) | 2016-08-11 |
| US20220218665A1 (en) | 2022-07-14 |
| EP2346500A1 (en) | 2011-07-27 |
| CA2740610C (en) | 2020-01-07 |
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