HK1243000A1 - 用於增强PPARγ表現及核轉位之化合物及其醫療用途 - Google Patents
用於增强PPARγ表現及核轉位之化合物及其醫療用途Info
- Publication number
- HK1243000A1 HK1243000A1 HK18102703.4A HK18102703A HK1243000A1 HK 1243000 A1 HK1243000 A1 HK 1243000A1 HK 18102703 A HK18102703 A HK 18102703A HK 1243000 A1 HK1243000 A1 HK 1243000A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- enhancing
- compounds
- therapeutic use
- nuclear translocation
- pparγ expression
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
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- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
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- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Obesity (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Immunology (AREA)
- Dispersion Chemistry (AREA)
- Endocrinology (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- Rheumatology (AREA)
- Reproductive Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Psychiatry (AREA)
- Vascular Medicine (AREA)
- Transplantation (AREA)
- Hospice & Palliative Care (AREA)
- Gynecology & Obstetrics (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562108564P | 2015-01-28 | 2015-01-28 | |
PCT/CN2016/072347 WO2016119701A1 (en) | 2015-01-28 | 2016-01-27 | COMPOUNDS FOR ENHANCING PPARγ EXPRESSION AND NUCLEAR TRANSLOCATION AND THERAPEUTIC USE THEREOF |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1243000A1 true HK1243000A1 (zh) | 2018-07-06 |
Family
ID=56542433
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK18102703.4A HK1243000A1 (zh) | 2015-01-28 | 2018-02-26 | 用於增强PPARγ表現及核轉位之化合物及其醫療用途 |
Country Status (9)
Country | Link |
---|---|
US (1) | US20180015090A1 (zh) |
EP (1) | EP3250201A4 (zh) |
JP (1) | JP6925272B2 (zh) |
CN (2) | CN115282152A (zh) |
AU (1) | AU2016212527B2 (zh) |
CA (1) | CA2975000A1 (zh) |
HK (1) | HK1243000A1 (zh) |
TW (1) | TWI725008B (zh) |
WO (1) | WO2016119701A1 (zh) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111346228B (zh) * | 2018-12-21 | 2022-01-14 | 广州市妇女儿童医疗中心 | 胃肠道疾病的免疫机制及治疗药物 |
CN114432451B (zh) * | 2018-12-21 | 2024-02-09 | 广州市妇女儿童医疗中心 | 胃肠道疾病的免疫机制及治疗药物 |
CN113244395B (zh) * | 2020-02-10 | 2024-07-23 | 广州市妇女儿童医疗中心 | 纤维化疾病机制及其治疗药物 |
WO2021222231A1 (en) * | 2020-04-27 | 2021-11-04 | The Research Institute At Nationwide Children's Hospital | PPARγ AGONISTS FOR TREATMENT OF KIDNEY DISEASE |
Family Cites Families (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3031450A (en) * | 1959-04-30 | 1962-04-24 | Thomae Gmbh Dr K | Substituted pyrimido-[5, 4-d]-pyrimidines |
GB8813032D0 (en) * | 1988-06-02 | 1988-07-06 | Boehringer Ingelheim Int | Antiviral pharmaceutical composition |
IT1239064B (it) * | 1990-05-14 | 1993-09-20 | Fidia Spa | Uso terapeutico del dipiridamolo |
AU6516494A (en) * | 1993-04-15 | 1994-11-08 | New York University | Adenosine receptor agonists for the promotion of wound healing |
US20020025969A1 (en) * | 1997-07-09 | 2002-02-28 | Wolf-Georg Forssmann | Use of phosphordiesterase inhibitors in the treatment of prostatic diseases |
US6548490B1 (en) * | 1997-10-28 | 2003-04-15 | Vivus, Inc. | Transmucosal administration of phosphodiesterase inhibitors for the treatment of erectile dysfunction |
CA2378257A1 (en) * | 1999-08-10 | 2001-02-15 | William E. Sponsel | Method for increasing optic nerve, choroidal and retinal blood flow to facilitate the preservation of sight |
EP1093814A1 (en) * | 1999-10-22 | 2001-04-25 | Boehringer Ingelheim Pharma KG | Use of dipyridamole or mopidamol in the manufacture of a medicament for the treatment and prevention of fibrin-dependent microcirculation disorders |
FR2802414B1 (fr) * | 1999-12-20 | 2003-06-27 | G Pharm Lab | Composition, notamment cosmetique ou dermatologique, contenant des oligosaccharides, son procede de preparation et un procede de traitement cosmetique |
AU2002229573A1 (en) * | 2000-12-19 | 2002-07-01 | Merck Patent Gmbh | Pharmaceutical formulation containing pyrazolo(4,3-D)pyrimidines and antithrombotic agents, calcium-antagonists, prostaglandins or prostaglandin derivatives |
DE10119680A1 (de) * | 2001-04-20 | 2002-11-14 | Boehringer Ingelheim Pharma | Verwendung von Radikalfänger-Verbindungen zur Behandlung und Verhinderung von no-abhängigen Störungen der Mikrozirkulation |
PL370764A1 (en) * | 2001-10-05 | 2005-05-30 | Combinatorx, Incorporated | Combinations for the treatment of immunoinflammatory disorders |
US20030181461A1 (en) * | 2002-01-25 | 2003-09-25 | Lautt Wilfred Wayne | Use of phosphodiesterase antagonists to treat insulin resistance |
EP1594503A2 (en) * | 2003-02-07 | 2005-11-16 | Boehringer Ingelheim International GmbH | Use of dipyridamole or mopidamole for treatment and prevention of mmp-9-dependent disorders |
DE10306179A1 (de) * | 2003-02-13 | 2004-08-26 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verwendung von Dipyridamol in Kombination mit Acetylsalicylsäure und einem Angiotensin II-Antagonisten zur Schlaganfall-Prophylaxe |
CA2437709A1 (en) * | 2003-08-08 | 2005-02-20 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Use of dipyridamole, acetylsalicylic acid and an angiotensin ii antagonist for treatment and prevention of vascular events |
US8784881B2 (en) * | 2004-03-05 | 2014-07-22 | Board Of Regents, The University Of Texas System | Liposomal curcumin for treatment of diseases |
GB0412526D0 (en) * | 2004-06-05 | 2004-07-14 | Leuven K U Res & Dev | Type 2 diabetes |
CN1969939A (zh) * | 2005-11-23 | 2007-05-30 | 北京奇源益德药物研究所 | 治疗心脑血管疾病的药物组合物及其制备方法和质控方法 |
US7556606B2 (en) * | 2006-05-18 | 2009-07-07 | Massachusetts Institute Of Technology | Pelvis interface |
DE102007008484A1 (de) * | 2007-02-19 | 2008-08-21 | Epo Experimentelle Pharmakologie & Onkologie Berlin-Buch Gmbh | Pharmazeutische Zubereitung zur Bekämpfung von Metastasen |
US20110189293A1 (en) * | 2007-12-17 | 2011-08-04 | CombinatoRx, Incoporated | Therapeutic regimens for the treatment of immunoinflammatory disorders |
US20110244028A1 (en) * | 2008-09-26 | 2011-10-06 | Steve Leigh | Method of solubilizing biologically active compounds |
KR20100111839A (ko) * | 2009-04-08 | 2010-10-18 | 인제대학교 산학협력단 | 다이피리다몰을 포함하는 이상지질혈증 관련 질환 예방 또는 치료용 조성물 |
WO2011038298A1 (en) * | 2009-09-25 | 2011-03-31 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Use of dipyridamole in chronic ischemia |
CN101780037B (zh) * | 2010-02-03 | 2011-11-16 | 南昌大学 | 双嘧达莫自乳化给药系统及其制备方法 |
TWI510256B (zh) * | 2012-03-23 | 2015-12-01 | Univ Chang Gung | Used in the treatment of thrombotic diseases of magnetic nano drugs |
IL225179A (en) * | 2013-03-12 | 2017-01-31 | Rogosnitzky Moshe | Compounds for use in ocular disorders using dipyridamole |
CN104971043B (zh) * | 2014-04-02 | 2017-12-12 | 贵州益佰制药股份有限公司 | 一种银杏达莫脂质体药物制剂及其制备方法 |
-
2016
- 2016-01-27 WO PCT/CN2016/072347 patent/WO2016119701A1/en active Application Filing
- 2016-01-27 TW TW105102559A patent/TWI725008B/zh active
- 2016-01-27 US US15/546,949 patent/US20180015090A1/en active Pending
- 2016-01-27 EP EP16742763.2A patent/EP3250201A4/en active Pending
- 2016-01-27 CA CA2975000A patent/CA2975000A1/en active Pending
- 2016-01-27 AU AU2016212527A patent/AU2016212527B2/en active Active
- 2016-01-27 JP JP2017540787A patent/JP6925272B2/ja active Active
- 2016-01-27 CN CN202210997748.8A patent/CN115282152A/zh active Pending
- 2016-01-27 CN CN201680003479.1A patent/CN107106541A/zh active Pending
-
2018
- 2018-02-26 HK HK18102703.4A patent/HK1243000A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
EP3250201A4 (en) | 2018-08-01 |
EP3250201A1 (en) | 2017-12-06 |
US20180015090A1 (en) | 2018-01-18 |
JP6925272B2 (ja) | 2021-08-25 |
TW201642862A (zh) | 2016-12-16 |
CN107106541A (zh) | 2017-08-29 |
CA2975000A1 (en) | 2016-08-04 |
AU2016212527A1 (en) | 2017-08-31 |
JP2018505186A (ja) | 2018-02-22 |
AU2016212527B2 (en) | 2019-03-07 |
WO2016119701A1 (en) | 2016-08-04 |
TWI725008B (zh) | 2021-04-21 |
CN115282152A (zh) | 2022-11-04 |
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