HK1221422A1 - 診斷方法和用於治療成膠質細胞瘤的組合物 - Google Patents

診斷方法和用於治療成膠質細胞瘤的組合物

Info

Publication number
HK1221422A1
HK1221422A1 HK16109700.4A HK16109700A HK1221422A1 HK 1221422 A1 HK1221422 A1 HK 1221422A1 HK 16109700 A HK16109700 A HK 16109700A HK 1221422 A1 HK1221422 A1 HK 1221422A1
Authority
HK
Hong Kong
Prior art keywords
glioblastoma
compositions
treatment
diagnostic methods
diagnostic
Prior art date
Application number
HK16109700.4A
Other languages
English (en)
Chinese (zh)
Inventor
Carlos Bais
Richard Bourgon
Heidi Phillips
Thomas Sandmann
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of HK1221422A1 publication Critical patent/HK1221422A1/zh

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Hematology (AREA)
  • Mycology (AREA)
  • General Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
HK16109700.4A 2013-08-30 2016-08-15 診斷方法和用於治療成膠質細胞瘤的組合物 HK1221422A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361872346P 2013-08-30 2013-08-30
PCT/US2014/053500 WO2015031808A2 (fr) 2013-08-30 2014-08-29 Procédés de diagnostic et compositions pour le traitement d'un glioblastome

Publications (1)

Publication Number Publication Date
HK1221422A1 true HK1221422A1 (zh) 2017-06-02

Family

ID=52583566

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16109700.4A HK1221422A1 (zh) 2013-08-30 2016-08-15 診斷方法和用於治療成膠質細胞瘤的組合物

Country Status (15)

Country Link
US (1) US10456470B2 (fr)
EP (1) EP3038646B1 (fr)
JP (2) JP6664323B2 (fr)
KR (1) KR20160048196A (fr)
CN (1) CN105611940A (fr)
AR (1) AR097500A1 (fr)
AU (1) AU2014312079B2 (fr)
BR (1) BR112016004305A2 (fr)
CA (1) CA2921515A1 (fr)
HK (1) HK1221422A1 (fr)
IL (1) IL244089A0 (fr)
MX (1) MX2016002423A (fr)
RU (1) RU2706968C2 (fr)
SG (1) SG11201601471SA (fr)
WO (1) WO2015031808A2 (fr)

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JP2017523776A (ja) 2014-07-14 2017-08-24 ジェネンテック， インコーポレイテッド 膠芽腫の診断方法及びその治療用組成物
WO2017025962A1 (fr) * 2015-08-10 2017-02-16 Tel Hashomer Medical Research, Infrastructure And Services Ltd Prédiction de la réponse à une immunothérapie basée sur des biomarqueurs tumoraux
CA2940470C (fr) * 2015-09-18 2019-08-20 Signpath Pharma Inc. Traitement de glioblastome
WO2017079695A1 (fr) * 2015-11-05 2017-05-11 Tocagen Inc. Profils d'expression génique pour prédire la réactivité à une virothérapie dans des indications cancéreuses
AU2016381964B2 (en) 2015-12-30 2024-02-15 Kodiak Sciences Inc. Antibodies and conjugates thereof
CN106874647B (zh) * 2017-01-06 2019-03-22 吴安华 一种脑胶质母细胞瘤患者生存期预测系统
WO2019155050A1 (fr) * 2018-02-12 2019-08-15 F. Hoffmann-La Roche Ag Procédé de prédiction de réponse à une thérapie par évaluation de l'hétérogénéité génétique tumorale
CN112203679A (zh) 2018-03-02 2021-01-08 科达制药股份有限公司 Il-6抗体及其融合构建体和缀合物
CA3126828A1 (fr) 2019-01-23 2020-07-30 The Regents Of The Universtiy Of Michigan Procedes et systeme pour la reconstruction de reseaux de maladie et de reponse a des medicaments et leurs utilisations
CN109762903B (zh) * 2019-01-31 2022-02-01 山东大学齐鲁医院 miR-1246和/或TERF2IP在诊治胶质瘤中的应用
KR102256859B1 (ko) * 2019-03-12 2021-05-27 건국대학교 산학협력단 알츠하이머병의 진단용 조성물
KR102078500B1 (ko) * 2019-03-12 2020-02-17 건국대학교 산학협력단 알츠하이머병의 진단용 조성물
CN113811770B (zh) * 2019-05-13 2024-06-28 豪夫迈·罗氏有限公司 抑制干扰的药代动力学免疫测定
CN110412277B (zh) * 2019-06-26 2022-09-09 四川大学华西医院 Snap91自身抗体检测试剂在制备肺癌筛查试剂盒中的用途
WO2021034091A1 (fr) * 2019-08-19 2021-02-25 재단법인 아산사회복지재단 Méthode de traitement du glioblastome
CN114786731A (zh) 2019-10-10 2022-07-22 科达制药股份有限公司 治疗眼部病症的方法
CN111996251B (zh) * 2020-06-19 2024-03-26 皖南医学院第一附属医院（皖南医学院弋矶山医院） 一种恶性胶质瘤生物标志物的应用
CN114075604B (zh) * 2022-01-18 2022-04-08 天津医科大学总医院 胶质母细胞瘤预后预测评分模型及其在指导临床精准诊疗中的应用

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Also Published As

Publication number Publication date
SG11201601471SA (en) 2016-03-30
BR112016004305A2 (pt) 2017-10-17
RU2016111161A (ru) 2017-10-05
WO2015031808A3 (fr) 2015-04-23
CA2921515A1 (fr) 2015-03-05
JP6664323B2 (ja) 2020-03-13
US10456470B2 (en) 2019-10-29
CN105611940A (zh) 2016-05-25
EP3038646B1 (fr) 2020-03-04
JP2020062012A (ja) 2020-04-23
IL244089A0 (en) 2016-04-21
AU2014312079B2 (en) 2020-01-16
KR20160048196A (ko) 2016-05-03
JP2016529903A (ja) 2016-09-29
AR097500A1 (es) 2016-03-16
EP3038646A2 (fr) 2016-07-06
RU2706968C2 (ru) 2019-11-21
EP3038646A4 (fr) 2017-07-12
AU2014312079A1 (en) 2016-03-03
WO2015031808A2 (fr) 2015-03-05
US20150064178A1 (en) 2015-03-05
MX2016002423A (es) 2016-08-19

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