HK1220737A1 - 短端粒丰度的量度 - Google Patents
短端粒丰度的量度Info
- Publication number
- HK1220737A1 HK1220737A1 HK16108844.3A HK16108844A HK1220737A1 HK 1220737 A1 HK1220737 A1 HK 1220737A1 HK 16108844 A HK16108844 A HK 16108844A HK 1220737 A1 HK1220737 A1 HK 1220737A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- measures
- short telomere
- telomere abundance
- abundance
- short
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361826484P | 2013-05-22 | 2013-05-22 | |
PCT/US2014/039110 WO2014190138A2 (en) | 2013-05-22 | 2014-05-22 | Measures of short telomere abundance |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1220737A1 true HK1220737A1 (zh) | 2017-05-12 |
Family
ID=51934344
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK16108844.3A HK1220737A1 (zh) | 2013-05-22 | 2016-07-25 | 短端粒丰度的量度 |
Country Status (10)
Country | Link |
---|---|
US (2) | US10316366B2 (zh) |
EP (1) | EP2999800B1 (zh) |
JP (1) | JP6546158B2 (zh) |
CN (1) | CN105283559A (zh) |
AU (1) | AU2014268510A1 (zh) |
CA (1) | CA2912216A1 (zh) |
ES (1) | ES2762860T3 (zh) |
HK (1) | HK1220737A1 (zh) |
MX (1) | MX2015015891A (zh) |
WO (1) | WO2014190138A2 (zh) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9169516B2 (en) | 2003-01-24 | 2015-10-27 | University Of Utah Research Foundation | Methods of predicting mortality risk by determining telomere length |
US9689028B2 (en) | 2008-12-22 | 2017-06-27 | University Of Utah Foundation | Monochrome multiplex quantitative PCR |
MX2015015891A (es) | 2013-05-22 | 2016-06-02 | Telomere Diagnostics Inc | Mediciones de abundancia de telomeros cortos. |
BR112017014116A2 (pt) * | 2014-12-30 | 2018-03-06 | Telomere Diagnostics Inc | pcr quantitativo multiplex |
CN106480218A (zh) * | 2016-12-13 | 2017-03-08 | 浙江指针基因科技有限公司 | 一种基于qPCR法检测白细胞端粒长度的方法 |
US10604794B2 (en) | 2017-05-10 | 2020-03-31 | The Board Of Regents Of The University Of Texas System | Method to measure the shortest telomeres |
CN107164365B (zh) * | 2017-06-16 | 2020-11-27 | 广州普麦健康咨询有限公司 | 应用三代测序技术检测染色体端粒dna全长的方法 |
EP3674418A1 (en) * | 2018-12-26 | 2020-07-01 | Life Length S.L. | Method for measuring telomere associated variables and uses thereof for the diagnosis and/or prognosis of telomeric-associated diseases |
CN112029841B (zh) * | 2019-06-03 | 2024-02-09 | 香港中文大学 | 定量端粒长度和基因组基序的方法 |
US11227691B2 (en) | 2019-09-03 | 2022-01-18 | Kpn Innovations, Llc | Systems and methods for selecting an intervention based on effective age |
US11250337B2 (en) | 2019-11-04 | 2022-02-15 | Kpn Innovations Llc | Systems and methods for classifying media according to user negative propensities |
CN113862336A (zh) * | 2021-11-03 | 2021-12-31 | 天津医科大学 | 一种基于单基因校正的高通量斑点杂交端粒长度检测方法 |
CN117248003B (zh) * | 2023-11-13 | 2024-04-12 | 元码基因科技(北京)股份有限公司 | 用于完整端粒扩增子测序的组合物、预文库及其构建方法 |
CN117230171B (zh) * | 2023-11-13 | 2024-04-12 | 元码基因科技(北京)股份有限公司 | 端粒扩增子测序用试剂盒及预文库构建方法 |
CN117230169B (zh) * | 2023-11-13 | 2024-02-13 | 元码基因科技(北京)股份有限公司 | 用于长片段端粒序列测序的接头、预文库及其构建方法 |
Family Cites Families (68)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS608745B2 (ja) | 1978-02-14 | 1985-03-05 | 三洋化成工業株式会社 | 免疫活性物質−つや消しガラス複合体,その製造法及び該複合体を含有してなる測定試薬 |
US4469863A (en) | 1980-11-12 | 1984-09-04 | Ts O Paul O P | Nonionic nucleic acid alkyl and aryl phosphonates and processes for manufacture and use thereof |
EP0155747A1 (en) | 1984-03-19 | 1985-09-25 | Kidde, Inc. | Tube culture system |
US5034506A (en) | 1985-03-15 | 1991-07-23 | Anti-Gene Development Group | Uncharged morpholino-based polymers having achiral intersubunit linkages |
US5235033A (en) | 1985-03-15 | 1993-08-10 | Anti-Gene Development Group | Alpha-morpholino ribonucleoside derivatives and polymers thereof |
US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
US5216141A (en) | 1988-06-06 | 1993-06-01 | Benner Steven A | Oligonucleotide analogs containing sulfur linkages |
US5602240A (en) | 1990-07-27 | 1997-02-11 | Ciba Geigy Ag. | Backbone modified oligonucleotide analogs |
US5386023A (en) | 1990-07-27 | 1995-01-31 | Isis Pharmaceuticals | Backbone modified oligonucleotide analogs and preparation thereof through reductive coupling |
US5644048A (en) | 1992-01-10 | 1997-07-01 | Isis Pharmaceuticals, Inc. | Process for preparing phosphorothioate oligonucleotides |
US6020124A (en) | 1992-04-27 | 2000-02-01 | Trustees Of Dartmouth College | Detection of soluble gene sequences in biological fluids |
US5489508A (en) | 1992-05-13 | 1996-02-06 | University Of Texas System Board Of Regents | Therapy and diagnosis of conditions related to telomere length and/or telomerase activity |
US6235470B1 (en) | 1993-11-12 | 2001-05-22 | The Johns Hopkins University School Of Medicine | Detection of neoplasia by analysis of saliva |
US5637684A (en) | 1994-02-23 | 1997-06-10 | Isis Pharmaceuticals, Inc. | Phosphoramidate and phosphorothioamidate oligomeric compounds |
US5512441A (en) | 1994-11-15 | 1996-04-30 | American Health Foundation | Quantative method for early detection of mutant alleles and diagnostic kits for carrying out the method |
US5741677A (en) | 1995-06-07 | 1998-04-21 | Geron Corporation | Methods for measuring telomere length |
US5856096A (en) | 1995-09-20 | 1999-01-05 | Ctrc Research Foundation | Rapid and sensitive assays for detecting and distinguishing between processive and non-processive telomerase activities |
WO1997012681A1 (en) | 1995-10-02 | 1997-04-10 | Analyte Diagnostics, Inc. | Sample collection, recovery and dispensing device for saliva |
DE69637086T2 (de) | 1995-10-12 | 2008-01-10 | Lansdorp, Peter M., Vancouver | Verfahren zum nachweis von mehrfachkopien einer wiederholungssequenz in einem nukleinsäuremolekül |
IN182876B (zh) | 1995-11-22 | 1999-07-31 | Abion Ohg | |
JP3718892B2 (ja) | 1996-02-05 | 2005-11-24 | 三菱化学株式会社 | ヒト・テロメラーゼ活性の測定方法 |
US5945319A (en) | 1996-04-25 | 1999-08-31 | Medtronic, Inc. | Periodate oxidative method for attachment of biomolecules to medical device surfaces |
US5928916A (en) | 1996-04-25 | 1999-07-27 | Medtronic, Inc. | Ionic attachment of biomolecules with a guanidino moiety to medical device surfaces |
US5910122A (en) | 1996-06-04 | 1999-06-08 | Americare Health Scan Inc. | Saliva collector with an aspirating pipette |
HUP9902721A2 (hu) | 1997-11-25 | 1999-12-28 | The Procter & Gamble Co. | Tömény textillágyító készítmény és ehhez alkalmazható magas telítetlenségű textillágyító vegyület |
JP4013333B2 (ja) | 1998-06-05 | 2007-11-28 | 株式会社B&Cラボラトリーズ | 皮膚の老化度の測定方法および測定用キット |
US6022326A (en) | 1998-10-30 | 2000-02-08 | Lifepoint, Inc. | Device and method for automatic collection of whole saliva |
AU764964B2 (en) | 1998-11-23 | 2003-09-04 | Usamriid | Purification method and apparatus |
US6436677B1 (en) | 2000-03-02 | 2002-08-20 | Promega Corporation | Method of reverse transcription |
JP2004533801A (ja) | 2000-03-07 | 2004-11-11 | イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー | 単一および多重標的dnaのためのインターカレーション色素を用いる実時間定量pcr |
EP1399591A2 (en) | 2001-06-23 | 2004-03-24 | University of Wales College of Medicine | Method for the determination of telomere length |
JP2005512578A (ja) | 2001-12-19 | 2005-05-12 | ロシュ ダイアグノスティックス コーポレーション | Pcrをベースとする高効率のポリペプチドスクリーニング |
EP1476561B1 (en) | 2002-01-31 | 2011-11-23 | University of Utah | Amplifying repetitive nucleic acid sequences |
US20100311954A1 (en) | 2002-03-01 | 2010-12-09 | Xencor, Inc. | Optimized Proteins that Target Ep-CAM |
US7482116B2 (en) | 2002-06-07 | 2009-01-27 | Dna Genotek Inc. | Compositions and methods for obtaining nucleic acids from sputum |
GB2391813B (en) | 2002-08-14 | 2006-03-29 | Cozart Bioscience Ltd | An oral fluid collection, transfer and transportation device and method |
AU2003298706A1 (en) | 2002-12-04 | 2004-06-23 | Applera Corporation | Multiplex amplification of polynucleotides |
US9169516B2 (en) | 2003-01-24 | 2015-10-27 | University Of Utah Research Foundation | Methods of predicting mortality risk by determining telomere length |
US20050009097A1 (en) | 2003-03-31 | 2005-01-13 | Better Marc D. | Human engineered antibodies to Ep-CAM |
JP4228041B2 (ja) | 2003-07-08 | 2009-02-25 | 東洋紡績株式会社 | 塩基多型の検出方法 |
US20050180979A1 (en) | 2004-02-13 | 2005-08-18 | Micromet Ag | Anti-EpCAM immunoglobulins |
US20060141492A1 (en) | 2004-07-27 | 2006-06-29 | Sowers Kevin R | Gene probes for the selective detection of microorganisms that reductively dechlorinate polychlorinated biphenyl compounds |
US20080182252A1 (en) | 2005-04-08 | 2008-07-31 | Linkage Biosciences, Inc. | Genotyping Hla Loci |
EP1876893B1 (en) | 2005-04-15 | 2012-04-11 | Geron Corporation | Cancer treatment by combined inhibition of proteasome and telomerase activities |
WO2007008943A2 (en) | 2005-07-08 | 2007-01-18 | Xencor, Inc. | Optimized anti-ep-cam antibodies |
US20070059716A1 (en) | 2005-09-15 | 2007-03-15 | Ulysses Balis | Methods for detecting fetal abnormality |
CA2632614C (en) | 2005-12-09 | 2014-04-01 | Dna Genotek Inc. | Container system for releasably storing a substance |
US20070161031A1 (en) * | 2005-12-16 | 2007-07-12 | The Board Of Trustees Of The Leland Stanford Junior University | Functional arrays for high throughput characterization of gene expression regulatory elements |
WO2008143679A2 (en) | 2006-06-01 | 2008-11-27 | Verenium Corporation | Nucleic acids and proteins and methods for making and using them |
US20080063628A1 (en) | 2006-09-11 | 2008-03-13 | Davis Janet E | Methods to promote cell differentiation |
KR101683884B1 (ko) | 2007-04-04 | 2016-12-07 | 시구마-토우인더스트리에파아마슈우티히리유니트에스.피이.에이. | 항-EpCAM 항체 및 이의 용도 |
US20090142408A1 (en) | 2007-07-23 | 2009-06-04 | Telomolecular Corporation | Telomerase delivery by biodegradable Nanoparticle |
EP2191013A1 (en) * | 2007-08-10 | 2010-06-02 | Tina Holding APS | Method for estimating telomere length |
CN201188066Y (zh) | 2008-02-03 | 2009-01-28 | 上海邃志生物科技有限公司 | 一种能储存试剂的唾液采集装置 |
US9079181B2 (en) | 2008-08-21 | 2015-07-14 | Dna Genotek Inc. | Sample receiving device |
JP5519511B2 (ja) | 2008-09-08 | 2014-06-11 | アークレイ株式会社 | 試料採取用具 |
US9689028B2 (en) | 2008-12-22 | 2017-06-27 | University Of Utah Foundation | Monochrome multiplex quantitative PCR |
US8039215B2 (en) | 2009-03-10 | 2011-10-18 | Roche Molecular Systems, Inc. | Multiplex quantitative nucleic acid amplification and melting assay |
WO2010115156A2 (en) | 2009-04-03 | 2010-10-07 | Synthetic Genomics, Inc. | Endophytic fungus and uses therefor |
EP2280080A1 (en) | 2009-07-31 | 2011-02-02 | Qiagen GmbH | Method of normalized quantification of nucleic acids using anchor oligonucleotides and adapter oligonucleotides |
US20110207128A1 (en) | 2010-02-16 | 2011-08-25 | Cawthon Richard M | Methods and kits for determining biological age and longevity based on gene expression profiles |
US20130011918A1 (en) | 2010-02-17 | 2013-01-10 | Biotime Inc. | Methods for telomere length and genomic dna quality control and analysis in pluripotent stem cells |
CA2830673C (en) | 2011-03-28 | 2019-11-12 | Hui Wang | Telomere length measurement in formalin-fixed, paraffin embedded (ffpe) samples by quantitative pcr |
WO2013102116A1 (en) | 2011-12-31 | 2013-07-04 | Telome Health, Inc. | Saliva-derived measures of telomere abundance and sample collection device |
US10093970B2 (en) | 2013-03-15 | 2018-10-09 | New York University | Method for single cell analysis of telomere length using pre-amplification and multiple-copy reference sequence |
MX2015015891A (es) | 2013-05-22 | 2016-06-02 | Telomere Diagnostics Inc | Mediciones de abundancia de telomeros cortos. |
BR112017014116A2 (pt) | 2014-12-30 | 2018-03-06 | Telomere Diagnostics Inc | pcr quantitativo multiplex |
-
2014
- 2014-05-22 MX MX2015015891A patent/MX2015015891A/es unknown
- 2014-05-22 EP EP14800611.7A patent/EP2999800B1/en active Active
- 2014-05-22 CN CN201480029826.9A patent/CN105283559A/zh active Pending
- 2014-05-22 JP JP2016515077A patent/JP6546158B2/ja not_active Expired - Fee Related
- 2014-05-22 AU AU2014268510A patent/AU2014268510A1/en not_active Abandoned
- 2014-05-22 CA CA2912216A patent/CA2912216A1/en not_active Abandoned
- 2014-05-22 WO PCT/US2014/039110 patent/WO2014190138A2/en active Application Filing
- 2014-05-22 ES ES14800611T patent/ES2762860T3/es active Active
- 2014-05-22 US US14/892,395 patent/US10316366B2/en not_active Expired - Fee Related
-
2016
- 2016-07-25 HK HK16108844.3A patent/HK1220737A1/zh unknown
-
2019
- 2019-06-10 US US16/436,357 patent/US20190382841A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CA2912216A1 (en) | 2014-11-27 |
WO2014190138A3 (en) | 2015-02-26 |
US10316366B2 (en) | 2019-06-11 |
JP6546158B2 (ja) | 2019-07-17 |
EP2999800A4 (en) | 2017-01-04 |
US20190382841A1 (en) | 2019-12-19 |
CN105283559A (zh) | 2016-01-27 |
ES2762860T3 (es) | 2020-05-26 |
US20160090630A1 (en) | 2016-03-31 |
MX2015015891A (es) | 2016-06-02 |
EP2999800A2 (en) | 2016-03-30 |
JP2016521548A (ja) | 2016-07-25 |
EP2999800B1 (en) | 2019-09-25 |
WO2014190138A2 (en) | 2014-11-27 |
AU2014268510A1 (en) | 2015-11-26 |
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