HK1218958A1 - 仿生流體處理的系統和方法 - Google Patents

仿生流體處理的系統和方法

Info

Publication number
HK1218958A1
HK1218958A1 HK16106975.8A HK16106975A HK1218958A1 HK 1218958 A1 HK1218958 A1 HK 1218958A1 HK 16106975 A HK16106975 A HK 16106975A HK 1218958 A1 HK1218958 A1 HK 1218958A1
Authority
HK
Hong Kong
Prior art keywords
fluid processing
biomimetic
biomimetic fluid
processing
fluid
Prior art date
Application number
HK16106975.8A
Other languages
English (en)
Inventor
‧伊塔利亞諾
‧瑪祖提斯
‧松
‧維茨
Original Assignee
Brigham & Womens Hospital Inc
Univ Vilnius
Harvard College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Brigham & Womens Hospital Inc, Univ Vilnius, Harvard College filed Critical Brigham & Womens Hospital Inc
Publication of HK1218958A1 publication Critical patent/HK1218958A1/zh

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502753—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502746—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502776—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for focusing or laminating flows
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/16—Microfluidic devices; Capillary tubes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/20—Material Coatings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/02—Membranes; Filters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/04—Filters; Permeable or porous membranes or plates, e.g. dialysis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/10—Perfusion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/20—Degassing; Venting; Bubble traps
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/36—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of biomass, e.g. colony counters or by turbidity measurements
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/40—Means for regulation, monitoring, measurement or control, e.g. flow regulation of pressure
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0668—Trapping microscopic beads
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/08—Regulating or influencing the flow resistance
    • B01L2400/084—Passive control of flow resistance
    • B01L2400/086—Passive control of flow resistance using baffles or other fixed flow obstructions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/22—Haematology
    • G01N2800/222—Platelet disorders
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/491—Blood by separating the blood components
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
HK16106975.8A 2013-01-03 2016-06-17 仿生流體處理的系統和方法 HK1218958A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361848424P 2013-01-03 2013-01-03
PCT/US2013/070910 WO2014107240A1 (en) 2013-01-03 2013-11-20 System and method for a biomimetic fluid processing

Publications (1)

Publication Number Publication Date
HK1218958A1 true HK1218958A1 (zh) 2017-03-17

Family

ID=51062414

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16106975.8A HK1218958A1 (zh) 2013-01-03 2016-06-17 仿生流體處理的系統和方法

Country Status (8)

Country Link
US (5) US9795965B2 (zh)
EP (2) EP2941642B1 (zh)
JP (1) JP6429794B2 (zh)
CN (1) CN105308452B (zh)
AU (1) AU2013371589C1 (zh)
CA (1) CA2896997C (zh)
HK (1) HK1218958A1 (zh)
WO (1) WO2014107240A1 (zh)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6429794B2 (ja) * 2013-01-03 2018-11-28 ブリガム・アンド・ウイミンズ・ホスピタル・インコーポレイテッド バイオミメティック流体プロセスの系および方法
US9909102B2 (en) 2013-11-19 2018-03-06 Platod Fluidic device for producing platelets
US10590373B2 (en) 2014-03-31 2020-03-17 Brigham And Women's Hospital, Inc. Systems and methods for biomimetic fluid processing
CA2955172C (en) * 2014-07-14 2021-07-20 President And Fellows Of Havard College Systems and methods for improved performance of fluidic and microfluidic systems
CA2966623C (en) 2014-11-03 2024-02-20 The General Hospital Corporation Concentrating particles in a microfluidic device
US9996920B2 (en) * 2014-12-09 2018-06-12 Berkeley Lights, Inc. Automated detection and repositioning of micro-objects in microfluidic devices
GB2555319A (en) * 2015-05-22 2018-04-25 Harvard College Methods, systems, and compositions for determining blood clot formation, and uses thereof
JP6859351B2 (ja) * 2015-09-08 2021-04-14 ブリガム・アンド・ウイミンズ・ホスピタル・インコーポレイテッド 血小板を産生するためのシステムおよび方法
JP6846434B2 (ja) * 2016-04-29 2021-03-24 クレオプティクス・アーゲーＣｒｅｏｐｔｉｘ Ａｇ 分子を回収するための方法およびアセンブリ
EP3545074A1 (en) 2016-11-23 2019-10-02 The Charles Stark Draper Laboratory Inc. Bi-layer multi-well cell culture platform
US20200017812A1 (en) * 2017-03-07 2020-01-16 Platelet Biogenesis, Inc. Recirculating Bioreactor
CN107723207B (zh) * 2017-11-01 2019-01-01 深圳市瑞格生物科技有限公司 一种分离捕获细胞的芯片及其在肿瘤细胞分选中的应用
KR102214461B1 (ko) * 2018-03-06 2021-02-09 사회복지법인 삼성생명공익재단 약물 반응성 검사 장치
EP3824069A4 (en) * 2018-07-19 2022-04-27 Platelet Biogenesis, Inc. STACKED FEEDBACK BIOREACTOR
WO2022167676A1 (en) 2021-02-08 2022-08-11 Hemostod Sa Use of 3d porous structure for platelet production
FR3122185A1 (fr) 2021-04-21 2022-10-28 Institut National De La Sante Et De La Recherche Medicale (Inserm) Procede de liberation de plaquettes en regime turbulent et systeme de liberation de plaquettes pour la mise en œuvre de ce procede

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2076742C1 (ru) 1991-06-17 1997-04-10 Тютрин Иван Илларионович Колонка для гемосорбции
EP0869835B1 (en) 1995-04-13 2005-06-08 Travenol Laboratories (Israel) Ltd. Leukocyte filtration method and apparatus
US20050009101A1 (en) * 2001-05-17 2005-01-13 Motorola, Inc. Microfluidic devices comprising biochannels
DE10207623B4 (de) 2002-02-22 2004-05-06 Siemens Ag Verfahren für die Computertomographie sowie Computertomographie (CT)-Gerät
US7790443B2 (en) * 2002-08-27 2010-09-07 Vanderbilt University Bioreactors with substance injection capacity
US7476326B2 (en) 2003-09-26 2009-01-13 Ahn Chong H On-chip sample preparation for whole blood analysis
US9198645B2 (en) 2003-11-26 2015-12-01 The United States of America, as represented by the Secretary of Commerce of The National Institute of Standards and Technology Controlled vesicle self-assembly in continuous two phase flow microfluidic channels
BRPI0418326A (pt) 2003-12-30 2007-05-02 Bionethos Holding Gmbh método de regeneração de tecidos
CN2726112Y (zh) * 2004-03-12 2005-09-14 南京理工大学 仿蜂巢结构分形微管道网络换热器
RU2246258C1 (ru) 2004-03-16 2005-02-20 Центральный научно-исследовательский рентгено-радиологический институт МЗ РФ Способ диагностики стенозов коронарных артерий
WO2006001954A2 (en) 2004-05-20 2006-01-05 Puget Sound Blood Center And Program Methods for promoting the formation of platelets and for treating blood and bone marrow disorders
US20070243608A1 (en) 2006-04-14 2007-10-18 Board Of Regents, The University Of Texas System Platelet bioreactor
US7718420B2 (en) 2006-10-10 2010-05-18 Postech Academy-Industry Foundation Microfluidic biochip for blood typing based on agglutination reaction
JP2008301746A (ja) 2007-06-06 2008-12-18 Canon Inc 培養装置
EP2040073A1 (en) 2007-09-20 2009-03-25 Iline Microsystems, S.L. Microfluidic device and method for fluid clotting time determination
US20100041128A1 (en) 2008-01-08 2010-02-18 Medtrain Technologies, Llc Microfluidic Device for Application of Shear Stress and Tensile Strain
JP5419076B2 (ja) * 2008-05-15 2014-02-19 旭化成メディカル株式会社 血小板の誘導方法
WO2010005467A2 (en) * 2008-07-09 2010-01-14 Micropoint Bioscience Inc Analytical cartridge with fluid flow control
JP5415538B2 (ja) 2008-07-16 2014-02-12 チルドレンズ メディカル センター コーポレーション マイクロチャネルを有する臓器模倣装置ならびにその使用および製造方法
DK2352815T3 (en) * 2008-12-04 2016-05-17 Inserm Inst Nat De La Santé Et De La Rech Médicale Process for producing platelets
WO2010123594A2 (en) * 2009-01-15 2010-10-28 Children's Medical Center Corporation Device for filtration of fluids there through and accompanying method
WO2010123595A2 (en) 2009-01-15 2010-10-28 Mayo Foundation For Medical Education And Research Optical edge connector
US9446360B2 (en) 2009-05-07 2016-09-20 Universite De Strasbourg Microfluidic system and methods for highly selective droplet fusion
US20110000823A1 (en) * 2009-07-01 2011-01-06 Feras Hamad Membrane desulfurization of liquid hydrocarbons using an extractive liquid membrane contactor system and method
US8306304B2 (en) 2009-08-31 2012-11-06 Siemens Aktiengesellschaft Precise image reconstruction of spiral CT images at optional pitch values
US8483351B2 (en) 2009-10-28 2013-07-09 Virginia Tech Intellectual Properties, Inc. Cardiac computed tomography methods and systems using fast exact/quasi-exact filtered back projection algorithms
DE102009051384A1 (de) 2009-10-30 2011-05-12 Friedrich-Alexander-Universität Erlangen-Nürnberg Strahlaufhärtungskorrektur für CT-Perfusionsmessungen
CN102058399B (zh) * 2009-11-18 2012-05-30 中国科学院化学研究所 一种基于微流控芯片的仿生号脉系统
EP3498818A1 (en) * 2011-02-28 2019-06-19 President and Fellows of Harvard College Cell culture system
US9803164B2 (en) 2011-03-18 2017-10-31 New York Blood Center, Inc. Megakaryocyte and platelet production from stem cells
WO2012129109A2 (en) * 2011-03-18 2012-09-27 New York Blood Center, Inc. Megakaryocyte and platelet production from stem cells
JP2012235749A (ja) 2011-05-12 2012-12-06 National Institute Of Advanced Industrial Science & Technology マイクロチップの製造方法、物理マスク、及びマイクロチップ
JP6108426B2 (ja) 2011-06-28 2017-04-05 国立大学法人名古屋大学 血小板産生方法及び血小板産生装置
US9599613B2 (en) 2011-07-20 2017-03-21 University Of Washington Through Its Center For Commercialization Photonic blood typing
US9081003B2 (en) * 2012-05-03 2015-07-14 Purdue Research Foundation Systems and methods for testing drugs and drug delivery systems
CN102698672B (zh) 2012-05-21 2014-01-29 中南大学 一种微流体反应器
JP6429794B2 (ja) 2013-01-03 2018-11-28 ブリガム・アンド・ウイミンズ・ホスピタル・インコーポレイテッド バイオミメティック流体プロセスの系および方法
US9909102B2 (en) 2013-11-19 2018-03-06 Platod Fluidic device for producing platelets
US10590373B2 (en) * 2014-03-31 2020-03-17 Brigham And Women's Hospital, Inc. Systems and methods for biomimetic fluid processing
JP6859351B2 (ja) * 2015-09-08 2021-04-14 ブリガム・アンド・ウイミンズ・ホスピタル・インコーポレイテッド 血小板を産生するためのシステムおよび方法
US20200017812A1 (en) * 2017-03-07 2020-01-16 Platelet Biogenesis, Inc. Recirculating Bioreactor

Also Published As

Publication number Publication date
CA2896997A1 (en) 2014-07-10
AU2013371589A1 (en) 2015-07-23
EP2941642A4 (en) 2016-10-05
CN105308452A (zh) 2016-02-03
EP2941642B1 (en) 2020-05-13
US20230009208A1 (en) 2023-01-12
EP2941642A1 (en) 2015-11-11
US11396016B2 (en) 2022-07-26
US20190283027A1 (en) 2019-09-19
US20150336095A1 (en) 2015-11-26
US10710073B2 (en) 2020-07-14
US20200316597A1 (en) 2020-10-08
CN105308452B (zh) 2018-02-06
US20180021780A1 (en) 2018-01-25
US11850589B2 (en) 2023-12-26
JP2016510212A (ja) 2016-04-07
CA2896997C (en) 2023-10-03
JP6429794B2 (ja) 2018-11-28
AU2013371589C1 (en) 2020-09-24
US9795965B2 (en) 2017-10-24
WO2014107240A1 (en) 2014-07-10
EP3712612A1 (en) 2020-09-23
AU2013371589B2 (en) 2019-11-28
US10343163B2 (en) 2019-07-09

Similar Documents

Publication Publication Date Title
IL279077B (en) System and method for determining location
HK1218958A1 (zh) 仿生流體處理的系統和方法
HK1223896A1 (zh) 訂單處理系統與方法
GB2517503B (en) A speech processing system and method
HK1225414B (zh) 傳感的方法和系統
PL3038799T3 (pl) Sposób i system do oceny co najmniej jednej właściwości manipulatora
EP2972089A4 (en) SYSTEM AND METHOD FOR DETERMINING AND MAINTAINING AN OBJECT AND STATUS
KR102246213B9 (ko) 고온 에칭액을 제공하는 처리 시스템 및 방법
HK1224256A1 (zh) 物體檢測系統以及用於操作物體檢測系統的方法
EP2962092A4 (en) METHODS AND SYSTEMS FOR ENHANCED MICRO-FLUIDIC TREATMENT
ZA201704973B (en) System and method for processing a hydrocarbon-comprising fluid
EP2954406A4 (en) COMMAND PROCESSING SYSTEM AND METHOD
HK1221536A1 (zh) 用於識別人臉的方法和系統
PL3003668T3 (pl) Układ i sposób przetwarzania tworzywa sztucznego
PL3110149T3 (pl) System i sposób renderowania w oparciu o obraz głębi
HK1221056A1 (zh) 用於確定次佳出價的方法和系統
PL3071918T3 (pl) Sposób ograniczenia kierunku i system do ograniczenia kierunku
DK2778921T3 (en) A method and a system for distributed processing of a dataset
ZA201608151B (en) System and method for inspecting a body
HK1217798A1 (zh) 捲筒紙加工系統及用於加工基底捲筒紙的方法
GB201312218D0 (en) A method and system for processing data
PL2994902T3 (pl) Układ i sposób sterowania układu
GB201308484D0 (en) Workpiece handling system and method
EP2965156A4 (en) SYSTEM AND METHOD FOR MANAGING INDUSTRIAL PROCESSES
GB201316429D0 (en) A system and method for co-ordering