HK1217697A1 - 四氫咪唑並 氧氮雜卓衍生物 - Google Patents
四氫咪唑並 氧氮雜卓衍生物Info
- Publication number
- HK1217697A1 HK1217697A1 HK16105614.7A HK16105614A HK1217697A1 HK 1217697 A1 HK1217697 A1 HK 1217697A1 HK 16105614 A HK16105614 A HK 16105614A HK 1217697 A1 HK1217697 A1 HK 1217697A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- oxazepine
- tetrahydroimidazo
- Prior art date
Links
- FBTZTHLFUZVXGB-UHFFFAOYSA-N 1,2,3,5,6,8-hexahydroimidazo[1,5-d][1,4]oxazepine Chemical compound C1OCCN2CNCC2=C1 FBTZTHLFUZVXGB-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361770469P | 2013-02-28 | 2013-02-28 | |
| PCT/JP2014/054724 WO2014133022A1 (ja) | 2013-02-28 | 2014-02-26 | テトラヒドロイミダゾ［１，５－ｄ］［１，４］オキサゼピン誘導体 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1217697A1 true HK1217697A1 (zh) | 2017-01-20 |
Family
ID=51388759
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK16105614.7A HK1217697A1 (zh) | 2013-02-28 | 2016-05-16 | 四氫咪唑並 氧氮雜卓衍生物 |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US9458176B2 (zh) |
| EP (1) | EP2963043B1 (zh) |
| JP (1) | JP5654715B1 (zh) |
| KR (1) | KR102190597B1 (zh) |
| CN (1) | CN105008375B (zh) |
| AR (1) | AR094887A1 (zh) |
| AU (1) | AU2014221775B2 (zh) |
| BR (1) | BR112015020545A2 (zh) |
| CA (1) | CA2901168C (zh) |
| CL (1) | CL2015002391A1 (zh) |
| CY (1) | CY1121231T1 (zh) |
| DK (1) | DK2963043T3 (zh) |
| ES (1) | ES2685025T3 (zh) |
| HK (1) | HK1217697A1 (zh) |
| HR (1) | HRP20181349T1 (zh) |
| HU (1) | HUE040219T2 (zh) |
| IL (1) | IL240402A (zh) |
| LT (1) | LT2963043T (zh) |
| MX (1) | MX362920B (zh) |
| PE (1) | PE20151651A1 (zh) |
| PH (1) | PH12015501878A1 (zh) |
| PL (1) | PL2963043T3 (zh) |
| PT (1) | PT2963043T (zh) |
| RS (1) | RS57602B1 (zh) |
| RU (1) | RU2659219C2 (zh) |
| SG (1) | SG11201505252VA (zh) |
| SI (1) | SI2963043T1 (zh) |
| TW (1) | TWI622592B (zh) |
| UA (1) | UA114950C2 (zh) |
| WO (1) | WO2014133022A1 (zh) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3444363B1 (en) | 2011-06-03 | 2020-11-25 | Eisai R&D Management Co., Ltd. | Biomarkers for prediciting and assessing responsiveness of thyroid and kidney cancer subjects to lenvatinib compounds |
| SG11201402660YA (en) | 2011-12-21 | 2014-10-30 | Novira Therapeutics Inc | Hepatitis b antiviral agents |
| KR102122244B1 (ko) | 2012-08-28 | 2020-06-15 | 얀센 사이언시즈 아일랜드 언리미티드 컴퍼니 | 설파모일-아릴아미드 및 b형 간염 치료제로서의 그 용도 |
| AU2014222641B2 (en) | 2013-02-28 | 2018-03-15 | Janssen Sciences Ireland Uc | Sulfamoyl-arylamides and the use thereof as medicaments for the treatment of Hepatitis B |
| MX353412B (es) | 2013-04-03 | 2018-01-10 | Janssen Sciences Ireland Uc | Derivados de n-fenil-carboxamida y su uso como medicamentos para el tratamiento de la hepatitis b. |
| ES2687968T3 (es) | 2013-05-14 | 2018-10-30 | Eisai R&D Management Co., Ltd. | Biomarcadores para pronosticar y evaluar la reactividad de sujetos con cáncer de endometrio a compuestos con lenvatinib |
| AU2014267235B2 (en) | 2013-05-17 | 2017-10-05 | Janssen Sciences Ireland Uc | Sulphamoylthiophenamide derivatives and the use thereof as medicaments for the treatment of hepatitis B |
| JO3603B1 (ar) | 2013-05-17 | 2020-07-05 | Janssen Sciences Ireland Uc | مشتقات سلفامويل بيرولاميد واستخدامها كادوية لمعالجة التهاب الكبد نوع بي |
| CN108047115B (zh) | 2013-07-25 | 2021-06-29 | 爱尔兰詹森科学公司 | 经乙醛酰胺取代的吡咯酰胺衍生物及其作为药物用于治疗乙型肝炎的用途 |
| EA034448B1 (ru) | 2013-10-23 | 2020-02-10 | Янссен Сайенсиз Айрлэнд Юси | Производные карбоксамида и их применение в качестве медикаментов для лечения гепатита b |
| US10392349B2 (en) | 2014-01-16 | 2019-08-27 | Novira Therapeutics, Inc. | Azepane derivatives and methods of treating hepatitis B infections |
| US9169212B2 (en) | 2014-01-16 | 2015-10-27 | Novira Therapeutics, Inc. | Azepane derivatives and methods of treating hepatitis B infections |
| KR20160128305A (ko) | 2014-02-05 | 2016-11-07 | 노비라 테라퓨틱스, 인코포레이티드 | Hbv 감염의 치료를 위한 병용 요법 |
| US11078193B2 (en) | 2014-02-06 | 2021-08-03 | Janssen Sciences Ireland Uc | Sulphamoylpyrrolamide derivatives and the use thereof as medicaments for the treatment of hepatitis B |
| JP2017206438A (ja) * | 2014-08-22 | 2017-11-24 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | テトラヒドロイミダゾ［１，５−ｄ］［１，４］オキサゼピン化合物（ＴＥＴＲＡＨＹＤＲＯＩＭＩＤＡＺＯ［１，５−ｄ］［１，４］ＯＸＡＺＥＰＩＮＥＣＯＭＰＯＵＮＤ） |
| WO2016033190A1 (en) * | 2014-08-27 | 2016-03-03 | Eisai, Inc. | Radiotracer compounds |
| BR112017002827B1 (pt) | 2014-08-28 | 2023-04-18 | Eisai R&D Management Co., Ltd | Derivado de quinolina altamente puro e método para produção do mesmo |
| MX2017010474A (es) | 2015-02-25 | 2017-11-28 | Eisai R&D Man Co Ltd | Metodo para suprimir el amargor de un derivado de quinoleina. |
| KR20240064733A (ko) | 2015-03-04 | 2024-05-13 | 머크 샤프 앤드 돔 코포레이션 | 암을 치료하기 위한 pd-1 길항제 및 vegfr/fgfr/ret 티로신 키나제 억제제의 조합 |
| US9884831B2 (en) | 2015-03-19 | 2018-02-06 | Novira Therapeutics, Inc. | Azocane and azonane derivatives and methods of treating hepatitis B infections |
| SG11201710198YA (en) | 2015-06-16 | 2018-01-30 | Eisai R&D Man Co Ltd | Anticancer agent |
| US10875876B2 (en) | 2015-07-02 | 2020-12-29 | Janssen Sciences Ireland Uc | Cyclized sulfamoylarylamide derivatives and the use thereof as medicaments for the treatment of hepatitis B |
| CN108430971A (zh) | 2015-09-29 | 2018-08-21 | 诺维拉治疗公司 | 乙型肝炎抗病毒剂的晶体形式 |
| AU2017248828A1 (en) | 2016-04-15 | 2018-11-01 | Janssen Sciences Ireland Uc | Combinations and methods comprising a capsid assembly inhibitor |
| KR102515694B1 (ko) | 2017-01-10 | 2023-03-29 | 바이엘 악티엔게젤샤프트 | 해충 방제제로서의 헤테로사이클 유도체 |
| WO2018130443A1 (de) | 2017-01-10 | 2018-07-19 | Bayer Aktiengesellschaft | Heterocyclen-derivate als schädlingsbekämpfungsmittel |
| JP2021035911A (ja) * | 2017-11-15 | 2021-03-04 | 大日本住友製薬株式会社 | 縮環ピラゾール誘導体及びその医薬用途 |
| KR102688238B1 (ko) | 2017-11-24 | 2024-07-25 | 스미토모 파마 가부시키가이샤 | 6, 7-디히드로 피라졸로[1, 5-a]피라지논 유도체 및 그 의약 용도 |
| CN111867582A (zh) | 2018-03-14 | 2020-10-30 | 爱尔兰詹森科学公司 | 衣壳组装调节剂给药方案 |
| TWI820231B (zh) | 2018-10-11 | 2023-11-01 | 德商拜耳廠股份有限公司 | 用於製備經取代咪唑衍生物之方法 |
| CA3127152A1 (en) | 2019-02-22 | 2020-08-27 | Janssen Sciences Ireland Unlimited Company | Amide derivatives useful in the treatment of hbv infection or hbv-induced diseases |
| CA3132554A1 (en) | 2019-05-06 | 2020-11-12 | Bart Rudolf Romanie Kesteleyn | Amide derivatives useful in the treatment of hbv infection or hbv-induced diseases |
| US11155547B1 (en) * | 2020-06-18 | 2021-10-26 | Alterity Therapeutics Limited | Compounds for and methods of treating diseases |
| US20230247994A1 (en) | 2020-07-02 | 2023-08-10 | Bayer Aktiengesellschaft | Heterocyclene derivatives as pest control agents |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL158021A0 (en) * | 2001-04-12 | 2004-03-28 | Hoffmann La Roche | DIHYDRO-BENZO [b] [1,4] DIAZEPIN-2-ONE DERIVATIVES AS MGLUR2 ANTAGONIST I |
| ATE460417T1 (de) * | 2005-03-23 | 2010-03-15 | Hoffmann La Roche | Acetylenylpyrazolopyrimidinderivate als mglur2- antagonsten |
| AU2006298829B2 (en) * | 2005-09-27 | 2011-03-03 | F. Hoffmann-La Roche Ag | Oxadiazolyl pyrazolo-pyrimidines as mGluR2 antagonists |
| JP2009184924A (ja) | 2006-05-31 | 2009-08-20 | Eisai R & D Management Co Ltd | 生物学的試薬用化合物 |
| CA2657835C (en) | 2008-03-07 | 2017-09-19 | Mathieu Audet | Documents discrimination system and method thereof |
| JP5690277B2 (ja) * | 2008-11-28 | 2015-03-25 | ジャンセン ファーマシューティカルズ， インコーポレイテッド． | 代謝型グルタミン酸受容体の調節因子としてのインドールおよびベンゾオキサジン誘導体 |
| WO2010068520A2 (en) * | 2008-12-11 | 2010-06-17 | Cara Therapeutics, Inc. | Substituted imidazoheterocycle derivatives |
| WO2010075203A1 (en) | 2008-12-22 | 2010-07-01 | Schering Corporation | Gamma secretase modulators |
-
2014
- 2014-02-26 CA CA2901168A patent/CA2901168C/en active Active
- 2014-02-26 EP EP14756740.8A patent/EP2963043B1/en active Active
- 2014-02-26 MX MX2015010741A patent/MX362920B/es active IP Right Grant
- 2014-02-26 TW TW103106584A patent/TWI622592B/zh not_active IP Right Cessation
- 2014-02-26 SG SG11201505252VA patent/SG11201505252VA/en unknown
- 2014-02-26 WO PCT/JP2014/054724 patent/WO2014133022A1/ja active Application Filing
- 2014-02-26 HU HUE14756740A patent/HUE040219T2/hu unknown
- 2014-02-26 PE PE2015001791A patent/PE20151651A1/es unknown
- 2014-02-26 KR KR1020157022943A patent/KR102190597B1/ko active IP Right Grant
- 2014-02-26 US US14/190,356 patent/US9458176B2/en active Active
- 2014-02-26 RS RS20180992A patent/RS57602B1/sr unknown
- 2014-02-26 PT PT14756740T patent/PT2963043T/pt unknown
- 2014-02-26 UA UAA201508269A patent/UA114950C2/uk unknown
- 2014-02-26 RU RU2015135967A patent/RU2659219C2/ru active
- 2014-02-26 AU AU2014221775A patent/AU2014221775B2/en not_active Ceased
- 2014-02-26 DK DK14756740.8T patent/DK2963043T3/en active
- 2014-02-26 JP JP2014541469A patent/JP5654715B1/ja active Active
- 2014-02-26 BR BR112015020545A patent/BR112015020545A2/pt active Search and Examination
- 2014-02-26 ES ES14756740.8T patent/ES2685025T3/es active Active
- 2014-02-26 SI SI201430830T patent/SI2963043T1/sl unknown
- 2014-02-26 PL PL14756740T patent/PL2963043T3/pl unknown
- 2014-02-26 LT LTEP14756740.8T patent/LT2963043T/lt unknown
- 2014-02-26 CN CN201480009750.3A patent/CN105008375B/zh not_active Expired - Fee Related
- 2014-02-26 AR ARP140100595A patent/AR094887A1/es unknown
-
2015
- 2015-08-06 IL IL240402A patent/IL240402A/en active IP Right Grant
- 2015-08-26 CL CL2015002391A patent/CL2015002391A1/es unknown
- 2015-08-26 PH PH12015501878A patent/PH12015501878A1/en unknown
-
2016
- 2016-05-16 HK HK16105614.7A patent/HK1217697A1/zh not_active IP Right Cessation
-
2018
- 2018-08-23 CY CY20181100881T patent/CY1121231T1/el unknown
- 2018-08-23 HR HRP20181349TT patent/HRP20181349T1/hr unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20230226 |