SG10201610251PA
(en)
|
2012-06-08 |
2017-01-27 |
Aduro Biotech |
Compositions and methods for cancer immunotherapy
|
SG10201704611WA
(en)
|
2012-12-13 |
2017-07-28 |
Aduro Biotech Inc |
Compositions comprising cyclic purine dinucleotides having defined stereochemistries and methods for their preparation and use
|
BR112015027327B1
(pt)
|
2013-04-29 |
2022-08-02 |
Rutgers, The State University Of New Jersey |
Composto, modulador de cgas, composição farmacêutica compreendendo o referido composto ou modulador
|
CN105377867B
(zh)
|
2013-05-03 |
2019-11-12 |
加利福尼亚大学董事会 |
I型干扰素的环状二核苷酸诱导
|
AU2014268836B2
(en)
|
2013-05-18 |
2018-08-02 |
Aduro Biotech, Inc. |
Compositions and methods for activating "stimulator of interferon gene"-dependent signalling
|
US9549944B2
(en)
|
2013-05-18 |
2017-01-24 |
Aduro Biotech, Inc. |
Compositions and methods for inhibiting “stimulator of interferon gene”—dependent signalling
|
WO2015017652A1
(en)
|
2013-07-31 |
2015-02-05 |
Memorial Sloan-Kettering Cancer Center |
Sting crystals and modulators
|
MA41044A
(fr)
|
2014-10-08 |
2017-08-15 |
Novartis Ag |
Compositions et procédés d'utilisation pour une réponse immunitaire accrue et traitement contre le cancer
|
CU20170052A7
(es)
|
2014-10-14 |
2017-11-07 |
Dana Farber Cancer Inst Inc |
Moléculas de anticuerpo que se unen a pd-l1
|
MY190404A
(en)
|
2015-03-10 |
2022-04-21 |
Aduro Biotech Inc |
Compositions and methods for activating "stimulator of interferon gene"-dependent signalling
|
EP3316902A1
(en)
|
2015-07-29 |
2018-05-09 |
Novartis AG |
Combination therapies comprising antibody molecules to tim-3
|
SI3317301T1
(sl)
|
2015-07-29 |
2021-10-29 |
Novartis Ag |
Kombinirane terapije, ki obsegajo molekule protitelesa na LAG-3
|
US11453697B1
(en)
|
2015-08-13 |
2022-09-27 |
Merck Sharp & Dohme Llc |
Cyclic di-nucleotide compounds as sting agonists
|
BR112018002757A8
(pt)
|
2015-08-13 |
2023-04-11 |
Merck Sharp & Dohme |
Composto, composição farmacêutica, e, métodos para induzir uma resposta imune, para induzir uma produção de interferon tipo i e para tratamento de um distúrbio
|
CN105367617A
(zh)
*
|
2015-09-25 |
2016-03-02 |
武汉品生科技有限公司 |
一种基于环二腺核苷酸的衍生物、tat多肽及其在一型干扰素小分子中抑制剂的应用
|
CN106554416B
(zh)
*
|
2015-12-09 |
2019-03-15 |
聊城市奥润生物医药科技有限公司 |
一种抗pd-l1人源化单克隆抗体联合干扰素基因刺激蛋白(sting)激动剂在抗肿瘤中的应用
|
US20180369268A1
(en)
*
|
2015-12-16 |
2018-12-27 |
Aduro Biotech, Inc. |
Methods for identifying inhibitors of "stimulator of interferon gene"- dependent interferon production
|
CA3007671A1
(en)
|
2015-12-17 |
2017-06-22 |
Novartis Ag |
Antibody molecules to pd-1 and uses thereof
|
KR20180100224A
(ko)
|
2016-01-11 |
2018-09-07 |
노바르티스 아게 |
인간 인터루킨-2에 대한 면역-자극 인간화 단일클론 항체, 및 이의 융합 단백질
|
HRP20221263T1
(hr)
*
|
2016-03-18 |
2023-03-03 |
Immune Sensor, Llc |
Ciklički di-nukleotidni spojevi i postupci uporabe
|
EP3507367A4
(en)
|
2016-07-05 |
2020-03-25 |
Aduro BioTech, Inc. |
CYCLIC DINUCLEOTID COMPOUNDS WITH INCLUDED NUCLEIC ACIDS AND USES THEREOF
|
DE102016113714A1
(de)
|
2016-07-26 |
2018-02-01 |
Rosa Karl |
Transfektionsverfahren mit nicht-viralen Genliefersystemen
|
TN2020000159A1
(en)
|
2016-10-04 |
2022-04-04 |
Merck Sharp & Dohme |
BENZO[b]THIOPHENE COMPOUNDS AS STING AGONISTS
|
JOP20170192A1
(ar)
|
2016-12-01 |
2019-01-30 |
Takeda Pharmaceuticals Co |
داي نوكليوتيد حلقي
|
AU2017378783A1
(en)
*
|
2016-12-20 |
2019-07-04 |
Merck Sharp & Dohme Corp. |
Cyclic dinucleotide sting agonists for cancer treatment
|
US11492367B2
(en)
|
2017-01-27 |
2022-11-08 |
Janssen Biotech, Inc. |
Cyclic dinucleotides as sting agonists
|
US11021511B2
(en)
|
2017-01-27 |
2021-06-01 |
Janssen Biotech, Inc. |
Cyclic dinucleotides as sting agonists
|
KR20190110612A
(ko)
|
2017-02-01 |
2019-09-30 |
모더나티엑스, 인크. |
활성화 종양유전자 돌연변이 펩티드를 인코드하는 면역조절 치료 mrna 조성물
|
US10933078B2
(en)
|
2017-02-21 |
2021-03-02 |
Board Of Regents, The University Of Texas System |
Cyclic dinucleotides as agonists of stimulator of interferon gene dependent signalling
|
EP3621624B1
(en)
|
2017-05-12 |
2023-08-30 |
Merck Sharp & Dohme LLC |
Cyclic di-nucleotide compounds as sting agonists
|
WO2018229715A1
(en)
|
2017-06-16 |
2018-12-20 |
Novartis Ag |
Compositions comprising anti-cd32b antibodies and methods of use thereof
|
WO2018237173A1
(en)
|
2017-06-22 |
2018-12-27 |
Novartis Ag |
ANTIBODY MOLECULES DIRECTED AGAINST CD73 AND CORRESPONDING USES
|
JP7433910B2
(ja)
|
2017-06-22 |
2024-02-20 |
ノバルティス アーゲー |
Cd73に対する抗体分子及びその使用
|
JP2020530838A
(ja)
|
2017-08-04 |
2020-10-29 |
メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. |
がん治療のためのベンゾ[b]チオフェンSTINGアゴニスト
|
AU2018311965A1
(en)
|
2017-08-04 |
2020-02-13 |
Merck Sharp & Dohme Llc |
Combinations of PD-1 antagonists and benzo[b]thiophene sting antagonists for cancer treatment
|
EP3675859A4
(en)
|
2017-08-31 |
2021-06-30 |
Sperovie Biosciences, Inc. |
COMPOUNDS, COMPOSITIONS AND PROCEDURES FOR TREATMENT OF DISEASES
|
CN111051328B
(zh)
*
|
2017-08-31 |
2023-11-03 |
百时美施贵宝公司 |
作为抗癌剂的环二核苷酸
|
EP3676278B1
(en)
*
|
2017-08-31 |
2023-04-12 |
Bristol-Myers Squibb Company |
Cyclic dinucleotides as anticancer agents
|
WO2019079261A1
(en)
*
|
2017-10-16 |
2019-04-25 |
Bristol-Myers Squibb Company |
CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS
|
WO2019081983A1
(en)
|
2017-10-25 |
2019-05-02 |
Novartis Ag |
CD32B TARGETING ANTIBODIES AND METHODS OF USE
|
AU2018364708A1
(en)
|
2017-11-10 |
2020-05-21 |
Takeda Pharmaceutical Company Limited |
Sting modulator compounds, and methods of making and using
|
US11685761B2
(en)
|
2017-12-20 |
2023-06-27 |
Merck Sharp & Dohme Llc |
Cyclic di-nucleotide compounds as sting agonists
|
US10966999B2
(en)
|
2017-12-20 |
2021-04-06 |
Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. |
3′3′ cyclic dinucleotides with phosphonate bond activating the sting adaptor protein
|
AU2018392212B9
(en)
|
2017-12-20 |
2021-03-18 |
Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. |
2'3' cyclic dinucleotides with phosphonate bond activating the STING adaptor protein
|
IL277344B1
(en)
|
2018-03-23 |
2024-01-01 |
Codiak Biosciences Inc |
Extracellular vesicles that include agonist-STING
|
WO2019195063A1
(en)
|
2018-04-03 |
2019-10-10 |
Merck Sharp & Dohme Corp. |
Aza-benzothiophene compounds as sting agonists
|
CN111971277B
(zh)
|
2018-04-03 |
2023-06-06 |
默沙东有限责任公司 |
作为sting激动剂的苯并噻吩及相关化合物
|
TWI818007B
(zh)
|
2018-04-06 |
2023-10-11 |
捷克科學院有機化學與生物化學研究所 |
2'3'-環二核苷酸
|
WO2019193543A1
(en)
|
2018-04-06 |
2019-10-10 |
Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. |
3'3'-cyclic dinucleotides
|
US20210214459A1
(en)
|
2018-05-31 |
2021-07-15 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
BR112021003472A2
(pt)
|
2018-09-06 |
2021-05-18 |
Daiichi Sankyo Company, Limited |
derivado de dinucleotídeo cíclico e conjugado de anticorpo-fármaco do mesmo
|
CN110938104A
(zh)
|
2018-09-21 |
2020-03-31 |
上海迪诺医药科技有限公司 |
环状二核苷酸类似物、其药物组合物及应用
|
US20220168415A1
(en)
|
2019-03-21 |
2022-06-02 |
Codiak Biosciences, Inc. |
Extracellular vesicles for vaccine delivery
|
SG11202109587TA
(en)
|
2019-03-21 |
2021-10-28 |
Codiak Biosciences Inc |
Extracellular vesicle conjugates and uses thereof
|
WO2020205688A1
(en)
|
2019-04-04 |
2020-10-08 |
Merck Sharp & Dohme Corp. |
Inhibitors of histone deacetylase-3 useful for the treatment of cancer, inflammation, neurodegeneration diseases and diabetes
|
CN114127082A
(zh)
|
2019-05-09 |
2022-03-01 |
阿里戈斯治疗公司 |
作为sting调节剂的经修饰的环状二核苷化合物
|
US20230181758A1
(en)
|
2019-07-03 |
2023-06-15 |
Codiak Biosciences, Inc. |
Extracellular vesicles targeting dendritic cells and uses thereof
|
WO2021003445A1
(en)
|
2019-07-03 |
2021-01-07 |
Codiak Biosciences, Inc. |
Extracellular vesicles targeting t cells and uses thereof
|
CA3145889A1
(en)
|
2019-07-05 |
2021-01-14 |
Tambo, Inc. |
Trans-cyclooctene bioorthogonal agents and uses in cancer and immunotherapy
|
US11155567B2
(en)
|
2019-08-02 |
2021-10-26 |
Mersana Therapeutics, Inc. |
Sting agonist compounds and methods of use
|
US20230103726A1
(en)
|
2019-09-25 |
2023-04-06 |
Codiak Biosciences, Inc. |
Methods of producing extracellular vesicles
|
AU2020355240A1
(en)
|
2019-09-25 |
2022-04-21 |
Lonza Sales Ag |
Extracellular vesicle compositions
|
US20230241089A1
(en)
|
2019-09-25 |
2023-08-03 |
Codiak Biosciences, Inc. |
Sting agonist comprising exosomes for treating neuroimmunological disorders
|
EP4034150A1
(en)
|
2019-09-25 |
2022-08-03 |
Codiak BioSciences, Inc. |
Sting agonist comprising exosomes combined with il-12 displaying exosomes for treating a tumour
|
EP4069683A1
(en)
|
2019-12-06 |
2022-10-12 |
Mersana Therapeutics, Inc. |
Dimeric compounds as sting agonists
|
CN115209921A
(zh)
|
2020-03-06 |
2022-10-18 |
第一三共株式会社 |
包含新型环状二核苷酸衍生物的抗体药物偶联物
|
EP4117717A1
(en)
|
2020-03-13 |
2023-01-18 |
Codiak BioSciences, Inc. |
Extracellular vesicles for treating neurological disorders
|
WO2021189047A2
(en)
|
2020-03-20 |
2021-09-23 |
Codiak Biosciences, Inc. |
Extracellular vesicles for therapy
|
WO2021206158A1
(ja)
|
2020-04-10 |
2021-10-14 |
小野薬品工業株式会社 |
がん治療方法
|
CN115803032A
(zh)
|
2020-05-15 |
2023-03-14 |
免疫传感器治疗股份有限公司 |
Sting激动剂与免疫检查点抑制剂的联合治疗
|
WO2021237100A1
(en)
|
2020-05-21 |
2021-11-25 |
Codiak Biosciences, Inc. |
Methods of targeting extracellular vesicles to lung
|
WO2022032191A1
(en)
|
2020-08-07 |
2022-02-10 |
Tambo, Inc. |
Trans-cyclooctene bioorthogonal agents and uses in cancer and immunotherapy
|
JPWO2022050300A1
(zh)
|
2020-09-02 |
2022-03-10 |
|
|
WO2022066883A1
(en)
|
2020-09-23 |
2022-03-31 |
Codiak Biosciences, Inc. |
Extracellular vesicles comprising kras antigens and uses thereof
|
CA3192470A1
(en)
|
2020-09-23 |
2022-03-31 |
Tim SOOS |
Methods of producing extracellular vesicles
|
WO2022079175A1
(en)
|
2020-10-14 |
2022-04-21 |
Boehringer Ingelheim International Gmbh |
Combination of a sting agonist and a complex comprising a cell penetrating peptide, a cargo and a tlr peptide agonist
|
KR20230107586A
(ko)
*
|
2020-10-20 |
2023-07-17 |
타이리간드 바이오사이언스 (상하이) 리미티드 |
다기능성 사이클릭 디뉴클레오티드 및 이의 용도
|
WO2022097117A1
(en)
|
2020-11-09 |
2022-05-12 |
Takeda Pharmaceutical Company Ltd. |
Antibody drug conjugates
|
TW202241454A
(zh)
|
2021-02-01 |
2022-11-01 |
日商第一三共股份有限公司 |
抗體-免疫賦活化劑共軛物之新穎製造方法
|
AU2022315305A1
(en)
|
2021-07-23 |
2024-02-01 |
Immunesensor Therapeutics, Inc. |
Sting agonist combination treatments with cytokines
|
WO2023056468A1
(en)
|
2021-09-30 |
2023-04-06 |
Codiak Biosciences, Inc. |
Extracellular vesicle comprising cholesterol tagged sting-agonist
|
WO2023154799A1
(en)
|
2022-02-14 |
2023-08-17 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Combination immunotherapy for treating cancer
|