HK1215282A1 - 抗豬生殖與呼吸綜合征病毒的動物 - Google Patents

抗豬生殖與呼吸綜合征病毒的動物

Info

Publication number
HK1215282A1
HK1215282A1 HK16103259.2A HK16103259A HK1215282A1 HK 1215282 A1 HK1215282 A1 HK 1215282A1 HK 16103259 A HK16103259 A HK 16103259A HK 1215282 A1 HK1215282 A1 HK 1215282A1
Authority
HK
Hong Kong
Prior art keywords
respiratory syndrome
syndrome virus
porcine reproductive
virus resistant
resistant animals
Prior art date
Application number
HK16103259.2A
Other languages
English (en)
Inventor
Randall S Prather
Kevin Wells
Kristin Whitworth
Original Assignee
Univ Missouri
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Missouri filed Critical Univ Missouri
Publication of HK1215282A1 publication Critical patent/HK1215282A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • A01K67/0276—Knock-out vertebrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/07—Animals genetically altered by homologous recombination
    • A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/15—Animals comprising multiple alterations of the genome, by transgenesis or homologous recombination, e.g. obtained by cross-breeding
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/108—Swine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/02—Animal zootechnically ameliorated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/7056—Lectin superfamily, e.g. CD23, CD72
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00—Nucleic acids vectors
    • C12N2800/80—Vectors containing sites for inducing double-stranded breaks, e.g. meganuclease restriction sites

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Animal Husbandry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK16103259.2A 2011-05-16 2016-03-21 抗豬生殖與呼吸綜合征病毒的動物 HK1215282A1 (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161519076P 2011-05-16 2011-05-16

Publications (1)

Publication Number Publication Date
HK1215282A1 true HK1215282A1 (zh) 2016-08-19

Family

ID=47177326

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16103259.2A HK1215282A1 (zh) 2011-05-16 2016-03-21 抗豬生殖與呼吸綜合征病毒的動物

Country Status (21)

Country Link
US (5) US9820475B2 (zh)
EP (2) EP2709445B1 (zh)
JP (5) JP2014519323A (zh)
KR (5) KR102627319B1 (zh)
CN (3) CN105112450A (zh)
AU (5) AU2012255744A1 (zh)
BR (1) BR112013029498A8 (zh)
CA (2) CA3184311A1 (zh)
CY (1) CY1120890T1 (zh)
DK (1) DK2709445T3 (zh)
ES (1) ES2691618T3 (zh)
HK (1) HK1215282A1 (zh)
HR (1) HRP20181729T1 (zh)
HU (1) HUE039793T2 (zh)
LT (1) LT2709445T (zh)
MX (1) MX357421B (zh)
PL (1) PL2709445T3 (zh)
PT (1) PT2709445T (zh)
RU (1) RU2644673C2 (zh)
SI (1) SI2709445T1 (zh)
WO (1) WO2012158828A1 (zh)

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KR102627319B1 (ko) * 2011-05-16 2024-01-23 더 큐레이터스 오브 더 유니버시티 오브 미주리 돼지 생식기 호흡기 증후군 바이러스 내성 동물
GB201313235D0 (en) * 2013-07-24 2013-09-04 Univ Edinburgh Antiviral Compositions Methods and Animals
WO2015153647A1 (en) * 2014-03-31 2015-10-08 Mice With Horns, Llc Method of preventing or reducing virus transmission in animals
CN104593422A (zh) * 2015-01-08 2015-05-06 中国农业大学 一种抗蓝耳病克隆猪的制备方法
US11246299B2 (en) * 2015-03-04 2022-02-15 Pormedtec Co., Ltd. Disease model pig exhibiting stable phenotype, and production method thereof
CN109475107A (zh) * 2015-08-06 2019-03-15 密苏里大学管理者 具有修饰的cd163基因的抗病原体动物
KR102495662B1 (ko) * 2015-08-06 2023-02-06 더 큐레이터스 오브 더 유니버시티 오브 미주리 변형된 cd163 유전자를 갖는 병원균-내성 동물
GB201617559D0 (en) 2016-10-17 2016-11-30 University Court Of The University Of Edinburgh The Swine comprising modified cd163 and associated methods
CN107937345B (zh) * 2017-11-16 2019-01-29 山东蓝思种业股份有限公司 一种制备同时敲除cd163基因和cd13基因的猪成纤维细胞的方法
AU2018419649A1 (en) * 2018-04-17 2020-10-22 The Curators Of The University Of Missouri Methods for protecting porcine fetuses from infection with virus
US11160260B2 (en) 2018-04-17 2021-11-02 The Curators Of The University Of Missouri Methods for protecting porcine fetuses from infection with porcine reproductive and respiratory syndrome virus (PRRSV)
AU2019257776A1 (en) * 2018-04-27 2020-10-22 The Curators Of The University Of Missouri Pathogen-resistant animals having modified aminopeptidase N (ANPEP) genes
CN109197780A (zh) * 2018-11-26 2019-01-15 湖北天牧畜禽有限公司 一种减少仔猪生病的养殖方法
WO2021024123A1 (en) * 2019-08-06 2021-02-11 Nzeno Limited Donor pigs for xenotransplantation
CA3179710A1 (en) 2020-05-05 2021-11-11 Andrew Mark CIGAN Methods for improving the health of porcine species by targeted inactivation of cd163
CA3207080A1 (en) * 2021-01-05 2022-07-14 Etsuko Miyagi Biomarker for determining fertility, and determining method using same

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US5945577A (en) 1997-01-10 1999-08-31 University Of Massachusetts As Represented By Its Amherst Campus Cloning using donor nuclei from proliferating somatic cells
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US6740490B2 (en) * 2001-01-29 2004-05-25 Kansas State University Research Foundation Identification and applications of porcine reproductive and respiratory syndrome virus host susceptibility factor(s) for improved swine breeding
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CN109475107A (zh) 2015-08-06 2019-03-15 密苏里大学管理者 具有修饰的cd163基因的抗病原体动物

Also Published As

Publication number Publication date
AU2012255744A1 (en) 2014-01-09
JP6970525B2 (ja) 2021-11-24
MX2013013427A (es) 2014-09-04
KR20240014587A (ko) 2024-02-01
HRP20181729T1 (hr) 2018-12-28
KR20220111739A (ko) 2022-08-09
PL2709445T3 (pl) 2019-01-31
MX357421B (es) 2018-07-09
RU2013155677A (ru) 2015-06-27
US20140096275A1 (en) 2014-04-03
AU2017202540B2 (en) 2018-08-09
CN111593025A (zh) 2020-08-28
EP3420813A1 (en) 2019-01-02
KR102627319B1 (ko) 2024-01-23
LT2709445T (lt) 2018-11-12
KR20230132606A (ko) 2023-09-15
JP2014519323A (ja) 2014-08-14
KR20200063264A (ko) 2020-06-04
US20200137992A1 (en) 2020-05-07
US11019809B2 (en) 2021-06-01
KR102428306B1 (ko) 2022-08-03
EP2709445B1 (en) 2018-10-03
US9820475B2 (en) 2017-11-21
AU2023219858A1 (en) 2023-09-28
EP2709445A1 (en) 2014-03-26
KR20140034229A (ko) 2014-03-19
KR102574897B1 (ko) 2023-09-06
AU2018256670A1 (en) 2018-12-06
CA2836288A1 (en) 2012-11-22
ES2691618T3 (es) 2018-11-28
WO2012158828A1 (en) 2012-11-22
JP2019193660A (ja) 2019-11-07
JP2024069309A (ja) 2024-05-21
BR112013029498A2 (pt) 2016-08-09
SI2709445T1 (sl) 2018-11-30
CN103687482A (zh) 2014-03-26
JP2017158579A (ja) 2017-09-14
PT2709445T (pt) 2018-11-27
HUE039793T2 (hu) 2019-02-28
CN105112450A (zh) 2015-12-02
CY1120890T1 (el) 2019-12-11
BR112013029498A8 (pt) 2017-02-21
US20180027783A1 (en) 2018-02-01
AU2020294305A1 (en) 2021-02-11
EP2709445A4 (en) 2015-03-25
US20180368374A1 (en) 2018-12-27
RU2644673C2 (ru) 2018-02-13
US10405526B2 (en) 2019-09-10
AU2017202540A1 (en) 2017-05-18
CA3184311A1 (en) 2012-11-22
US20210259219A1 (en) 2021-08-26
JP2022081637A (ja) 2022-05-31
US10080353B2 (en) 2018-09-25
AU2018256670B2 (en) 2020-09-24
DK2709445T3 (en) 2018-11-19

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