HK1215179A1 - 促紅細胞生成素表達增強劑 - Google Patents
促紅細胞生成素表達增強劑Info
- Publication number
- HK1215179A1 HK1215179A1 HK16103205.7A HK16103205A HK1215179A1 HK 1215179 A1 HK1215179 A1 HK 1215179A1 HK 16103205 A HK16103205 A HK 16103205A HK 1215179 A1 HK1215179 A1 HK 1215179A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- expression promoter
- erythropoietin expression
- erythropoietin
- promoter
- expression
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012258027 | 2012-11-26 | ||
| PCT/JP2013/006916 WO2014080640A1 (ja) | 2012-11-26 | 2013-11-25 | エリスロポエチン発現増強剤 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1215179A1 true HK1215179A1 (zh) | 2016-08-19 |
Family
ID=50775835
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK16103205.7A HK1215179A1 (zh) | 2012-11-26 | 2016-03-18 | 促紅細胞生成素表達增強劑 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US10004718B2 (zh) |
| EP (1) | EP2923700B1 (zh) |
| JP (1) | JP6284159B2 (zh) |
| CN (1) | CN104936591B (zh) |
| CA (1) | CA2896437C (zh) |
| HK (1) | HK1215179A1 (zh) |
| WO (1) | WO2014080640A1 (zh) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2017031095A (ja) * | 2015-07-31 | 2017-02-09 | 国立大学法人東北大学 | ミトコンドリア局在蛍光化合物 |
| JP6872195B2 (ja) * | 2015-10-29 | 2021-05-19 | 国立大学法人東北大学 | コラーゲン産生抑制剤 |
| WO2017072816A1 (ja) * | 2015-10-29 | 2017-05-04 | 国立大学法人東北大学 | 臓器線維化疾患の治療剤 |
| WO2017072984A1 (ja) * | 2015-10-29 | 2017-05-04 | 株式会社東北テクノアーチ | 筋萎縮性疾患治療剤 |
| JP2017105729A (ja) * | 2015-12-10 | 2017-06-15 | 国立大学法人東北大学 | ミトコンドリア病の治療剤 |
| JP2019038747A (ja) * | 2015-12-10 | 2019-03-14 | 株式会社 東北テクノアーチ | インドール酢酸誘導体 |
| JP2019038746A (ja) * | 2015-12-10 | 2019-03-14 | 株式会社 東北テクノアーチ | ４−フェニル−４−オキソブタン酸誘導体 |
| JP7043784B2 (ja) * | 2016-10-28 | 2022-03-30 | 大正製薬株式会社 | 発毛剤 |
| JP6857346B2 (ja) * | 2016-11-11 | 2021-04-14 | 国立大学法人東北大学 | ライソゾーム病の予防又は改善剤 |
| JP6845565B2 (ja) * | 2017-02-10 | 2021-03-17 | 国立大学法人東北大学 | インドール酢酸アミド誘導体 |
| JP7329784B2 (ja) | 2017-12-27 | 2023-08-21 | 国立大学法人東北大学 | 難聴の予防又は改善剤 |
| US20200397777A1 (en) * | 2018-01-09 | 2020-12-24 | Cornell University | Prevention and treatment of organ fibrosis |
| JP7373804B2 (ja) | 2018-06-05 | 2023-11-06 | 国立大学法人東北大学 | 精子の受精機能増強剤 |
| WO2023238894A1 (ja) * | 2022-06-10 | 2023-12-14 | 国立大学法人東北大学 | 抗ウイルス剤 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA02007289A (es) | 2000-01-28 | 2003-09-22 | Melacure Therapeutics Ab | Agonistas y antagonistas novedosos de receptores de melanocortina. |
| CA2455754A1 (en) | 2001-07-31 | 2003-02-20 | Bayer Healthcare Ag | Amine derivatives |
| CA2541126A1 (en) | 2003-10-03 | 2005-04-21 | Veijlen N.V. | Animal feed composition |
| US9408405B2 (en) | 2003-10-03 | 2016-08-09 | Veijlen N.V. | Use of compounds that are able to increase the serum IGF-1 level for the preparation of a therapeutical composition for treatment of various disease states associated with a reduced IGF-1 serum level in humans and animals |
| WO2010045451A1 (en) | 2008-10-16 | 2010-04-22 | Glaxosmithkline Llc | Pyrrolopyrimidine compounds |
| RU2397975C1 (ru) | 2008-11-27 | 2010-08-27 | Андрей Александрович Иващенко | Замещенные 2-(5-гидрокси-2-метил-1н-индол-3-ил)уксусные кислоты и их эфиры, противовирусное активное начало, фармацевтическая композиция, лекарственное средство, способ лечения вирусных заболеваний |
| US20100160243A1 (en) | 2008-12-24 | 2010-06-24 | National Yang-Ming University | Compounds and methods for enhancing erythropoiesis |
| AU2010271732B2 (en) * | 2009-07-17 | 2016-08-25 | Japan Tobacco Inc. | Triazolopyridine compound, and action thereof as prolyl hydroxylase inhibitor and erythropoietin production inducer |
| JP2011190206A (ja) | 2010-03-15 | 2011-09-29 | Sanwa Kagaku Kenkyusho Co Ltd | 新規インドール誘導体及びその医薬用途 |
| JP2012082181A (ja) | 2010-10-14 | 2012-04-26 | Tohoku Techno Arch Co Ltd | 内因性エリスロポエチン発現増強剤及び有機イオントランスポーター発現増強剤 |
-
2013
- 2013-11-25 WO PCT/JP2013/006916 patent/WO2014080640A1/ja active Application Filing
- 2013-11-25 EP EP13857636.8A patent/EP2923700B1/en active Active
- 2013-11-25 JP JP2014548466A patent/JP6284159B2/ja active Active
- 2013-11-25 CN CN201380071092.6A patent/CN104936591B/zh active Active
- 2013-11-25 CA CA2896437A patent/CA2896437C/en active Active
- 2013-11-25 US US14/646,640 patent/US10004718B2/en active Active
-
2016
- 2016-03-18 HK HK16103205.7A patent/HK1215179A1/zh unknown
-
2018
- 2018-06-25 US US16/017,520 patent/US10463647B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP6284159B2 (ja) | 2018-02-28 |
| US10463647B2 (en) | 2019-11-05 |
| EP2923700A4 (en) | 2016-08-17 |
| US10004718B2 (en) | 2018-06-26 |
| CN104936591A (zh) | 2015-09-23 |
| CA2896437A1 (en) | 2014-05-30 |
| CN104936591B (zh) | 2018-05-29 |
| WO2014080640A1 (ja) | 2014-05-30 |
| JPWO2014080640A1 (ja) | 2017-01-05 |
| US20150353489A1 (en) | 2015-12-10 |
| EP2923700A1 (en) | 2015-09-30 |
| EP2923700B1 (en) | 2018-11-07 |
| US20180353475A1 (en) | 2018-12-13 |
| CA2896437C (en) | 2021-01-19 |
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