HK1214172A1 - 與改善靶向神經系統的藥理學試劑的性質有關的方法和組合物 - Google Patents
與改善靶向神經系統的藥理學試劑的性質有關的方法和組合物Info
- Publication number
- HK1214172A1 HK1214172A1 HK16102375.3A HK16102375A HK1214172A1 HK 1214172 A1 HK1214172 A1 HK 1214172A1 HK 16102375 A HK16102375 A HK 16102375A HK 1214172 A1 HK1214172 A1 HK 1214172A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- methods
- nervous system
- pharmacological agents
- agents targeting
- compositions related
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/57545—Neuropeptide Y
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/655—Somatostatins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/655—Somatostatins
- C07K14/6555—Somatostatins at least 1 amino acid in D-form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1019—Tetrapeptides with the first amino acid being basic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US75704706P | 2006-01-05 | 2006-01-05 | |
US84402406P | 2006-09-11 | 2006-09-11 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1214172A1 true HK1214172A1 (zh) | 2016-07-22 |
Family
ID=38256917
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK16102375.3A HK1214172A1 (zh) | 2006-01-05 | 2016-03-01 | 與改善靶向神經系統的藥理學試劑的性質有關的方法和組合物 |
Country Status (9)
Country | Link |
---|---|
US (4) | US8435940B2 (zh) |
EP (3) | EP2545933A3 (zh) |
JP (5) | JP2009523129A (zh) |
KR (1) | KR20090009189A (zh) |
CA (1) | CA2636469A1 (zh) |
HK (1) | HK1214172A1 (zh) |
RU (1) | RU2008132149A (zh) |
TW (2) | TWI406671B (zh) |
WO (1) | WO2007081792A2 (zh) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7485706B2 (en) * | 2003-07-30 | 2009-02-03 | The Board Of Trustees Of The Leland Stanford Junior University | Neurodegenerative protein aggregation inhibition methods and compounds |
RU2008132149A (ru) | 2006-01-05 | 2010-02-10 | Юниверсити Оф Юта Рисерч Фаундейшн (Us) | Способы и композиции, имеющие отношение к улучшенным свойствам фармакологических средств, целенаправленно действующих на нервную систему |
US20110064671A1 (en) * | 2008-03-10 | 2011-03-17 | Cornell University | Modulation of blood brain barrier permeability |
WO2010043566A2 (de) | 2008-10-17 | 2010-04-22 | Sanofi-Aventis Deutschland Gmbh | Kombination von einem insulin und einem glp-1-agonisten |
US9707176B2 (en) | 2009-11-13 | 2017-07-18 | Sanofi-Aventis Deutschland Gmbh | Pharmaceutical composition comprising a GLP-1 agonist and methionine |
ES2855146T3 (es) | 2009-11-13 | 2021-09-23 | Sanofi Aventis Deutschland | Composición farmacéutica que comprende un agonista de GLP-1, una insulina y metionina |
PT2611458T (pt) | 2010-08-30 | 2016-12-16 | Sanofi Aventis Deutschland | Utilização de ave0010 para o fabrico de um medicamento para o tratamento da diabetes mellitus tipo 2 |
WO2012082942A2 (en) | 2010-12-15 | 2012-06-21 | Neuroadjuvants, Inc. | Neuropeptide analogs, compositions, and methods for treating pain |
US9821032B2 (en) | 2011-05-13 | 2017-11-21 | Sanofi-Aventis Deutschland Gmbh | Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin |
TWI559929B (en) | 2011-09-01 | 2016-12-01 | Sanofi Aventis Deutschland | Pharmaceutical composition for use in the treatment of a neurodegenerative disease |
US20140056870A1 (en) * | 2012-08-27 | 2014-02-27 | Allergan, Inc. | Fusion proteins |
CN103175973B (zh) * | 2013-02-26 | 2015-05-13 | 首都医科大学 | 甘丙肽在制备女性抑郁症检测工具中的应用 |
ES2728319T3 (es) | 2013-09-18 | 2019-10-23 | Bcn Peptides Sa | Análogos de cortistatina para el tratamiento de enfermedades inflamatorias y/o inmunes |
CN107206058A (zh) | 2014-12-12 | 2017-09-26 | 赛诺菲-安万特德国有限公司 | 甘精胰岛素/利西拉来固定比率配制剂 |
TWI748945B (zh) | 2015-03-13 | 2021-12-11 | 德商賽諾菲阿凡提斯德意志有限公司 | 第2型糖尿病病患治療 |
TW201705975A (zh) | 2015-03-18 | 2017-02-16 | 賽諾菲阿凡提斯德意志有限公司 | 第2型糖尿病病患之治療 |
KR101885238B1 (ko) * | 2015-11-30 | 2018-08-06 | 주식회사 뉴라클사이언스 | 스펙신 기반 갈라닌 2형 수용체의 효현제 및 이의 용도 |
CA3027784A1 (en) * | 2016-06-16 | 2017-12-21 | Charite - Universitatsmedizin Berlin | Neuropeptide-expressing vectors and methods for the treatment of epilepsy |
GB201620611D0 (en) | 2016-12-05 | 2017-01-18 | Univ Of Lancaster | Treatment of neurological diseases |
US10376555B2 (en) * | 2017-04-07 | 2019-08-13 | Hong Kong Baptist University | Identification of cyclic peptide agonists of galanin receptor 2 and 3 guided by spexin solution structure |
ES2780274A1 (es) | 2019-02-15 | 2020-08-24 | Consejo Superior De Investig Científicas (Csic) | Cortistatina o un análogo de la misma como agente farmacéuticamente activo en forma latente |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1601438A (zh) | 1968-10-17 | 1970-08-24 | ||
US4897355A (en) | 1985-01-07 | 1990-01-30 | Syntex (U.S.A.) Inc. | N[ω,(ω-1)-dialkyloxy]- and N-[ω,(ω-1)-dialkenyloxy]-alk-1-yl-N,N,N-tetrasubstituted ammonium lipids and uses therefor |
IL79289A (en) | 1985-07-05 | 1992-01-15 | Whitehead Biomedical Inst | Introduction and expression of foreign genetic material into keratinocytes using a recombinant retrovirus |
US4980286A (en) | 1985-07-05 | 1990-12-25 | Whitehead Institute For Biomedical Research | In vivo introduction and expression of foreign genetic material in epithelial cells |
US4704692A (en) | 1986-09-02 | 1987-11-03 | Ladner Robert C | Computer based system and method for determining and displaying possible chemical structures for converting double- or multiple-chain polypeptides to single-chain polypeptides |
JP2917998B2 (ja) | 1988-02-05 | 1999-07-12 | ホワイトヘッド・インスティチュート・フォー・バイオメディカル・リサーチ | 修飾された肝細胞およびその用途 |
CA1339354C (en) | 1988-09-01 | 1997-08-26 | The Whitehead Institute For Biomedical Research | Recombinant retroviruses with amphotropic and ecotropic host ranges |
JPH02159990A (ja) | 1988-12-10 | 1990-06-20 | Fanuc Ltd | サーボモータの速度制御方式 |
SE9101472D0 (sv) | 1991-05-15 | 1991-05-15 | Trion Forskning & Utveckling | Galanin antagonist |
FR2677652B1 (fr) | 1991-06-12 | 2005-05-27 | Agronomique Inst Nat Rech | Procede de preparation d'une proteine d'interet dans le lait d'un animal transgenique, produit obtenu et cellule eucaryote utilisee. |
US5965788A (en) | 1992-06-12 | 1999-10-12 | Institut National De La Recherche Agronomique | Transgenic non-human mammal comprising a rabbit WAP promoter |
US6261834B1 (en) | 1991-11-08 | 2001-07-17 | Research Corporation Technologies, Inc. | Vector for gene therapy |
US5670477A (en) * | 1995-04-20 | 1997-09-23 | Joseph F. Poduslo | Method to enhance permeability of the blood/brain blood/nerve bariers to therapeutic agents |
GB9917724D0 (en) * | 1999-07-28 | 1999-09-29 | Medical Res Council | Peptides |
DE60032255T2 (de) | 1999-10-04 | 2007-06-28 | Nektar Therapeutics Al, Corp., Huntsville | Polymer-stabilisierte neuropeptide |
EP2138583A1 (en) | 2000-12-22 | 2009-12-30 | Institut National De La Recherche Agronomique | Position-independent and tissue specific expression of a transgene in milk of transgenic animals |
US6858580B2 (en) | 2001-06-04 | 2005-02-22 | Nobex Corporation | Mixtures of drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same |
ES2815927T3 (es) | 2003-12-10 | 2021-03-31 | Nektar Therapeutics | Composiciones que comprenden dos poblaciones diferentes de conjugados de polímero-agente activo |
CN102895666B (zh) | 2003-12-16 | 2015-08-19 | 尼克塔治疗公司 | 化学改性的小分子 |
JP5058991B2 (ja) | 2005-06-29 | 2012-10-24 | コンプメディクス リミテッド | 導電ブリッジを備えるセンサ・アセンブリ |
RU2008132149A (ru) | 2006-01-05 | 2010-02-10 | Юниверсити Оф Юта Рисерч Фаундейшн (Us) | Способы и композиции, имеющие отношение к улучшенным свойствам фармакологических средств, целенаправленно действующих на нервную систему |
WO2012000020A1 (en) | 2010-06-28 | 2012-01-05 | Wood, Stephen Raymond | Temporary fence base |
WO2012082942A2 (en) | 2010-12-15 | 2012-06-21 | Neuroadjuvants, Inc. | Neuropeptide analogs, compositions, and methods for treating pain |
-
2007
- 2007-01-05 RU RU2008132149/15A patent/RU2008132149A/ru not_active Application Discontinuation
- 2007-01-05 EP EP12153130.5A patent/EP2545933A3/en not_active Withdrawn
- 2007-01-05 WO PCT/US2007/000261 patent/WO2007081792A2/en active Application Filing
- 2007-01-05 US US12/160,035 patent/US8435940B2/en not_active Expired - Fee Related
- 2007-01-05 EP EP07717960.4A patent/EP1978987B1/en not_active Not-in-force
- 2007-01-05 CA CA002636469A patent/CA2636469A1/en not_active Abandoned
- 2007-01-05 TW TW096100621A patent/TWI406671B/zh active
- 2007-01-05 EP EP14200660.0A patent/EP2913056A1/en not_active Withdrawn
- 2007-01-05 JP JP2008549570A patent/JP2009523129A/ja active Pending
- 2007-01-05 TW TW102120233A patent/TWI515007B/zh not_active IP Right Cessation
- 2007-01-05 KR KR1020087019134A patent/KR20090009189A/ko not_active Application Discontinuation
-
2012
- 2012-07-06 JP JP2012152861A patent/JP2012229241A/ja active Pending
-
2013
- 2013-03-29 US US13/853,945 patent/US8933020B2/en not_active Expired - Fee Related
-
2014
- 2014-04-17 JP JP2014085431A patent/JP6251115B2/ja not_active Expired - Fee Related
- 2014-12-02 US US14/558,570 patent/US9586999B2/en active Active
-
2015
- 2015-12-01 JP JP2015234676A patent/JP2016074713A/ja active Pending
-
2016
- 2016-03-01 HK HK16102375.3A patent/HK1214172A1/zh unknown
-
2017
- 2017-09-22 JP JP2017182515A patent/JP2018027092A/ja active Pending
-
2018
- 2018-04-18 US US15/956,625 patent/US20180340012A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP2545933A2 (en) | 2013-01-16 |
JP2014147394A (ja) | 2014-08-21 |
TW200806312A (en) | 2008-02-01 |
US8933020B2 (en) | 2015-01-13 |
US20180340012A1 (en) | 2018-11-29 |
EP2913056A1 (en) | 2015-09-02 |
TWI406671B (zh) | 2013-09-01 |
US20150203554A1 (en) | 2015-07-23 |
US9586999B2 (en) | 2017-03-07 |
WO2007081792A2 (en) | 2007-07-19 |
JP2018027092A (ja) | 2018-02-22 |
JP6251115B2 (ja) | 2017-12-20 |
EP1978987A2 (en) | 2008-10-15 |
TWI515007B (zh) | 2016-01-01 |
US20090281031A1 (en) | 2009-11-12 |
RU2008132149A (ru) | 2010-02-10 |
TW201340978A (zh) | 2013-10-16 |
EP2545933A3 (en) | 2013-04-24 |
JP2016074713A (ja) | 2016-05-12 |
US8435940B2 (en) | 2013-05-07 |
JP2009523129A (ja) | 2009-06-18 |
EP1978987A4 (en) | 2009-09-30 |
JP2012229241A (ja) | 2012-11-22 |
CA2636469A1 (en) | 2007-07-19 |
WO2007081792A3 (en) | 2007-12-06 |
EP1978987B1 (en) | 2014-12-31 |
US20130244947A1 (en) | 2013-09-19 |
KR20090009189A (ko) | 2009-01-22 |
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