HK1211495A1 - Methods for treating conditions associated with masp-2 dependent complement activation masp-2 - Google Patents

Methods for treating conditions associated with masp-2 dependent complement activation masp-2

Info

Publication number
HK1211495A1
HK1211495A1 HK15112489.6A HK15112489A HK1211495A1 HK 1211495 A1 HK1211495 A1 HK 1211495A1 HK 15112489 A HK15112489 A HK 15112489A HK 1211495 A1 HK1211495 A1 HK 1211495A1
Authority
HK
Hong Kong
Prior art keywords
masp
methods
conditions associated
complement activation
treating conditions
Prior art date
Application number
HK15112489.6A
Other languages
English (en)
Chinese (zh)
Inventor
Hans-Wilhelm Schwaeble
Cordula M Stover
Clark E Tedford
James B Parent
Teizo Fujita
Original Assignee
Omeros Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Omeros Corp filed Critical Omeros Corp
Publication of HK1211495A1 publication Critical patent/HK1211495A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • A01K67/0276—Knock-out vertebrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/07—Animals genetically altered by homologous recombination
    • A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/105—Murine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Environmental Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Microbiology (AREA)
  • Cardiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Engineering & Computer Science (AREA)
  • Animal Husbandry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Biophysics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
HK15112489.6A 2004-06-10 2015-12-18 Methods for treating conditions associated with masp-2 dependent complement activation masp-2 HK1211495A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US57884704P 2004-06-10 2004-06-10

Publications (1)

Publication Number Publication Date
HK1211495A1 true HK1211495A1 (en) 2016-05-27

Family

ID=35355643

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15112489.6A HK1211495A1 (en) 2004-06-10 2015-12-18 Methods for treating conditions associated with masp-2 dependent complement activation masp-2

Country Status (16)

Country Link
US (1) US20060002937A1 (pt)
EP (15) EP3047858A1 (pt)
CN (2) CN101018565A (pt)
AU (1) AU2005254044B2 (pt)
CA (4) CA2573144C (pt)
CY (3) CY1125022T1 (pt)
DK (3) DK2446900T3 (pt)
ES (4) ES2628867T3 (pt)
HK (1) HK1211495A1 (pt)
HU (3) HUE032349T2 (pt)
LT (3) LT2465534T (pt)
PL (3) PL1753456T3 (pt)
PT (3) PT2446900T (pt)
SI (2) SI2465534T1 (pt)
TR (1) TR201708554T4 (pt)
WO (1) WO2005123128A2 (pt)

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US7919094B2 (en) * 2004-06-10 2011-04-05 Omeros Corporation Methods for treating conditions associated with MASP-2 dependent complement activation
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US8840893B2 (en) 2004-06-10 2014-09-23 Omeros Corporation Methods for treating conditions associated with MASP-2 dependent complement activation
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AU2013201443B2 (en) * 2009-10-16 2015-02-05 Omeros Corporation Methods for treating disseminated intravascular coagulation by inhibiting MASP-2 dependent complement activation
MX344322B (es) * 2009-10-16 2016-12-13 Omeros Corp Uso de una composición que comprende un agente inhibidor de masp-2 efectivo para inhibir o prevenir la aparición de agregados en la vaculatura de un sujeto que sufre de un desorden de coagulación mediado por complemento.
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US9644035B2 (en) 2011-04-08 2017-05-09 Omeros Corporation Methods for treating conditions associated with MASP-2 dependent complement activation
AU2013201627B2 (en) * 2011-04-08 2016-02-11 Omeros Corporation Methods for treating conditions associated with MASP-2 dependent complement activation
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CN112638417A (zh) * 2018-06-22 2021-04-09 奥默罗斯公司 用于治疗各种血栓性疾病和病症的抑制masp-2的组合物和方法
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TWI834025B (zh) * 2020-03-06 2024-03-01 美商奥默羅斯公司 用於治療和/或預防冠狀病毒誘導的急性呼吸窘迫症候群的抑制masp-2的方法
CN111830254B (zh) * 2020-07-29 2022-07-26 武汉生之源生物科技股份有限公司 一种基质金属蛋白酶-3测定试剂盒及其制备方法
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EP2465534A1 (en) 2012-06-20
HUE032349T2 (en) 2017-09-28
CA2573144A1 (en) 2005-12-29
EP1753456A2 (en) 2007-02-21
CA3102252A1 (en) 2005-12-29
HUE033239T2 (hu) 2017-11-28
EP2460537A1 (en) 2012-06-06
HUE029437T2 (en) 2017-02-28
PT2465534T (pt) 2017-06-27
CN101018565A (zh) 2007-08-15
EP2446900B1 (en) 2017-03-29
EP3530288A2 (en) 2019-08-28
TR201708554T4 (tr) 2019-02-21
CY1119343T1 (el) 2018-02-14
WO2005123128A3 (en) 2007-01-25
WO2005123128A2 (en) 2005-12-29
US20060002937A1 (en) 2006-01-05
LT1753456T (lt) 2016-11-10
AU2005254044A1 (en) 2005-12-29
ES2628867T3 (es) 2017-08-04
PT2446900T (pt) 2017-06-28
CY1119339T1 (el) 2018-02-14
CA2573144C (en) 2014-07-22
LT2465534T (lt) 2017-07-25
EP2446900A1 (en) 2012-05-02
PL1753456T3 (pl) 2017-01-31
ES2671052T3 (es) 2018-06-04
EP2386316B1 (en) 2018-02-28
ES2601497T3 (es) 2017-02-15
SI2465534T1 (sl) 2017-08-31
PL2465534T3 (pl) 2017-08-31
EP2382991A1 (en) 2011-11-02
EP2457585A1 (en) 2012-05-30
DK2465534T3 (en) 2017-07-03
CY1125022T1 (el) 2022-07-22
SI2446900T1 (sl) 2017-08-31
EP2386317A1 (en) 2011-11-16
EP3530288A3 (en) 2019-12-18
CA2998633A1 (en) 2005-12-29
EP2392350A1 (en) 2011-12-07
EP2386315A1 (en) 2011-11-16
ES2631127T3 (es) 2017-08-28
CN104721824A (zh) 2015-06-24
LT2446900T (lt) 2017-07-25
EP2465534B1 (en) 2017-03-29
PT1753456T (pt) 2016-11-04
CA2998633C (en) 2021-01-26
CA2847677C (en) 2018-05-01
EP2446901A1 (en) 2012-05-02
DK2446900T3 (en) 2017-07-10
EP2386316A1 (en) 2011-11-16
EP2465535A1 (en) 2012-06-20
CA2847677A1 (en) 2005-12-29
EP1753456B1 (en) 2016-08-10
DK1753456T3 (en) 2016-11-28
EP2446902A1 (en) 2012-05-02
AU2005254044B2 (en) 2011-09-29
PL2446900T3 (pl) 2017-09-29
EP3047858A1 (en) 2016-07-27

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