HK1210168A1 - Amine salt and crystals thereof - Google Patents

Amine salt and crystals thereof

Info

Publication number
HK1210168A1
HK1210168A1 HK15111010.6A HK15111010A HK1210168A1 HK 1210168 A1 HK1210168 A1 HK 1210168A1 HK 15111010 A HK15111010 A HK 15111010A HK 1210168 A1 HK1210168 A1 HK 1210168A1
Authority
HK
Hong Kong
Prior art keywords
crystals
amine salt
amine
salt
Prior art date
Application number
HK15111010.6A
Other languages
English (en)
Chinese (zh)
Inventor
Kousuke Tani
Akihiro Kinoshita
Keisuke Hanada
Yoshiyuki Aratani
Takahiro Nekado
Atsushi Shimabukuro
Original Assignee
Ono Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ono Pharmaceutical Co filed Critical Ono Pharmaceutical Co
Publication of HK1210168A1 publication Critical patent/HK1210168A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/56Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/4261,3-Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40Cyclodextrins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/10Drugs for disorders of the urinary system of the bladder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0012Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
    • C08B37/0015Inclusion compounds, i.e. host-guest compounds, e.g. polyrotaxanes
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/16Cyclodextrin; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Biochemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Materials Engineering (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Hydrogenated Pyridines (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
HK15111010.6A 2012-08-31 2015-11-09 Amine salt and crystals thereof HK1210168A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2012191080 2012-08-31
PCT/JP2013/073442 WO2014034902A1 (ja) 2012-08-31 2013-08-30 アミン塩とその結晶

Publications (1)

Publication Number Publication Date
HK1210168A1 true HK1210168A1 (en) 2016-04-15

Family

ID=50183705

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15111010.6A HK1210168A1 (en) 2012-08-31 2015-11-09 Amine salt and crystals thereof

Country Status (24)

Country Link
US (1) US9643940B2 (xx)
EP (1) EP2891651B1 (xx)
JP (1) JP6131956B2 (xx)
KR (1) KR102119619B1 (xx)
CN (1) CN104603117B (xx)
AU (1) AU2013309872B2 (xx)
BR (1) BR112015004459B1 (xx)
CA (1) CA2882732C (xx)
DK (1) DK2891651T3 (xx)
ES (1) ES2623788T3 (xx)
HK (1) HK1210168A1 (xx)
HU (1) HUE032816T2 (xx)
IL (1) IL237432B (xx)
MX (1) MX344385B (xx)
MY (1) MY177737A (xx)
NZ (1) NZ705340A (xx)
PH (1) PH12015500389A1 (xx)
PL (1) PL2891651T3 (xx)
PT (1) PT2891651T (xx)
RU (1) RU2658823C2 (xx)
SG (1) SG11201501451SA (xx)
TW (1) TWI597274B (xx)
WO (1) WO2014034902A1 (xx)
ZA (1) ZA201501374B (xx)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022543401A (ja) * 2019-08-04 2022-10-12 イエダ リサーチ アンド デベロップメント カンパニー リミテッド フルエンスルホンの製造方法

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS503362B1 (xx) 1970-06-10 1975-02-04
JPS5231404B1 (xx) 1971-04-28 1977-08-15
FR2204408A1 (en) * 1972-10-27 1974-05-24 Wirth Pierre Phenylbutazone salts - sol in water and well tolerated
JPS57156460A (en) 1981-03-20 1982-09-27 Ono Pharmaceut Co Ltd Stabilized composition of prostaglandin and prostaglandin mimic compound, and its preparation
JPS60197667A (ja) 1984-03-19 1985-10-07 Ono Pharmaceut Co Ltd 6―ケト―プロスタグランジン類似化合物及びその製造方法
DK1008588T3 (da) 1997-02-10 2003-07-28 Ono Pharmaceutical Co 11,15-O-dialkylprostaglandin E derivater, fremgangsmåder til fremstilling deraf og farmaceutiske sammensætninger, der omfatter dem som virksom bestanddel
JPH11130678A (ja) 1997-08-27 1999-05-18 Kaken Pharmaceut Co Ltd 神経圧迫による神経障害改善剤
IL159996A0 (en) 2001-07-23 2004-06-20 Ono Pharmaceutical Co Remedies for diseases with bone mass loss having ep4 agonist as the active ingredient
WO2003074483A1 (fr) 2002-03-05 2003-09-12 Ono Pharmaceutical Co., Ltd. Composes derives de 8 azaprostaglandine et medicaments contenant ceux-ci comme principe actif
WO2004008411A1 (en) 2002-07-11 2004-01-22 Nokia Corporation Method and device for automatically changing a digital content on a mobile device according to sensor data
WO2004065365A1 (ja) 2003-01-21 2004-08-05 Ono Pharmaceutical Co., Ltd. 8−アザプロスタグランジン誘導体およびその医薬用途
US20070167403A1 (en) 2003-04-03 2007-07-19 Yoshifumi Takenobu Remedy for spinal canal stenosis
EP1707208A4 (en) 2003-12-05 2010-03-17 Ono Pharmaceutical Co PROMOTER OF BLOOD FLOW IN THE TISSUES OF THE HORSE TAIL
WO2005061492A1 (ja) 2003-12-22 2005-07-07 Ono Pharmaceutical Co., Ltd. 含窒素複素環化合物およびそれらを有効成分とする薬剤
JP4888775B2 (ja) 2004-08-10 2012-02-29 小野薬品工業株式会社 Ep4アゴニストを含有してなる下部尿路系疾患の予防および/または治療剤
JP4893999B2 (ja) 2004-10-22 2012-03-07 小野薬品工業株式会社 吸入用医薬組成物
TWI404529B (zh) * 2005-06-03 2013-08-11 Ono Pharmaceutical Co 神經再生及/或保護劑
JP5630264B2 (ja) 2008-06-06 2014-11-26 小野薬品工業株式会社 膀胱排尿筋収縮および尿道括約筋弛緩剤
CN102803239B (zh) * 2009-06-10 2015-04-15 小野药品工业株式会社 具有膀胱排尿肌收缩活性和尿道括约肌舒张活性的化合物

Also Published As

Publication number Publication date
KR102119619B1 (ko) 2020-06-05
ES2623788T3 (es) 2017-07-12
EP2891651A4 (en) 2016-01-27
NZ705340A (en) 2018-06-29
IL237432B (en) 2019-05-30
US20150218114A1 (en) 2015-08-06
EP2891651B1 (en) 2017-03-08
DK2891651T3 (en) 2017-06-06
HUE032816T2 (en) 2017-11-28
MX2015002209A (es) 2015-05-08
PH12015500389B1 (en) 2015-04-27
SG11201501451SA (en) 2015-04-29
US9643940B2 (en) 2017-05-09
CA2882732C (en) 2021-03-30
TWI597274B (zh) 2017-09-01
BR112015004459A2 (pt) 2017-07-04
AU2013309872A1 (en) 2015-03-19
PL2891651T3 (pl) 2017-08-31
ZA201501374B (en) 2016-03-30
CA2882732A1 (en) 2014-03-06
IL237432A0 (en) 2015-04-30
CN104603117A (zh) 2015-05-06
TW201414722A (zh) 2014-04-16
WO2014034902A1 (ja) 2014-03-06
KR20150047500A (ko) 2015-05-04
CN104603117B (zh) 2018-03-23
EP2891651A1 (en) 2015-07-08
PT2891651T (pt) 2017-05-08
PH12015500389A1 (en) 2015-04-27
JPWO2014034902A1 (ja) 2016-08-08
AU2013309872B2 (en) 2017-09-14
MY177737A (en) 2020-09-23
BR112015004459B1 (pt) 2020-06-30
JP6131956B2 (ja) 2017-05-24
RU2015111568A (ru) 2016-10-20
RU2658823C2 (ru) 2018-06-25
MX344385B (es) 2016-12-14

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20220826