HK1208826A1 - 新穎的化合物 - Google Patents

新穎的化合物

Info

Publication number
HK1208826A1
HK1208826A1 HK15109639.1A HK15109639A HK1208826A1 HK 1208826 A1 HK1208826 A1 HK 1208826A1 HK 15109639 A HK15109639 A HK 15109639A HK 1208826 A1 HK1208826 A1 HK 1208826A1
Authority
HK
Hong Kong
Prior art keywords
novel compounds
novel
compounds
Prior art date
Application number
HK15109639.1A
Other languages
English (en)
Inventor
Diane Mary Coe
Stephen Allan Smith
Original Assignee
Glaxosmithkline Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Llc filed Critical Glaxosmithkline Llc
Publication of HK1208826A1 publication Critical patent/HK1208826A1/zh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Otolaryngology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HK15109639.1A 2012-11-20 2015-09-30 新穎的化合物 HK1208826A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261728390P 2012-11-20 2012-11-20
US201361774087P 2013-03-07 2013-03-07
PCT/US2013/070472 WO2014081645A1 (en) 2012-11-20 2013-11-18 Novel compounds

Publications (1)

Publication Number Publication Date
HK1208826A1 true HK1208826A1 (zh) 2016-03-18

Family

ID=50776485

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15109639.1A HK1208826A1 (zh) 2012-11-20 2015-09-30 新穎的化合物

Country Status (32)

Country Link
US (3) US9540383B2 (zh)
EP (1) EP2922549B1 (zh)
JP (1) JP6228223B2 (zh)
KR (1) KR20150085055A (zh)
CN (1) CN104780922B (zh)
AU (1) AU2013348218B2 (zh)
BR (1) BR112015011400A8 (zh)
CA (1) CA2892218A1 (zh)
CL (1) CL2015001342A1 (zh)
CR (1) CR20150268A (zh)
CY (1) CY1119557T1 (zh)
DK (1) DK2922549T3 (zh)
DO (1) DOP2015000121A (zh)
EA (1) EA028480B1 (zh)
ES (1) ES2639789T3 (zh)
HK (1) HK1208826A1 (zh)
HR (1) HRP20171150T1 (zh)
HU (1) HUE13857477T2 (zh)
IL (1) IL238800B (zh)
LT (1) LT2922549T (zh)
ME (1) ME02867B (zh)
MX (1) MX358025B (zh)
NZ (1) NZ707319A (zh)
PE (1) PE20151086A1 (zh)
PH (1) PH12015501100B1 (zh)
PL (1) PL2922549T3 (zh)
PT (1) PT2922549T (zh)
RS (1) RS56233B1 (zh)
SG (1) SG11201503282RA (zh)
SI (1) SI2922549T1 (zh)
UA (1) UA114645C2 (zh)
WO (1) WO2014081645A1 (zh)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA103195C2 (uk) 2008-08-11 2013-09-25 Глаксосмитклайн Ллк Похідні пурину для застосування у лікуванні алергій, запальних та інфекційних захворювань
LT2734186T (lt) 2011-07-22 2018-12-10 Glaxosmithkline Llc Kompozicija
ES2653254T3 (es) 2012-08-24 2018-02-06 Glaxosmithkline Llc Compuestos de pirazolopirimidina
WO2014081644A1 (en) 2012-11-20 2014-05-30 Glaxosmithkline Llc Novel compounds
CN104780922B (zh) 2012-11-20 2016-09-07 葛兰素史克有限责任公司 干扰素诱导剂化合物
AU2013348216B2 (en) 2012-11-20 2016-10-13 Glaxosmithkline Llc Novel compounds
ES2655940T3 (es) * 2014-02-20 2018-02-22 Glaxosmithkline Intellectual Property (No. 2) Limited Derivados de pirrolo[3,2-d]pirimidina como inductores de interferón humano
EP3190113B1 (en) * 2014-08-15 2021-05-19 Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Pyrrolopyrimidine compounds used as tlr7 agonist
CN105732635A (zh) * 2014-12-29 2016-07-06 南京明德新药研发股份有限公司 一类Toll样受体7激动剂
TWI558709B (zh) * 2015-10-07 2016-11-21 Chia Tai Tianqing Pharmaceutical Group Co Ltd Pyrrolopyrimidine ring compounds, their use and pharmaceutical compositions
EP3381918B1 (en) 2015-11-05 2020-09-16 Chia Tai Tianqing Pharmaceutical Group Co., Ltd. 7-(thiazol-5-yl) pyrrolopyrimidine compound as tlr7 agonist
CN107043378A (zh) * 2016-02-05 2017-08-15 正大天晴药业集团股份有限公司 一种吡咯并[3,2-d]嘧啶类化合物的制备方法及其中间体
CN107043379A (zh) 2016-02-05 2017-08-15 正大天晴药业集团股份有限公司 一种tlr7激动剂的晶型a、其制备方法和医药用途
CN107043380A (zh) * 2016-02-05 2017-08-15 正大天晴药业集团股份有限公司 一种tlr7激动剂的马来酸盐、其晶型c、晶型d、晶型e、制备方法和用途

Family Cites Families (88)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW574214B (en) 1994-06-08 2004-02-01 Pfizer Corticotropin releasing factor antagonists
US7125880B1 (en) 1995-06-06 2006-10-24 Pfizer Inc. Corticotropin releasing factor antagonists
US6403599B1 (en) 1995-11-08 2002-06-11 Pfizer Inc Corticotropin releasing factor antagonists
WO1997049706A1 (en) * 1996-06-25 1997-12-31 Novartis Ag SUBSTITUTED 7-AMINO-PYRROLO[3,2-d]PYRIMIDINES AND THE USE THEREOF
US5985848A (en) * 1997-10-14 1999-11-16 Albert Einstein College Of Medicine Of Yeshiva University Inhibitors of nucleoside metabolism
TW572758B (en) 1997-12-22 2004-01-21 Sumitomo Pharma Type 2 helper T cell-selective immune response inhibitors comprising purine derivatives
US6187777B1 (en) 1998-02-06 2001-02-13 Amgen Inc. Compounds and methods which modulate feeding behavior and related diseases
US6232320B1 (en) 1998-06-04 2001-05-15 Abbott Laboratories Cell adhesion-inhibiting antiinflammatory compounds
CZ27399A3 (cs) 1999-01-26 2000-08-16 Ústav Experimentální Botaniky Av Čr Substituované dusíkaté heterocyklické deriváty, způsob jejich přípravy, tyto deriváty pro použití jako léčiva, farmaceutická kompozice a kombinovaný farmaceutický přípravek tyto deriváty obsahující a použití těchto derivátů pro výrobu léčiv
AU3540101A (en) 2000-01-07 2001-07-16 Universitaire Instelling Antwerpen Purine derivatives, process for their preparation and use thereof
TW200505900A (en) 2000-04-28 2005-02-16 Acadia Pharm Inc Muscarinic agonists
GB0114286D0 (en) 2001-06-12 2001-08-01 Hoffmann La Roche Nucleoside Derivatives
TW200301251A (en) 2001-12-20 2003-07-01 Wyeth Corp Azaindolylalkylamine derivatives as 5-hydroxytryptamine-6 ligands
DE60237425D1 (de) 2002-03-28 2010-10-07 Univerzita Palackeho V Olomouc PyrazoloÄ4,3-dÜpyrimidine, Verfahren zu ihrer Herstellung und therapeutische Anwendung
AU2003232071A1 (en) * 2002-05-06 2003-11-17 Genelabs Technologies, Inc. Nucleoside derivatives for treating hepatitis c virus infection
US6713241B2 (en) 2002-08-09 2004-03-30 Eastman Kodak Company Thermally developable emulsions and imaging materials containing binder mixture
EP1539783B1 (en) 2002-08-21 2011-04-13 Albert Einstein College Of Medicine Of Yeshiva University Inhibitors of nucleoside phosphorylases and nucleosidases
NZ539064A (en) 2002-09-27 2007-09-28 Dainippon Sumitomo Pharma Co Novel adenine compound and use thereof
CA2530081A1 (en) 2003-07-01 2005-01-13 Merck & Co., Inc. Ophthalmic compositions for treating ocular hypertension
WO2005020892A2 (en) 2003-08-08 2005-03-10 Mitochroma Research, Inc. Pharmaceutical compositions and methods for metabolic modulation
OA13310A (en) 2003-09-05 2007-04-13 Anadys Pharmaceuticals Inc TLR7 ligands for the treatment of hepatitis C.
UY28506A1 (es) 2003-09-12 2005-04-29 Basf Ag 6-halógeno-(1,2,4)triazolo(1,5-a)pirimidinas para combatir plagas animales.
BRPI0414867A (pt) 2003-10-03 2006-11-21 3M Innovative Properties Co pirazolopiridinas e seus análogos
WO2005092892A1 (ja) 2004-03-26 2005-10-06 Dainippon Sumitomo Pharma Co., Ltd. 8−オキソアデニン化合物
TWI414525B (zh) 2004-03-26 2013-11-11 Dainippon Sumitomo Pharma Co 9-取代-8-氧基腺嘌呤化合物
AP2139A (en) 2004-04-02 2010-08-21 Osi Pharm Inc 6,6-bicyclic ring substituted heterobicyclic protein kinase inhibitors.
US20060074102A1 (en) 2004-05-14 2006-04-06 Kevin Cusack Kinase inhibitors as therapeutic agents
US20060029642A1 (en) 2004-08-03 2006-02-09 Dusan Miljkovic Methods and compositions for improved chromium complexes
GB0420719D0 (en) 2004-09-17 2004-10-20 Addex Pharmaceuticals Sa Novel allosteric modulators
EA200702235A1 (ru) 2005-05-04 2008-04-28 Пфайзер Лимитед Производные 2-амидо-6-амино-8-оксопурина в качестве модуляторов toll-подобных рецепторов для лечения рака и вирусных инфекций, таких как гепатит с
NZ540160A (en) 2005-05-20 2008-03-28 Einstein Coll Med Inhibitors of nucleoside phosphorylases
AU2006272876A1 (en) 2005-07-22 2007-02-01 Sunesis Pharmaceuticals, Inc. Pyrazolo pyrimidines useful as aurora kinase inhibitors
US20090324551A1 (en) 2005-08-22 2009-12-31 The Regents Of The University Of California Office Of Technology Transfer Tlr agonists
ATE517883T1 (de) 2005-08-25 2011-08-15 Schering Corp Imidazolderivate als funktionelle selektive agonisten des alpha2c-adrenorezeptors
US8003624B2 (en) 2005-08-25 2011-08-23 Schering Corporation Functionally selective ALPHA2C adrenoreceptor agonists
KR20080031496A (ko) 2005-09-02 2008-04-08 화이자 인코포레이티드 히드록시 치환된 1h-이미다조피리딘 및 방법
TW200801003A (en) 2005-09-16 2008-01-01 Astrazeneca Ab Novel compounds
TW200745114A (en) 2005-09-22 2007-12-16 Astrazeneca Ab Novel compounds
EP1939198A4 (en) 2005-09-22 2012-02-15 Dainippon Sumitomo Pharma Co NEW ADENINE CONNECTION
JPWO2007034817A1 (ja) 2005-09-22 2009-03-26 大日本住友製薬株式会社 新規アデニン化合物
WO2007034917A1 (ja) 2005-09-22 2007-03-29 Dainippon Sumitomo Pharma Co., Ltd. 新規なアデニン化合物
JPWO2007034882A1 (ja) * 2005-09-22 2009-03-26 大日本住友製薬株式会社 新規アデニン化合物
EP1939200A4 (en) 2005-09-22 2010-06-16 Dainippon Sumitomo Pharma Co NEW ADENINE CONNECTION
CN1947717B (zh) 2005-10-14 2012-09-26 卓敏 选择性抑制腺苷酸环化酶1的化合物在制备用于治疗神经性疼痛和炎性疼痛的药物中的应用
EP1987030B1 (en) 2006-02-17 2011-11-09 Pfizer Limited 3 -deazapurine derivatives as tlr7 modulators
WO2007110868A2 (en) 2006-03-28 2007-10-04 Atir Holding S.A. Heterocyclic compounds and uses thereof in the treatment of sexual disorders
GB0610666D0 (en) 2006-05-30 2006-07-05 Glaxo Group Ltd Fluid dispenser
GB2438679A (en) 2006-05-31 2007-12-05 Sra Dev Ltd Ultrasonic surgical tool having two modes of vibration
US8846697B2 (en) 2006-05-31 2014-09-30 The Regents Of The University Of California Purine analogs
WO2008004948A1 (en) 2006-07-05 2008-01-10 Astrazeneca Ab 8-oxoadenine derivatives acting as modulators of tlr7
TWI399377B (zh) 2006-07-07 2013-06-21 Gilead Sciences Inc 類鐸受體7之調節劑
CL2007002994A1 (es) * 2006-10-19 2008-02-08 Wyeth Corp Compuestos derivados heterociclicos que contienen sulfamoilo, inhibidores de hsp90; composicion farmaceutica; y uso para el tratamiento del cancer, tal como cancer de mama, de colon y prostata, entre otros.
TW200831105A (en) 2006-12-14 2008-08-01 Astrazeneca Ab Novel compounds
DE602008003764D1 (de) 2007-02-19 2011-01-13 Glaxosmithkline Llc Purinderivate als immunmodulatoren
EP2139894B1 (en) 2007-03-19 2011-10-26 AstraZeneca AB 9-substituted-8-oxo-adenine compounds as toll-like receptor (tlr7) modulators
DK2132209T3 (da) 2007-03-19 2014-04-14 Astrazeneca Ab 9-substituerede 8-oxo-adeninforbindelser som modulatorer af tlr7 (toll-like receptor 7)
JPWO2008114819A1 (ja) 2007-03-20 2010-07-08 大日本住友製薬株式会社 新規アデニン化合物
PE20081887A1 (es) 2007-03-20 2009-01-16 Dainippon Sumitomo Pharma Co Nuevo compuesto de adenina
US7928111B2 (en) 2007-06-08 2011-04-19 Senomyx, Inc. Compounds including substituted thienopyrimidinone derivatives as ligands for modulating chemosensory receptors
US7968544B2 (en) 2007-06-29 2011-06-28 Gilead Sciences, Inc. Modulators of toll-like receptor 7
GB0715087D0 (en) 2007-08-03 2007-09-12 Summit Corp Plc Drug combinations for the treatment of duchenne muscular dystrophy
CN101842098A (zh) 2007-08-10 2010-09-22 基因实验室技术有限公司 用于治疗病毒感染的含氮的二环化学实体
PE20091156A1 (es) 2007-12-17 2009-09-03 Astrazeneca Ab Sales de (3-{[[3-(6-amino-2-butoxi-8-oxo-7,8-dihidro-9h-purin-9-il)propil](3-morfolin-4-ilpropil)amino]metil}fenil)acetato de metilo
WO2009151910A2 (en) 2008-05-25 2009-12-17 Wyeth Combination product of receptor tyrosine kinase inhibitor and fatty acid synthase inhibitor for treating cancer
US8946239B2 (en) 2008-07-10 2015-02-03 Duquesne University Of The Holy Spirit Substituted pyrrolo, -furano, and cyclopentylpyrimidines having antimitotic and/or antitumor activity and methods of use thereof
ITMO20080210A1 (it) 2008-08-01 2010-02-02 Marco Seghedoni Veicolo per il sollevamento e la movimentazione di manufatti
US8802684B2 (en) 2008-08-11 2014-08-12 Glaxosmithkline Llc Adenine derivatives
WO2010018132A1 (en) 2008-08-11 2010-02-18 Smithkline Beecham Corporation Compounds
EP2324025A1 (en) 2008-08-11 2011-05-25 Smithkline Beecham Corporation Purine derivatives for use in the treatment of allergic, inflammatory and infectious diseases
ES2433371T3 (es) 2008-08-11 2013-12-10 Glaxosmithkline Llc Derivados de purina para uso en el tratamiento de enfermedades alérgicas, inflamatorias e infecciosas
UA103195C2 (uk) 2008-08-11 2013-09-25 Глаксосмитклайн Ллк Похідні пурину для застосування у лікуванні алергій, запальних та інфекційних захворювань
MX2011001663A (es) 2008-08-11 2011-03-24 Glaxosmithkline Llc Derivados novedosos de adenina.
CN102548999A (zh) 2009-01-20 2012-07-04 山东轩竹医药科技有限公司 含有取代的含氮稠杂环的头孢菌素衍生物
WO2011008110A1 (en) * 2009-07-17 2011-01-20 Albert Einstein College Of Yeshiva University 3-hydroxypyrrolidine inhibitors of 5'-methylthioadenosine phosphorylase and nucleosidase
ES2732999T3 (es) 2009-08-07 2019-11-27 Glaxosmithkline Biologicals Sa Derivados de oxoadenina lipidada
BR112012018904A2 (pt) 2010-02-10 2020-09-01 Glaxosmithkline Llc composto, adjuvante de vacina, composições imunogênica, de vacina e farmacêutica, e uso de um composto"
WO2011098451A1 (en) 2010-02-10 2011-08-18 Glaxosmithkline Llc Purine derivatives and their pharmaceutical uses
WO2012009258A2 (en) 2010-07-13 2012-01-19 Edward Roberts Peptidomimetic galanin receptor modulators
WO2012092552A1 (en) 2010-12-30 2012-07-05 Selecta Biosciences, Inc. Synthetic nanocarriers with reactive groups that release biologically active agents
EP2670733B1 (en) 2011-02-01 2019-04-10 The Board of Trustees of the University of Illionis N-hydroxybenzamide derivatives as hdac inhibitors and therapeutic methods using the same
JP5813785B2 (ja) * 2011-02-04 2015-11-17 デュケイン ユニバーシティー オブ ザ ホリー スピリット 抗チューブリン活性を有する二環式および三環式のピリミジンチロシンキナーゼ阻害剤ならびに患者の処置方法
EP2713737B1 (en) * 2011-06-01 2016-04-20 Janus Biotherapeutics, Inc. Novel immune system modulators
LT2734186T (lt) 2011-07-22 2018-12-10 Glaxosmithkline Llc Kompozicija
ES2653254T3 (es) 2012-08-24 2018-02-06 Glaxosmithkline Llc Compuestos de pirazolopirimidina
WO2014081644A1 (en) 2012-11-20 2014-05-30 Glaxosmithkline Llc Novel compounds
AU2013348216B2 (en) 2012-11-20 2016-10-13 Glaxosmithkline Llc Novel compounds
CN104780922B (zh) 2012-11-20 2016-09-07 葛兰素史克有限责任公司 干扰素诱导剂化合物
ES2655940T3 (es) 2014-02-20 2018-02-22 Glaxosmithkline Intellectual Property (No. 2) Limited Derivados de pirrolo[3,2-d]pirimidina como inductores de interferón humano

Also Published As

Publication number Publication date
HRP20171150T1 (hr) 2017-10-06
BR112015011400A2 (pt) 2017-07-11
NZ707319A (en) 2019-09-27
KR20150085055A (ko) 2015-07-22
LT2922549T (lt) 2017-09-11
CY1119557T1 (el) 2018-03-07
CR20150268A (es) 2015-07-01
US9540383B2 (en) 2017-01-10
US9907847B2 (en) 2018-03-06
US20170080085A1 (en) 2017-03-23
AU2013348218B2 (en) 2016-10-13
IL238800B (en) 2018-10-31
EA201590684A1 (ru) 2016-03-31
SG11201503282RA (en) 2015-06-29
CA2892218A1 (en) 2014-05-30
ME02867B (me) 2018-04-20
BR112015011400A8 (pt) 2019-10-01
UA114645C2 (uk) 2017-07-10
AU2013348218A1 (en) 2015-06-04
EA028480B1 (ru) 2017-11-30
ES2639789T3 (es) 2017-10-30
IL238800A0 (en) 2015-06-30
CN104780922B (zh) 2016-09-07
PL2922549T3 (pl) 2017-11-30
WO2014081645A1 (en) 2014-05-30
PH12015501100A1 (en) 2015-07-27
MX2015006375A (es) 2015-10-05
EP2922549A4 (en) 2016-04-06
PH12015501100B1 (en) 2015-07-27
PT2922549T (pt) 2017-09-01
RS56233B1 (sr) 2017-11-30
HUE13857477T2 (hu) 2018-05-28
CL2015001342A1 (es) 2015-10-02
DOP2015000121A (es) 2015-11-30
JP2016500068A (ja) 2016-01-07
CN104780922A (zh) 2015-07-15
DK2922549T3 (en) 2017-09-11
SI2922549T1 (sl) 2017-10-30
MX358025B (es) 2018-08-02
EP2922549B1 (en) 2017-06-21
US20150284396A1 (en) 2015-10-08
PE20151086A1 (es) 2015-08-20
JP6228223B2 (ja) 2017-11-08
US20180140695A1 (en) 2018-05-24
EP2922549A1 (en) 2015-09-30

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