HK1208074A1 - Methods and compositions for diagnosis and prognosis of renal injury and renal failure - Google Patents

Methods and compositions for diagnosis and prognosis of renal injury and renal failure Download PDF

Info

Publication number
HK1208074A1
HK1208074A1 HK15108654.3A HK15108654A HK1208074A1 HK 1208074 A1 HK1208074 A1 HK 1208074A1 HK 15108654 A HK15108654 A HK 15108654A HK 1208074 A1 HK1208074 A1 HK 1208074A1
Authority
HK
Hong Kong
Prior art keywords
determined
urine
plasma concentration
subject
concentration
Prior art date
Application number
HK15108654.3A
Other languages
English (en)
Chinese (zh)
Inventor
.安德貝里
J.安德贝里
.格雷
J.格雷
.麥克弗森
P.麦克弗森
.中村
K.中村
坎普夫
P. 坎普夫 J.
Original Assignee
阿斯图特医药公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 阿斯图特医药公司 filed Critical 阿斯图特医药公司
Publication of HK1208074A1 publication Critical patent/HK1208074A1/xx

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701Details
    • G01N2333/4748Details p53
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/775Apolipopeptides
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/34Genitourinary disorders
    • G01N2800/347Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/50Determining the risk of developing a disease
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/60Complex ways of combining multiple protein biomarkers for diagnosis

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
HK15108654.3A 2009-08-28 2015-09-04 Methods and compositions for diagnosis and prognosis of renal injury and renal failure HK1208074A1 (en)

Applications Claiming Priority (28)

Application Number Priority Date Filing Date Title
US23812009P 2009-08-28 2009-08-28
US23813409P 2009-08-28 2009-08-28
US23812809P 2009-08-28 2009-08-28
US23812509P 2009-08-28 2009-08-28
US23811809P 2009-08-28 2009-08-28
US23812109P 2009-08-28 2009-08-28
US23812709P 2009-08-28 2009-08-28
US23812309P 2009-08-28 2009-08-28
US23812909P 2009-08-28 2009-08-28
US23811509P 2009-08-28 2009-08-28
US61/238,125 2009-08-28
US61/238,121 2009-08-28
US61/238,123 2009-08-28
US61/238,120 2009-08-28
US61/238,115 2009-08-28
US61/238,134 2009-08-28
US61/238,128 2009-08-28
US61/238,129 2009-08-28
US61/238,118 2009-08-28
US61/238,127 2009-08-28
US24399309P 2009-09-18 2009-09-18
US24400209P 2009-09-18 2009-09-18
US24399709P 2009-09-18 2009-09-18
US24399109P 2009-09-18 2009-09-18
US61/244,002 2009-09-18
US61/243,993 2009-09-18
US61/243,991 2009-09-18
US61/243,997 2009-09-18

Publications (1)

Publication Number Publication Date
HK1208074A1 true HK1208074A1 (en) 2016-02-19

Family

ID=43628398

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15108654.3A HK1208074A1 (en) 2009-08-28 2015-09-04 Methods and compositions for diagnosis and prognosis of renal injury and renal failure

Country Status (9)

Country Link
US (2) US20120315649A1 (https=)
EP (3) EP2470905B1 (https=)
JP (2) JP5775874B2 (https=)
CN (2) CN102792161B (https=)
AU (1) AU2010286559B2 (https=)
CA (1) CA2772336A1 (https=)
HK (1) HK1208074A1 (https=)
NZ (2) NZ598712A (https=)
WO (1) WO2011025917A1 (https=)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5763098B2 (ja) 2009-12-20 2015-08-12 アスチュート メディカル,インコーポレイテッド 腎損傷および腎不全の診断および予後診断のための方法ならびに組成物
PT2666872T (pt) 2010-02-05 2016-07-08 Astute Medical Inc Processos e composições para o diagnóstico e o prognóstico de lesões renais e de insuficiência renal
IN2012MN02812A (https=) 2010-06-23 2015-05-22 Astute Medical Inc
EP2899545B1 (en) * 2010-06-23 2018-08-22 Astute Medical, Inc. Methods for diagnosis and prognosis of renal injury and renal failure
US10557856B2 (en) * 2010-09-24 2020-02-11 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Biomarkers of renal injury
EP2668497B1 (en) * 2011-01-26 2020-03-25 University of Pittsburgh - Of the Commonwealth System of Higher Education Urine biomarkers for prediction of recovery after acute kidney injury : proteomics
EP2503340A1 (en) * 2011-03-22 2012-09-26 Fundació Institut de Recerca Hospital Universitari Vall d'Hebron, Fundació Privada Diagnostic marker for relapsing primary idiopathic focal segmental glomerulosclerosis
TW201250248A (en) * 2011-04-25 2012-12-16 Kyowa Medex Co Ltd Prognostication method of renal failure
WO2012155123A2 (en) * 2011-05-12 2012-11-15 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
ES2734494T3 (es) 2011-12-08 2019-12-10 Astute Medical Inc Métodos y usos para el diagnóstico de una lesión renal y de una insuficiencia renal
EP2834638B1 (en) * 2012-04-02 2020-02-12 Astute Medical, Inc. Methods for diagnosis and prognosis of sepsis
TR201807542T4 (tr) 2013-01-17 2018-06-21 Astute Medical Inc Böbrek hasarı ve böbrek yetmezliği teşhisi ve prognozuna yönelik metotlar ve bileşimler.
CN104569417B (zh) * 2013-10-12 2016-06-01 广州瑞博奥生物科技有限公司 一种用于早期诊断急性肾损伤的抗体芯片试剂盒
US10300108B2 (en) 2013-12-03 2019-05-28 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
US11243202B2 (en) 2015-04-09 2022-02-08 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
HK1249467A1 (zh) 2015-05-12 2018-11-02 阿斯图特医药公司 用於肾损伤和肾衰竭的诊断和预後的方法和组合物
EP3465201A4 (en) 2016-06-06 2020-08-26 Astute Medical, Inc. MANAGEMENT OF ACUTE KIDNEY DAMAGE USING INSULINOMIMETIC GROWTH FACTOR BINDING PROTEIN 7 AND TISSUE METALLOPROTEINASE 2 INHIBITOR
KR20210019459A (ko) 2018-05-24 2021-02-22 레니버스 테라퓨틱스, 인크. 신장 손상 및 신부전 위험이 있는 환자를 치료하는 방법
CN117825674A (zh) * 2023-12-28 2024-04-05 南方医科大学南方医院 用于评估肝病预后的分子标志物及诊断试剂盒
CN121186383B (zh) * 2025-11-24 2026-03-13 华中科技大学 慢性肾病的蛋白质标志物的筛选及应用

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
US5939272A (en) 1989-01-10 1999-08-17 Biosite Diagnostics Incorporated Non-competitive threshold ligand-receptor assays
US5028535A (en) 1989-01-10 1991-07-02 Biosite Diagnostics, Inc. Threshold ligand-receptor assay
US5922615A (en) 1990-03-12 1999-07-13 Biosite Diagnostics Incorporated Assay devices comprising a porous capture membrane in fluid-withdrawing contact with a nonabsorbent capillary network
CA2072758A1 (en) 1990-09-14 1992-03-15 Kenneth Francis Buechler Antibodies to complexes of ligand receptors and ligands and their utility in ligand-receptor assays
US5955377A (en) 1991-02-11 1999-09-21 Biostar, Inc. Methods and kits for the amplification of thin film based assays
CA2107894C (en) 1991-04-10 2003-10-14 Kenneth F. Buechler Crosstalk inhibitors and their uses
EP0579767B1 (en) 1991-04-11 2000-08-23 Biosite Diagnostics Inc. Novel conjugates and assays for simultaneous detection of multiple ligands
US6019944A (en) 1992-05-21 2000-02-01 Biosite Diagnostics, Inc. Diagnostic devices and apparatus for the controlled movement of reagents without membranes
US6143576A (en) 1992-05-21 2000-11-07 Biosite Diagnostics, Inc. Non-porous diagnostic devices for the controlled movement of reagents
US5494829A (en) 1992-07-31 1996-02-27 Biostar, Inc. Devices and methods for detection of an analyte based upon light interference
US5824799A (en) 1993-09-24 1998-10-20 Biosite Diagnostics Incorporated Hybrid phthalocyanine derivatives and their uses
US6113855A (en) 1996-11-15 2000-09-05 Biosite Diagnostics, Inc. Devices comprising multiple capillarity inducing surfaces
US5947124A (en) 1997-03-11 1999-09-07 Biosite Diagnostics Incorporated Diagnostic for determining the time of a heart attack
US6057098A (en) 1997-04-04 2000-05-02 Biosite Diagnostics, Inc. Polyvalent display libraries
CA2356174A1 (en) * 1998-12-21 2000-06-29 Monash University Kidney disease detection and treatment
WO2002048329A2 (en) * 2000-11-20 2002-06-20 Idun Pharmaceuticals, Inc. Membrane derived caspase-3, compositions comprising the same and methods of use therefor
JPWO2002081515A1 (ja) * 2001-04-03 2004-07-29 協和醗酵工業株式会社 インスリン様増殖因子結合蛋白質
US20030003588A1 (en) * 2001-06-28 2003-01-02 Comper Wayne D. Method for kidney disease detection by protein profiling
CN1791797A (zh) * 2003-03-27 2006-06-21 儿童医院医疗中心 用于检测肾小管细胞损伤的早发的方法和试剂盒
DE602004022150D1 (de) * 2003-03-27 2009-09-03 Childrens Hosp Medical Center Verfahren und kit zum nachweis des frühstadiums einer nierentubuluszellenverletzung
US7416854B2 (en) * 2004-01-22 2008-08-26 Promega Corporation Luminogenic and nonluminogenic multiplex assay
US20090215046A1 (en) * 2004-01-27 2009-08-27 Compugen Ltd. Novel nucleotide and amino acid sequences, and assays methods of use thereof for diagnosis of colon cancer
US20050272101A1 (en) * 2004-06-07 2005-12-08 Prasad Devarajan Method for the early detection of renal injury
AU2005288522B2 (en) * 2004-09-28 2012-06-28 Quark Pharmaceuticals, Inc. Oligoribonucleotides and methods of use thereof for treatment of alopecia, acute renal failure and other diseases
US7141382B1 (en) * 2004-10-12 2006-11-28 Parikh Chirag R Methods for detection of IL-18 as an early marker for diagnosis of acute renal failure and predictor of mortality
ES2818028T3 (es) * 2004-12-20 2021-04-09 Antibodyshop As Determinación de lipocalina asociada a gelatinasa de neutrófilos (NGAL) como marcador diagnóstico para trastornos renales
WO2006102979A2 (de) * 2005-03-31 2006-10-05 Johannes Gutenberg-Universität Mainz Entzündungsmarker und kombinationen davon als biochemische marker bei kardiovaskulären erkrankungen
WO2006116622A2 (en) * 2005-04-27 2006-11-02 Emiliem Novel methods and devices for evaluating poisons
TW200716764A (en) * 2005-05-02 2007-05-01 Genenews Inc Bladder cancer biomarkers and uses thereof
JP4800384B2 (ja) * 2005-06-08 2011-10-26 ヒタチ ケミカル リサーチ センター インコーポレイテッド 腫瘍細胞及び刺激された白血球におけるmRNAの発現プロファイルに基づく腫瘍性疾患に対する免疫応答を予測する方法
US7662578B2 (en) * 2006-04-21 2010-02-16 Children's Hospital Medical Center Method and kit for the early detection of impaired renal status
ATE473448T1 (de) * 2006-04-24 2010-07-15 Univ Wien Med Verfahren zur diagnose von herz-kreislauf- krankheiten
CN106908603B (zh) * 2007-01-25 2019-04-02 霍夫曼-拉罗奇有限公司 Igfbp-7在心力衰竭评估中的用途
EP2134866A2 (en) * 2007-04-10 2009-12-23 Integragen Human diabetes susceptibility tnfrsf10b gene
WO2009091556A2 (en) * 2008-01-17 2009-07-23 The General Hospital Corporation Diagnostic methods and kits using fibroblast growth factor-23
WO2010048347A2 (en) * 2008-10-21 2010-04-29 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure

Also Published As

Publication number Publication date
NZ598712A (en) 2014-05-30
WO2011025917A1 (en) 2011-03-03
US20150204892A1 (en) 2015-07-23
JP6054481B2 (ja) 2016-12-27
CN102792161A (zh) 2012-11-21
JP2015212704A (ja) 2015-11-26
EP2894473A1 (en) 2015-07-15
CN104483488A (zh) 2015-04-01
EP2470905A4 (en) 2013-08-14
JP2013503344A (ja) 2013-01-31
EP2894473B1 (en) 2016-09-21
NZ624609A (en) 2015-12-24
HK1172691A1 (en) 2013-04-26
US20120315649A1 (en) 2012-12-13
CN102792161B (zh) 2014-11-12
EP2470905B1 (en) 2015-01-07
EP3151005A1 (en) 2017-04-05
AU2010286559A1 (en) 2012-04-05
CA2772336A1 (en) 2011-03-03
EP2470905A1 (en) 2012-07-04
JP5775874B2 (ja) 2015-09-09
AU2010286559B2 (en) 2015-01-22

Similar Documents

Publication Publication Date Title
HK1208074A1 (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
HK1212764A1 (zh) 用於肾损伤和肾衰竭的诊断及预後的方法和组合物
HK1211082A1 (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
CN110702921B (zh) 用于诊断和预后肾损伤和肾衰竭的方法和组合物
HK1200218A1 (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
HK1212770A1 (zh) 用於腎損傷和腎衰竭的診斷及預後的方法和組合物
HK1220764A1 (zh) 肾损伤和肾衰竭的诊断及预後
HK1211084A1 (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
HK1204339A1 (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
HK1207155A1 (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
HK1232600A (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
HK1232600A1 (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
HK1212774B (en) Methods and composition for diagnosis and prognosis of renal injury and renal failure
HK1212774A1 (zh) 用於腎損傷和腎衰竭的診斷及預後方法和組合物
HK1172691B (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
HK1195128A (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
HK1195128B (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
HK1171261B (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
HK1203620B (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
HK1172658B (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
HK1195127A (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
HK1162617B (zh) 腎損傷和腎衰竭的診斷和預後
HK1167889B (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
HK1203620A1 (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
HK1167888B (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure