HK1208054A1 - Mesenchymal-like stem cells derived from human embryonic stem cells, methods and uses thereof - Google Patents

Mesenchymal-like stem cells derived from human embryonic stem cells, methods and uses thereof

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Publication number
HK1208054A1
HK1208054A1 HK15108691.8A HK15108691A HK1208054A1 HK 1208054 A1 HK1208054 A1 HK 1208054A1 HK 15108691 A HK15108691 A HK 15108691A HK 1208054 A1 HK1208054 A1 HK 1208054A1
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HK
Hong Kong
Prior art keywords
stem cells
mesenchymal
methods
human embryonic
embryonic stem
Prior art date
Application number
HK15108691.8A
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English (en)
Chinese (zh)
Inventor
王小方
徐仁和
Original Assignee
Imstem Biotechnology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49916651&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1208054(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Imstem Biotechnology Inc filed Critical Imstem Biotechnology Inc
Publication of HK1208054A1 publication Critical patent/HK1208054A1/xx

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    • C—CHEMISTRY; METALLURGY
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/51—Umbilical cord; Umbilical cord blood; Umbilical stem cells
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/069—Vascular Endothelial cells
    • C12N5/0692—Stem cells; Progenitor cells; Precursor cells
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
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    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/90—Substrates of biological origin, e.g. extracellular matrix, decellularised tissue

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  • Health & Medical Sciences (AREA)
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  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
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  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Rheumatology (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • Reproductive Health (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
HK15108691.8A 2012-07-12 2015-09-07 Mesenchymal-like stem cells derived from human embryonic stem cells, methods and uses thereof HK1208054A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261670787P 2012-07-12 2012-07-12
US201361762961P 2013-02-11 2013-02-11
PCT/US2013/048291 WO2014011407A2 (en) 2012-07-12 2013-06-27 Mesenchymal-like stem cells derived from human embryonic stem cells, methods and uses thereof

Publications (1)

Publication Number Publication Date
HK1208054A1 true HK1208054A1 (en) 2016-02-19

Family

ID=49916651

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15108691.8A HK1208054A1 (en) 2012-07-12 2015-09-07 Mesenchymal-like stem cells derived from human embryonic stem cells, methods and uses thereof

Country Status (5)

Country Link
US (3) US9745551B2 (xx)
CN (1) CN104471059B (xx)
CA (1) CA2876499C (xx)
HK (1) HK1208054A1 (xx)
WO (1) WO2014011407A2 (xx)

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JP6114840B2 (ja) * 2013-03-01 2017-04-12 アプセト ゲーエムベーハー アンド ツェーオー．カーゲー ヒトｃｄ３４陰性前駆細胞による免疫に媒介される細胞傷害性反応からの血管内皮の保護
EP3105587B1 (en) * 2014-02-11 2023-09-06 Brainstorm Cell Therapeutics Ltd. Method of qualifying cells
WO2015198144A2 (en) 2014-06-27 2015-12-30 Techflux, Ltd. Method and device for transmitting data unit
WO2016065245A1 (en) * 2014-10-24 2016-04-28 Incept, Llc Extra luminal scaffold
CN105769911A (zh) * 2016-03-23 2016-07-20 中国人民解放军第二军医大学 间充质干细胞诱导斑秃处毛发再生的方法及应用
JP2020509773A (ja) * 2017-03-17 2020-04-02 センティ バイオサイエンシズ インコーポレイテッド 免疫調節性細胞回路
CN110996975A (zh) 2017-04-13 2020-04-10 森迪生物科学公司 组合癌症免疫疗法
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WO2019053295A1 (en) * 2017-09-18 2019-03-21 Fundació Institut D'investigació Sanitària Pere Virgili METHODS FOR IMPROVING THE EFFICACY OF CELL THERAPY WITH MESENCHYMAL STEM CELL POPULATIONS
CN109666630A (zh) * 2017-10-17 2019-04-23 澳门大学 多能干细胞分化为间充质干细胞的方法及其培养基和应用
JP7306635B2 (ja) * 2017-11-09 2023-07-11 北海道公立大学法人 札幌医科大学 組織再生用医薬及びその製造方法
WO2019104466A1 (en) * 2017-11-28 2019-06-06 Harvatek Corporation Methods of producing populations of mesenchymal stem cells from peripheral blood and uses thereof
KR102096150B1 (ko) * 2018-01-05 2020-04-02 재단법인 아산사회복지재단 인터페론 감마로 전처리된 유도만능 줄기세포 유래 중간엽 줄기세포 및 이로부터 유래된 엑소좀을 포함하는 피부질환의 개선, 예방 또는 치료용 조성물
CN108646030B (zh) * 2018-06-04 2020-12-22 中国医学科学院北京协和医院 一种大动脉炎检测的生物标志物面板及其用途
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JP2022542247A (ja) * 2019-07-24 2022-09-30 エスエルバイジェン インコ―ポレイテッド 不死化幹細胞株の製造方法およびその用途
EP3909594A1 (en) * 2020-05-14 2021-11-17 Bernat Soria Escoms Mesenchymal stromal cells for the treatment of covid-19 and other inflammatory, autoimmune and degenerative diseases
CN111979187B (zh) * 2020-08-21 2022-04-08 遵义医科大学附属医院 一种抗人间充质干细胞衰老及增强其干性特征的方法
CN114457033A (zh) * 2020-10-30 2022-05-10 未来智人再生医学研究院(广州)有限公司 一种表达il-6阻断物的多能干细胞衍生物及其应用
CN112748080A (zh) * 2020-12-25 2021-05-04 北京泽辉辰星生物科技有限公司 满足产品放行要求的免疫调节干细胞ido1活性检测方法
CN114752688B (zh) * 2022-04-28 2024-02-23 北京大学口腔医学院 鉴定人类胚胎骨髓来源的间充质干细胞的方法、探针和试剂盒及其用途
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Publication number Publication date
US20200392463A1 (en) 2020-12-17
WO2014011407A2 (en) 2014-01-16
CA2876499C (en) 2021-10-26
CN104471059A (zh) 2015-03-25
US20180010098A1 (en) 2018-01-11
CA2876499A1 (en) 2014-01-16
US20150203820A1 (en) 2015-07-23
CN104471059B (zh) 2018-04-17
WO2014011407A3 (en) 2014-04-17
US10557122B2 (en) 2020-02-11
US9745551B2 (en) 2017-08-29

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