HK1214624A1 - 心臟幹細胞和其識別方法和用途 - Google Patents

心臟幹細胞和其識別方法和用途

Info

Publication number
HK1214624A1
HK1214624A1 HK16102542.1A HK16102542A HK1214624A1 HK 1214624 A1 HK1214624 A1 HK 1214624A1 HK 16102542 A HK16102542 A HK 16102542A HK 1214624 A1 HK1214624 A1 HK 1214624A1
Authority
HK
Hong Kong
Prior art keywords
identifying
methods
same
stem cells
cardiac stem
Prior art date
Application number
HK16102542.1A
Other languages
English (en)
Inventor
E Hatzistergos Konstantinos
M Hare Joshua
Original Assignee
Vestion Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vestion Inc filed Critical Vestion Inc
Publication of HK1214624A1 publication Critical patent/HK1214624A1/zh

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/34Muscles; Smooth muscle cells; Heart; Cardiac stem cells; Myoblasts; Myocytes; Cardiomyocytes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/02Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0657Cardiomyocytes; Heart cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662Stem cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5073Stem cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/02Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
HK16102542.1A 2012-11-30 2016-03-07 心臟幹細胞和其識別方法和用途 HK1214624A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261731835P 2012-11-30 2012-11-30
PCT/US2013/072660 WO2014093051A2 (en) 2012-11-30 2013-12-02 Cardiac stem cells and methods of identifying and using the same

Publications (1)

Publication Number Publication Date
HK1214624A1 true HK1214624A1 (zh) 2016-07-29

Family

ID=50935070

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16102542.1A HK1214624A1 (zh) 2012-11-30 2016-03-07 心臟幹細胞和其識別方法和用途

Country Status (6)

Country Link
US (3) US9746457B2 (zh)
EP (1) EP2925863B1 (zh)
JP (2) JP7042017B2 (zh)
ES (1) ES2824165T3 (zh)
HK (1) HK1214624A1 (zh)
WO (1) WO2014093051A2 (zh)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9962409B2 (en) 2007-10-01 2018-05-08 Vestion, Inc. Therapy using cardiac stem cells and mesenchymal stem cells
US9657290B2 (en) 2012-07-03 2017-05-23 The Board Of Trustees Of The Leland Stanford Junior University Scalable bio-element analysis
ES2824165T3 (es) 2012-11-30 2021-05-11 Vestion Inc Células madre cardíacas y métodos de identificación y uso de las mismas
US10786536B2 (en) 2013-10-29 2020-09-29 Vestion, Inc. Cardiac neural crest cells and methods of use thereof
EP3259346A4 (en) * 2015-02-20 2018-07-11 Baylor College of Medicine P63 inactivation for the treatment of heart failure
US10613078B2 (en) 2015-02-20 2020-04-07 Ncardia B.V. Assays for measuring cardiotoxicity
US10370653B2 (en) 2015-02-22 2019-08-06 The Board Of Trustees Of The Leland Stanford Junior University Micro-screening apparatus, process, and products
JP6703824B2 (ja) * 2015-11-30 2020-06-03 シスメックス株式会社 細胞選択方法、細胞検出方法、細胞選択装置、および細胞検出装置
CN115254210A (zh) 2016-11-14 2022-11-01 浩康生物系统公司 用于分选目标颗粒的方法和装置
IT201700062176A1 (it) * 2017-06-07 2018-12-07 Univ Degli Studi Milano Metodo per l’isolamento di sottopopolazioni di progenitori cellulari cardiaci e relativi usi in campo medico
CA3153845A1 (en) * 2019-10-09 2021-04-15 Rickey REINHARDT Epicardial delivery of gene therapy

Family Cites Families (19)

* Cited by examiner, † Cited by third party
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DK1007631T4 (da) 1997-07-14 2009-04-27 Osiris Therapeutics Inc Hjertemuskelregeneration ved anvendelse af mesenkymale stamceller
US6821740B2 (en) * 1998-02-25 2004-11-23 Becton, Dickinson And Company Flow cytometric methods for the concurrent detection of discrete functional conformations of PRB in single cells
DE69937888T2 (de) 1998-07-31 2009-01-02 Genzyme Corp., Cambridge Verfahren zur Herstellung mesenchymaler Stammzellen
US8075881B2 (en) 1999-08-05 2011-12-13 Regents Of The University Of Minnesota Use of multipotent adult stem cells in treatment of myocardial infarction and congestive heart failure
US7547674B2 (en) 2001-06-06 2009-06-16 New York Medical College Methods and compositions for the repair and/or regeneration of damaged myocardium
US6930222B2 (en) 2000-08-22 2005-08-16 The Scripps Research Institute In vivo animal model of human leukemia
WO2004019767A2 (en) 2002-08-29 2004-03-11 Baylor College Of Medicine Heart derived cells for cardiac repair
AU2004247157A1 (en) 2003-06-12 2004-12-23 Regents Of The University Of Minnesota Directing cells to target tissues or organs
US7082573B2 (en) 2003-07-30 2006-07-25 America Online, Inc. Method and system for managing digital assets
EP1674562A4 (en) 2003-10-03 2007-04-11 Keiichi Fukuda METHOD OF INDUCING DIFFERENTIATION OF STEM CELLS INTO MYOCARDIAL CELLS
DE602004024125D1 (de) 2003-12-25 2009-12-24 Kanazawa University Technology Induktion einer myokardzelle unter verwendung einer säuger-knochenmarkzelle oder aus nabelschnurblut stammenden zelle und fettgewebe
WO2006039630A2 (en) 2004-10-02 2006-04-13 Indiana University Research & Technology Corporation Materials and methods for identifying compounds that modulate the cell cycle
US20100166714A1 (en) 2006-11-02 2010-07-01 The General Hospital Corporation Cardiovascular stem cells, methods for stem cell isolation, and uses thereof
EP2079831A2 (en) * 2006-11-07 2009-07-22 Keck Graduate Institute Enriched stem cell and progenitor cell populations, and methods of producing and using such populations
US9962409B2 (en) 2007-10-01 2018-05-08 Vestion, Inc. Therapy using cardiac stem cells and mesenchymal stem cells
US8512696B2 (en) * 2007-11-30 2013-08-20 Autologous, Llc Methods of isolating non-senescent cardiac stem cells and uses thereof
CA2802526C (en) 2010-06-13 2021-11-16 Institute Of Biophysics, Chinese Academy Of Sciences Methods and compositions for preparing cardiomyocytes from stem cells and uses thereof
ES2824165T3 (es) 2012-11-30 2021-05-11 Vestion Inc Células madre cardíacas y métodos de identificación y uso de las mismas
US10786536B2 (en) 2013-10-29 2020-09-29 Vestion, Inc. Cardiac neural crest cells and methods of use thereof

Also Published As

Publication number Publication date
US20200166498A1 (en) 2020-05-28
EP2925863A2 (en) 2015-10-07
US20150316535A1 (en) 2015-11-05
EP2925863B1 (en) 2020-07-15
ES2824165T3 (es) 2021-05-11
US20180180592A1 (en) 2018-06-28
US9746457B2 (en) 2017-08-29
EP2925863A4 (en) 2016-04-13
JP7042017B2 (ja) 2022-03-29
WO2014093051A3 (en) 2014-08-21
JP2020096595A (ja) 2020-06-25
WO2014093051A2 (en) 2014-06-19
JP2016504021A (ja) 2016-02-12
US10481147B2 (en) 2019-11-19

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