HK1208048A1 - Cyaa-based chimeric proteins comprising a heterologous polypeptide and their uses in the induction of immune responses cyaa - Google Patents
Cyaa-based chimeric proteins comprising a heterologous polypeptide and their uses in the induction of immune responses cyaaInfo
- Publication number
- HK1208048A1 HK1208048A1 HK15108580.2A HK15108580A HK1208048A1 HK 1208048 A1 HK1208048 A1 HK 1208048A1 HK 15108580 A HK15108580 A HK 15108580A HK 1208048 A1 HK1208048 A1 HK 1208048A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- cyaa
- induction
- immune responses
- heterologous polypeptide
- chimeric proteins
- Prior art date
Links
- 102000037865 fusion proteins Human genes 0.000 title 1
- 108020001507 fusion proteins Proteins 0.000 title 1
- 230000028993 immune response Effects 0.000 title 1
- 230000006698 induction Effects 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/235—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bordetella (G)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y406/00—Phosphorus-oxygen lyases (4.6)
- C12Y406/01—Phosphorus-oxygen lyases (4.6.1)
- C12Y406/01001—Aodenylate cyclase (4.6.1.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
- A61K2039/585—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation wherein the target is cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP12305897.6A EP2690172A1 (en) | 2012-07-23 | 2012-07-23 | CYAA-based chimeric proteins comprising a heterologous polypeptide and their uses in the induction of immune responses |
PCT/EP2013/065546 WO2014016310A1 (en) | 2012-07-23 | 2013-07-23 | Cyaa-based chimeric proteins comprising a heterologous polypeptide and their uses in the induction of immune responses |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1208048A1 true HK1208048A1 (en) | 2016-02-19 |
Family
ID=48832934
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK15108580.2A HK1208048A1 (en) | 2012-07-23 | 2015-09-02 | Cyaa-based chimeric proteins comprising a heterologous polypeptide and their uses in the induction of immune responses cyaa |
Country Status (13)
Country | Link |
---|---|
US (2) | US9499809B2 (ja) |
EP (2) | EP2690172A1 (ja) |
JP (3) | JP2015524270A (ja) |
KR (1) | KR102148413B1 (ja) |
CN (1) | CN104662152B (ja) |
AU (1) | AU2013295045B2 (ja) |
BR (1) | BR112015001350A2 (ja) |
CA (1) | CA2879990C (ja) |
ES (1) | ES2780525T3 (ja) |
HK (1) | HK1208048A1 (ja) |
MX (1) | MX365560B (ja) |
RU (1) | RU2015100211A (ja) |
WO (1) | WO2014016310A1 (ja) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105481953B (zh) * | 2016-02-02 | 2018-02-13 | 成都天邦生物制品有限公司 | 作为猪繁殖与呼吸综合征病毒疫苗抗原的靶细胞特异性融合蛋白和疫苗组合物 |
EP3323426A1 (en) | 2016-11-17 | 2018-05-23 | Ecole Nationale Vétérinaire de Toulouse | Immunogenic and vaccine compositions for use against bordetella bronchiseptica infection |
WO2018091613A1 (en) | 2016-11-17 | 2018-05-24 | Ecole Nationale Vétérinaire de Toulouse | Immunogenic and vaccine compositions for use against bordetella bronchiseptica infection |
EP3323424A1 (en) * | 2016-11-17 | 2018-05-23 | Cyanimal IP | Cyaa polypeptides as immune enhancer |
EP3342421A1 (en) * | 2016-12-27 | 2018-07-04 | Genticel | Immunogenic composition comprising cyaa-derived polypeptide promoting a th1/th17-oriented immune response |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH01209817A (ja) | 1988-02-17 | 1989-08-23 | Yamaha Corp | 浮動少数点形ディジタル・アナログ変換器 |
ES2331348T3 (es) | 2000-09-15 | 2009-12-30 | Pasteur Institut | Vectores proteinicos para el suministro de moleculas a las celulas que expresan cd11b. |
EP1489092A1 (en) | 2003-06-18 | 2004-12-22 | Institut Pasteur | Modified Bordetella adenylate cyclase comprising or lacking CD11b/CD18 interaction domain and uses thereof |
ATE450272T1 (de) | 2003-11-21 | 2009-12-15 | Pasteur Institut | Rekombinantes adenylat-cyclase-toxin von bordetella induziert t-zell-antworten gegen tumorale antigene |
DK1576967T3 (da) | 2004-03-18 | 2008-01-21 | Pasteur Institut | Rekombinant protein, der bærer epitoper fra det humane papillomvirus indsat i et adenylatcyclaseprotein eller et fragment deraf samt dets terapeutiske anvendelse |
EP1894941A1 (en) | 2006-09-01 | 2008-03-05 | Institut Pasteur | Treatment of cervical carcinoma with a recombinant adenylate cyclase carrying HPV antigens |
RU2448729C2 (ru) | 2006-09-01 | 2012-04-27 | Жантисель | Композиции, вызывающие специфический ответ цитотоксических т-лимфоцитов, включающие лимфо-аблативное соединение и молекулу, содержащую антигенные последовательности и нацеленную на специализированные антиген-презентирующие клетки |
CN102159948B (zh) * | 2008-07-22 | 2014-06-25 | 普罗美加公司 | 基于adp检测的发光磷酸转移酶或atp水解酶测定 |
CN105602924A (zh) * | 2009-03-23 | 2016-05-25 | 巴斯德研究院 | 适合将免疫原性分子递送到细胞中的突变CyaA多肽及多肽衍生物 |
EP2478915A1 (en) | 2011-01-24 | 2012-07-25 | Genticel | CyaA-carried polypeptide(s) and use to induce both therapeutic and prophylactic immune responses |
EP2689786A1 (en) * | 2012-07-23 | 2014-01-29 | Genticel | HPV/CYAA-based chimeric proteins and their uses in the induction of immune responses against HPV infection and HPV-induced disorders |
-
2012
- 2012-07-23 EP EP12305897.6A patent/EP2690172A1/en not_active Withdrawn
-
2013
- 2013-07-23 RU RU2015100211A patent/RU2015100211A/ru unknown
- 2013-07-23 MX MX2015001018A patent/MX365560B/es active IP Right Grant
- 2013-07-23 WO PCT/EP2013/065546 patent/WO2014016310A1/en active Application Filing
- 2013-07-23 US US14/416,569 patent/US9499809B2/en active Active
- 2013-07-23 KR KR1020157004541A patent/KR102148413B1/ko active IP Right Grant
- 2013-07-23 JP JP2015523535A patent/JP2015524270A/ja active Pending
- 2013-07-23 EP EP13739724.6A patent/EP2875130B1/en active Active
- 2013-07-23 BR BR112015001350A patent/BR112015001350A2/pt not_active Application Discontinuation
- 2013-07-23 AU AU2013295045A patent/AU2013295045B2/en active Active
- 2013-07-23 CA CA2879990A patent/CA2879990C/en active Active
- 2013-07-23 ES ES13739724T patent/ES2780525T3/es active Active
- 2013-07-23 CN CN201380049494.6A patent/CN104662152B/zh not_active Expired - Fee Related
-
2015
- 2015-09-02 HK HK15108580.2A patent/HK1208048A1/xx unknown
-
2016
- 2016-10-12 US US15/291,517 patent/US9982024B2/en active Active
-
2018
- 2018-09-06 JP JP2018166486A patent/JP2019013229A/ja active Pending
-
2021
- 2021-12-23 JP JP2021208859A patent/JP2022046617A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
US9982024B2 (en) | 2018-05-29 |
US20150184143A1 (en) | 2015-07-02 |
RU2015100211A3 (ja) | 2018-12-20 |
CN104662152A (zh) | 2015-05-27 |
CN104662152B (zh) | 2020-06-12 |
EP2875130A1 (en) | 2015-05-27 |
BR112015001350A2 (pt) | 2017-08-01 |
JP2019013229A (ja) | 2019-01-31 |
AU2013295045B2 (en) | 2019-05-02 |
EP2690172A1 (en) | 2014-01-29 |
AU2013295045A1 (en) | 2015-02-05 |
US9499809B2 (en) | 2016-11-22 |
CA2879990C (en) | 2021-11-16 |
JP2015524270A (ja) | 2015-08-24 |
KR20150032341A (ko) | 2015-03-25 |
JP2022046617A (ja) | 2022-03-23 |
CA2879990A1 (en) | 2014-01-30 |
KR102148413B1 (ko) | 2020-08-26 |
EP2875130B1 (en) | 2020-01-01 |
WO2014016310A1 (en) | 2014-01-30 |
RU2015100211A (ru) | 2018-12-20 |
MX365560B (es) | 2019-06-07 |
MX2015001018A (es) | 2015-07-14 |
ES2780525T3 (es) | 2020-08-26 |
US20170096458A1 (en) | 2017-04-06 |
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