HK1207322A1 - Injectable silk fibroin particles and uses thereof - Google Patents
Injectable silk fibroin particles and uses thereofInfo
- Publication number
- HK1207322A1 HK1207322A1 HK15107915.0A HK15107915A HK1207322A1 HK 1207322 A1 HK1207322 A1 HK 1207322A1 HK 15107915 A HK15107915 A HK 15107915A HK 1207322 A1 HK1207322 A1 HK 1207322A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- silk fibroin
- fibroin particles
- injectable silk
- injectable
- particles
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/0059—Cosmetic or alloplastic implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3834—Cells able to produce different cell types, e.g. hematopoietic stem cells, mesenchymal stem cells, marrow stromal cells, embryonic stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
- A61L27/48—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with macromolecular fillers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/58—Materials at least partially resorbable by the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/06—Flowable or injectable implant compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/34—Materials or treatment for tissue regeneration for soft tissue reconstruction
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Urology & Nephrology (AREA)
- Zoology (AREA)
- Botany (AREA)
- Cell Biology (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dispersion Chemistry (AREA)
- Developmental Biology & Embryology (AREA)
- Hematology (AREA)
- Materials Engineering (AREA)
- Composite Materials (AREA)
- Physical Education & Sports Medicine (AREA)
- Reproductive Health (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Neurology (AREA)
- Endocrinology (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161557603P | 2011-11-09 | 2011-11-09 | |
PCT/US2012/064450 WO2013071107A1 (en) | 2011-11-09 | 2012-11-09 | Injectable silk fibroin particles and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1207322A1 true HK1207322A1 (en) | 2016-01-29 |
Family
ID=48290608
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK15107915.0A HK1207322A1 (en) | 2011-11-09 | 2015-08-17 | Injectable silk fibroin particles and uses thereof |
Country Status (12)
Country | Link |
---|---|
US (3) | US9931434B2 (xx) |
EP (2) | EP2788040B1 (xx) |
JP (2) | JP6362540B2 (xx) |
KR (3) | KR20230066481A (xx) |
CN (1) | CN104363931A (xx) |
AU (2) | AU2012335106B2 (xx) |
BR (1) | BR112014011188B1 (xx) |
CA (1) | CA2890366A1 (xx) |
ES (1) | ES2953309T3 (xx) |
HK (1) | HK1207322A1 (xx) |
MX (1) | MX2014005702A (xx) |
WO (1) | WO2013071107A1 (xx) |
Families Citing this family (35)
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CN104363931A (zh) | 2011-11-09 | 2015-02-18 | 塔夫茨大学信托人 | 可注射丝素蛋白粒子及其用途 |
WO2013152265A1 (en) | 2012-04-06 | 2013-10-10 | Trustees Of Tufts College | Methods of producing and using silk microfibers |
US11376329B2 (en) | 2013-03-15 | 2022-07-05 | Trustees Of Tufts College | Low molecular weight silk compositions and stabilizing silk compositions |
CN103357066B (zh) * | 2013-06-28 | 2015-07-29 | 陕西巨子生物技术有限公司 | 一种具有生物修复活性及优良降解性能的水凝胶及制备方法 |
US20150290248A1 (en) * | 2014-04-10 | 2015-10-15 | Nanofiber Health, Inc. | Fibrous component for health, performance, and aesthetic treatment |
EP3180042A4 (en) * | 2014-08-15 | 2018-02-28 | The Johns Hopkins University Technology Ventures | Composite material for tissue restoration |
GB201415681D0 (en) | 2014-09-04 | 2014-10-22 | Cambridge Entpr Ltd And President And Fellows Of Harvard College | Protien Capsules |
JP6946187B2 (ja) | 2014-12-02 | 2021-10-06 | エボルブド バイ ネイチャー, インコーポレイテッド | シルク性能衣服及び製品、並びにこれらを製造する方法 |
CN108135975A (zh) | 2015-07-14 | 2018-06-08 | 丝绸医疗公司 | 丝性能服装和产品及其制备方法 |
GB201514788D0 (en) * | 2015-08-20 | 2015-10-07 | Ecole Polytech | Malleable scaffold material and uses thereof |
KR101710639B1 (ko) * | 2016-06-07 | 2017-03-08 | 주식회사 파마리서치프로덕트 | 핵산, 키토산 및 히알루론산을 포함하는 조직 증강용 충전 조성물 및 이의 제조방법 |
WO2018081805A1 (en) * | 2016-10-31 | 2018-05-03 | Sofregen Medical, Inc. | Compositions comprising low molecular weight silk fibroin fragments and plasticizers |
EP3548114A4 (en) | 2016-12-28 | 2020-07-15 | SanBio, Inc. | CELL RELEASE SYSTEM AND METHOD FOR THE OPERATION THEREOF |
CN106729982A (zh) * | 2016-12-29 | 2017-05-31 | 浙江大学 | 一种丝素蛋白纳米球的制备方法 |
JP6482604B2 (ja) * | 2017-06-22 | 2019-03-13 | 教裕 南郷 | 外皮内溶解型ニードル及びニードル装置 |
CN111712514A (zh) | 2017-09-27 | 2020-09-25 | 自然进化公司 | 丝涂布织物和产品及其制备方法 |
CN111201046B (zh) * | 2017-10-18 | 2022-06-28 | 生命细胞公司 | 脂肪组织产品以及产生方法 |
RU2683557C1 (ru) * | 2017-11-22 | 2019-03-28 | Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр трансплантологии и искусственных органов имени академика В.И. Шумакова" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ ТИО им. ак. В.И. Шумакова" Минздрава России) | Способ получения биодеградируемых скаффолдов из фиброина шелка с улучшенными биологическими свойствами |
RU2684769C1 (ru) * | 2017-11-22 | 2019-04-12 | Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр трансплантологии и искусственных органов имени академика В.И. Шумакова" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ ТИО им. ак. В.И. Шумакова" Минздрава России) | Композиция для изготовления биодеградируемых скаффолдов и способ ее получения |
WO2019139380A1 (ko) * | 2018-01-10 | 2019-07-18 | 주식회사 지투지바이오 | 비타민 c가 함유된 폴리카프로락톤 미립구 필러 및 그 제조방법 |
EP3765103A1 (en) | 2018-03-12 | 2021-01-20 | Merz Pharma GmbH & Co. KGaA | Porous biomaterials for tissue regeneration |
AU2019267711A1 (en) | 2018-05-09 | 2020-12-03 | The Johns Hopkins University | Nanofiber-hydrogel composites for cell and tissue delivery |
CN109851819B (zh) * | 2019-03-08 | 2021-10-29 | 江西丝科生物科技有限公司 | 一种可注射丝素蛋白多孔水凝胶及其制备方法 |
DE112020002263T5 (de) * | 2019-05-07 | 2022-01-20 | Preco, Inc. | Umschließungsabschlussverfahren zum Umschließen von lockerem Material und umschlossenes lockeres Material |
WO2020247594A1 (en) | 2019-06-04 | 2020-12-10 | Cocoon Biotech Inc. | Silk-based products, formulations, and methods of use |
CN110384823B (zh) * | 2019-07-19 | 2021-08-03 | 大连医科大学 | 基于丝素蛋白支架的仿生肝小叶及构建方法 |
CN117120594A (zh) * | 2020-11-12 | 2023-11-24 | 塔夫茨大学托管会 | 培养的脂肪组织 |
US20240033401A1 (en) * | 2020-12-18 | 2024-02-01 | Drexel University | Injectable, cross-linkable and subcellular size microfibers for soft tissue repair |
CN112587721A (zh) * | 2020-12-30 | 2021-04-02 | 广州益诚生物科技有限公司 | 一种注射填充材料及制备工艺 |
CN113069593A (zh) * | 2021-04-10 | 2021-07-06 | 中国人民解放军总医院 | 预混氏干细胞分泌蛋白组丝素水凝胶的制作工艺 |
WO2022232090A2 (en) * | 2021-04-29 | 2022-11-03 | Carnegie Mellon University | Acoustically responsive biomaterials |
WO2023097310A1 (en) * | 2021-11-29 | 2023-06-01 | Massachusetts Institute Of Technology | Tunable structure of biodegradable silk-based microcapsules for soluble and insoluble payload delivery |
CN115105645B (zh) * | 2022-06-28 | 2023-05-26 | 北京化工大学 | 一种复合微球、伤口修复敷料的制备方法 |
WO2024119107A1 (en) * | 2022-12-01 | 2024-06-06 | Evolved By Nature, Inc. | Lyophilized and sprayable silk fibroin and modified silk fibroin forms |
CN116554507B (zh) * | 2023-07-12 | 2023-09-29 | 江西丝科生物科技有限公司 | 蚕丝蛋白双网络水凝胶及其制备方法 |
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KR100894265B1 (ko) * | 2007-06-05 | 2009-04-21 | 재단법인서울대학교산학협력재단 | 골형성 촉진 펩타이드를 함유하는 주입형 골재생재 |
JP2011504421A (ja) | 2007-11-05 | 2011-02-10 | トラスティーズ オブ タフツ カレッジ | ナノコンタクトインプリンティングによる絹フィブロインフォトニック構造の作製 |
CA2711001A1 (en) * | 2007-12-26 | 2009-07-09 | Gel-Del Technologies, Inc. | Biocompatible protein-based particles and methods thereof |
CN101970023A (zh) | 2008-02-07 | 2011-02-09 | 塔夫茨大学信托人 | 三维的丝羟基磷灰石组合物 |
US8206774B2 (en) | 2008-03-13 | 2012-06-26 | Trustees Of Tufts College | Diazonium salt modification of silk polymer |
WO2009126689A2 (en) | 2008-04-08 | 2009-10-15 | Trustees Of Tufts College | System and method for making biomaterial structures |
JP2011525254A (ja) | 2008-06-18 | 2011-09-15 | トラスティーズ オブ タフツ カレッジ | 食用のホログラフィック絹製品 |
JP5896743B2 (ja) | 2008-10-09 | 2016-03-30 | タフツ ユニバーシティー/トラスティーズ オブ タフツ カレッジ | グリセロールを含有する改変された絹フィルム |
US9427499B2 (en) | 2008-11-17 | 2016-08-30 | Trustees Of Tufts College | Surface modification of silk fibroin matrices with poly(ethylene glycol) useful as anti-adhesion barriers and anti-thrombotic materials |
ES2423055T3 (es) * | 2009-04-20 | 2013-09-17 | Allergan, Inc. | Hidrogeles de fibroína de seda y usos de éstos |
US20110189292A1 (en) * | 2009-04-20 | 2011-08-04 | Allergan, Inc. | Dermal fillers comprising silk fibroin hydrogels and uses thereof |
WO2011005381A2 (en) | 2009-06-01 | 2011-01-13 | Trustees Of Tufts College | Vortex-induced silk fibroin gelation for encapsulation and delivery |
AU2010271238A1 (en) | 2009-07-10 | 2012-02-09 | Trustees Of Tufts College | Bioengineered silk protein-based nucleic acid delivery systems |
WO2011011347A2 (en) | 2009-07-21 | 2011-01-27 | Trustees Of Tufts College | Functionalization of silk material by avidin-biotin interaction |
CN102188753B (zh) * | 2011-05-10 | 2013-10-09 | 中原工学院 | 一种含有柞蚕丝素的纳米骨仿生材料及其制备方法 |
CN104363931A (zh) | 2011-11-09 | 2015-02-18 | 塔夫茨大学信托人 | 可注射丝素蛋白粒子及其用途 |
EP3750567A1 (en) * | 2011-11-09 | 2020-12-16 | Trustees of Tufts College | Injectable silk fibroin foams and uses thereof |
-
2012
- 2012-11-09 CN CN201280066536.2A patent/CN104363931A/zh active Pending
- 2012-11-09 WO PCT/US2012/064450 patent/WO2013071107A1/en active Application Filing
- 2012-11-09 KR KR1020237014603A patent/KR20230066481A/ko not_active Application Discontinuation
- 2012-11-09 EP EP12846915.2A patent/EP2788040B1/en active Active
- 2012-11-09 AU AU2012335106A patent/AU2012335106B2/en active Active
- 2012-11-09 CA CA2890366A patent/CA2890366A1/en not_active Abandoned
- 2012-11-09 EP EP23168344.2A patent/EP4257202A3/en active Pending
- 2012-11-09 US US14/357,443 patent/US9931434B2/en active Active
- 2012-11-09 BR BR112014011188A patent/BR112014011188B1/pt active IP Right Grant
- 2012-11-09 JP JP2014541327A patent/JP6362540B2/ja active Active
- 2012-11-09 KR KR1020207021207A patent/KR20200093073A/ko not_active IP Right Cessation
- 2012-11-09 KR KR1020147015500A patent/KR102138152B1/ko active IP Right Grant
- 2012-11-09 MX MX2014005702A patent/MX2014005702A/es unknown
- 2012-11-09 ES ES12846915T patent/ES2953309T3/es active Active
-
2015
- 2015-08-17 HK HK15107915.0A patent/HK1207322A1/xx unknown
-
2016
- 2016-11-23 AU AU2016262684A patent/AU2016262684A1/en not_active Abandoned
-
2017
- 2017-12-28 JP JP2017252933A patent/JP2018089388A/ja active Pending
-
2018
- 2018-02-20 US US15/899,463 patent/US20180339084A1/en not_active Abandoned
-
2020
- 2020-11-06 US US17/091,835 patent/US20210244850A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
EP4257202A2 (en) | 2023-10-11 |
US20140308362A1 (en) | 2014-10-16 |
KR20230066481A (ko) | 2023-05-15 |
AU2012335106A1 (en) | 2014-06-26 |
JP2015502199A (ja) | 2015-01-22 |
EP4257202A3 (en) | 2023-12-20 |
US20180339084A1 (en) | 2018-11-29 |
US20210244850A1 (en) | 2021-08-12 |
KR102138152B1 (ko) | 2020-07-27 |
BR112014011188A2 (pt) | 2017-05-09 |
JP2018089388A (ja) | 2018-06-14 |
EP2788040A1 (en) | 2014-10-15 |
CN104363931A (zh) | 2015-02-18 |
ES2953309T3 (es) | 2023-11-10 |
KR20140102208A (ko) | 2014-08-21 |
CA2890366A1 (en) | 2013-05-16 |
JP6362540B2 (ja) | 2018-07-25 |
MX2014005702A (es) | 2015-02-17 |
BR112014011188A8 (pt) | 2018-05-29 |
AU2012335106B2 (en) | 2016-09-01 |
US9931434B2 (en) | 2018-04-03 |
EP2788040A4 (en) | 2015-05-06 |
EP2788040B1 (en) | 2023-05-24 |
WO2013071107A1 (en) | 2013-05-16 |
AU2016262684A1 (en) | 2016-12-15 |
BR112014011188B1 (pt) | 2020-05-19 |
KR20200093073A (ko) | 2020-08-04 |
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