HK1206759A1 - Anti-hcmv idiotypic antibodies and uses thereof -hcmv - Google Patents

Anti-hcmv idiotypic antibodies and uses thereof -hcmv

Info

Publication number
HK1206759A1
HK1206759A1 HK15107419.1A HK15107419A HK1206759A1 HK 1206759 A1 HK1206759 A1 HK 1206759A1 HK 15107419 A HK15107419 A HK 15107419A HK 1206759 A1 HK1206759 A1 HK 1206759A1
Authority
HK
Hong Kong
Prior art keywords
hcmv
idiotypic antibodies
idiotypic
antibodies
hcmv idiotypic
Prior art date
Application number
HK15107419.1A
Other languages
English (en)
Chinese (zh)
Inventor
Jo-Anne Hongo
Keyang Xu
Mauricio Maia
Rajesh Vij
Terence Wong
John Lowe
Yanhong Li
Luna Liu
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of HK1206759A1 publication Critical patent/HK1206759A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4208Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
    • C07K16/4216Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-viral Ig
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/081Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
    • C07K16/085Herpetoviridae, e.g. pseudorabies virus, Epstein-Barr virus
    • C07K16/089Cytomegalovirus
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983Viruses
    • G01N33/56994Herpetoviridae, e.g. cytomegalovirus, Epstein-Barr virus
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • G01N33/686Anti-idiotype
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/01DNA viruses
    • G01N2333/03Herpetoviridae, e.g. pseudorabies virus
    • G01N2333/04Varicella-zoster virus
    • G01N2333/045Cytomegalovirus
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00Immunoassays for the detection of microorganisms
    • G01N2469/20Detection of antibodies in sample from host which are directed against antigens from microorganisms

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Peptides Or Proteins (AREA)
HK15107419.1A 2012-03-28 2015-08-03 Anti-hcmv idiotypic antibodies and uses thereof -hcmv HK1206759A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261616914P 2012-03-28 2012-03-28
PCT/US2013/032661 WO2013148373A1 (en) 2012-03-28 2013-03-15 Anti-hcmv idiotypic antibodies and uses thereof

Publications (1)

Publication Number Publication Date
HK1206759A1 true HK1206759A1 (en) 2016-01-15

Family

ID=48087712

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15107419.1A HK1206759A1 (en) 2012-03-28 2015-08-03 Anti-hcmv idiotypic antibodies and uses thereof -hcmv

Country Status (12)

Country Link
US (2) US9139659B2 (ru)
EP (1) EP2831119A1 (ru)
JP (1) JP2015518471A (ru)
KR (1) KR20140138971A (ru)
CN (1) CN104334583A (ru)
AR (1) AR090510A1 (ru)
BR (1) BR112014024023A2 (ru)
CA (1) CA2868161A1 (ru)
HK (1) HK1206759A1 (ru)
MX (1) MX2014011646A (ru)
RU (1) RU2014143251A (ru)
WO (1) WO2013148373A1 (ru)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2883534A1 (en) * 2012-10-19 2014-04-24 F. Hoffmann-La Roche Ag Inhibitors of syk
WO2018119474A2 (en) * 2016-12-23 2018-06-28 Remd Biotherapeutics, Inc. Immunotherapy using antibodies that bind programmed death 1 (pd-1)
WO2018136553A1 (en) 2017-01-18 2018-07-26 Genentech, Inc. Idiotypic antibodies against anti-pd-l1 antibodies and uses thereof
KR102344616B1 (ko) 2017-05-30 2021-12-31 더 보드 오브 리젠츠 오브 더 유니버시티 오브 오클라호마 항-더블코르틴-유사 키나제 1 항체 및 사용 방법
US12084514B2 (en) 2017-12-04 2024-09-10 The Board Of Regents Of The University Of Oklahoma Anti-DCLK1 antibodies and chimeric antigen receptors, and compositions and methods of use thereof
JP7560476B2 (ja) 2019-04-09 2024-10-02 アブクロ,インク. キラー細胞レクチン様受容体サブファミリーgメンバー1(klrg1)除去抗体
WO2021016366A1 (en) * 2019-07-22 2021-01-28 Regeneron Pharmaceuticals, Inc. Affinity chromatography-coupled native mass spectrometry for antibody analysis
CN112899235B (zh) * 2019-12-03 2024-06-21 夏尔巴生物技术(苏州)有限公司 一种细胞培养液的收获方法
WO2022251311A1 (en) * 2021-05-25 2022-12-01 Seagen Inc. Methods of quantifying anti-cd40 antibodies

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE337223B (ru) * 1967-05-23 1971-08-02 Pharmacia Ab
US3720760A (en) * 1968-09-06 1973-03-13 Pharmacia Ab Method for determining the presence of reagin-immunoglobulins(reagin-ig)directed against certain allergens,in aqueous samples
US3645090A (en) * 1969-06-19 1972-02-29 Citizen Watch Co Ltd Day-date quick-adjuster for calender timepiece
US3691016A (en) * 1970-04-17 1972-09-12 Monsanto Co Process for the preparation of insoluble enzymes
US3940475A (en) * 1970-06-11 1976-02-24 Biological Developments, Inc. Radioimmune method of assaying quantitatively for a hapten
CA1023287A (en) * 1972-12-08 1977-12-27 Boehringer Mannheim G.M.B.H. Process for the preparation of carrier-bound proteins
US4195128A (en) * 1976-05-03 1980-03-25 Bayer Aktiengesellschaft Polymeric carrier bound ligands
US4330440A (en) 1977-02-08 1982-05-18 Development Finance Corporation Of New Zealand Activated matrix and method of activation
CA1093991A (en) 1977-02-17 1981-01-20 Hideo Hirohara Enzyme immobilization with pullulan gel
US4229537A (en) 1978-02-09 1980-10-21 New York University Preparation of trichloro-s-triazine activated supports for coupling ligands
US4376110A (en) 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
US4536479A (en) * 1983-03-22 1985-08-20 E. I. Du Pont De Nemours And Company Use of anti-idiotype antibodies in immunoassays
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4737456A (en) 1985-05-09 1988-04-12 Syntex (U.S.A.) Inc. Reducing interference in ligand-receptor binding assays
US5959177A (en) 1989-10-27 1999-09-28 The Scripps Research Institute Transgenic plants expressing assembled secretory antibodies
DE69129154T2 (de) 1990-12-03 1998-08-20 Genentech, Inc., South San Francisco, Calif. Verfahren zur anreicherung von proteinvarianten mit geänderten bindungseigenschaften
JP3951062B2 (ja) 1991-09-19 2007-08-01 ジェネンテック・インコーポレーテッド 少なくとも遊離のチオールとして存在するシステインを有する抗体フラグメントの大腸菌での発現、2官能性F(ab’)2抗体の産生のための使用
US6020208A (en) 1994-05-27 2000-02-01 Baylor College Of Medicine Systems for surface-enhanced affinity capture for desorption and detection of analytes
US5789199A (en) 1994-11-03 1998-08-04 Genentech, Inc. Process for bacterial production of polypeptides
US5840523A (en) 1995-03-01 1998-11-24 Genetech, Inc. Methods and compositions for secretion of heterologous polypeptides
NZ516848A (en) 1997-06-20 2004-03-26 Ciphergen Biosystems Inc Retentate chromatography apparatus with applications in biology and medicine
US6040498A (en) 1998-08-11 2000-03-21 North Caroline State University Genetically engineered duckweed
US7125978B1 (en) 1999-10-04 2006-10-24 Medicago Inc. Promoter for regulating expression of foreign genes
ES2248127T3 (es) 1999-10-04 2006-03-16 Medicago Inc. Metodo para regular la transcripcion de genes foraneos en presencia de nigtrogeno.
CA2438247A1 (en) 2001-02-20 2002-08-29 Xian Huang A microchip electrospray device and column with affinity adsorbents and use of the same
US20080268459A1 (en) * 2003-08-14 2008-10-30 Wyeth Ludwig Institute For Cancer Anti-Lewis Y Anti-Idiotypic Antibodies and Uses Thereof
EP3031469B1 (en) 2006-06-07 2023-08-23 The Trustees Of Princeton University Cytomegalovirus surface protein complex for use in vaccines and as a drug target
WO2008071806A1 (en) 2006-12-15 2008-06-19 Ribovax Biotechnologies Sa Antibodies against human cytomegalovirus (hcmv)
US7947274B2 (en) 2007-01-04 2011-05-24 Humabs, LLC. Human cytomegalovirus neutralising antibodies and use thereof
GB0700133D0 (en) 2007-01-04 2007-02-14 Humabs Llc Human cytomegalovirus neutralising antibodies and use thereof
SG10201706350PA (en) * 2008-07-16 2017-09-28 Inst For Res In Biomedicine Human cytomegalovirus neutralizing antibodies and use thereof
JP5833565B2 (ja) * 2009-12-23 2015-12-16 4−アンティボディ・アクチェンゲゼルシャフト4−Antibody Ag ヒトサイトメガロウイルスに対する結合メンバー
WO2012047732A2 (en) * 2010-09-29 2012-04-12 Genentech, Inc. Antibody compositions and methods of use
WO2013096812A1 (en) * 2011-12-23 2013-06-27 Genentech, Inc. Articles of manufacture and methods for co-administration of antibodies

Also Published As

Publication number Publication date
JP2015518471A (ja) 2015-07-02
AR090510A1 (es) 2014-11-19
WO2013148373A8 (en) 2014-09-25
US9139659B2 (en) 2015-09-22
US20130266973A1 (en) 2013-10-10
KR20140138971A (ko) 2014-12-04
WO2013148373A1 (en) 2013-10-03
EP2831119A1 (en) 2015-02-04
CA2868161A1 (en) 2013-10-03
CN104334583A (zh) 2015-02-04
BR112014024023A2 (pt) 2017-07-18
MX2014011646A (es) 2015-02-24
RU2014143251A (ru) 2016-05-20
US20160002355A1 (en) 2016-01-07

Similar Documents

Publication Publication Date Title
HK1207092A1 (en) Anti-hla-b27 antibodies and uses thereof -hla-b27
IL238559A0 (en) Antibodies against ceacam5 and their use
ZA201500457B (en) Anti-kit antibodies and uses thereof
ZA201501858B (en) Anti-mcam antibodies and associated methods of use
HRP20190358T1 (hr) Antitijela protiv asic1 i njihova primjena
EP2832856A4 (en) ANTI-LAMP5 ANTIBODIES AND USE THEREOF
HK1197187A1 (en) Anti-lrp5 antibodies and methods of use lrp5
HK1206759A1 (en) Anti-hcmv idiotypic antibodies and uses thereof -hcmv
EP2830660A4 (en) ANTI-SEMA4D ANTIBODIES AND EPITOPES
HK1209432A1 (en) Anti-jagged antibodies and methods of use
GB201208372D0 (en) Antibodies and uses thereof