HK1206423A1 - Oligomeric a in the diagnosis, prognosis, and monitoring of alzheimer's disease - Google Patents
Oligomeric a in the diagnosis, prognosis, and monitoring of alzheimer's disease Download PDFInfo
- Publication number
- HK1206423A1 HK1206423A1 HK15106868.9A HK15106868A HK1206423A1 HK 1206423 A1 HK1206423 A1 HK 1206423A1 HK 15106868 A HK15106868 A HK 15106868A HK 1206423 A1 HK1206423 A1 HK 1206423A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- disease
- alzheimer
- monitoring
- prognosis
- diagnosis
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5082—Supracellular entities, e.g. tissue, organisms
- G01N33/5088—Supracellular entities, e.g. tissue, organisms of vertebrates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4709—Amyloid plaque core protein
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
- G01N2800/2821—Alzheimer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Tropical Medicine & Parasitology (AREA)
- Toxicology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261610390P | 2012-03-13 | 2012-03-13 | |
| US61/610,390 | 2012-03-13 | ||
| PCT/US2013/031018 WO2013138512A1 (en) | 2012-03-13 | 2013-03-13 | OLIGOMERIC Aβ IN THE DIAGNOSIS, PROGNOSIS, AND MONITORING OF ALZHEIMER'S DISEASE |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1206423A1 true HK1206423A1 (en) | 2016-01-08 |
Family
ID=49161786
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK15106868.9A HK1206423A1 (en) | 2012-03-13 | 2013-03-13 | Oligomeric a in the diagnosis, prognosis, and monitoring of alzheimer's disease |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20130273574A1 (enExample) |
| EP (1) | EP2825884A4 (enExample) |
| JP (1) | JP2015511014A (enExample) |
| CN (1) | CN104662423A (enExample) |
| CA (1) | CA2867338A1 (enExample) |
| HK (1) | HK1206423A1 (enExample) |
| WO (1) | WO2013138512A1 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20140128230A (ko) * | 2013-04-26 | 2014-11-05 | 한국과학기술연구원 | 혈액 중 단백질 응집체의 용해를 통한 단백질의 비정상적인 응집 또는 미스폴딩과 관련된 질환 또는 질병을 진단하는 진단키트 |
| US20180188270A1 (en) * | 2015-06-30 | 2018-07-05 | Health Research, Inc. | Diagnostic test for alzheimer's disease based on identification of a proteolytic pathway |
| CN105542005B (zh) * | 2016-02-03 | 2018-11-09 | 大连理工大学 | 一种抗人淀粉样β肽的纳米抗体及其应用 |
| JP6883847B2 (ja) * | 2017-03-30 | 2021-06-09 | 国立大学法人滋賀医科大学 | アミロイドβ蛋白並びにタウ蛋白及び／又はリン酸化タウ蛋白の測定方法 |
| US20200400687A1 (en) * | 2017-12-19 | 2020-12-24 | Chase Therapeutics Corporation | Methods for developing pharmaceuticals for treating neurodegenerative conditions |
| EP3760640A4 (en) * | 2018-02-27 | 2021-11-17 | Shimadzu Corporation | ANTIBODIES SPECIFICALLY RECOGNIZING THE N-TERMINAL END OF APP669-X, AND METHOD OF IMMUNOLOGICAL ASSAY |
| CN109187981A (zh) * | 2018-08-01 | 2019-01-11 | 万东山 | 一种快速检测β-淀粉样蛋白的量子点免疫层析试纸条与应用 |
| KR101977410B1 (ko) * | 2018-08-22 | 2019-05-10 | 주식회사 피플바이오 | 당뇨병에 대한 신규 바이오마커 및 그의 용도 |
| CN113597429A (zh) * | 2019-03-01 | 2021-11-02 | 株式会社岛津制作所 | App669-711测定方法及测定用试剂盒 |
| CA3176743A1 (en) * | 2019-04-04 | 2020-10-08 | The Royal Institution For The Advancement Of Learning / Mcgill University | Use of a.beta.34 to assess alzheimer's disease progression |
| BR112022000322A2 (pt) * | 2019-07-10 | 2022-02-22 | Todos Medical Ltd | Um biomarcador para doença de alzheimer com o uso de amostras de sangue de indivíduos clinicamente diagnosticados com doença de alzheimer |
| WO2021030615A1 (en) * | 2019-08-13 | 2021-02-18 | Washington University | Methods to detect mtbr tau isoforms and use thereof |
| WO2021090910A1 (ja) * | 2019-11-08 | 2021-05-14 | セントラル硝子株式会社 | タンパク質凝集塊を検出する分子構造変質剤、その検出方法、医療器具用洗浄剤、土壌洗浄剤及び土壌の洗浄方法 |
| CN111393524B (zh) * | 2020-02-20 | 2022-04-08 | 北京化工大学 | 基于金属标记的阿尔兹海默症脑组织Aβ蛋白的原位检测方法 |
| WO2022150754A2 (en) * | 2021-01-11 | 2022-07-14 | University Of Florida Research Foundation, Incorporated | Anticancer compounds and uses thereof |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10303974A1 (de) * | 2003-01-31 | 2004-08-05 | Abbott Gmbh & Co. Kg | Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung |
| KR20080021585A (ko) * | 2005-03-05 | 2008-03-07 | 애보트 게엠베하 운트 콤파니 카게 | 스크리닝 방법, 비확산성 ａ-베타 올리고머의 정제 방법,당해 비확산성 ａ-베타 올리고머에 대한 선택적 항체 및당해 항체의 제조 방법 |
| AU2008204335B2 (en) * | 2007-01-11 | 2013-06-13 | Michael Bacher | Diagnosis and treatment of Alzheimer's and other neurodementing diseases |
| US8022268B2 (en) * | 2007-06-11 | 2011-09-20 | The University Of Zurich | Transgenic animal model for alzheimer's disease |
| CA2714413C (en) * | 2008-02-08 | 2017-01-24 | Immunas Pharma, Inc. | Antibody capable of binding specifically to ab-oligomer, and use thereof |
| CN101531717B (zh) * | 2009-04-22 | 2012-07-18 | 北京交通大学 | 抗阿尔茨海默病单克隆抗体及其应用 |
| WO2011064225A1 (en) * | 2009-11-24 | 2011-06-03 | Probiodrug Ag | Novel diagnostic method for the diagnosis of alzheimer's disease or mild cgnitive impairment |
| JP5747444B2 (ja) * | 2010-04-27 | 2015-07-15 | パナソニックヘルスケア株式会社 | βアミロイドに関連する病的状態の診断補助方法 |
-
2013
- 2013-03-13 US US13/801,844 patent/US20130273574A1/en not_active Abandoned
- 2013-03-13 CN CN201380021783.5A patent/CN104662423A/zh active Pending
- 2013-03-13 JP JP2015500571A patent/JP2015511014A/ja active Pending
- 2013-03-13 HK HK15106868.9A patent/HK1206423A1/xx unknown
- 2013-03-13 WO PCT/US2013/031018 patent/WO2013138512A1/en not_active Ceased
- 2013-03-13 EP EP13760620.8A patent/EP2825884A4/en not_active Withdrawn
- 2013-03-13 CA CA2867338A patent/CA2867338A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2015511014A (ja) | 2015-04-13 |
| EP2825884A4 (en) | 2015-11-11 |
| US20130273574A1 (en) | 2013-10-17 |
| CN104662423A (zh) | 2015-05-27 |
| CA2867338A1 (en) | 2013-09-19 |
| WO2013138512A1 (en) | 2013-09-19 |
| EP2825884A1 (en) | 2015-01-21 |
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