HK1200095A1 - Formulations of histone deacetylase inhibitor in combination with bendamustine and uses thereof - Google Patents
Formulations of histone deacetylase inhibitor in combination with bendamustine and uses thereofInfo
- Publication number
- HK1200095A1 HK1200095A1 HK15100523.9A HK15100523A HK1200095A1 HK 1200095 A1 HK1200095 A1 HK 1200095A1 HK 15100523 A HK15100523 A HK 15100523A HK 1200095 A1 HK1200095 A1 HK 1200095A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- bendamustine
- formulations
- combination
- histone deacetylase
- deacetylase inhibitor
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US2011/051470 WO2013039488A1 (en) | 2011-09-13 | 2011-09-13 | Formulations of histone deacetylase inhibitor in combination with bendamustine and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1200095A1 true HK1200095A1 (en) | 2015-07-31 |
Family
ID=47883567
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK15100523.9A HK1200095A1 (en) | 2011-09-13 | 2015-01-16 | Formulations of histone deacetylase inhibitor in combination with bendamustine and uses thereof |
Country Status (15)
Country | Link |
---|---|
US (1) | US9492423B2 (es) |
EP (1) | EP2755648B1 (es) |
JP (1) | JP6330118B2 (es) |
KR (1) | KR101892788B1 (es) |
CN (1) | CN103917231B (es) |
AU (1) | AU2011376953B2 (es) |
CA (1) | CA2845806C (es) |
ES (1) | ES2627820T3 (es) |
HK (1) | HK1200095A1 (es) |
MX (1) | MX365393B (es) |
NZ (1) | NZ621221A (es) |
RU (1) | RU2609833C2 (es) |
SG (1) | SG2014014419A (es) |
UA (1) | UA110853C2 (es) |
WO (1) | WO2013039488A1 (es) |
Families Citing this family (22)
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DK2099442T3 (en) | 2006-12-26 | 2015-02-16 | Pharmacyclics Inc | Method of using histone deacetylase inhibitors and monitoring biomarkers in combination therapy |
US9492423B2 (en) | 2011-09-13 | 2016-11-15 | Pharmacyclics Llc | Formulations of histone deacetylase inhibitor in combination with bendamustine and uses thereof |
AR092790A1 (es) | 2012-02-01 | 2015-05-06 | Euro Celtique Sa | Derivados bencimidazolicos del acido hidroxamico |
GB201409488D0 (en) | 2014-05-28 | 2014-07-09 | Euro Celtique Sa | Pharmaceutical composition |
GB201409485D0 (en) | 2014-05-28 | 2014-07-09 | Euro Celtique Sa | Pharmaceutical composition |
GB201409471D0 (en) | 2014-05-28 | 2014-07-09 | Euro Celtique Sa | Pharmaceutical composition |
JP2017537164A (ja) * | 2014-12-05 | 2017-12-14 | ユニヴァーシティ・オブ・モデナ・アンド・レッジョ・エミリア | リンパ腫の治療に使用されるヒストン脱アセチル化酵素阻害剤とベンダムスチンとの組み合わせ |
EP3310168A4 (en) * | 2015-06-19 | 2019-03-06 | Trustees of Boston University | METHODS AND COMPOSITIONS FOR TREATING CONDITIONS INDUCED BY HERPETIC VIRUS |
US20200179381A1 (en) * | 2016-04-08 | 2020-06-11 | Cereno Scientific Ab | Compounds and compositions for the treatment or prevention of pathological conditions associated with excess fibrin deposition and/or thrombus formation |
CN109069439A (zh) * | 2016-04-21 | 2018-12-21 | 瓦尔库里亚公司 | 用于预处理癌症的组合物和方法 |
AU2016426574B2 (en) | 2016-10-11 | 2023-07-13 | Euro-Celtique S.A. | Hodgkin lymphoma therapy |
SG10201609137PA (en) * | 2016-11-01 | 2018-06-28 | Xylonix Ip Holdings Pte Ltd | Gamma-polyglutamic acid and zinc compositions |
SG10201609131YA (en) | 2016-11-01 | 2018-06-28 | Xylonix Ip Holdings Pte Ltd | Zinc-pga compositions and methods for treating cancer |
GB201706544D0 (en) | 2017-04-25 | 2017-06-07 | Plasticell Ltd | Method |
GB201709406D0 (en) | 2017-06-13 | 2017-07-26 | Euro-Cletique S A | Compounds for treating TNBC |
GB201709403D0 (en) | 2017-06-13 | 2017-07-26 | Euro Celtique Sa | Compounds for treating sarcoma |
GB201709405D0 (en) | 2017-06-13 | 2017-07-26 | Euro Celtique Sa | Compounds for treating ovarian cancer |
GB201709402D0 (en) | 2017-06-13 | 2017-07-26 | Euro Celtique Sa | Compounds for treating t-pll |
KR102338992B1 (ko) | 2018-01-05 | 2021-12-14 | 지엔티 바이오테크 & 메디컬즈 코포레이션 | 종양 미세환경 및 면역요법의 조절을 위한 약제학적 조합물 및 방법 |
EP3976198A4 (en) | 2019-05-31 | 2023-07-19 | Viracta Subsidiary, Inc. | METHODS OF TREATMENT OF VIRAL ASSOCIATED CANCER WITH HISTONE DEACETYLASE INHIBITORS |
WO2022159852A1 (en) * | 2021-01-25 | 2022-07-28 | Icahn School Of Medicine At Mount Sinai | Methods and compositions for treating adenoid cystic carcinoma |
WO2024086688A1 (en) * | 2022-10-21 | 2024-04-25 | Viracta Subsidiary, Inc. | Dosing methods for hdac inhibitor compounds |
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UY34295A (es) | 2011-09-08 | 2013-04-30 | Servier Lab | Nuevo esquema de administración de la n-hidroxi -4- {2-[3- (n,ndimetilaminometil)benzofuran -2- ilcarbonilamino]etoxi}benzamida |
US9492423B2 (en) | 2011-09-13 | 2016-11-15 | Pharmacyclics Llc | Formulations of histone deacetylase inhibitor in combination with bendamustine and uses thereof |
EP3027192A4 (en) | 2013-08-02 | 2017-03-22 | Pharmacyclics, LLC | Methods for the treatment of solid tumors |
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2011
- 2011-09-13 US US14/344,314 patent/US9492423B2/en active Active
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- 2011-09-13 RU RU2014111069A patent/RU2609833C2/ru not_active IP Right Cessation
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- 2011-09-13 EP EP11872389.9A patent/EP2755648B1/en active Active
- 2011-09-13 AU AU2011376953A patent/AU2011376953B2/en active Active
- 2011-09-13 CN CN201180074826.7A patent/CN103917231B/zh active Active
- 2011-09-13 ES ES11872389.9T patent/ES2627820T3/es active Active
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AU2011376953A1 (en) | 2014-03-06 |
CA2845806C (en) | 2019-06-11 |
RU2014111069A (ru) | 2015-10-20 |
JP6330118B2 (ja) | 2018-05-30 |
CN103917231B (zh) | 2016-09-28 |
ES2627820T3 (es) | 2017-07-31 |
MX2014002942A (es) | 2014-09-15 |
WO2013039488A1 (en) | 2013-03-21 |
AU2011376953B2 (en) | 2017-08-24 |
US20140341989A1 (en) | 2014-11-20 |
CA2845806A1 (en) | 2013-03-21 |
EP2755648A4 (en) | 2015-03-11 |
KR20140073503A (ko) | 2014-06-16 |
NZ621221A (en) | 2016-07-29 |
MX365393B (es) | 2019-05-31 |
JP2014526503A (ja) | 2014-10-06 |
RU2609833C2 (ru) | 2017-02-06 |
EP2755648A1 (en) | 2014-07-23 |
US9492423B2 (en) | 2016-11-15 |
SG2014014419A (en) | 2014-07-30 |
EP2755648B1 (en) | 2017-03-08 |
KR101892788B1 (ko) | 2018-08-28 |
UA110853C2 (uk) | 2016-02-25 |
CN103917231A (zh) | 2014-07-09 |
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Free format text: CORRECTED DATA OF SECTION 27 TO JOURNAL OF 20180302: (54) FORMULATIONS OF HISTONE DEACETYLASE INHIBITOR IN COMBINATION WITH BENDAMUSTINE AND USES THEREOF |