HK1197724A1 - 1h-pyrazolo[3,4-b]pyridines and therapeutic uses thereof 1 -[34-b] - Google Patents

1h-pyrazolo[3,4-b]pyridines and therapeutic uses thereof 1 -[34-b]

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Publication number
HK1197724A1
HK1197724A1 HK14110200.9A HK14110200A HK1197724A1 HK 1197724 A1 HK1197724 A1 HK 1197724A1 HK 14110200 A HK14110200 A HK 14110200A HK 1197724 A1 HK1197724 A1 HK 1197724A1
Authority
HK
Hong Kong
Prior art keywords
pyrazolo
pyridines
therapeutic uses
therapeutic
Prior art date
Application number
HK14110200.9A
Other languages
English (en)
Chinese (zh)
Inventor
John Hood
Sunil Kumar Kc
David Mark Wallace
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of HK1197724A1 publication Critical patent/HK1197724A1/xx

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    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • A—HUMAN NECESSITIES
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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  • Hematology (AREA)
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  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Oncology (AREA)
  • Dispersion Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
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HK14110200.9A 2012-05-04 2014-10-13 1h-pyrazolo[3,4-b]pyridines and therapeutic uses thereof 1 -[34-b] HK1197724A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261642915P 2012-05-04 2012-05-04
PCT/US2013/039484 WO2013166396A2 (en) 2012-05-04 2013-05-03 1h-pyrazolo[3,4-b]pyridines and therapeutic uses thereof

Publications (1)

Publication Number Publication Date
HK1197724A1 true HK1197724A1 (en) 2015-03-13

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ID=49513001

Family Applications (1)

Application Number Title Priority Date Filing Date
HK14110200.9A HK1197724A1 (en) 2012-05-04 2014-10-13 1h-pyrazolo[3,4-b]pyridines and therapeutic uses thereof 1 -[34-b]

Country Status (33)

Country Link
US (8) US8883822B2 (sl)
EP (2) EP3593800A1 (sl)
JP (3) JP6209593B2 (sl)
KR (1) KR102223301B1 (sl)
CN (2) CN104271133B (sl)
AU (2) AU2013256141B2 (sl)
BR (1) BR112014024284B1 (sl)
CA (1) CA2854229C (sl)
CL (1) CL2014002983A1 (sl)
CO (1) CO7170178A2 (sl)
CY (1) CY1122703T1 (sl)
DK (1) DK2770994T3 (sl)
ES (1) ES2752192T3 (sl)
HK (1) HK1197724A1 (sl)
HR (1) HRP20191799T1 (sl)
HU (1) HUE046216T2 (sl)
IL (2) IL235018B (sl)
LT (1) LT2770994T (sl)
MA (1) MA37577B1 (sl)
ME (1) ME03573B (sl)
MX (1) MX362466B (sl)
MY (1) MY173049A (sl)
NZ (3) NZ629282A (sl)
PE (1) PE20142365A1 (sl)
PH (3) PH12014502369B1 (sl)
PL (1) PL2770994T3 (sl)
PT (1) PT2770994T (sl)
RS (1) RS59668B1 (sl)
RU (1) RU2689141C2 (sl)
SG (2) SG11201407148XA (sl)
SI (1) SI2770994T1 (sl)
WO (1) WO2013166396A2 (sl)
ZA (2) ZA201406274B (sl)

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NO3001903T3 (sl) 2009-12-21 2018-03-24
WO2012177647A2 (en) 2011-06-20 2012-12-27 Kerry Lane Mycotoxin diagnostics and methods thereof
PT2755483T (pt) 2011-09-14 2019-02-18 Samumed Llc Indazol-3-carboxamidas e sua utilização como inibidores da via de sinalização de wnt/β-catenina
PH12017500997A1 (en) 2012-04-04 2018-02-19 Samumed Llc Indazole inhibitors of the wnt signal pathway and therapeutic uses thereof
EP3593800A1 (en) 2012-05-04 2020-01-15 Samumed, LLC 1h-pyrazolo[3,4-b]pyridines and therapeutic uses thereof
CA2897400A1 (en) 2013-01-08 2014-07-17 Samumed, Llc 3-(benzoimidazol-2-yl)-indazole inhibitors of the wnt signaling pathway and therapeutic uses thereof
HRP20230086T1 (hr) * 2013-12-11 2023-03-31 Celgene Quanticel Research, Inc. Inhibitori lizin specifične demetilaze-1
JP6434989B2 (ja) * 2014-03-27 2018-12-05 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ ピリジルピペリジン
WO2016040181A1 (en) 2014-09-08 2016-03-17 Samumed, Llc 3-(1h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof
WO2016040180A1 (en) 2014-09-08 2016-03-17 Samumed, Llc 3-(1h-benzo[d]imidazol-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof
WO2016040182A1 (en) 2014-09-08 2016-03-17 Samumed, Llc 2-(1h-indazol-3-yl)-1h-imidazo[4,5-c]pyridine and therapeutic uses thereof
WO2016040190A1 (en) 2014-09-08 2016-03-17 Samumed, Llc 3-(3h-imidazo[4,5-b]pyridin-2-yl)-1h-pyrazolo[3,4-b]pyridine and therapeutic uses thereof
WO2016040185A1 (en) 2014-09-08 2016-03-17 Samumed, Llc 2-(1h-indazol-3-yl)-3h-imidazo[4,5-b]pyridine and therapeutic uses thereof
WO2016040184A1 (en) 2014-09-08 2016-03-17 Samumed, Llc 3-(3h-imidazo[4,5-b]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof
WO2016040188A1 (en) 2014-09-08 2016-03-17 Samumed, Llc 3-(3h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof
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