HK1197551A1 - 抗炎症的 -羰基噻唑和 -羰基惡唑 - Google Patents
抗炎症的 -羰基噻唑和 -羰基惡唑Info
- Publication number
- HK1197551A1 HK1197551A1 HK14111229.4A HK14111229A HK1197551A1 HK 1197551 A1 HK1197551 A1 HK 1197551A1 HK 14111229 A HK14111229 A HK 14111229A HK 1197551 A1 HK1197551 A1 HK 1197551A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- oxooxazoles
- oxothiazoles
- anti inflammatory
- inflammatory
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/24—Radicals substituted by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/421—1,3-Oxazoles, e.g. pemoline, trimethadione
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/423—Oxazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/28—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/30—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US24833809P | 2009-10-02 | 2009-10-02 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1197551A1 true HK1197551A1 (zh) | 2015-01-23 |
Family
ID=43221889
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK14111229.4A HK1197551A1 (zh) | 2009-10-02 | 2014-11-05 | 抗炎症的 -羰基噻唑和 -羰基惡唑 |
HK15110908.3A HK1210157A1 (zh) | 2009-10-02 | 2015-11-05 | 抗炎症的 -羰基噻唑和 -羰基惡唑 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK15110908.3A HK1210157A1 (zh) | 2009-10-02 | 2015-11-05 | 抗炎症的 -羰基噻唑和 -羰基惡唑 |
Country Status (12)
Country | Link |
---|---|
US (2) | US9597318B2 (zh) |
EP (2) | EP3431084A1 (zh) |
JP (1) | JP6012468B2 (zh) |
KR (4) | KR101907535B1 (zh) |
CN (3) | CN104892542B (zh) |
AU (1) | AU2010302584B2 (zh) |
CA (1) | CA2782797C (zh) |
DK (1) | DK2482815T3 (zh) |
HK (2) | HK1197551A1 (zh) |
IN (1) | IN2012DN02982A (zh) |
NO (1) | NO2482815T3 (zh) |
WO (1) | WO2011039365A1 (zh) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101907535B1 (ko) | 2009-10-02 | 2018-10-15 | 아벡신 에이에스 | 소염제 2-옥소티아졸 및 2-옥소옥사졸 |
GB201205394D0 (en) | 2012-03-27 | 2012-05-09 | Adlens Ltd | Improvements in or relating to deformable non-round membrane assemblies |
GB201221329D0 (en) * | 2012-11-27 | 2013-01-09 | Avexxin As | Dermatitis treatment |
WO2014118195A1 (en) * | 2013-01-29 | 2014-08-07 | Avexxin As | Antiinflammatory and antitumor 2-oxothiazoles and 2-oxothiophenes compounds |
GB201307331D0 (en) * | 2013-04-23 | 2013-05-29 | Norwegian Univ Sci & Tech Ntnu | Compound |
GB201409363D0 (en) | 2014-05-27 | 2014-07-09 | Avexxin As | Skin cancer treatment |
GB201413695D0 (en) | 2014-08-01 | 2014-09-17 | Avexxin As | Compound |
GB201604316D0 (en) | 2016-03-14 | 2016-04-27 | Avexxin As | Combination therapy |
GB201604318D0 (en) | 2016-03-14 | 2016-04-27 | Avexxin As | Combination therapy |
GB2550363A (en) * | 2016-05-16 | 2017-11-22 | Avexxin As | Compound |
KR20190055153A (ko) | 2016-09-21 | 2019-05-22 | 아벡신 에이에스 | 약학 조성물 |
EP3534955A1 (en) * | 2016-11-04 | 2019-09-11 | Avexxin AS | Combination therapy comprising a thiazole and a corticosteroid to treat skin conditions |
AU2017353450B2 (en) * | 2016-11-04 | 2020-09-10 | Avexxin As | Combination therapy comprising a thiazole and a secosteroid to treat skin conditions |
JP7169584B2 (ja) * | 2018-01-30 | 2022-11-11 | 公立大学法人横浜市立大学 | オーキシン生合成阻害活性を有する新規化合物、その製造方法及びその用途 |
GB201806663D0 (en) | 2018-04-24 | 2018-06-06 | Avexxin As | 2-Oxothiazole compositions for treatment of fibrotic disease |
EP3677259A1 (en) * | 2019-01-07 | 2020-07-08 | Mosaiques Diagnostics And Therapeutics AG | Use of arachidonyl trifluoromethyl ketone |
GB202117609D0 (en) | 2021-12-06 | 2022-01-19 | Coegin Pharma Ab | 2-Oxothiazole compositions for treatment of T-cell acute lymphoblastic leukaemia |
CN115028597B (zh) * | 2022-04-29 | 2024-03-26 | 闽都创新实验室 | 一种tempo连续脱氢环化制备苯并恶唑类衍生物的方法和应用 |
Family Cites Families (63)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3894152A (en) * | 1969-09-15 | 1975-07-08 | Innothera Lab Sa | Use of (thienyl-3)(3-N-morpholine-propy)ketone |
FR2062868B1 (zh) * | 1969-09-15 | 1973-08-10 | Innothera Lab Sa | |
DE2063901A1 (en) | 1970-12-28 | 1972-07-20 | Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler, 6000 Frankfurt | Phenylalkylaminoalkylthiazoles - as antiphlogistics |
PH22520A (en) | 1984-11-12 | 1988-10-17 | Yamanouchi Pharma Co Ltd | Heterocyclic compounds having 4-lover alkyl-3-hydroxy-2-lower alkyl phenoxy-lower alkylene-y-group, and process of producing them |
US5177215A (en) | 1984-11-12 | 1993-01-05 | Yamanouchi Pharmaceutical Co., Ltd. | Heterocyclic compounds and pharmaceutical use thereof |
JPS62142168A (ja) | 1985-10-16 | 1987-06-25 | Mitsubishi Chem Ind Ltd | チアゾ−ル誘導体及びそれを有効成分とするロイコトリエンきつ抗剤 |
ZA894913B (en) | 1988-07-12 | 1990-03-28 | Ici Pharma | Heterocyclic compounds |
US5272986A (en) | 1991-05-13 | 1993-12-28 | British Gas Plc | Towing swivel for pipe inspection or other vehicle |
TW263504B (zh) | 1991-10-03 | 1995-11-21 | Pfizer | |
GB9211706D0 (en) | 1992-06-03 | 1992-07-15 | Celltech Ltd | Peptidyl derivatives |
US5273986A (en) | 1992-07-02 | 1993-12-28 | Hoffmann-La Roche Inc. | Cycloalkylthiazoles |
US5268395A (en) | 1992-10-13 | 1993-12-07 | Martin Marietta Energy Systems, Inc. | Microcellular carbon foam and method |
JP3345476B2 (ja) * | 1993-05-18 | 2002-11-18 | 株式会社東芝 | 有機非線形光学材料 |
US5569655A (en) * | 1993-09-14 | 1996-10-29 | Sterling Winthrop Inc. | Substituted heterocyclylisoquinolinium salts and compositions and method of use thereof |
CA2195847A1 (en) | 1994-07-27 | 1996-02-08 | John J. Talley | Substituted thiazoles for the treatment of inflammation |
US5693804A (en) * | 1994-11-17 | 1997-12-02 | Molecular Geriatrics Corporation | Substituted 1-aryl-3-piperazin-1'-yl propanones |
US6214994B1 (en) * | 1997-04-21 | 2001-04-10 | Molecular Geriatrics Corporation | Certain substituted 1-aryl-3-piperazin-1′-yl propanones |
US5658909A (en) * | 1994-11-17 | 1997-08-19 | Molecular Geriatrics Corporation | Certain substituted 1-aryl-3-piperazin-1'-yl propanones to treat Alzheimer's Disease |
CN1063443C (zh) | 1995-03-28 | 2001-03-21 | 日本脏器制药株式会社 | 新的苯并噻唑衍生物 |
WO1996036617A1 (en) * | 1995-05-19 | 1996-11-21 | G.D. Searle & Co. | Substituted oxazoles for the treatment of inflammation |
CA2224121A1 (en) * | 1995-06-06 | 1996-12-12 | Donna Kaye Wilson | Stereoselective method for synthesizing dolaphenine |
DE19638408A1 (de) * | 1996-09-19 | 1998-03-26 | Merckle Gmbh | 1-Substituierte 3-Acyl-4,5-dimethylpyrrol-2-carbonsäuren und 3-Acylindol-2-carbonsäuren sowie ihre Derivate als Hemmstoffe der cytosolischen Phospholipase A¶2¶ |
US6414145B1 (en) * | 1997-01-29 | 2002-07-02 | Zeneca Limited | Imidazolyl compounds as inhibitors of farnesyl-protein tranferase |
EP0867437B1 (en) | 1997-03-14 | 2002-11-13 | Koninklijke Philips Electronics N.V. | "Method of preparing a thiophene-containing or furan -containing conjugated compound and precursor compound used therein". |
CA2304503A1 (en) * | 1997-09-23 | 1999-04-01 | Graham Johnson | Selective cpla2 inhibitors |
JPH11255700A (ja) | 1998-03-12 | 1999-09-21 | Taiho Ind Co Ltd | アセチルアセトン系金属錯体及びその合成法、並びにそれを用いた有機多層型エレクトロルミネッセンス素子 |
US6310049B1 (en) | 1998-08-11 | 2001-10-30 | Nihon Bayer Agrochem K.K. | Nematicidal pyrazoles |
SE9804212D0 (sv) * | 1998-12-04 | 1998-12-04 | Astra Pharma Prod | Compounds |
AU5880600A (en) | 1999-06-25 | 2001-01-31 | Merck & Co., Inc. | 1-(aromatic- or heteroaromatic-substituted)-3-(heteroaromatic substituted)-1,3-propanediones and uses thereof |
JP2001240593A (ja) * | 1999-10-12 | 2001-09-04 | Japan Tobacco Inc | 高トリグリセリド血症治療薬及び抗肥満薬 |
US6462054B1 (en) * | 2000-03-27 | 2002-10-08 | The Scripps Research Institute | Inhibitors of fatty acid amide hydrolase |
WO2001087878A1 (fr) | 2000-05-18 | 2001-11-22 | Daiichi Pharmaceutical Co., Ltd. | Nouveaux dérivés de benzothiophène |
US20020052373A1 (en) | 2000-10-26 | 2002-05-02 | Zorn Stevin H. | Combination treatment for dementia or cognitive deficits associated with alzheimer's disease and parkinson's disease |
US6734207B2 (en) * | 2001-04-20 | 2004-05-11 | Parker Hughes Institute | Cytotoxic compounds |
US7056917B2 (en) | 2001-04-26 | 2006-06-06 | Daiichi Pharmaceutical Co., Ltd. | Drug efflux pump inhibitor |
US6795725B2 (en) | 2001-12-18 | 2004-09-21 | 3Pcm Company | Method and apparatus for endoscopic measurement of myoelectrical activity from the stomach and other hollow intra-abdominal organs |
GB0202002D0 (en) * | 2002-01-29 | 2002-03-13 | Leiv Eiriksson Nyotek A S | Use |
KR20050025189A (ko) | 2002-07-27 | 2005-03-11 | 아스트라제네카 아베 | 화학 화합물 |
SE0202463D0 (sv) * | 2002-08-14 | 2002-08-14 | Astrazeneca Ab | Novel compounds |
US6930391B2 (en) | 2002-08-27 | 2005-08-16 | Intel Corporation | Method for alloy-electroplating group IB metals with refractory metals for interconnections |
AU2003275493A1 (en) | 2002-10-08 | 2004-05-04 | The Scripps Research Institute | Inhibitors of fatty acid amide hydrolase |
GB2394894B (en) | 2002-11-04 | 2005-08-31 | G W Pharma Ltd | New use for pharmaceutical composition |
US20060058315A1 (en) * | 2002-11-07 | 2006-03-16 | Astrazeneca Ab | 2-Oxo-ethanesulfonamide derivates |
WO2005028465A1 (ja) | 2003-09-18 | 2005-03-31 | Tokuyama Corporation | クロメン化合物 |
AR045651A1 (es) | 2003-09-19 | 2005-11-02 | Solvay Pharm Bv | Derivados de tiazol como moduladores del receptor de cannabinoide |
JP4226438B2 (ja) | 2003-10-23 | 2009-02-18 | エヌ・ティ・ティ・コムウェア株式会社 | パック装置およびセンステーブル装置、ならびに移動軌跡算出方法、移動軌跡算出プログラム、その記録媒体 |
US20050137243A1 (en) | 2003-12-23 | 2005-06-23 | Souers Andrew J. | Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor |
JP2005343889A (ja) * | 2004-05-06 | 2005-12-15 | Taisho Pharmaceut Co Ltd | イミダゾピリジン誘導体 |
KR101242310B1 (ko) | 2004-05-17 | 2013-03-12 | 오츠카 세이야쿠 가부시키가이샤 | 티아졸 화합물 및 그의 용도 |
US7178364B2 (en) | 2004-07-22 | 2007-02-20 | Shapiro Kristen M | Personal adornment |
WO2006016218A1 (en) * | 2004-08-03 | 2006-02-16 | Pfizer Japan Inc. | Aryl or heteroaryl carbonyl derivatives derivatives useful as vanilloid receptor 1 (vr1) antagonists |
KR20060058632A (ko) * | 2004-11-25 | 2006-05-30 | 주식회사 엘지생명과학 | PPAR gamma와 PPAR alpha의 활성을항진시키는 신규 화합물, 그것의 제조방법, 및 그것을함유한 약제 조성물 |
US20090111778A1 (en) * | 2005-11-18 | 2009-04-30 | Richard Apodaca | 2-Keto-Oxazoles as Modulators of Fatty Acid Amide Hydrolase |
MY162590A (en) | 2005-12-13 | 2017-06-30 | Incyte Holdings Corp | Heteroaryl substituted pyrrolo[2,3-b] pyridines and pyrrolo[2,3-b] pyrimidines as janus kinase inhibitors |
CA2642737A1 (en) * | 2006-02-17 | 2007-08-30 | The Scripps Research Institute | Oxazole ketones as modulators of fatty acid amide hydrolase |
WO2008013963A2 (en) * | 2006-07-28 | 2008-01-31 | University Of Connecticut | Fatty acid amide hydrolase inhibitors |
EP2116530B1 (en) | 2007-02-26 | 2012-11-14 | Santen Pharmaceutical Co., Ltd | Novel pyrrole derivative having ureide group and aminocarbonyl group as substituents |
AU2008223916A1 (en) * | 2007-03-05 | 2008-09-12 | F. Hoffmann-La Roche Ag | Aminoamides as orexin antagonists |
WO2008150492A1 (en) * | 2007-05-31 | 2008-12-11 | The Scripps Research Institute | Tricyclic inhibitors of fatty acid amide hydrolase |
KR101907535B1 (ko) | 2009-10-02 | 2018-10-15 | 아벡신 에이에스 | 소염제 2-옥소티아졸 및 2-옥소옥사졸 |
WO2012070420A1 (ja) | 2010-11-22 | 2012-05-31 | 日立化成工業株式会社 | 希土類金属錯体 |
WO2014118195A1 (en) * | 2013-01-29 | 2014-08-07 | Avexxin As | Antiinflammatory and antitumor 2-oxothiazoles and 2-oxothiophenes compounds |
GB201413695D0 (en) * | 2014-08-01 | 2014-09-17 | Avexxin As | Compound |
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2010
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- 2010-10-01 IN IN2982DEN2012 patent/IN2012DN02982A/en unknown
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- 2010-10-01 NO NO10759934A patent/NO2482815T3/no unknown
- 2010-10-01 CN CN201080056033.8A patent/CN102647984B/zh active Active
- 2010-10-01 KR KR1020187028820A patent/KR101997163B1/ko active IP Right Grant
- 2010-10-01 KR KR1020197018997A patent/KR20190082985A/ko not_active Application Discontinuation
- 2010-10-01 DK DK10759934.2T patent/DK2482815T3/en active
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- 2010-10-01 JP JP2012531448A patent/JP6012468B2/ja active Active
- 2010-10-01 EP EP18170271.3A patent/EP3431084A1/en not_active Withdrawn
- 2010-10-01 WO PCT/EP2010/064687 patent/WO2011039365A1/en active Application Filing
- 2010-10-01 KR KR1020127011173A patent/KR20120089701A/ko active Application Filing
- 2010-10-01 AU AU2010302584A patent/AU2010302584B2/en active Active
- 2010-10-01 EP EP10759934.2A patent/EP2482815B1/en active Active
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Also Published As
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CN104892542A (zh) | 2015-09-09 |
US20110136879A1 (en) | 2011-06-09 |
CA2782797C (en) | 2018-08-07 |
EP2482815B1 (en) | 2018-05-02 |
EP3431084A1 (en) | 2019-01-23 |
AU2010302584B2 (en) | 2015-09-10 |
US10370344B2 (en) | 2019-08-06 |
KR20170038941A (ko) | 2017-04-07 |
KR101997163B1 (ko) | 2019-07-08 |
JP6012468B2 (ja) | 2016-10-25 |
KR101907535B1 (ko) | 2018-10-15 |
NO2482815T3 (zh) | 2018-09-29 |
IN2012DN02982A (zh) | 2015-07-31 |
EP2482815A1 (en) | 2012-08-08 |
US9597318B2 (en) | 2017-03-21 |
DK2482815T3 (en) | 2018-06-06 |
KR20190082985A (ko) | 2019-07-10 |
CN102647984B (zh) | 2015-03-25 |
KR20180114228A (ko) | 2018-10-17 |
CA2782797A1 (en) | 2011-04-07 |
US20170166539A1 (en) | 2017-06-15 |
WO2011039365A1 (en) | 2011-04-07 |
CN104892542B (zh) | 2018-01-26 |
CN102647984A (zh) | 2012-08-22 |
HK1210157A1 (zh) | 2016-04-15 |
JP2013506639A (ja) | 2013-02-28 |
AU2010302584A1 (en) | 2012-05-24 |
KR20120089701A (ko) | 2012-08-13 |
CN103772312A (zh) | 2014-05-07 |
CN103772312B (zh) | 2016-08-17 |
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