HK1196358A1 - 取代的吡啶- -酮和噠嗪- -酮 - Google Patents

取代的吡啶- -酮和噠嗪- -酮

Info

Publication number
HK1196358A1
HK1196358A1 HK14109767.6A HK14109767A HK1196358A1 HK 1196358 A1 HK1196358 A1 HK 1196358A1 HK 14109767 A HK14109767 A HK 14109767A HK 1196358 A1 HK1196358 A1 HK 1196358A1
Authority
HK
Hong Kong
Prior art keywords
ones
pyridazin
substituted pyridin
pyridin
substituted
Prior art date
Application number
HK14109767.6A
Other languages
English (en)
Inventor
諾蘭．詹姆斯．德沃丹尼
拉馬．
．孔杜
布拉德利．
．洛伊
婁岩
喬爾．麥金托什
蒂莫西．
．歐文斯
邁克爾．索思
Original Assignee
霍夫曼-拉羅奇有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 霍夫曼-拉羅奇有限公司 filed Critical 霍夫曼-拉羅奇有限公司
Publication of HK1196358A1 publication Critical patent/HK1196358A1/zh

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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
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    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Oncology (AREA)
  • Vascular Medicine (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Emergency Medicine (AREA)
  • Communicable Diseases (AREA)
HK14109767.6A 2008-06-24 2014-09-29 取代的吡啶- -酮和噠嗪- -酮 HK1196358A1 (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7527708P 2008-06-24 2008-06-24

Publications (1)

Publication Number Publication Date
HK1196358A1 true HK1196358A1 (zh) 2014-12-12

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HK11107060.7A HK1152940A1 (zh) 2008-06-24 2011-07-08 新型取代的吡啶- -酮和噠嗪- -酮
HK14109767.6A HK1196358A1 (zh) 2008-06-24 2014-09-29 取代的吡啶- -酮和噠嗪- -酮

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Country Status (25)

Country Link
US (4) US7902194B2 (zh)
EP (1) EP2297142B1 (zh)
JP (1) JP5536049B2 (zh)
KR (1) KR101299867B1 (zh)
CN (3) CN102066366B (zh)
AR (1) AR072272A1 (zh)
AU (1) AU2009264400B2 (zh)
BR (1) BRPI0914657A2 (zh)
CA (1) CA2728016C (zh)
CL (1) CL2010001483A1 (zh)
CO (1) CO6382183A2 (zh)
CR (1) CR11815A (zh)
EC (1) ECSP10010709A (zh)
ES (1) ES2552320T3 (zh)
HK (2) HK1152940A1 (zh)
IL (1) IL209141A0 (zh)
MA (1) MA32487B1 (zh)
MX (1) MX2010013191A (zh)
NZ (2) NZ588819A (zh)
PE (1) PE20100851A1 (zh)
RU (1) RU2500680C2 (zh)
TW (1) TWI396537B (zh)
UA (1) UA103327C2 (zh)
WO (1) WO2009156284A1 (zh)
ZA (1) ZA201007816B (zh)

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TW201702218A (zh) 2014-12-12 2017-01-16 美國杰克森實驗室 關於治療癌症、自體免疫疾病及神經退化性疾病之組合物及方法
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AU2009264400B2 (en) 2014-05-01
KR20110011706A (ko) 2011-02-08
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PE20100851A1 (es) 2011-01-31
US7902194B2 (en) 2011-03-08
AR072272A1 (es) 2010-08-18
US20110105479A1 (en) 2011-05-05
JP5536049B2 (ja) 2014-07-02
CN103709148B (zh) 2015-10-21
HK1152940A1 (zh) 2012-03-16
CA2728016A1 (en) 2009-12-30
US8822457B2 (en) 2014-09-02
CN102066366A (zh) 2011-05-18
WO2009156284A1 (en) 2009-12-30
RU2011101774A (ru) 2012-07-27
CL2010001483A1 (es) 2011-05-13
CA2728016C (en) 2017-02-28
US8124604B2 (en) 2012-02-28
UA103327C2 (en) 2013-10-10
IL209141A0 (en) 2011-01-31
CN102066366B (zh) 2014-04-16
ZA201007816B (en) 2011-08-31
TW201002683A (en) 2010-01-16
BRPI0914657A2 (pt) 2019-09-24
US20120129845A1 (en) 2012-05-24
EP2297142A1 (en) 2011-03-23
JP2011524404A (ja) 2011-09-01
AU2009264400A1 (en) 2009-12-30
CN103408533B (zh) 2015-08-26
ECSP10010709A (es) 2011-01-31
KR101299867B1 (ko) 2013-08-23
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CR11815A (es) 2011-01-10
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US20090318448A1 (en) 2009-12-24
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