HK1190073A1 - Chondroitinase abc for treating disc herniation abc - Google Patents

Chondroitinase abc for treating disc herniation abc

Info

Publication number
HK1190073A1
HK1190073A1 HK14103160.2A HK14103160A HK1190073A1 HK 1190073 A1 HK1190073 A1 HK 1190073A1 HK 14103160 A HK14103160 A HK 14103160A HK 1190073 A1 HK1190073 A1 HK 1190073A1
Authority
HK
Hong Kong
Prior art keywords
abc
disc herniation
chondroitinase
treating disc
treating
Prior art date
Application number
HK14103160.2A
Other languages
English (en)
Chinese (zh)
Inventor
Taiichi Sirogane
Takao Murayama
Masafumi Yaguchi
Original Assignee
Seikagaku Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seikagaku Kogyo Co Ltd filed Critical Seikagaku Kogyo Co Ltd
Publication of HK1190073A1 publication Critical patent/HK1190073A1/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/51Lyases (4)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/47Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0085Brain, e.g. brain implants; Spinal cord
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y402/00Carbon-oxygen lyases (4.2)
    • C12Y402/02Carbon-oxygen lyases (4.2) acting on polysaccharides (4.2.2)
    • C12Y402/02004Chondroitin ABC lyase (4.2.2.4), i.e. chondroitinase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y402/00Carbon-oxygen lyases (4.2)
    • C12Y402/02Carbon-oxygen lyases (4.2) acting on polysaccharides (4.2.2)
    • C12Y402/0202Chondroitin-sulfate-ABC endolyase (4.2.2.20)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y402/00Carbon-oxygen lyases (4.2)
    • C12Y402/02Carbon-oxygen lyases (4.2) acting on polysaccharides (4.2.2)
    • C12Y402/02021Chondroitin-sulfate-ABC exolyase (4.2.2.21)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Psychology (AREA)
  • Dermatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK14103160.2A 2010-12-13 2014-04-02 Chondroitinase abc for treating disc herniation abc HK1190073A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2010277490 2010-12-13
PCT/JP2011/006938 WO2012081227A1 (ja) 2010-12-13 2011-12-13 椎間板ヘルニア治療剤

Publications (1)

Publication Number Publication Date
HK1190073A1 true HK1190073A1 (en) 2014-06-27

Family

ID=46244346

Family Applications (1)

Application Number Title Priority Date Filing Date
HK14103160.2A HK1190073A1 (en) 2010-12-13 2014-04-02 Chondroitinase abc for treating disc herniation abc

Country Status (16)

Country Link
US (5) US20130266555A1 (xx)
EP (1) EP2653168B1 (xx)
JP (1) JP5465791B2 (xx)
KR (2) KR101692517B1 (xx)
CN (5) CN110101852A (xx)
BR (1) BR112013014584B1 (xx)
CA (1) CA2821244C (xx)
DK (1) DK2653168T3 (xx)
ES (1) ES2536982T3 (xx)
HK (1) HK1190073A1 (xx)
PL (1) PL2653168T3 (xx)
PT (1) PT2653168E (xx)
RU (2) RU2690185C2 (xx)
TW (1) TWI488641B (xx)
WO (1) WO2012081227A1 (xx)
ZA (1) ZA201304924B (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2821244C (en) 2010-12-13 2016-08-09 Seikagaku Corporation Chondroitinase abc for disk herniation
US20190111178A1 (en) * 2016-04-04 2019-04-18 Gu Ventures Ab Methods and compositions for the treatment of intervertebral disc herniation
KR20240011868A (ko) * 2016-04-29 2024-01-26 이노비오 파마수티컬즈, 인크. 제제의 전달을 향상시키기 위한 콘드로이티나제 및/또는 히알루로니다제의 생체내 용도
US9796970B1 (en) 2017-04-24 2017-10-24 Advantek Serum Laboratories Ltd. Production of high purity chondroitinase ABC
TW201940190A (zh) 2018-02-28 2019-10-16 日商生化學工業股份有限公司 包裝體及其製造方法
WO2019167983A1 (ja) 2018-02-28 2019-09-06 生化学工業株式会社 医薬組成物、包装体及びその製造方法
KR102270354B1 (ko) * 2018-10-08 2021-06-30 한국과학기술연구원 단결정 이종 2차원 물질의 애피택셜 성장 방법 및 적층 구조체
JP2022151423A (ja) * 2021-03-25 2022-10-07 均 石井 椎間板ヘルニア治療薬。

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4696816A (en) * 1985-11-07 1987-09-29 Brown Mark D Method for treating intervertebral disc displacement with enzymes
US5496718A (en) 1992-06-26 1996-03-05 Seikagaku Kogyo Kabushiki Kaisha (Seikagaku Corporation) Chondroitinase ABC isolated from proteus vulgaris ATCC 6896
JP3980657B2 (ja) 1992-06-26 2007-09-26 生化学工業株式会社 コンドロイチナーゼabc、その製造法及び医薬組成物
DE69829605T2 (de) * 1997-05-02 2006-02-09 Seikagaku Corp. Chondroitinase enthaltende Zusammensetzungen
US6063378A (en) 1997-08-22 2000-05-16 Seikagaku Corporation Therapeutic agent for herniated intervertebral disc
JPH11193245A (ja) * 1997-12-26 1999-07-21 Seikagaku Kogyo Co Ltd コンドロイチナーゼabc組成物
ES2478257T3 (es) * 1998-10-06 2014-07-21 Stryker Corporation Composición que comprende una proteína osteogénica seleccionada del grupo que consiste en OP-2, OP-3, BMP-2, BMP-3, BMP-4, BMP-5, BMP-6, BMP-9, BMP-10, BMP-11 , BMP-15, BMP-3B, DPP, Vg-1, Vgr-1, proteína 60A, GDF-1, GDF-2, GDF-3, GDF-6, GDF-7, GDF-8, GDF-9, GDF-10, y GDF-11 para su uso en la reparación de defectos del cartílago no articular
JP3865364B2 (ja) * 2000-10-10 2007-01-10 生化学工業株式会社 コンドロイチナーゼ画分
JP4439396B2 (ja) * 2002-06-24 2010-03-24 田辺三菱製薬株式会社 神経系細胞の製造方法
DE10308885A1 (de) * 2003-02-28 2004-09-23 Syha, Klaus, Dr. Verwendung glycosidasehaltiger Lösungen zur Behandlung von neuronalen Zellen
TW200817015A (en) * 2006-10-06 2008-04-16 Hen-Rich Cheng A method for promoting axonal re-growth and behavior recovery in spinal cord injury
EP2185165B1 (en) * 2007-08-06 2018-10-03 Mesoblast, Inc. STRO-1bright CELLS FOR USE IN TREATING CONNECTIVE TISSUE DISEASES
CN101406695A (zh) * 2007-10-08 2009-04-15 郑宏志 促进脊髓损伤中轴突再生和行为功能恢复的药物组合物
CA2721341C (en) * 2008-04-14 2016-10-11 National University Corporation Nagoya University Therapeutic agent for neurogenic pain
CA2821244C (en) 2010-12-13 2016-08-09 Seikagaku Corporation Chondroitinase abc for disk herniation

Also Published As

Publication number Publication date
US9463225B2 (en) 2016-10-11
JP5465791B2 (ja) 2014-04-09
US20170000863A1 (en) 2017-01-05
RU2015135843A3 (xx) 2019-03-26
PT2653168E (pt) 2015-04-01
WO2012081227A1 (ja) 2012-06-21
RU2015135843A (ru) 2018-12-25
US20190224289A1 (en) 2019-07-25
CN106975077A (zh) 2017-07-25
KR101692517B1 (ko) 2017-01-03
DK2653168T3 (da) 2015-04-20
US20150071896A1 (en) 2015-03-12
RU2564001C2 (ru) 2015-09-27
CN110101852A (zh) 2019-08-09
JPWO2012081227A1 (ja) 2014-05-22
CN103260636A (zh) 2013-08-21
RU2019116210A (ru) 2020-11-27
EP2653168A4 (en) 2014-06-25
US11266725B2 (en) 2022-03-08
CN111265472A (zh) 2020-06-12
TW201306860A (zh) 2013-02-16
US20130266555A1 (en) 2013-10-10
ZA201304924B (en) 2014-09-25
ES2536982T3 (es) 2015-06-01
EP2653168B1 (en) 2015-03-04
BR112013014584B1 (pt) 2020-12-01
EP2653168A1 (en) 2013-10-23
PL2653168T3 (pl) 2015-07-31
TWI488641B (zh) 2015-06-21
BR112013014584A2 (pt) 2016-09-20
CA2821244A1 (en) 2012-06-21
CN111420040A (zh) 2020-07-17
RU2013132566A (ru) 2015-01-20
US10286046B2 (en) 2019-05-14
CA2821244C (en) 2016-08-09
RU2690185C2 (ru) 2019-05-31
KR20170004032A (ko) 2017-01-10
KR20130139284A (ko) 2013-12-20
US20220160845A1 (en) 2022-05-26
US11944670B2 (en) 2024-04-02

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