HK1186732A1 - -芳基咪唑並 噠嗪、 -苯基咪唑並 吡啶、和 -苯基咪唑並 吡嗪衍生物 - Google Patents

-芳基咪唑並 噠嗪、 -苯基咪唑並 吡啶、和 -苯基咪唑並 吡嗪衍生物

Info

Publication number
HK1186732A1
HK1186732A1 HK13114185.1A HK13114185A HK1186732A1 HK 1186732 A1 HK1186732 A1 HK 1186732A1 HK 13114185 A HK13114185 A HK 13114185A HK 1186732 A1 HK1186732 A1 HK 1186732A1
Authority
HK
Hong Kong
Prior art keywords
phenylimidazo
arylimidazo
pyridazine
pyridine
pyrazine derivatives
Prior art date
Application number
HK13114185.1A
Other languages
English (en)
Inventor
羅伯特．
．阿特金森
安迪．
．奧門
詹姆士．
．斐爾
肯尼司．
．黃
艾蜜莉．
．史密斯
Original Assignee
江蘇恒瑞醫藥股份有限公司 江蘇省連雲港市
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 江蘇恒瑞醫藥股份有限公司 江蘇省連雲港市 filed Critical 江蘇恒瑞醫藥股份有限公司 江蘇省連雲港市
Publication of HK1186732A1 publication Critical patent/HK1186732A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/5025—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HK13114185.1A 2010-12-22 2013-12-23 -芳基咪唑並 噠嗪、 -苯基咪唑並 吡啶、和 -苯基咪唑並 吡嗪衍生物 HK1186732A1 (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201061426216P 2010-12-22 2010-12-22
US201161514833P 2011-08-03 2011-08-03
US201161523688P 2011-08-15 2011-08-15
PCT/US2011/066837 WO2012088411A1 (en) 2010-12-22 2011-12-22 2-arylimidazo[1,2-b]pyridazine, 2-phenylimidazo[1,2-a]pyridine, and 2-phenylimidazo[1,2-a]pyrazine derivatives

Publications (1)

Publication Number Publication Date
HK1186732A1 true HK1186732A1 (zh) 2014-03-21

Family

ID=45478596

Family Applications (1)

Application Number Title Priority Date Filing Date
HK13114185.1A HK1186732A1 (zh) 2010-12-22 2013-12-23 -芳基咪唑並 噠嗪、 -苯基咪唑並 吡啶、和 -苯基咪唑並 吡嗪衍生物

Country Status (13)

Country Link
US (1) US8871767B2 (zh)
EP (1) EP2635578B1 (zh)
JP (1) JP6088980B2 (zh)
KR (1) KR101959726B1 (zh)
CN (1) CN103261198B (zh)
AU (1) AU2011348143B2 (zh)
BR (1) BR112013015959A2 (zh)
CA (1) CA2821546C (zh)
HK (1) HK1186732A1 (zh)
MX (1) MX2013007148A (zh)
RU (1) RU2598385C2 (zh)
TW (1) TWI617559B (zh)
WO (1) WO2012088411A1 (zh)

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Publication number Publication date
CN103261198A (zh) 2013-08-21
BR112013015959A2 (pt) 2018-07-10
CN103261198B (zh) 2016-06-08
CA2821546A1 (en) 2012-06-28
AU2011348143B2 (en) 2016-09-08
RU2013133881A (ru) 2015-01-27
US8871767B2 (en) 2014-10-28
EP2635578B1 (en) 2015-12-16
TWI617559B (zh) 2018-03-11
CA2821546C (en) 2019-03-05
RU2598385C2 (ru) 2016-09-27
US20120178751A1 (en) 2012-07-12
JP2014500331A (ja) 2014-01-09
KR101959726B1 (ko) 2019-03-19
MX2013007148A (es) 2013-11-01
KR20140019311A (ko) 2014-02-14
EP2635578A1 (en) 2013-09-11
JP6088980B2 (ja) 2017-03-01
WO2012088411A1 (en) 2012-06-28
AU2011348143A1 (en) 2013-06-20
TW201307342A (zh) 2013-02-16

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