HK1248676A1 - 咪唑並[1，2-a]吡啶類化合物及其合成及使用方法 - Google Patents

咪唑並[1，2-a]吡啶類化合物及其合成及使用方法

Info

Publication number
HK1248676A1
HK1248676A1 HK18107921.9A HK18107921A HK1248676A1 HK 1248676 A1 HK1248676 A1 HK 1248676A1 HK 18107921 A HK18107921 A HK 18107921A HK 1248676 A1 HK1248676 A1 HK 1248676A1
Authority
HK
Hong Kong
Prior art keywords
imidazo
synthesis
methods
same
pyridine compounds
Prior art date
Application number
HK18107921.9A
Other languages
English (en)
Inventor
Marvin J Miller
Garrett C Moraski
Lowell D Markley
George E Davis
Original Assignee
Univ Notre Dame Du Lac
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Notre Dame Du Lac filed Critical Univ Notre Dame Du Lac
Publication of HK1248676A1 publication Critical patent/HK1248676A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/50—1,3-Diazoles; Hydrogenated 1,3-diazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Pulmonology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK18107921.9A 2009-11-05 2018-06-20 咪唑並[1，2-a]吡啶類化合物及其合成及使用方法 HK1248676A1 (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US25854909P 2009-11-05 2009-11-05

Publications (1)

Publication Number Publication Date
HK1248676A1 true HK1248676A1 (zh) 2018-10-19

Family

ID=43970798

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18107921.9A HK1248676A1 (zh) 2009-11-05 2018-06-20 咪唑並[1，2-a]吡啶類化合物及其合成及使用方法

Country Status (10)

Country Link
US (3) US9309238B2 (zh)
EP (2) EP2496578A4 (zh)
CN (3) CN110483499A (zh)
BR (1) BR112012010752B1 (zh)
HK (1) HK1248676A1 (zh)
IL (1) IL219564A (zh)
IN (1) IN2012DN04917A (zh)
RU (1) RU2608611C2 (zh)
WO (1) WO2011057145A2 (zh)
ZA (1) ZA201204028B (zh)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110483499A (zh) * 2009-11-05 2019-11-22 圣母大学 咪唑并[1,2-a]吡啶类化合物及其合成及使用方法
SG10201502109VA (en) * 2010-03-18 2015-05-28 Pasteur Institut Korea Anti-infective compounds
CN103298468A (zh) 2011-02-01 2013-09-11 协和发酵麒麟株式会社 稠环杂环衍生物
KR102104125B1 (ko) 2011-04-21 2020-05-29 재단법인 한국파스퇴르연구소 소염 화합물
BR112014009114A2 (pt) 2011-10-21 2017-04-11 Torrent Pharmaceuticals Ltd compostos, composições farmacêuticas, métodos de tratamento, usos de um composto e processo de preparação de polimorfo
WO2014021383A1 (ja) 2012-07-31 2014-02-06 協和発酵キリン株式会社 縮環複素環化合物
HUE056198T2 (hu) * 2013-08-02 2022-02-28 Pasteur Institut Korea Fertõzés elleni vegyületek
WO2015143652A1 (en) * 2014-03-26 2015-10-01 Merck Sharp & Dohme Corp. TrkA KINASE INHIBITORS,COMPOSITIONS AND METHODS THEREOF
CN103965193B (zh) * 2014-05-30 2016-04-06 浙江司太立制药股份有限公司 N-(苯氧烷基)咪唑并[1,2-a]吡啶-3-酰胺类化合物及其制备方法
CN104628721A (zh) * 2015-01-22 2015-05-20 湖南华腾制药有限公司 一种咪唑并[1,2-a]吡啶衍生物的制备方法
EP4074378A1 (en) 2015-07-02 2022-10-19 Janssen Sciences Ireland Unlimited Company Antibacterial compounds
PE20181352A1 (es) * 2015-09-17 2018-08-22 Marvin J Miller Compuestos heterociclicos que contienen bencilamina y composiciones utiles contra infeccion por micobacterias
CN109476657A (zh) 2016-06-16 2019-03-15 爱尔兰詹森科学公司 作为抗细菌剂的杂环化合物
AU2017286370B2 (en) * 2016-06-16 2021-09-09 Janssen Sciences Ireland Uc Heterocyclic compounds as antibacte rials
CN106588916A (zh) * 2016-11-21 2017-04-26 浙江司太立制药股份有限公司 N‑(苯氧乙基)咪唑并[1,2‑a]吡啶‑3‑酰胺类化合物及其制备方法
BR112019012262A2 (pt) * 2016-12-16 2019-12-03 Bayer Ag imidazopiridinas mesoiônicas para uso como inseticidas
BR112019017901A2 (pt) 2017-03-01 2020-05-12 Janssen Sciences Ireland Unlimited Company Terapia de combinação
CN108159049B (zh) * 2018-02-01 2021-01-05 中国科学院广州生物医药与健康研究院 一种吡啶类化合物的新用途
US20210009583A1 (en) * 2018-03-12 2021-01-14 University Of Notre Dame Du Lac Deuterated imidazopyridines
CN110759913B (zh) * 2018-07-26 2022-01-28 南开大学 吲哚酰腙衍生物及其制备方法和在防治植物病毒、杀菌、杀虫方面的应用
CN113480541B (zh) * 2019-03-07 2022-09-02 湖南化工研究院有限公司 咪唑并吡啶化合物及其中间体的制备方法
KR20210150405A (ko) * 2019-04-08 2021-12-10 피아이 인더스트리스 엘티디. 식물병원성 진균을 방제 또는 예방하기 위한 신규한 옥사디아졸 화합물
TW202124379A (zh) 2019-09-10 2021-07-01 日商鹽野義製藥股份有限公司 對分枝桿菌感染有用之含苄胺的５，６－雜芳族化合物
CN115073454B (zh) * 2022-08-09 2024-03-08 贵州大学 一种咪唑并吡啶-2-噁唑啉类化合物及其制备方法和应用

Family Cites Families (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2525602A1 (fr) * 1982-04-21 1983-10-28 Synthelabo Imidazo(1,2-a)pyridines, leur preparation et leur application en therapeutique
ZA839398B (en) * 1982-12-27 1985-08-28 Lilly Co Eli Substituted imidazopyrimidines-pyrazines,and-triazines
FR2593818B1 (fr) * 1986-02-05 1988-04-29 Synthelabo Derives d'acylaminomethyl-3 imidazo(1,2-a)pyridine, leur preparation et leur application en therapeutique
DE4010797A1 (de) 1990-04-04 1991-10-10 Hoechst Ag Substituierte azole, verfahren zu deren herstellung, diese enthaltende mittel und deren verwendung
DE4023215A1 (de) 1990-07-21 1992-01-23 Hoechst Ag Substituierte azole, verfahren zu deren herstellung, sie enthaltende mittel und deren verwendung
JPH0539205A (ja) 1990-12-21 1993-02-19 Takeda Chem Ind Ltd 農園芸用混合組成物
JP3026845B2 (ja) 1991-02-20 2000-03-27 日清製粉株式会社 ピペリジン誘導体
US5464843A (en) 1992-06-23 1995-11-07 G.D. Searle & Co. Imidazo[1,2-a]pyridinyldiacid compounds for cognitive enhancement and for treatment of cognitive disorders and neutrotoxic injury
US5721273A (en) * 1993-12-15 1998-02-24 Alcon Laboratories, Inc. Use of certain 9-halo-13,14-dihydroprostaglandins to treat glaucoma and ocular hypertension
WO1995028389A1 (fr) 1994-04-15 1995-10-26 Yamanouchi Pharmaceutical Co., Ltd. Compose spiro et composition medicinale issue de ce compose
CA2193223A1 (en) 1994-07-15 1996-02-01 Muneo Takatani Tricyclic compounds, their production and use
US6080767A (en) 1996-01-02 2000-06-27 Aventis Pharmaceuticals Products Inc. Substituted n-[(aminoiminomethyl or aminomethyl)phenyl]propyl amides
US6323227B1 (en) 1996-01-02 2001-11-27 Aventis Pharmaceuticals Products Inc. Substituted N-[(aminoiminomethyl or aminomethyl)phenyl]propyl amides
JPH09249666A (ja) 1996-01-12 1997-09-22 Takeda Chem Ind Ltd 三環性化合物の製造法およびその中間体
SE9700661D0 (sv) * 1997-02-25 1997-02-25 Astra Ab New compounds
AUPP278498A0 (en) * 1998-04-03 1998-04-30 Australian Nuclear Science & Technology Organisation Peripheral benzodiazepine receptor binding agents
AU4543899A (en) 1998-06-08 1999-12-30 Advanced Medicine, Inc. Multibinding inhibitors of microsomal triglyceride transferase protein
GB2351081A (en) 1999-06-18 2000-12-20 Lilly Forschung Gmbh Pharmaceutically active imidazoline compounds and analogues thereof
US6632815B2 (en) 1999-09-17 2003-10-14 Millennium Pharmaceuticals, Inc. Inhibitors of factor Xa
IL148698A0 (en) 1999-09-17 2002-09-12 Cor Therapeutics Inc INHIBITORS OF FACTOR Xa
US6403588B1 (en) * 2000-04-27 2002-06-11 Yamanouchi Pharmaceutical Co., Ltd. Imidazopyridine derivatives
CN1173975C (zh) 2000-04-27 2004-11-03 山之内制药株式会社 咪唑并吡啶衍生物
WO2002002557A2 (en) * 2000-06-30 2002-01-10 Neurogen Corporation 2-phenylimidazo[1,2-a]pyridine derivatives: a new class of gaba brain receptor ligands
GB0021670D0 (en) 2000-09-04 2000-10-18 Astrazeneca Ab Chemical compounds
DE10247269A1 (de) * 2002-10-10 2004-04-22 Grünenthal GmbH Substituierte C-Imidazo[1,2-a]pyridin-3-yl-methylamine
WO2004100868A2 (en) 2003-04-23 2004-11-25 Abbott Laboratories Method of treating transplant rejection
BRPI0418102A (pt) 2003-12-23 2007-04-27 Pfizer derivados de quinolina
CA2566184A1 (en) * 2004-05-10 2005-11-17 Banyu Pharmaceutical Co., Ltd. Imidazopyridine compound
US20060084806A1 (en) * 2004-07-21 2006-04-20 Ramasubramanian Sridharan Processes for the preparation of imidazo[1,2-a] pyridine derivatives
WO2006015737A1 (de) * 2004-08-02 2006-02-16 Schwarz Pharma Ag Carboxamide des indolizins und seiner aza- und diazaderivate
EP1814880B1 (en) * 2004-11-11 2009-01-28 Ferrer Internacional, S.A. Imidazo[1,2-a]pyridine compounds, compositions, uses and methods related thereto
DE602005026703D1 (de) * 2004-12-24 2011-04-14 Astrazeneca Ab Amidderivate
WO2007015866A2 (en) 2005-07-20 2007-02-08 Kalypsys, Inc. Inhibitors of p38 kinase and methods of treating inflammatory disorders
EP2024334A4 (en) 2006-05-18 2009-09-30 Merck & Co Inc SUBSTITUTED ESTERS AS CANNABINOID-1 RECEPTOR MODULATORS
FR2903178B1 (fr) 2006-07-03 2008-10-03 Rech S De L Ecole Nationale Su Procede et dispositif de nettoyage des surfaces de ruissellement d'eau dans un echangeur thermique air/eau
JP2010504957A (ja) * 2006-09-29 2010-02-18 アクテリオン ファーマシューティカルズ リミテッド ３−アザ−ビシクロ［３．１．０］ヘキサン誘導体
EP2068869A4 (en) * 2006-10-06 2011-05-25 Abbott Lab NEW IMIDAZOTHIAZOLE AND IMIDAZOXAZOLE
JP2010513495A (ja) * 2006-12-20 2010-04-30 シェーリング コーポレイション 新規なｊｎｋ阻害剤
EP2125816A2 (en) 2007-03-07 2009-12-02 Alantos Pharmaceuticals Holding, Inc. Metalloprotease inhibitors containing a heterocyclic moiety
EP1980251A1 (en) * 2007-04-13 2008-10-15 Glaxo Group Limited Pyrrolo[3,2,1-ij]quinoline-4-one derivatives for treating tuberculosis
TW200901969A (en) 2007-06-06 2009-01-16 Smithkline Beecham Corp Chemical compounds
US8148380B2 (en) 2007-07-23 2012-04-03 Crestone, Inc. Antibacterial amide and sulfonamide substituted heterocyclic urea compounds
CA2709784A1 (en) 2007-12-21 2009-07-09 University Of Rochester Method for altering the lifespan of eukaryotic organisms
EP2300470A2 (en) * 2008-05-19 2011-03-30 Sepracor Inc. Imidazo[1,2-a]pyridine compounds as gaba-a receptor modulators
US9066951B2 (en) 2008-05-29 2015-06-30 Wisconsin Alumni Research Foundation Drugs to treat HPV infection
JP5536773B2 (ja) 2008-08-14 2014-07-02 ベータ・ファーマ・カナダ・インコーポレイテッド Ｅｐ４受容体アンタゴニストとしてのヘテロ環式アミド誘導体
US8293909B2 (en) 2008-09-11 2012-10-23 Bristol-Myers Squibb Company Compounds for the treatment of hepatitis C
US8198449B2 (en) * 2008-09-11 2012-06-12 Bristol-Myers Squibb Company Compounds for the treatment of hepatitis C
DK2376490T3 (da) * 2008-12-04 2013-04-15 Proximagen Ltd Imidazopyridinforbindelser
WO2011050245A1 (en) 2009-10-23 2011-04-28 Yangbo Feng Bicyclic heteroaryls as kinase inhibitors
CN110483499A (zh) * 2009-11-05 2019-11-22 圣母大学 咪唑并[1,2-a]吡啶类化合物及其合成及使用方法
SG10201502109VA (en) 2010-03-18 2015-05-28 Pasteur Institut Korea Anti-infective compounds

Also Published As

Publication number Publication date
EP3257854A1 (en) 2017-12-20
IL219564A (en) 2017-01-31
WO2011057145A3 (en) 2011-09-09
ZA201204028B (en) 2013-11-27
RU2012122653A (ru) 2013-12-10
BR112012010752B1 (pt) 2021-07-20
US9309238B2 (en) 2016-04-12
EP2496578A2 (en) 2012-09-12
CN106866667B (zh) 2019-11-15
US10913737B2 (en) 2021-02-09
EP2496578A4 (en) 2013-08-21
CN110483499A (zh) 2019-11-22
RU2608611C2 (ru) 2017-01-23
US20160318925A1 (en) 2016-11-03
CN106866667A (zh) 2017-06-20
US20180354944A1 (en) 2018-12-13
CN102762556B (zh) 2017-04-26
BR112012010752A2 (pt) 2020-09-15
IL219564A0 (en) 2012-06-28
CN102762556A (zh) 2012-10-31
IN2012DN04917A (zh) 2015-09-25
US20120220457A1 (en) 2012-08-30
US9908876B2 (en) 2018-03-06
WO2011057145A2 (en) 2011-05-12

Similar Documents

Publication Publication Date Title
HK1248676A1 (zh) 咪唑並[1，2-a]吡啶類化合物及其合成及使用方法
HK1253364A1 (zh) 1h-吡唑並[3，4-b]吡啶及其治療應用
IL216609A0 (en) Preparation and uses of 1,2,4-triazolo [1,5a] pyridine derivatives
IL215074A0 (en) Substituted imidazo[1,2-a]pyridine derivatives, pharmaceutical compositions, and methods of use as beta-secretase inhibitors
ZA201106599B (en) Pyrrolo [2,3-b] pyridine derivatives for the inhibition of raf kinases
IL204720A0 (en) Imidazo [1, 2 - a] pyridine derivatives useful as alk inhibitors
IL206100A0 (en) Process for the preparation of macrocycle
IL225232A0 (en) History of imidazo[1,2–b]pyridazine and imidazo[4,5,b]pyridine as jak inhibitors
IL219424A0 (en) IMIDAZO [1,2-b] PYRIDAZINE DERIVATIVES AND THEIR USE AS PDE10 INHIBITORS
PL2334672T3 (pl) Związki 4,5,6,7-tetrahydroimidazo[4,5-C]pirydynowe jako inhibitory SSAO
ZA201105896B (en) [1,2,4] triazolo [1,5-a] pyridines as kinase inhibitors
PL2124944T3 (pl) Pochodne pirazolo[3,4-b]pirydyny jako inhibitory fosfodiesterazy
IL229993A0 (en) A process for the preparation of 8-Alkoxy[1,2,4]triazolo[5,1-c]pyrimidine-2 amines 5-converted
HK1122797A1 (en) Derivatives of pyrido
IL206673A0 (en) Imidazo[1,2-a]pyridine-2-carboxamide derivatives, their preparation and their therapeutic application
IL216794A0 (en) 3-substituted-8-substituted-3h imidazo[5,1-d][1,2,3,5]tetrazin-4-one compounds and their use
EP2300467A4 (en) NEW AND IMPROVED METHODS FOR THE MANUFACTURE OF PALIPERIDONE
IL206671A0 (en) N-HETEROCYCLIC-IMIDAZO[1,2-a]PYRIDINE-2-CARBOXAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
EP2565194A4 (en) Imidazo [1,2-A] pyridine
IL215521A0 (en) DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-a]IMIDAZOLE-3-CARBOXYLIC ACID AMIDES
ZA201004520B (en) N-phenyl-imidazo[1,2-a]pyridine-2-carboxamide compounds,preparation thereof and therapeutic application thereof
IL206665A0 (en) 2-BENZOYLIMIDAZO[1,2-a]PYRIDINE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF
IL206667A0 (en) 2-HETEROAROYLIMIDAZO[1,2-a]PYRIDINE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF
IL246841A0 (en) Bicyclic derivatives [2,2,2] and methods of use
AU2011246168A1 (en) Imidazo[1,2-a]pyridine derivative