HK1182617A1 - 用以治療血管滲透性過高的二酮哌嗪 - Google Patents

用以治療血管滲透性過高的二酮哌嗪

Info

Publication number
HK1182617A1
HK1182617A1 HK13109875.6A HK13109875A HK1182617A1 HK 1182617 A1 HK1182617 A1 HK 1182617A1 HK 13109875 A HK13109875 A HK 13109875A HK 1182617 A1 HK1182617 A1 HK 1182617A1
Authority
HK
Hong Kong
Prior art keywords
diketopiperazines
treating vascular
vascular hyperpermeability
hyperpermeability
treating
Prior art date
Application number
HK13109875.6A
Other languages
English (en)
Inventor
David Bar-Or
Original Assignee
Ampio Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ampio Pharmaceuticals Inc filed Critical Ampio Pharmaceuticals Inc
Publication of HK1182617A1 publication Critical patent/HK1182617A1/zh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK13109875.6A 2010-09-07 2013-08-23 用以治療血管滲透性過高的二酮哌嗪 HK1182617A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38040410P 2010-09-07 2010-09-07
PCT/US2011/050612 WO2012033789A2 (en) 2010-09-07 2011-09-07 Treatment of diseases

Publications (1)

Publication Number Publication Date
HK1182617A1 true HK1182617A1 (zh) 2013-12-06

Family

ID=45771136

Family Applications (1)

Application Number Title Priority Date Filing Date
HK13109875.6A HK1182617A1 (zh) 2010-09-07 2013-08-23 用以治療血管滲透性過高的二酮哌嗪

Country Status (18)

Country Link
US (3) US20120058934A1 (zh)
EP (1) EP2613795B1 (zh)
JP (2) JP5941047B2 (zh)
KR (1) KR101822951B1 (zh)
CN (1) CN103200952B (zh)
AU (1) AU2011299353B2 (zh)
BR (1) BR112013005432A8 (zh)
CA (1) CA2810834C (zh)
CO (1) CO6710904A2 (zh)
EA (1) EA023932B1 (zh)
ES (1) ES2611878T3 (zh)
HK (1) HK1182617A1 (zh)
IL (1) IL224931A (zh)
MX (1) MX343160B (zh)
NZ (1) NZ607600A (zh)
SG (2) SG10201507120TA (zh)
WO (1) WO2012033789A2 (zh)
ZA (1) ZA201301601B (zh)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1311269B1 (en) 2000-08-04 2012-02-29 DMI Biosciences, Inc. Method of using diketopiperazines and composition containing them
ES2572975T3 (es) * 2003-05-15 2016-06-03 Ampio Pharmaceuticals, Inc. Tratamiento de enfermedades mediadas por los linfocitos T
US8217047B2 (en) 2008-05-27 2012-07-10 Dmi Acquisition Corp. Therapeutic methods and compounds
SG10201507120TA (en) * 2010-09-07 2015-10-29 Ampio Pharmaceuticals Inc Treatment of diseases
JP2013537195A (ja) 2010-09-07 2013-09-30 ディエムアイ アクイジション コーポレイション 疾患の治療
CN103841987B (zh) 2011-10-10 2015-06-17 安皮奥制药股份有限公司 退行性关节病的治疗
MX2014003856A (es) 2011-10-10 2015-01-16 Ampio Pharmaceuticals Inc Dispositivos medicos implantables con tolerancia inmune incrementada y metodos para hacerlos e implantarlos.
SG10201605205VA (en) 2011-10-28 2016-08-30 Ampio Pharmaceuticals Inc Treatment of rhinitis
EP2968315B1 (en) 2013-03-15 2020-06-03 Ampio Pharmaceuticals, Inc. Compositions for the mobilization, homing, expansion and differentiation of stem cells and methods of using the same
US20160106130A1 (en) 2013-06-10 2016-04-21 Suntory Holdings Limited Plant extract containing diketopiperazine and method for producing same
CN103913853A (zh) * 2013-07-05 2014-07-09 马准吾 具备冷感包覆层的隐形眼镜
EP3183240A4 (en) 2014-08-18 2018-06-27 Ampio Pharmaceuticals, Inc. Treatment of joint conditions
US11389512B2 (en) 2015-06-22 2022-07-19 Ampio Pharmaceuticals, Inc. Use of low molecular weight fractions of human serum albumin in treating diseases
KR20180030915A (ko) 2015-07-27 2018-03-26 산토리 홀딩스 가부시키가이샤 고리형 디펩티드 및 감미료를 함유하는 조성물
KR102396603B1 (ko) 2015-09-16 2022-05-11 원광대학교산학협력단 시트룰린을 유효성분으로 함유하는 간 기능 개선용 조성물
CN105879005A (zh) * 2016-02-01 2016-08-24 四川好医生攀西药业有限责任公司 一种治疗溃疡性结肠炎的药物组合物及其制备方法和应用
CN109563150A (zh) * 2016-07-26 2019-04-02 安皮奥制药股份有限公司 由血管高通透性介导的疾病的治疗
CN111033637B (zh) 2017-08-08 2023-12-05 费森尤斯医疗保健控股公司 用于治疗和评估慢性肾脏疾病的进程的系统和方法
JP6741280B2 (ja) * 2018-03-29 2020-08-19 株式会社ウォーターエージェンシー Ace阻害、血圧上昇抑制、又は血圧降下に用いられる組成物、及びその製造方法
WO2021195265A1 (en) 2020-03-24 2021-09-30 Ampio Pharmaceuticals, Inc. Methods for treating diseases associated with respiratory viruses
CN113754598B (zh) * 2021-09-29 2023-06-06 四川大学 含环肽结构的二胺、聚酰亚胺及其制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000327575A (ja) * 1999-05-26 2000-11-28 Teika Seiyaku Kk ジケトピペラジン誘導体含有炎症疾患治療剤および新規なジケトピペラジン誘導体
EP1311269B1 (en) * 2000-08-04 2012-02-29 DMI Biosciences, Inc. Method of using diketopiperazines and composition containing them
CN1791420A (zh) * 2003-05-15 2006-06-21 Dmi生物科学公司 T-细胞介导的疾病的治疗
ES2572975T3 (es) * 2003-05-15 2016-06-03 Ampio Pharmaceuticals, Inc. Tratamiento de enfermedades mediadas por los linfocitos T
MX2010003113A (es) * 2007-09-25 2010-04-01 Abbott Lab Compuestos de octahidropentaleno como antagonistas del receptor de quimiocina.
US8217047B2 (en) * 2008-05-27 2012-07-10 Dmi Acquisition Corp. Therapeutic methods and compounds
SG10201507120TA (en) * 2010-09-07 2015-10-29 Ampio Pharmaceuticals Inc Treatment of diseases
JP2013537195A (ja) * 2010-09-07 2013-09-30 ディエムアイ アクイジション コーポレイション 疾患の治療

Also Published As

Publication number Publication date
BR112013005432A2 (pt) 2016-06-07
EP2613795A2 (en) 2013-07-17
ZA201301601B (en) 2018-12-19
JP5941047B2 (ja) 2016-06-29
BR112013005432A8 (pt) 2017-12-05
MX343160B (es) 2016-10-26
CA2810834C (en) 2017-03-21
NZ607600A (en) 2015-05-29
EP2613795A4 (en) 2013-10-30
ES2611878T3 (es) 2017-05-11
AU2011299353A1 (en) 2013-03-14
IL224931A (en) 2017-05-29
EA201390347A1 (ru) 2013-07-30
WO2012033789A2 (en) 2012-03-15
JP2013537194A (ja) 2013-09-30
CO6710904A2 (es) 2013-07-15
JP2016145261A (ja) 2016-08-12
SG10201507120TA (en) 2015-10-29
CA2810834A1 (en) 2012-03-15
US20210052578A1 (en) 2021-02-25
CN103200952A (zh) 2013-07-10
KR20140003399A (ko) 2014-01-09
WO2012033789A3 (en) 2012-05-31
US20120058934A1 (en) 2012-03-08
EP2613795B1 (en) 2016-10-26
EA023932B1 (ru) 2016-07-29
SG187986A1 (en) 2013-03-28
KR101822951B1 (ko) 2018-01-29
CN103200952B (zh) 2016-04-06
US20200016152A1 (en) 2020-01-16
AU2011299353B2 (en) 2016-02-25
MX2013002566A (es) 2013-06-18

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20200910