HK1166321A1 - 3-cycloalkylaminopyrrolidine derivatives as modulators of chemokine receptors 3- - Google Patents

3-cycloalkylaminopyrrolidine derivatives as modulators of chemokine receptors 3-

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Publication number
HK1166321A1
HK1166321A1 HK12107037.6A HK12107037A HK1166321A1 HK 1166321 A1 HK1166321 A1 HK 1166321A1 HK 12107037 A HK12107037 A HK 12107037A HK 1166321 A1 HK1166321 A1 HK 1166321A1
Authority
HK
Hong Kong
Prior art keywords
modulators
chemokine receptors
cycloalkylaminopyrrolidine derivatives
cycloalkylaminopyrrolidine
derivatives
Prior art date
Application number
HK12107037.6A
Other languages
English (en)
Chinese (zh)
Inventor
薛楚標
．邁特卡夫
．韓
．羅賓遜
鄭長勝
王安來
張迎新
Original Assignee
因賽特公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 因賽特公司 filed Critical 因賽特公司
Publication of HK1166321A1 publication Critical patent/HK1166321A1/xx

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    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/24—Radicals substituted by oxygen atoms
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
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    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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HK12107037.6A 2003-12-18 2012-07-18 3-cycloalkylaminopyrrolidine derivatives as modulators of chemokine receptors 3- HK1166321A1 (en)

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EA010027B1 (ru) * 2002-11-27 2008-06-30 Инсайт Корпорейшн Производные 3-аминопирролидина в качестве модуляторов рецепторов хемокинов
CA2562235C (fr) 2004-04-13 2013-09-24 Incyte Corporation Utilisation de derives de piperazinylpiperidine comme antagonistes de recepteurs de chimiokines
US7307086B2 (en) 2004-05-11 2007-12-11 Incyte Corporation 3-(4-heteroarylcyclohexylamino)cyclopentanecarboxamides as modulators of chemokine receptors
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