HK1160106A1 - Process for the preparation of optically active (s)-(-)-2-(n-propylamino)- 5-methoxytetraline and (s)-(-)-2-(n-propylamino)-5-hydroxytetraline compounds (s)-(-)-2-(n-)-5-(s)-(-)-2-(n- )-5- - Google Patents
Process for the preparation of optically active (s)-(-)-2-(n-propylamino)- 5-methoxytetraline and (s)-(-)-2-(n-propylamino)-5-hydroxytetraline compounds (s)-(-)-2-(n-)-5-(s)-(-)-2-(n- )-5-Info
- Publication number
- HK1160106A1 HK1160106A1 HK12100665.0A HK12100665A HK1160106A1 HK 1160106 A1 HK1160106 A1 HK 1160106A1 HK 12100665 A HK12100665 A HK 12100665A HK 1160106 A1 HK1160106 A1 HK 1160106A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- propylamino
- methoxytetraline
- preparation
- optically active
- hydroxytetraline
- Prior art date
Links
- ICJPCRXVYMMSJY-LBPRGKRZSA-N (2s)-5-methoxy-n-propyl-1,2,3,4-tetrahydronaphthalen-2-amine Chemical compound C1=CC=C(OC)C2=C1C[C@@H](NCCC)CC2 ICJPCRXVYMMSJY-LBPRGKRZSA-N 0.000 title 1
- VCYPZWCFSAHTQT-NSHDSACASA-N (6s)-6-(propylamino)-5,6,7,8-tetrahydronaphthalen-1-ol Chemical class C1=CC=C2C[C@@H](NCCC)CCC2=C1O VCYPZWCFSAHTQT-NSHDSACASA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/10—Separation; Purification; Stabilisation; Use of additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/64—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C217/74—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES200802890 | 2008-10-13 | ||
| PCT/EP2009/063207 WO2010043571A1 (en) | 2008-10-13 | 2009-10-09 | Process for the preparation of optically active (s)-(-)-2-(n-propylamino)-5-methoxytetraline and (s)-(-)-2-(n-propylamino)-5-hydroxytetraline compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1160106A1 true HK1160106A1 (en) | 2012-08-10 |
Family
ID=41728366
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK12100665.0A HK1160106A1 (en) | 2008-10-13 | 2012-01-20 | Process for the preparation of optically active (s)-(-)-2-(n-propylamino)- 5-methoxytetraline and (s)-(-)-2-(n-propylamino)-5-hydroxytetraline compounds (s)-(-)-2-(n-)-5-(s)-(-)-2-(n- )-5- |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US8604242B2 (ko) |
| EP (1) | EP2346811B1 (ko) |
| JP (1) | JP5595404B2 (ko) |
| KR (1) | KR101624760B1 (ko) |
| CN (1) | CN102143937B (ko) |
| AU (1) | AU2009305477B2 (ko) |
| BR (1) | BRPI0920645A2 (ko) |
| CA (1) | CA2735101C (ko) |
| CL (1) | CL2011000830A1 (ko) |
| ES (1) | ES2396066T3 (ko) |
| HK (1) | HK1160106A1 (ko) |
| IL (1) | IL211791A (ko) |
| MX (1) | MX2011003930A (ko) |
| PE (1) | PE20110366A1 (ko) |
| RU (1) | RU2473538C2 (ko) |
| WO (1) | WO2010043571A1 (ko) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2473538C2 (ru) | 2008-10-13 | 2013-01-27 | Интерким, С.А. | СПОСОБ ПОЛУЧЕНИЯ (S)-(-)-2-(N-ПРОПИЛАМИНО)-5-МЕТОКСИТЕТРАЛИНА И (S)-(-)-2-(N-ПРОПИЛАМИНО)-5-ГИДРОКСИТЕТРАЛИНА, ИХ СОЛИ С N-(3,5-ДИНИТРОБЕНЗОИЛ)-α-ФЕНИЛГЛИЦИНОМ, СПОСОБ ПОЛУЧЕНИЯ (6S)-(-)-5,6,7,8-ТЕТРАГИДРО-6-[ПРОПИЛ(2-ТИЕНИЛ)ЭТИЛ]АМИНО-1-НАФТОЛА (РОТИГОТИНА) (ВАРИАНТЫ) |
| JP5748848B2 (ja) | 2010-06-25 | 2015-07-15 | ウーツェーベー ファルマ ゲーエムベーハーＵｃｂ Ｐｈａｒｍａ Ｇｍｂｈ | 窒素置換（ｓ）−５−アルコキシ−２−アミノテトラリン誘導体の分割方法 |
| CN102070470A (zh) * | 2010-11-05 | 2011-05-25 | 天津药物研究院 | 制备s(-)2-(n-正丙基)胺基-5-甲氧基四氢萘的方法 |
| US8809590B2 (en) * | 2011-06-27 | 2014-08-19 | Shan Dong Luye Pharmaceutical Co., Ltd. | Method for industrially preparing nitrogen substituted amino-5,6,7,8-tetrahydronaphthol |
| EP2816030A1 (en) * | 2013-06-20 | 2014-12-24 | Duke Chem, S. A. | Process for the preparation of frovatriptan and its enantiomer |
| CN113234057B (zh) * | 2021-06-03 | 2022-12-02 | 成都工业学院 | 一种罗替戈汀的制备方法 |
| CN114805095B (zh) * | 2022-05-11 | 2023-07-21 | 上海柏狮生物科技有限公司 | 一种(s)-5-甲氧基-1,2,3,4-四氢-n-丙基-2-萘胺的制备方法 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE8004002L (sv) * | 1980-05-29 | 1981-11-30 | Arvidsson Folke Lars Erik | Terapeutiskt anvendbara tetralinderivat |
| US4657925A (en) | 1984-08-13 | 1987-04-14 | Nelson Research & Development Co. | Method and compositions for reducing the intraocular pressure of mammals |
| US4564628A (en) | 1983-01-03 | 1986-01-14 | Nelson Research & Development Co. | Substituted 2-aminotetralins |
| US4584828A (en) * | 1984-05-07 | 1986-04-29 | Bentley Robert J | Brush rake |
| US4885308A (en) | 1984-08-13 | 1989-12-05 | Nelson Research & Development Co. | Method and compositions for treatment of parkinsonism syndrome in mammals |
| US5234945A (en) | 1989-05-09 | 1993-08-10 | Whitby Research, Inc. | Method of producing body weight and food intake using a dopamine D2 receptor agonist |
| EP0483152A4 (en) * | 1989-05-09 | 1992-12-02 | Whitby Research Incorporated | A method of reducing body weight and food intake using a dopamine d2 receptor agonist |
| JP2785879B2 (ja) * | 1989-05-31 | 1998-08-13 | ジ・アップジョン・カンパニー | 治療学的に有用な２―アミノテトラリン誘導体 |
| US4968837A (en) | 1989-07-28 | 1990-11-06 | Ethyl Corporation | Resolution of racemic mixtures |
| GB8921304D0 (en) * | 1989-09-20 | 1989-11-08 | Wyeth John & Brother Ltd | New method of treatment and heterocyclic compounds used therein |
| US5442117A (en) * | 1993-12-13 | 1995-08-15 | Albemarle Corporation | Enantiomeric resolution |
| JP2002265460A (ja) * | 2000-12-28 | 2002-09-18 | Takeda Chem Ind Ltd | 光学活性２，３−ジヒドロベンゾフラン化合物の製造法 |
| WO2002053551A1 (fr) | 2000-12-28 | 2002-07-11 | Takeda Chemical Industries, Ltd. | Procede de preparation de composes a base de 2,3-dihydrobenzofurane a activite optique |
| ES2200699B1 (es) * | 2002-07-12 | 2005-10-01 | Ragactives, S.L | Procedimiento para la separacion de r(-) y s(+)-5-(2-((2-(etoxifenoxi)etil)amino)propil-2-metoxibenceno-sulfonamida. |
| DE10359528A1 (de) | 2003-12-18 | 2005-07-28 | Schwarz Pharma Ag | (S)-2-N-Propylamino-5-hydroxytetralin als D3-agonistisches Therapeutikum |
| DE10361258A1 (de) | 2003-12-24 | 2005-07-28 | Schwarz Pharma Ag | Verwendung von substituierten 2-Aminotetralinen zur vorbeugenden Behandlung von Morbus Parkinson |
| RU2473538C2 (ru) | 2008-10-13 | 2013-01-27 | Интерким, С.А. | СПОСОБ ПОЛУЧЕНИЯ (S)-(-)-2-(N-ПРОПИЛАМИНО)-5-МЕТОКСИТЕТРАЛИНА И (S)-(-)-2-(N-ПРОПИЛАМИНО)-5-ГИДРОКСИТЕТРАЛИНА, ИХ СОЛИ С N-(3,5-ДИНИТРОБЕНЗОИЛ)-α-ФЕНИЛГЛИЦИНОМ, СПОСОБ ПОЛУЧЕНИЯ (6S)-(-)-5,6,7,8-ТЕТРАГИДРО-6-[ПРОПИЛ(2-ТИЕНИЛ)ЭТИЛ]АМИНО-1-НАФТОЛА (РОТИГОТИНА) (ВАРИАНТЫ) |
-
2009
- 2009-10-09 RU RU2011119224/04A patent/RU2473538C2/ru active
- 2009-10-09 US US13/059,650 patent/US8604242B2/en active Active
- 2009-10-09 JP JP2011530500A patent/JP5595404B2/ja active Active
- 2009-10-09 KR KR1020117007359A patent/KR101624760B1/ko active IP Right Grant
- 2009-10-09 ES ES09783911T patent/ES2396066T3/es active Active
- 2009-10-09 WO PCT/EP2009/063207 patent/WO2010043571A1/en active Application Filing
- 2009-10-09 EP EP09783911A patent/EP2346811B1/en active Active
- 2009-10-09 CN CN200980134441.8A patent/CN102143937B/zh active Active
- 2009-10-09 AU AU2009305477A patent/AU2009305477B2/en active Active
- 2009-10-09 PE PE2011000650A patent/PE20110366A1/es not_active Application Discontinuation
- 2009-10-09 CA CA2735101A patent/CA2735101C/en active Active
- 2009-10-09 BR BRPI0920645A patent/BRPI0920645A2/pt not_active Application Discontinuation
- 2009-10-09 MX MX2011003930A patent/MX2011003930A/es active IP Right Grant
-
2011
- 2011-03-17 IL IL211791A patent/IL211791A/en active IP Right Grant
- 2011-04-13 CL CL2011000830A patent/CL2011000830A1/es unknown
-
2012
- 2012-01-20 HK HK12100665.0A patent/HK1160106A1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2012505183A (ja) | 2012-03-01 |
| AU2009305477A1 (en) | 2010-04-22 |
| AU2009305477B2 (en) | 2014-04-17 |
| EP2346811B1 (en) | 2012-08-15 |
| CN102143937B (zh) | 2014-07-02 |
| EP2346811A1 (en) | 2011-07-27 |
| IL211791A0 (en) | 2011-06-30 |
| BRPI0920645A2 (pt) | 2016-01-12 |
| CA2735101A1 (en) | 2010-04-22 |
| US20110152543A1 (en) | 2011-06-23 |
| KR101624760B1 (ko) | 2016-05-26 |
| RU2473538C2 (ru) | 2013-01-27 |
| WO2010043571A1 (en) | 2010-04-22 |
| MX2011003930A (es) | 2011-05-03 |
| US8604242B2 (en) | 2013-12-10 |
| KR20110069036A (ko) | 2011-06-22 |
| ES2396066T3 (es) | 2013-02-19 |
| RU2011119224A (ru) | 2012-11-20 |
| CA2735101C (en) | 2015-09-29 |
| PE20110366A1 (es) | 2011-06-20 |
| CL2011000830A1 (es) | 2012-03-30 |
| CN102143937A (zh) | 2011-08-03 |
| IL211791A (en) | 2014-06-30 |
| JP5595404B2 (ja) | 2014-09-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL196234A0 (en) | A process for the preparation of optically active cyclopropylamines | |
| IL211701A0 (en) | Process for the preparation of bendamustine | |
| IL196779A0 (en) | Process for the preparation of optically active chiral amines | |
| SG10201510576WA (en) | Optically active diazabicyclooctane derivative and process for preparing the same | |
| PL2133091T3 (pl) | Kompozycje zawierające supramolekularne układy insuliny użyteczne do leczenia cukrzycy | |
| HK1160106A1 (en) | Process for the preparation of optically active (s)-(-)-2-(n-propylamino)- 5-methoxytetraline and (s)-(-)-2-(n-propylamino)-5-hydroxytetraline compounds (s)-(-)-2-(n-)-5-(s)-(-)-2-(n- )-5- | |
| HUE038302T2 (hu) | Eljárás védett L-alanin-származékok elõállítására | |
| EP2372018A4 (en) | AQUEOUS DISPERSION FOR THE TREATMENT OF FIBERS | |
| ZA201101836B (en) | Process for the preparation of rufinamide | |
| PL2151428T3 (pl) | Nowy sposób syntezy agomelatyny | |
| ZA201006827B (en) | Carboxamide-heteroaryl derivatives for the treatment of diabetes | |
| ZA200907191B (en) | Process for the preparation of gefitiib | |
| EP2374799A4 (en) | PROCESS FOR PREPARING 4- (1-HYDROXY-1-METHYLETHYL) -2-PROPYLIMIDAZOLE-5-CARBOXYLATE | |
| IL208792A0 (en) | Process for the preparation of amides | |
| PL2344489T3 (pl) | Sposób otrzymywania winpocetyny i apowinkaminy | |
| FI20070395A (fi) | Fotokatalyyttisesti aktiivinen koostumus ja menetelmä sen valmistamiseksi | |
| IL196474A0 (en) | Improved process for the preparation of voriconazole | |
| PT2151429E (pt) | Novo processo de síntese da agomelatina | |
| IL243809A0 (en) | Process for the production of γ-ketosulfide compound and γ-ketosulfide compounds | |
| DK2245000T3 (da) | Fremgangsmåde til fremstilling af optisk aktive alfa-aminoacetaler | |
| IL213520A0 (en) | Process for the preparation of optically active compounds using transfer hydrogenation | |
| EG26332A (en) | Process for the preparation of benzonoprons | |
| EP2203441A4 (en) | PROCESS FOR OPTICALLY ACTIVE SULFOXIDE COMPOUNDS | |
| ZA201007147B (en) | Adhesive formulation and process for the treatment of reinforcing inserts | |
| EP2243769A4 (en) | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE FLUORAMINE |