PL2344489T3 - Sposób otrzymywania winpocetyny i apowinkaminy - Google Patents
Sposób otrzymywania winpocetyny i apowinkaminyInfo
- Publication number
- PL2344489T3 PL2344489T3 PL09783000T PL09783000T PL2344489T3 PL 2344489 T3 PL2344489 T3 PL 2344489T3 PL 09783000 T PL09783000 T PL 09783000T PL 09783000 T PL09783000 T PL 09783000T PL 2344489 T3 PL2344489 T3 PL 2344489T3
- Authority
- PL
- Poland
- Prior art keywords
- apovincamine
- vinpocetine
- preparation
- Prior art date
Links
- OZDNDGXASTWERN-CTNGQTDRSA-N Apovincamine Chemical compound C1=CC=C2C(CCN3CCC4)=C5[C@@H]3[C@]4(CC)C=C(C(=O)OC)N5C2=C1 OZDNDGXASTWERN-CTNGQTDRSA-N 0.000 title 1
- DDNCQMVWWZOMLN-IRLDBZIGSA-N Vinpocetine Chemical compound C1=CC=C2C(CCN3CCC4)=C5[C@@H]3[C@]4(CC)C=C(C(=O)OCC)N5C2=C1 DDNCQMVWWZOMLN-IRLDBZIGSA-N 0.000 title 1
- 229950006936 apovincamine Drugs 0.000 title 1
- OZDNDGXASTWERN-UHFFFAOYSA-N apovincamine Natural products C1=CC=C2C(CCN3CCC4)=C5C3C4(CC)C=C(C(=O)OC)N5C2=C1 OZDNDGXASTWERN-UHFFFAOYSA-N 0.000 title 1
- 229960000744 vinpocetine Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cephalosporin Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08165083A EP2168963A1 (en) | 2008-09-25 | 2008-09-25 | Process for the preparation of vinpocetine and apovincamine |
| EP09783000.4A EP2344489B1 (en) | 2008-09-25 | 2009-09-15 | Process for the preparation of vinpocetine and apovincamine |
| PCT/EP2009/061907 WO2010034647A1 (en) | 2008-09-25 | 2009-09-15 | Process for the preparation of vinpocetine and apovincamine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2344489T3 true PL2344489T3 (pl) | 2014-07-31 |
Family
ID=40291148
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL09783000T PL2344489T3 (pl) | 2008-09-25 | 2009-09-15 | Sposób otrzymywania winpocetyny i apowinkaminy |
Country Status (7)
| Country | Link |
|---|---|
| EP (2) | EP2168963A1 (pl) |
| CN (1) | CN102164921B (pl) |
| HR (1) | HRP20140340T1 (pl) |
| PL (1) | PL2344489T3 (pl) |
| RS (1) | RS53278B (pl) |
| RU (1) | RU2497823C2 (pl) |
| WO (1) | WO2010034647A1 (pl) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102875547B (zh) * | 2011-07-15 | 2015-05-27 | 海南灵康制药有限公司 | 一种长春西汀化合物及其制法 |
| CN102311432B (zh) * | 2011-08-26 | 2012-10-17 | 贺金凤 | 一种更为稳定的长春西汀化合物及其药物组合物 |
| CN102911171B (zh) * | 2012-10-15 | 2015-03-04 | 绍兴民生医药有限公司 | 一种长春西汀的半合成方法 |
| CN103040823A (zh) * | 2013-01-22 | 2013-04-17 | 杭州雷索药业有限公司 | 长春西汀在制备抗血管生成类药物中的应用 |
| CN103265541A (zh) * | 2013-06-17 | 2013-08-28 | 长沙理工大学 | 一种长春西汀中间体的合成方法 |
| CN103333166B (zh) * | 2013-06-26 | 2016-07-06 | 上海交通大学 | 利用固体酸碱催化合成长春西汀的方法 |
| CN103554102A (zh) * | 2013-11-22 | 2014-02-05 | 长沙理工大学 | 一种长春西汀的简便合成方法 |
| RU2699568C2 (ru) * | 2015-12-21 | 2019-09-06 | Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт фармакологии имени В.В. Закусова" | Лиганды транслокаторного белка TSPO, обладающие антидепрессивной и ноотропной активностью |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1132307B (it) * | 1980-08-04 | 1986-07-02 | Mora Paolo Corvi | Procedimento per la sintesi di vincamina ed alcaloidi indolici correlati |
-
2008
- 2008-09-25 EP EP08165083A patent/EP2168963A1/en not_active Withdrawn
-
2009
- 2009-09-15 HR HRP20140340AT patent/HRP20140340T1/hr unknown
- 2009-09-15 RS RS20140166A patent/RS53278B/sr unknown
- 2009-09-15 WO PCT/EP2009/061907 patent/WO2010034647A1/en not_active Ceased
- 2009-09-15 PL PL09783000T patent/PL2344489T3/pl unknown
- 2009-09-15 EP EP09783000.4A patent/EP2344489B1/en active Active
- 2009-09-15 CN CN200980137365.6A patent/CN102164921B/zh not_active Expired - Fee Related
- 2009-09-15 RU RU2011116161/04A patent/RU2497823C2/ru not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| RS53278B (sr) | 2014-08-29 |
| RU2011116161A (ru) | 2012-10-27 |
| EP2168963A1 (en) | 2010-03-31 |
| EP2344489A1 (en) | 2011-07-20 |
| WO2010034647A1 (en) | 2010-04-01 |
| CN102164921B (zh) | 2014-04-02 |
| HRP20140340T1 (hr) | 2014-05-09 |
| RU2497823C2 (ru) | 2013-11-10 |
| EP2344489B1 (en) | 2014-01-22 |
| CN102164921A (zh) | 2011-08-24 |
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