HK1148435A1 - 治療糖尿病的氧雜二氮雜蒽化合物 - Google Patents

治療糖尿病的氧雜二氮雜蒽化合物

Info

Publication number
HK1148435A1
HK1148435A1 HK11102525.7A HK11102525A HK1148435A1 HK 1148435 A1 HK1148435 A1 HK 1148435A1 HK 11102525 A HK11102525 A HK 11102525A HK 1148435 A1 HK1148435 A1 HK 1148435A1
Authority
HK
Hong Kong
Prior art keywords
oxadiazoanthracene
diabetes
compounds
treatment
oxadiazoanthracene compounds
Prior art date
Application number
HK11102525.7A
Other languages
English (en)
Inventor
‧米加裡
‧波裡塞蒂
‧約庫姆
‧桑托什
‧居澤爾
‧貝梅
‧戴維斯
Original Assignee
轉化技術製藥有限責任公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 轉化技術製藥有限責任公司 filed Critical 轉化技術製藥有限責任公司
Publication of HK1148435A1 publication Critical patent/HK1148435A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/14—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Endocrinology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
HK11102525.7A 2008-03-07 2011-03-14 治療糖尿病的氧雜二氮雜蒽化合物 HK1148435A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3459908P 2008-03-07 2008-03-07
PCT/US2009/036333 WO2009111700A2 (en) 2008-03-07 2009-03-06 Oxadiazoanthracene compounds for the treatment of diabetes

Publications (1)

Publication Number Publication Date
HK1148435A1 true HK1148435A1 (zh) 2011-09-09

Family

ID=41056666

Family Applications (1)

Application Number Title Priority Date Filing Date
HK11102525.7A HK1148435A1 (zh) 2008-03-07 2011-03-14 治療糖尿病的氧雜二氮雜蒽化合物

Country Status (18)

Country Link
US (7) US7727983B2 (zh)
EP (1) EP2262364B1 (zh)
JP (1) JP5382952B2 (zh)
KR (1) KR101616737B1 (zh)
CN (1) CN101959405B (zh)
AU (1) AU2009221722B2 (zh)
BR (1) BRPI0910282A2 (zh)
CA (1) CA2716664C (zh)
DK (1) DK2262364T3 (zh)
EA (1) EA018225B1 (zh)
ES (1) ES2567451T3 (zh)
HK (1) HK1148435A1 (zh)
IL (1) IL207570A (zh)
MA (1) MA32175B1 (zh)
MX (1) MX2010009752A (zh)
NZ (1) NZ587343A (zh)
WO (1) WO2009111700A2 (zh)
ZA (1) ZA201006367B (zh)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2009221722B2 (en) 2008-03-07 2014-12-18 Vtv Therapeutics Llc Oxadiazoanthracene compounds for the treatment of diabetes
EA023430B1 (ru) 2009-03-30 2016-06-30 виТиви ТЕРАПЬЮТИКС ЭлЭлСи Замещенные производные азоантрацена, фармацевтические композиции и способы их применения
WO2011107494A1 (de) 2010-03-03 2011-09-09 Sanofi Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
DE102010015123A1 (de) 2010-04-16 2011-10-20 Sanofi-Aventis Deutschland Gmbh Benzylamidische Diphenylazetidinone, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
US8530413B2 (en) 2010-06-21 2013-09-10 Sanofi Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
TW201215387A (en) 2010-07-05 2012-04-16 Sanofi Aventis Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
TW201221505A (en) 2010-07-05 2012-06-01 Sanofi Sa Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
TW201215388A (en) 2010-07-05 2012-04-16 Sanofi Sa (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
SG191040A1 (en) 2010-12-23 2013-08-30 Pfizer Glucagon receptor modulators
WO2012096824A1 (en) * 2011-01-12 2012-07-19 Transtech Pharma, Inc. Phenylglyoxylic acid derivatives and their preparation and use
WO2012107850A1 (en) 2011-02-08 2012-08-16 Pfizer Inc. Glucagon receptor modulator
EP2734503B1 (en) 2011-07-22 2015-09-16 Pfizer Inc. Quinolinyl glucagon receptor modulators
EP2567959B1 (en) 2011-09-12 2014-04-16 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
WO2013037390A1 (en) 2011-09-12 2013-03-21 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
EP2760862B1 (en) 2011-09-27 2015-10-21 Sanofi 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
KR102158992B1 (ko) * 2012-03-22 2020-09-23 브이티브이 테라퓨틱스 엘엘씨 소-분자 ｇｌｐ1ｒ 아고니스트의 트리스(하이드록시메틸)아미노메탄 염과 그것의 제약 조성물 및 사용
WO2014064215A1 (en) 2012-10-24 2014-05-01 INSERM (Institut National de la Santé et de la Recherche Médicale) TPL2 KINASE INHIBITORS FOR PREVENTING OR TREATING DIABETES AND FOR PROMOTING β-CELL SURVIVAL
CN104968341B (zh) * 2013-01-17 2020-06-09 Vtv治疗有限责任公司 Glp1r激动剂和二甲双胍的组合及其在制备治疗2型糖尿病和其他障碍的药物中的用途
MX2017000972A (es) * 2014-07-25 2017-07-27 Celgene Int Ii Sarl Nuevos moduladores del receptor de peptido similar a glucagon 1 (glp-1).
US10426818B2 (en) 2015-03-24 2019-10-01 Inserm (Institut National De La Sante Et De La Recherche Medicale) Method and pharmaceutical composition for use in the treatment of diabetes
JOP20190060A1 (ar) 2016-09-26 2019-03-26 Chugai Pharmaceutical Co Ltd مشتق بيرازولو بيريدين له تأثير مساعد لمستقبل glp-1
TW201925204A (zh) * 2017-11-22 2019-07-01 日商第一三共股份有限公司 稠合三環化合物
KR20210005843A (ko) 2018-05-08 2021-01-15 브이티브이 테라퓨틱스 엘엘씨 Glp1r 작용제의 치료적 용도
TW202144340A (zh) 2020-04-03 2021-12-01 大陸商江蘇恆瑞醫藥股份有限公司 稠合咪唑類衍生物、其製備方法及其在醫藥上的應用
EP4159719A1 (en) * 2020-05-28 2023-04-05 Hangzhou Zhongmeihuadong Pharmaceutical Co., Ltd. Preparation method for (s)-2-amino-3-(4-(2,3-dimethylpyridin-4-yl)phenyl)methyl propionate diacid salt
US20230348484A1 (en) * 2020-05-28 2023-11-02 Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. Method for preparing glp-1 receptor agonist free base
AU2021306414A1 (en) 2020-09-01 2023-05-04 Jiangsu Hengrui Pharmaceuticals Co., Ltd. Fused imidazole derivative, preparation method therefor, and medical use thereof
WO2022078152A1 (zh) 2020-10-12 2022-04-21 杭州中美华东制药有限公司 苯并咪唑酮类glp-1受体激动剂及其用途
CA3200245A1 (en) 2020-11-27 2022-06-02 Junjun Wu Benzimidazole derivative and preparation method therefor and medical use thereof
CN116940561A (zh) 2021-03-22 2023-10-24 杭州中美华东制药有限公司 噻吩类glp-1受体激动剂及其用途
EP4317145A1 (en) 2021-03-24 2024-02-07 Shionogi & Co., Ltd Pharmaceutical composition containing glp-1 receptor agonist having fused ring
CN117500808A (zh) * 2021-06-17 2024-02-02 杭州中美华东制药有限公司 蒽类化合物、其制备方法和医药用途
EP4361145A1 (en) 2021-06-24 2024-05-01 Hangzhou Zhongmeihuadong Pharmaceutical Co., Ltd. Glp-1 receptor agonist and composition and use thereof
CN115521320B (zh) * 2021-06-25 2023-09-05 沈阳兴齐眼药股份有限公司 一种制备普拉洛芬的方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0233728A1 (en) * 1986-02-11 1987-08-26 Takeda Chemical Industries, Ltd. 1,4-Benzoxazine derivatives their production and use
JPS6345270A (ja) * 1986-02-11 1988-02-26 Takeda Chem Ind Ltd １，４−ベンゾオキサジン誘導体，その製造法およびそれを含有する医薬用組成物
EP1336600A3 (en) * 1995-10-06 2004-07-07 Ligand Pharmaceuticals Incorporated Dimer-selective RXR modulators and methods for their use
WO2000042026A1 (en) * 1999-01-15 2000-07-20 Novo Nordisk A/S Non-peptide glp-1 agonists
MXPA02005528A (es) * 1999-12-03 2002-09-02 Kyoto Pharma Ind Compuestos heterociclicos sus sales y uso medicinal.
EP1125925A1 (en) * 2000-02-15 2001-08-22 Applied Research Systems ARS Holding N.V. Amine derivatives for the treatment of apoptosis
US20050222036A1 (en) * 2000-08-24 2005-10-06 Thomas Jefferson University Peptide compositions with effects on blood glucose
KR20050114242A (ko) * 2003-03-26 2005-12-05 액테리온 파마슈티칼 리미티드 오렉신 수용체 길항제로서 이용되는테트라하이드로이소퀴놀릴 아세트아마이드 유도체
AU2009221722B2 (en) * 2008-03-07 2014-12-18 Vtv Therapeutics Llc Oxadiazoanthracene compounds for the treatment of diabetes
EP2579888A2 (en) 2010-06-09 2013-04-17 Receptos, Inc. Novel glp-1 receptor stabilizers and modulators

Also Published As

Publication number Publication date
EP2262364A4 (en) 2012-04-04
US9120813B2 (en) 2015-09-01
CA2716664C (en) 2016-10-11
US20110039837A1 (en) 2011-02-17
US20130317015A1 (en) 2013-11-28
AU2009221722A1 (en) 2009-09-11
US7906507B2 (en) 2011-03-15
US7790714B2 (en) 2010-09-07
CN101959405A (zh) 2011-01-26
AU2009221722B2 (en) 2014-12-18
US20100324033A1 (en) 2010-12-23
EA018225B1 (ru) 2013-06-28
DK2262364T3 (en) 2016-03-21
US20140187769A1 (en) 2014-07-03
MA32175B1 (fr) 2011-03-01
KR101616737B1 (ko) 2016-05-02
ES2567451T3 (es) 2016-04-22
IL207570A0 (en) 2010-12-30
WO2009111700A3 (en) 2010-03-04
US20100197677A1 (en) 2010-08-05
JP2011513431A (ja) 2011-04-28
US20150087640A1 (en) 2015-03-26
IL207570A (en) 2014-03-31
WO2009111700A2 (en) 2009-09-11
KR20100131455A (ko) 2010-12-15
JP5382952B2 (ja) 2014-01-08
MX2010009752A (es) 2010-09-30
NZ587343A (en) 2012-05-25
EP2262364A2 (en) 2010-12-22
US8703766B2 (en) 2014-04-22
ZA201006367B (en) 2011-05-25
US8933222B2 (en) 2015-01-13
US8524708B2 (en) 2013-09-03
US20090306063A1 (en) 2009-12-10
CN101959405B (zh) 2014-07-02
US7727983B2 (en) 2010-06-01
EP2262364B1 (en) 2016-03-02
EA201071045A1 (ru) 2011-02-28
BRPI0910282A2 (pt) 2015-09-01
CA2716664A1 (en) 2009-09-11

Similar Documents

Publication Publication Date Title
HK1148435A1 (zh) 治療糖尿病的氧雜二氮雜蒽化合物
IL259475A (en) Combined therapy for the treatment of diabetes
ZA200902374B (en) Compositions useful for the treatment of diabetes
ZA201105720B (en) Compounds for the treatment of hepatitis c
EP2303021A4 (en) COMPOUNDS FOR TREATING CANCER
ZA200906129B (en) Compounds for the treatment of hepatitis c
ZA201006827B (en) Carboxamide-heteroaryl derivatives for the treatment of diabetes
EP2268285A4 (en) THERAPEUTIC COMPOUNDS
GB0806794D0 (en) Therapeutic compounds
PL2209784T3 (pl) Związki do leczenia zapalenia wątroby typu C
ZA201000923B (en) Compounds for the treatment of hepatitis c
GB0813740D0 (en) Therapeutic compounds
GB0804755D0 (en) Therapeutic compounds
IL211189A0 (en) Compounds for the treatment of peripheral neuropathies
EP2358200A4 (en) BICYCLIC AMINES SUBSTITUTED FOR THE TREATMENT OF DIABETES
IL211267A0 (en) Oxadiazole derivatives for the treatment of diabetes
EP2331099A4 (en) PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF DIABETES MELLITUS
GB0819536D0 (en) Compounds for the treatment of neoplasia
GB0817857D0 (en) Compounds for the treatment of neoplasia
GB0802903D0 (en) Treatment of diabetes
GB0814997D0 (en) Processes for the preparation of compounds
GB0809319D0 (en) The treatment of puritus
GB0821817D0 (en) Therapeutic compounds
GB0811850D0 (en) Therapeutic compounds
GB0815700D0 (en) Therapeutic compounds