HK1143559A1 - Treatment of cns disorders with trans 4-(3,4-dichlorophenyl)-1,2,3,4- tetrahydro-1-napthalenamine and its formamide - Google Patents
Treatment of cns disorders with trans 4-(3,4-dichlorophenyl)-1,2,3,4- tetrahydro-1-napthalenamine and its formamideInfo
- Publication number
- HK1143559A1 HK1143559A1 HK10110208.5A HK10110208A HK1143559A1 HK 1143559 A1 HK1143559 A1 HK 1143559A1 HK 10110208 A HK10110208 A HK 10110208A HK 1143559 A1 HK1143559 A1 HK 1143559A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- napthalenamine
- dichlorophenyl
- tetrahydro
- formamide
- trans
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/33—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C211/39—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton
- C07C211/41—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton containing condensed ring systems
- C07C211/42—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton containing condensed ring systems with six-membered aromatic rings being part of the condensed ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/14—All rings being cycloaliphatic
- C07C2602/26—All rings being cycloaliphatic the ring system containing ten carbon atoms
- C07C2602/28—Hydrogenated naphthalenes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Hematology (AREA)
- Child & Adolescent Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Obesity (AREA)
- Addiction (AREA)
- Anesthesiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US41130402P | 2002-09-16 | 2002-09-16 | |
US41130502P | 2002-09-16 | 2002-09-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1143559A1 true HK1143559A1 (en) | 2011-01-07 |
Family
ID=31998027
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK10110208.5A HK1143559A1 (en) | 2002-09-16 | 2010-10-29 | Treatment of cns disorders with trans 4-(3,4-dichlorophenyl)-1,2,3,4- tetrahydro-1-napthalenamine and its formamide |
Country Status (16)
Country | Link |
---|---|
US (6) | US7087785B2 (pt) |
EP (1) | EP1542961B1 (pt) |
JP (1) | JP4610336B2 (pt) |
KR (2) | KR101067045B1 (pt) |
CN (1) | CN101712626B (pt) |
AU (1) | AU2003272460B2 (pt) |
BR (1) | BRPI0314377B8 (pt) |
CA (1) | CA2498152C (pt) |
DK (1) | DK1542961T3 (pt) |
ES (1) | ES2431519T3 (pt) |
HK (1) | HK1143559A1 (pt) |
IL (1) | IL167319A (pt) |
MX (1) | MXPA05002700A (pt) |
NZ (1) | NZ538741A (pt) |
PT (1) | PT1542961E (pt) |
WO (1) | WO2004024669A1 (pt) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MXPA05002700A (es) * | 2002-09-16 | 2005-09-08 | Sepracor Inc | Tratamiento de trastornos del sistema nervioso central con trans 4-(3,4-diclorofenil)-1,2,3,4-tetrahidro-1-naftalenamina y su formamida. |
US8134029B2 (en) | 2002-09-16 | 2012-03-13 | Sunovion Pharmaceuticals Inc. | Treatment of CNS disorders with trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine |
EP1691811B1 (en) * | 2003-12-11 | 2014-07-23 | Sunovion Pharmaceuticals Inc. | Combination of a sedative and a neurotransmitter modulator, and methods for improving sleep quality and treating depression |
PL380887A1 (pl) * | 2003-12-29 | 2007-04-02 | Sepracor Inc. | Pirolowe i pirazolowe inhibitory DAAO |
US20060199739A1 (en) * | 2005-03-02 | 2006-09-07 | Olav Messerschmidt | Limonene-containing herbicide compositions, herbicide concentrate formulations and methods for making and using same |
EP1904066B1 (en) * | 2005-07-06 | 2018-05-23 | Sunovion Pharmaceuticals Inc. | COMBINATIONS OF ESZOPICLONE AND TRANS 4-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDRO-N-METHYL-1-NAPTHALENAMINE OR TRANS 4-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDRO-1-NAPTHALENAMINE, for treating MENOPAUSE, perimenopause AND COGNITIVE DISORDERS |
JP2009522721A (ja) * | 2005-12-29 | 2009-06-11 | ユーティーシー パワー コーポレイション | ガス輸送式燃料電池冷媒の循環 |
US20070203111A1 (en) | 2006-01-06 | 2007-08-30 | Sepracor Inc. | Cycloalkylamines as monoamine reuptake inhibitors |
CN104276955A (zh) | 2006-01-06 | 2015-01-14 | 赛诺维信制药公司 | 基于四氢萘酮的单胺再摄取抑制剂 |
AU2013211500B2 (en) * | 2006-03-31 | 2016-08-04 | Sepracor Inc | Preparation of chiral amides and amines |
ES2555315T3 (es) * | 2006-03-31 | 2015-12-30 | Sunovion Pharmaceuticals Inc. | Preparación de amidas y aminas quirales |
WO2007143267A2 (en) * | 2006-05-31 | 2007-12-13 | Sepracor Inc. | Treatment of pain disorders with trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine and its formamide |
US7884124B2 (en) * | 2006-06-30 | 2011-02-08 | Sepracor Inc. | Fluoro-substituted inhibitors of D-amino acid oxidase |
US7579370B2 (en) * | 2006-06-30 | 2009-08-25 | Sepracor Inc. | Fused heterocycles |
KR101329658B1 (ko) * | 2006-09-25 | 2013-11-14 | 아처 다니엘 미드랜드 캄파니 | 초흡수성 표면처리된 카르복시알킬화 다당류 및 그 제조방법 |
US20080082066A1 (en) * | 2006-10-02 | 2008-04-03 | Weyerhaeuser Co. | Crosslinked carboxyalkyl cellulose fibers having non-permanent and temporary crosslinks |
US8138377B2 (en) * | 2006-11-07 | 2012-03-20 | Dov Pharmaceutical, Inc. | Arylbicyclo[3.1.0]hexylamines and methods and compositions for their preparation and use |
FR2909376A1 (fr) * | 2006-11-30 | 2008-06-06 | Cerep Sa | Procedes de preparation de la desmethulsertraline ou d'un de ses sels pharmaceutiquement acceptables |
US7902252B2 (en) * | 2007-01-18 | 2011-03-08 | Sepracor, Inc. | Inhibitors of D-amino acid oxidase |
CA2676432A1 (en) * | 2007-01-18 | 2008-07-24 | Sepracor, Inc. | Inhibitors of d-amino acid oxidase |
MX2009012685A (es) | 2007-05-31 | 2009-12-14 | Sepracor Inc | Cicloalquilaminas sustituidas con fenilo como inhibidores de la reabsorcion de monoamina. |
WO2010017418A1 (en) * | 2008-08-07 | 2010-02-11 | Sepracor Inc. | Prodrugs of fused heterocyclic inhibitors of d-amino acid oxidase |
JP2012526832A (ja) * | 2009-05-13 | 2012-11-01 | スノビオン プハルマセウトイカルス インコーポレイテッド | トランスノルセルトラリン及びセロトニン受容体1a作動剤/拮抗剤を含む組成物及びその使用 |
WO2011017634A2 (en) * | 2009-08-07 | 2011-02-10 | Sepracore Inc. | Prodrugs of fused heterocyclic inhibitors of d-amino acid oxidase |
MX339619B (es) * | 2009-12-04 | 2016-06-02 | Sunovion Pharmaceuticals Inc | Formulaciones, sales y polimorfos de transnorsertralina y usos de los mismos. |
WO2012158892A2 (en) | 2011-05-19 | 2012-11-22 | Bruce Roseman | A method of treating apraxia of speech in children |
US20140163070A1 (en) | 2012-05-17 | 2014-06-12 | Bruce Roseman | Treatment for cerebral palsy impaired speech in children |
US9220712B2 (en) | 2011-05-19 | 2015-12-29 | Gilrose Pharmaceuticals, Llc | Pharmaceutical intervention and method for treating an apraxia of speech in children |
US9682073B2 (en) | 2011-05-19 | 2017-06-20 | Gilrose Pharmaceuticals, Llc | Pre-frontal cortex processing disorder gait and limb impairments treatment |
US8883815B2 (en) | 2011-05-19 | 2014-11-11 | Gilrose Pharmaceuticals, Llc | Treatment for cerebral palsy impaired speech in children |
US10085414B2 (en) | 2011-05-19 | 2018-10-02 | Gilrose Pharmaceuticals, Llc | Pre-frontal cortex processing disorder speech, gait and limb impairments treatment |
WO2015175514A1 (en) * | 2014-05-13 | 2015-11-19 | Sunovion Pharmaceuticals Inc. | Methods and compositions of dasotraline for treatment of adhd |
US10076503B2 (en) | 2014-05-13 | 2018-09-18 | Sunovion Pharmaceuticals Inc. | Dosage of dasotraline and method for treatment of ADHD |
WO2016046669A2 (en) * | 2014-09-27 | 2016-03-31 | Mohan M Alapati | Compositions and methods for the treatment of depression and neurological diseases |
WO2019143920A1 (en) | 2018-01-19 | 2019-07-25 | Sunovion Pharmaceuticals Inc. | Oral dosage forms |
US20210386689A1 (en) | 2018-10-31 | 2021-12-16 | Sunovion Pharmaceuticals Inc. | Methods of treating central nervous system disorders |
EP3800178A1 (en) | 2019-10-01 | 2021-04-07 | Moehs Ibérica, S.L. | Preparation of enamide intermediate for the synthesis of dasotraline |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4556676A (en) * | 1979-11-01 | 1985-12-03 | Pfizer Inc. | Antidepressant derivatives of trans-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine |
JPS59497B2 (ja) * | 1979-11-01 | 1984-01-07 | フアイザ−・インコ−ポレ−テツド | トランス−4−フエニル−1,2,3,4−テトラヒドロ−1−ナフタレンアミンの抗抑うつ性誘導体 |
US4981870A (en) * | 1989-03-07 | 1991-01-01 | Pfizer Inc. | Use of 4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine derivatives in the treatment of psychosis, inflammation and as immunosuppressants |
US5554383A (en) * | 1995-04-06 | 1996-09-10 | Trustees Of Tufts College | Veterinary method for clinically modifying the behavior of dogs exhibiting canine affective aggression |
US5778986A (en) * | 1997-08-05 | 1998-07-14 | Davis; Floyd A. | Device to remove divots |
US6245782B1 (en) * | 1999-05-17 | 2001-06-12 | Heartdrug Research L.L.C. | Methods of inhibiting platelet activation with selective serotonin reuptake inhibitors |
MXPA05002700A (es) * | 2002-09-16 | 2005-09-08 | Sepracor Inc | Tratamiento de trastornos del sistema nervioso central con trans 4-(3,4-diclorofenil)-1,2,3,4-tetrahidro-1-naftalenamina y su formamida. |
-
2003
- 2003-09-16 MX MXPA05002700A patent/MXPA05002700A/es active IP Right Grant
- 2003-09-16 DK DK03754641.3T patent/DK1542961T3/da active
- 2003-09-16 ES ES03754641T patent/ES2431519T3/es not_active Expired - Lifetime
- 2003-09-16 WO PCT/US2003/029110 patent/WO2004024669A1/en active Application Filing
- 2003-09-16 CA CA2498152A patent/CA2498152C/en not_active Expired - Fee Related
- 2003-09-16 NZ NZ538741A patent/NZ538741A/en not_active IP Right Cessation
- 2003-09-16 US US10/663,173 patent/US7087785B2/en not_active Expired - Lifetime
- 2003-09-16 CN CN2009102541788A patent/CN101712626B/zh not_active Expired - Fee Related
- 2003-09-16 PT PT37546413T patent/PT1542961E/pt unknown
- 2003-09-16 KR KR1020057004420A patent/KR101067045B1/ko active IP Right Grant
- 2003-09-16 KR KR1020117017571A patent/KR101165549B1/ko active IP Right Grant
- 2003-09-16 AU AU2003272460A patent/AU2003272460B2/en not_active Ceased
- 2003-09-16 EP EP03754641.3A patent/EP1542961B1/en not_active Expired - Lifetime
- 2003-09-16 BR BRPI0314377A patent/BRPI0314377B8/pt not_active IP Right Cessation
- 2003-09-16 JP JP2004536572A patent/JP4610336B2/ja not_active Expired - Fee Related
-
2005
- 2005-03-08 IL IL167319A patent/IL167319A/en active IP Right Grant
- 2005-09-07 US US11/220,891 patent/US7105699B2/en not_active Expired - Lifetime
-
2006
- 2006-01-24 US US11/338,191 patent/US20060128993A1/en not_active Abandoned
- 2006-05-03 US US11/416,586 patent/US7423179B2/en not_active Expired - Lifetime
-
2008
- 2008-07-15 US US12/173,626 patent/US7589237B2/en not_active Expired - Lifetime
-
2009
- 2009-08-10 US US12/538,583 patent/US7790772B2/en not_active Expired - Lifetime
-
2010
- 2010-10-29 HK HK10110208.5A patent/HK1143559A1/xx not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20220911 |