HK1140820A1 - A high sensivity multiparameter method for rare event analysis in a biological sample - Google Patents
A high sensivity multiparameter method for rare event analysis in a biological sampleInfo
- Publication number
- HK1140820A1 HK1140820A1 HK10107242.9A HK10107242A HK1140820A1 HK 1140820 A1 HK1140820 A1 HK 1140820A1 HK 10107242 A HK10107242 A HK 10107242A HK 1140820 A1 HK1140820 A1 HK 1140820A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- biological sample
- event analysis
- rare event
- multiparameter method
- high sensivity
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/6456—Spatial resolved fluorescence measurements; Imaging
- G01N21/6458—Fluorescence microscopy
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5094—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for blood cell populations
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/533—Production of labelled immunochemicals with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57488—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds identifable in body fluids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
- G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
- G01N2021/6441—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks with two or more labels
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Physiology (AREA)
- Optics & Photonics (AREA)
- Ecology (AREA)
- Virology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12/181,399 US9134237B2 (en) | 2005-09-20 | 2008-07-29 | High sensitivity multiparameter method for rare event analysis in a biological sample |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1140820A1 true HK1140820A1 (en) | 2010-10-22 |
Family
ID=41611032
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK10107242.9A HK1140820A1 (en) | 2008-07-29 | 2010-07-28 | A high sensivity multiparameter method for rare event analysis in a biological sample |
Country Status (15)
Country | Link |
---|---|
US (1) | US9134237B2 (pl) |
EP (1) | EP2169387B1 (pl) |
JP (1) | JP6109464B2 (pl) |
KR (2) | KR101764597B1 (pl) |
CN (1) | CN101672779B (pl) |
BR (2) | BRPI0902559A2 (pl) |
CA (2) | CA2674187C (pl) |
DK (1) | DK2169387T3 (pl) |
ES (1) | ES2542061T3 (pl) |
HK (1) | HK1140820A1 (pl) |
HU (1) | HUE026779T2 (pl) |
IL (1) | IL199798A (pl) |
MX (1) | MX2009008060A (pl) |
PL (1) | PL2169387T3 (pl) |
PT (1) | PT2169387E (pl) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
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US9127302B2 (en) | 2005-09-20 | 2015-09-08 | Janssen Diagnostics, Llc | System for the detection and enumeration of suspect target cells in a mixed cell population |
US20120276555A1 (en) | 2009-10-21 | 2012-11-01 | Peter Kuhn | Method of Using Non-Rare Cells to Detect Rare Cells |
US10047398B2 (en) | 2010-10-06 | 2018-08-14 | Fundacio Institut De Recerca Biomedica (Irb Barcelona) | Method for the diagnosis, prognosis and treatment of breast cancer metastasis |
US10114020B2 (en) | 2010-10-11 | 2018-10-30 | Mbio Diagnostics, Inc. | System and device for analyzing a fluidic sample |
WO2013031365A1 (ja) * | 2011-08-30 | 2013-03-07 | オリンパス株式会社 | 標的粒子の検出方法 |
WO2013072571A1 (fr) * | 2011-11-17 | 2013-05-23 | Institut Gustave Roussy | Methode de caracterisation de cellules tumorales circulantes et application au diagnostic |
EP2650682A1 (en) | 2012-04-09 | 2013-10-16 | Fundació Privada Institut de Recerca Biomèdica | Method for the prognosis and treatment of cancer metastasis |
JP6386450B2 (ja) | 2012-06-06 | 2018-09-05 | フンダシオ、インスティトゥト、デ、レセルカ、ビオメディカ(イエレベ、バルセロナ)Fundacio Institut De Recerca Biomedica (Irb Barcelona) | 肺がん転移の診断、予後診断および処置のための方法 |
US10119171B2 (en) | 2012-10-12 | 2018-11-06 | Inbiomotion S.L. | Method for the diagnosis, prognosis and treatment of prostate cancer metastasis |
US20140105918A1 (en) | 2012-10-12 | 2014-04-17 | Inbiomotion S.L. | Method for the diagnosis, prognosis and treatment of prostate cancer metastasis |
US9739714B2 (en) | 2012-10-29 | 2017-08-22 | Mbio Diagnostics, Inc. | Particle identification system, cartridge and associated methods |
EA201691496A1 (ru) | 2014-01-27 | 2016-12-30 | Эпик Сайенсиз, Инк. | Диагностика биомаркеров рака предстательной железы с помощью циркулирующих опухолевых клеток |
EP3108246B1 (en) * | 2014-02-21 | 2019-10-09 | Epic Sciences, Inc. | Methods for analyzing rare circulating cells |
EP3186397B1 (en) * | 2014-08-25 | 2024-02-07 | Creatv Microtech, Inc. | Use of circulating cell biomarkers in the blood for detection and diagnosis of diseases and methods of isolating them |
US10793642B2 (en) | 2014-12-11 | 2020-10-06 | Inbiomotion S.L. | Binding members for human c-MAF |
US10078778B2 (en) * | 2015-01-15 | 2018-09-18 | Massachusetts Institute Of Technology | Systems, methods, and apparatus for in vitro single-cell identification and recovery |
GB201507202D0 (en) | 2015-04-28 | 2015-06-10 | Stfc Science & Technology | Receptor tyosine kinase biomarkers |
CN108474025A (zh) * | 2016-01-07 | 2018-08-31 | 克里维提夫微技术公司 | 采用依次荧光淬灭和重新染色的生物样品的多表型分型 |
PT3458610T (pt) | 2016-05-25 | 2021-06-29 | Inbiomotion Sl | Tratamento terapêutico de cancro da mama baseado no estado de c-maf |
US11353400B2 (en) * | 2016-07-19 | 2022-06-07 | Altius Institute For Biomedical Sciences | Methods for fluorescence imaging microscopy and Nano-FISH |
CN111565725A (zh) | 2017-11-22 | 2020-08-21 | 生物运动有限公司 | 基于c-maf状态的乳腺癌的治疗性处理 |
CN111330311B (zh) * | 2020-02-13 | 2021-02-23 | 浙江大学 | 一种相变诱导靶标富集的方法 |
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WO1995031481A1 (en) * | 1994-05-18 | 1995-11-23 | The Research And Development Institute, Inc. | Simple, rapid method for the detection, identification and enumeration of specific viable microorganisms |
EP0760008A1 (en) | 1994-05-19 | 1997-03-05 | Dako A/S | Pna probes for detection of neisseria gonorrhoeae and chlamydia trachomatis |
WO1997038313A1 (en) | 1996-04-05 | 1997-10-16 | The Johns Hopkins University | A method of enriching rare cells |
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EP1722230A3 (en) | 2005-04-27 | 2009-05-27 | MPB MelTec Patent- und Beteiligungsgesellschaft mbH | Method for detection of a disease-specific combinatorial molecular pattern motif in a tissue sample of a patient's skin |
US9127302B2 (en) | 2005-09-20 | 2015-09-08 | Janssen Diagnostics, Llc | System for the detection and enumeration of suspect target cells in a mixed cell population |
WO2008051478A2 (en) * | 2006-10-19 | 2008-05-02 | Chemimage Corporation | Photobleaching by high power pulses |
-
2008
- 2008-07-29 US US12/181,399 patent/US9134237B2/en active Active
-
2009
- 2009-07-09 IL IL199798A patent/IL199798A/en not_active IP Right Cessation
- 2009-07-24 CA CA2674187A patent/CA2674187C/en not_active Expired - Fee Related
- 2009-07-24 CA CA2975186A patent/CA2975186A1/en not_active Abandoned
- 2009-07-27 BR BRPI0902559-6A patent/BRPI0902559A2/pt not_active IP Right Cessation
- 2009-07-27 BR BR122018015761A patent/BR122018015761B8/pt not_active IP Right Cessation
- 2009-07-28 EP EP20090251888 patent/EP2169387B1/en not_active Not-in-force
- 2009-07-28 HU HUE09251888A patent/HUE026779T2/en unknown
- 2009-07-28 DK DK09251888.5T patent/DK2169387T3/en active
- 2009-07-28 JP JP2009175045A patent/JP6109464B2/ja active Active
- 2009-07-28 ES ES09251888.5T patent/ES2542061T3/es active Active
- 2009-07-28 PL PL09251888T patent/PL2169387T3/pl unknown
- 2009-07-28 PT PT92518885T patent/PT2169387E/pt unknown
- 2009-07-29 MX MX2009008060A patent/MX2009008060A/es active IP Right Grant
- 2009-07-29 KR KR1020090069697A patent/KR101764597B1/ko active IP Right Grant
- 2009-07-29 CN CN200910164675.9A patent/CN101672779B/zh not_active Expired - Fee Related
-
2010
- 2010-07-28 HK HK10107242.9A patent/HK1140820A1/xx not_active IP Right Cessation
-
2017
- 2017-07-27 KR KR1020170095373A patent/KR20170094523A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CN101672779A (zh) | 2010-03-17 |
EP2169387A3 (en) | 2011-03-09 |
IL199798A (en) | 2014-08-31 |
PT2169387E (pt) | 2015-06-03 |
BR122018015761B8 (pt) | 2021-07-27 |
US9134237B2 (en) | 2015-09-15 |
CA2674187C (en) | 2017-09-12 |
KR20170094523A (ko) | 2017-08-18 |
MX2009008060A (es) | 2010-07-01 |
CN101672779B (zh) | 2016-01-06 |
CA2674187A1 (en) | 2010-01-29 |
BR122018015761B1 (pt) | 2019-10-22 |
JP2010029187A (ja) | 2010-02-12 |
DK2169387T3 (en) | 2015-05-26 |
EP2169387B1 (en) | 2015-04-22 |
ES2542061T3 (es) | 2015-07-30 |
CA2975186A1 (en) | 2010-01-29 |
HUE026779T2 (en) | 2016-07-28 |
IL199798A0 (en) | 2010-05-17 |
JP6109464B2 (ja) | 2017-04-05 |
EP2169387A2 (en) | 2010-03-31 |
KR20100012847A (ko) | 2010-02-08 |
BRPI0902559A2 (pt) | 2011-04-05 |
US20090029378A1 (en) | 2009-01-29 |
PL2169387T3 (pl) | 2015-09-30 |
KR101764597B1 (ko) | 2017-08-03 |
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