HK1137438A1 - Polymorphic forms of a macrocyclic inhibitor of hcv hcv - Google Patents
Polymorphic forms of a macrocyclic inhibitor of hcv hcvInfo
- Publication number
- HK1137438A1 HK1137438A1 HK10101152.0A HK10101152A HK1137438A1 HK 1137438 A1 HK1137438 A1 HK 1137438A1 HK 10101152 A HK10101152 A HK 10101152A HK 1137438 A1 HK1137438 A1 HK 1137438A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- hcv
- polymorphic forms
- macrocyclic inhibitor
- macrocyclic
- inhibitor
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07101563 | 2007-02-01 | ||
PCT/EP2008/051268 WO2008092954A2 (fr) | 2007-02-01 | 2008-02-01 | Formes polymorphes d'un inhibiteur macrocyclique de hcv |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1137438A1 true HK1137438A1 (en) | 2010-07-30 |
Family
ID=38229348
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK10101152.0A HK1137438A1 (en) | 2007-02-01 | 2010-02-03 | Polymorphic forms of a macrocyclic inhibitor of hcv hcv |
HK15105950.0A HK1205125A1 (en) | 2007-02-01 | 2015-06-23 | Polymorphic forms of a macrocyclic inhibitor of hcv hcv |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK15105950.0A HK1205125A1 (en) | 2007-02-01 | 2015-06-23 | Polymorphic forms of a macrocyclic inhibitor of hcv hcv |
Country Status (25)
Country | Link |
---|---|
US (1) | US8143402B2 (fr) |
EP (1) | EP2118098B1 (fr) |
JP (1) | JP5523110B2 (fr) |
KR (1) | KR101580226B1 (fr) |
CN (3) | CN101589040A (fr) |
AR (2) | AR065136A1 (fr) |
AU (1) | AU2008209696B2 (fr) |
BR (1) | BRPI0806945A2 (fr) |
CA (1) | CA2677170C (fr) |
CL (1) | CL2008000321A1 (fr) |
CY (1) | CY1116339T1 (fr) |
DK (1) | DK2118098T3 (fr) |
ES (1) | ES2524784T3 (fr) |
HK (2) | HK1137438A1 (fr) |
HR (1) | HRP20141137T1 (fr) |
IL (1) | IL199215A (fr) |
MX (1) | MX2009008275A (fr) |
NZ (1) | NZ577568A (fr) |
PL (1) | PL2118098T3 (fr) |
PT (1) | PT2118098E (fr) |
RU (1) | RU2533830C2 (fr) |
SI (1) | SI2118098T1 (fr) |
TW (1) | TWI423968B (fr) |
WO (1) | WO2008092954A2 (fr) |
ZA (1) | ZA200905377B (fr) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MY140680A (en) | 2002-05-20 | 2010-01-15 | Bristol Myers Squibb Co | Hepatitis c virus inhibitors |
PE20070211A1 (es) | 2005-07-29 | 2007-05-12 | Medivir Ab | Compuestos macrociclicos como inhibidores del virus de hepatitis c |
US8207341B2 (en) | 2008-09-04 | 2012-06-26 | Bristol-Myers Squibb Company | Process or synthesizing substituted isoquinolines |
UY32099A (es) | 2008-09-11 | 2010-04-30 | Enanta Pharm Inc | Inhibidores macrocíclicos de serina proteasas de hepatitis c |
SG173772A1 (en) * | 2009-02-27 | 2011-09-29 | Ortho Mcneil Janssen Pharm | Amorphous salt of a macrocyclic inhibitor of hcv |
JP2012523419A (ja) | 2009-04-08 | 2012-10-04 | イデニク プハルマセウティカルス,インコーポレイテッド | 大環状セリンプロテアーゼ阻害剤 |
CA2769652A1 (fr) | 2009-08-05 | 2011-02-10 | Idenix Pharmaceuticals, Inc. | Inhibiteurs macrocycliques de la serine protease macrocyclique utiles contre les infections virales, en particulier le virus de l?hepatite c |
AU2011209051B2 (en) | 2010-01-27 | 2015-01-15 | AB Pharma Ltd. | Polyheterocyclic compounds highly potent as HCV inhibitors |
SG191759A1 (en) | 2010-12-30 | 2013-08-30 | Enanta Pharm Inc | Phenanthridine macrocyclic hepatitis c serine protease inhibitors |
CA2822556A1 (fr) | 2010-12-30 | 2012-07-05 | Enanta Pharmaceuticals, Inc | Inhibiteurs macrocycliques de serine protease d'hepatite c |
US9353100B2 (en) | 2011-02-10 | 2016-05-31 | Idenix Pharmaceuticals Llc | Macrocyclic serine protease inhibitors, pharmaceutical compositions thereof, and their use for treating HCV infections |
CN103501608A (zh) * | 2011-05-04 | 2014-01-08 | 默沙东公司 | 药用物质、药物组合物和制备它们的方法 |
US8957203B2 (en) | 2011-05-05 | 2015-02-17 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
US10201584B1 (en) | 2011-05-17 | 2019-02-12 | Abbvie Inc. | Compositions and methods for treating HCV |
US8691757B2 (en) | 2011-06-15 | 2014-04-08 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
WO2012171332A1 (fr) | 2011-06-16 | 2012-12-20 | 爱博新药研发(上海)有限公司 | Composé hétérocyclique macrocyclique pour l'inhibition du virus de l'hépatite c, sa préparation et ses applications |
AU2012307527B2 (en) * | 2011-09-16 | 2017-07-20 | Sanofi | Aniline derivatives,their preparation and their therapeutic application |
US8466159B2 (en) | 2011-10-21 | 2013-06-18 | Abbvie Inc. | Methods for treating HCV |
JP5677645B2 (ja) | 2011-10-21 | 2015-02-25 | アッヴィ・インコーポレイテッド | 少なくとも2種の直接作用型抗ウイルス剤、およびリバビリンを含むがインターフェロンを含まない、hcvを治療するための方法 |
US8492386B2 (en) | 2011-10-21 | 2013-07-23 | Abbvie Inc. | Methods for treating HCV |
CN104436197A (zh) | 2011-10-21 | 2015-03-25 | 艾伯维公司 | 至少两种直接作用抗病毒剂的组合产品 |
BR112015007879A2 (pt) | 2012-10-19 | 2017-07-04 | Bristol Myers Squibb Co | inibidores do vírus da hepatite c |
US9643999B2 (en) | 2012-11-02 | 2017-05-09 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
US9334279B2 (en) | 2012-11-02 | 2016-05-10 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
WO2014070964A1 (fr) | 2012-11-02 | 2014-05-08 | Bristol-Myers Squibb Company | Inhibiteurs du virus de l'hépatite c |
EP2914614B1 (fr) | 2012-11-05 | 2017-08-16 | Bristol-Myers Squibb Company | Inhibiteurs du virus de l'hépatite c |
US9580463B2 (en) | 2013-03-07 | 2017-02-28 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
WO2015103490A1 (fr) | 2014-01-03 | 2015-07-09 | Abbvie, Inc. | Formes galéniques antivirales solides |
WO2015109925A1 (fr) * | 2014-01-21 | 2015-07-30 | 杭州普晒医药科技有限公司 | Forme cristalline de médicament contre l'hépatite c et son procédé de préparation, sa composition pharmaceutique et son utilisation |
CN105308043B (zh) * | 2014-05-29 | 2018-01-30 | 杭州普晒医药科技有限公司 | 丙型肝炎药物的晶型及其制备方法、其药物组合物和用途 |
CZ2015220A3 (cs) * | 2015-03-27 | 2016-10-05 | Zentiva, K.S. | Amorfní sůl makrocyklického inhibitoru viru hepatitidy C |
WO2016177625A1 (fr) | 2015-05-04 | 2016-11-10 | Sandoz Ag | Siméprévir potassique amorphe |
CN105503851B (zh) * | 2015-12-09 | 2017-06-23 | 重庆润生科技有限公司 | 一种烯基噻唑衍生物的制备方法 |
EP3448392A4 (fr) | 2016-04-28 | 2020-01-15 | Emory University | Compositions thérapeutiques à base de nucléotides et nucléosides contenant un alcyne et utilisations associées |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1590442A4 (fr) * | 2003-02-07 | 2007-07-18 | Enanta Pharm Inc | Inhibiteurs macrocycliques de la serine protease de l'hepatite c |
BRPI0414814A (pt) * | 2003-09-26 | 2006-11-14 | Schering Corp | inibidores macrocìclicos de protease de serina ns3 de vìrus de hepatite c |
WO2005037214A2 (fr) * | 2003-10-14 | 2005-04-28 | Intermune, Inc. | Acylsulfonamides et acides carboxyliques macrocycliques utilises en tant qu'inhibiteurs de la replication du virus de l'hepatite c |
RS51243B (sr) * | 2004-01-30 | 2010-12-31 | Medivir Ab. | Inhibitori ns-3 serina hcv proteaze |
PE20070211A1 (es) * | 2005-07-29 | 2007-05-12 | Medivir Ab | Compuestos macrociclicos como inhibidores del virus de hepatitis c |
-
2008
- 2008-02-01 ES ES08708575.9T patent/ES2524784T3/es active Active
- 2008-02-01 AR ARP080100427A patent/AR065136A1/es not_active Application Discontinuation
- 2008-02-01 AU AU2008209696A patent/AU2008209696B2/en not_active Ceased
- 2008-02-01 WO PCT/EP2008/051268 patent/WO2008092954A2/fr active Application Filing
- 2008-02-01 PL PL08708575T patent/PL2118098T3/pl unknown
- 2008-02-01 TW TW097103909A patent/TWI423968B/zh not_active IP Right Cessation
- 2008-02-01 PT PT87085759T patent/PT2118098E/pt unknown
- 2008-02-01 EP EP08708575.9A patent/EP2118098B1/fr not_active Not-in-force
- 2008-02-01 DK DK08708575.9T patent/DK2118098T3/en active
- 2008-02-01 CN CNA2008800030601A patent/CN101589040A/zh active Pending
- 2008-02-01 CN CN201410412076.5A patent/CN104230918B/zh not_active Expired - Fee Related
- 2008-02-01 JP JP2009547702A patent/JP5523110B2/ja not_active Expired - Fee Related
- 2008-02-01 US US12/518,548 patent/US8143402B2/en not_active Expired - Fee Related
- 2008-02-01 RU RU2009132660/04A patent/RU2533830C2/ru not_active IP Right Cessation
- 2008-02-01 CN CN201510303203.2A patent/CN105037347B/zh not_active Expired - Fee Related
- 2008-02-01 KR KR1020097015553A patent/KR101580226B1/ko not_active IP Right Cessation
- 2008-02-01 BR BRPI0806945-0A2A patent/BRPI0806945A2/pt not_active Application Discontinuation
- 2008-02-01 CL CL200800321A patent/CL2008000321A1/es unknown
- 2008-02-01 SI SI200831337T patent/SI2118098T1/sl unknown
- 2008-02-01 MX MX2009008275A patent/MX2009008275A/es active IP Right Grant
- 2008-02-01 CA CA2677170A patent/CA2677170C/fr not_active Expired - Fee Related
- 2008-02-01 NZ NZ577568A patent/NZ577568A/en not_active IP Right Cessation
-
2009
- 2009-06-07 IL IL199215A patent/IL199215A/en active IP Right Grant
- 2009-07-31 ZA ZA200905377A patent/ZA200905377B/xx unknown
-
2010
- 2010-02-03 HK HK10101152.0A patent/HK1137438A1/xx not_active IP Right Cessation
-
2014
- 2014-11-24 HR HRP20141137AT patent/HRP20141137T1/hr unknown
- 2014-12-11 CY CY20141101034T patent/CY1116339T1/el unknown
-
2015
- 2015-06-23 HK HK15105950.0A patent/HK1205125A1/xx unknown
-
2017
- 2017-06-19 AR ARP170101687A patent/AR108819A2/es unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20190128 |