HK1134094A1 - Processes for the preparation of 1,2,4-oxadiazole benzoic acids 124- - Google Patents

Processes for the preparation of 1,2,4-oxadiazole benzoic acids 124-

Info

Publication number
HK1134094A1
HK1134094A1 HK10102172.4A HK10102172A HK1134094A1 HK 1134094 A1 HK1134094 A1 HK 1134094A1 HK 10102172 A HK10102172 A HK 10102172A HK 1134094 A1 HK1134094 A1 HK 1134094A1
Authority
HK
Hong Kong
Prior art keywords
processes
preparation
benzoic acids
oxadiazole benzoic
oxadiazole
Prior art date
Application number
HK10102172.4A
Other languages
English (en)
Chinese (zh)
Inventor
尼爾‧
‧阿姆斯泰德
彼得‧承佑‧黃
希蒙‧派恩斯
穆英春
杰姆士‧
‧高杉
Original Assignee
醫療公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 醫療公司 filed Critical 醫療公司
Publication of HK1134094A1 publication Critical patent/HK1134094A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HK10102172.4A 2006-09-08 2010-03-01 Processes for the preparation of 1,2,4-oxadiazole benzoic acids 124- HK1134094A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US84359506P 2006-09-08 2006-09-08
PCT/US2007/019561 WO2008030570A1 (en) 2006-09-08 2007-09-06 Processes for the preparation of 1,2,4-oxadiazole benzoic acids

Publications (1)

Publication Number Publication Date
HK1134094A1 true HK1134094A1 (en) 2010-04-16

Family

ID=38935880

Family Applications (1)

Application Number Title Priority Date Filing Date
HK10102172.4A HK1134094A1 (en) 2006-09-08 2010-03-01 Processes for the preparation of 1,2,4-oxadiazole benzoic acids 124-

Country Status (25)

Country Link
US (2) US7678922B2 (xx)
EP (1) EP2059513B1 (xx)
JP (2) JP5955494B2 (xx)
KR (1) KR101466368B1 (xx)
CN (1) CN101535284B (xx)
AR (3) AR062715A1 (xx)
AU (1) AU2007292915B2 (xx)
BR (1) BRPI0716996B8 (xx)
CA (2) CA2842625C (xx)
CL (1) CL2007002606A1 (xx)
DK (1) DK2059513T3 (xx)
ES (1) ES2404348T3 (xx)
HK (1) HK1134094A1 (xx)
IL (1) IL197445A (xx)
MX (1) MX2009002439A (xx)
MY (1) MY148598A (xx)
NZ (2) NZ598012A (xx)
PE (2) PE20080771A1 (xx)
PL (1) PL2059513T3 (xx)
PT (1) PT2059513E (xx)
RU (1) RU2495030C2 (xx)
TW (1) TWI482761B (xx)
UA (1) UA99265C2 (xx)
WO (1) WO2008030570A1 (xx)
ZA (1) ZA200901782B (xx)

Families Citing this family (19)

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UA84420C2 (ru) 2003-04-11 2008-10-27 ПиТиСи ТЕРАПЬЮТИКС, ИНК. СОЕДИНЕНИЯ 1,2,4-ОКСАДИАЗОЛБЕНЗОЙНОЙ КИСЛОТЫ, ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ (ВАРИАНТЫ) И ПРИМЕНЕНИЕ СОЕДИНЕНИЙ ДЛЯ ЛЕЧЕНИЯ ЗАБОЛЕВАНИЯ, СВЯЗАННОГО С ПРЕЖДЕВРЕМЕННОЙ ТЕРМИНАЦИЕЙ ТРАНСЛЯЦИИ ИЛИ НОНСЕНС-ОБУСЛОВЛЕННЫМ УМЕНЬШЕНИЕМ мРНК
JP5800451B2 (ja) 2005-04-08 2015-10-28 ピーティーシー セラピューティクス，インコーポレーテッド ナンセンス突然変異抑制治療用の、経口的に活性な１，２，４−オキサジアゾール組成物
JP5367563B2 (ja) * 2006-03-30 2013-12-11 ピーティーシー セラピューティクス，インコーポレーテッド ナンセンス突然変異を有するｄｎａからの機能的タンパク質の産生のための方法及びそれと関連した障害の治療
CA2842625C (en) * 2006-09-08 2016-07-12 Ptc Therapeutics, Inc. Processes for the preparation of 1,2,4-oxadiazole benzoic acids
EP2068871B1 (en) 2006-09-25 2013-12-25 PTC Therapeutics, Inc. Hydroxylated 1,2,4-oxadiazole benzoic acid compounds, compositions thereof and the use for nonsense suppression
PL2559689T3 (pl) 2006-09-25 2018-04-30 Ptc Therapeutics, Inc. Sposób wytwarzania postaci krystalicznych kwasu 3-[5-(2-fluorofenylo)[1,2,4]oksadiazol-3-ilo]benzoesowego
PL2073805T3 (pl) 2006-10-12 2015-08-31 Ptc Therapeutics Inc Sposoby dawkowania 1,2,3-oksadiazolu aktywnego po podaniu doustnym w terapii supresyjnej mutacji nonsensownej
CN101714009A (zh) * 2009-05-14 2010-05-26 翁印嵩 集成通用电话功能的计算机
EP2668951B9 (en) 2011-01-25 2017-03-15 Viviabiotech, S.L. 1,2,4-oxadiazole derivatives as drugs modulating the glp-1 peptide receptor
MX352351B (es) 2012-07-02 2017-11-21 Monsanto Technology Llc Procesos para la preparacion de 1,2,4-oxadiazoles 3,5-disustituidos.
CA3174516A1 (en) 2014-03-06 2015-09-11 Ptc Therapeutics, Inc. Pharmaceutical compositions and salts of a 1,2,4-oxadiazole benzoic acid
CN105461650B (zh) * 2014-09-12 2018-04-13 杭州普晒医药科技有限公司 一种噁二唑化合物的溶剂化物及其制备方法
CN106316885B (zh) * 2015-07-03 2019-02-12 普济生物科技（台州）有限公司 一种3-[5-(2-氟苯基)-1,2,4-噁二唑-3-基]苯甲酸的制备方法
WO2017075312A1 (en) 2015-10-30 2017-05-04 Ptc Therapeutics, Inc. Methods for treating epilepsy
TW201808922A (zh) 2016-06-20 2018-03-16 台灣神隆股份有限公司 製備阿塔魯仁及其中間體的方法
US20220071965A1 (en) 2018-12-20 2022-03-10 Pfizer Inc. Pharmaceutical Compositions and Methods Comprising A Combination of a Benzoxazole Transthyretin Stabilizer and an Additional Therapeutic Agent
WO2022112919A1 (en) 2020-11-25 2022-06-02 Pfizer Inc. (aza)benzothiazolyl substituted pyrazole compounds
CN113045510B (zh) * 2021-03-31 2022-05-27 北京大学生命科学华东产业研究院 一种阿塔鲁伦的制备方法
CN114920667B (zh) * 2022-06-30 2024-06-21 湖南大学 一种阿塔鲁伦酯的电化学制备方法

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DE2801509A1 (de) * 1978-01-12 1979-07-19 Schering Ag 1,2,4-oxadiazolderivate, verfahren zur herstellung dieser verbindungen sowie diese enthaltende selektive herbizide mittel
DE3905242A1 (de) * 1989-02-21 1990-08-23 Basf Ag Verfahren zur herstellung von phenyloxdiazolylanilinen
NZ234760A (en) * 1989-08-18 1991-09-25 Sterling Drug Inc Antiviral oxazole compounds and compositions
DE4425794A1 (de) * 1994-07-21 1996-01-25 Basf Ag Nitrofarbstoffe
US6660753B2 (en) * 1999-08-19 2003-12-09 Nps Pharmaceuticals, Inc. Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists
CN1638776A (zh) * 2001-06-08 2005-07-13 西托维亚公司 取代的3－芳基－5－芳基－[1,2,4]－噁二唑和类似物
MY151199A (en) * 2001-11-02 2014-04-30 Rigel Pharmaceuticals Inc Substituted diphenyl heterocycles useful for treating hcv infection
TW200812986A (en) * 2002-08-09 2008-03-16 Nps Pharma Inc New compounds
GB0303503D0 (en) 2003-02-14 2003-03-19 Novartis Ag Organic compounds
UA84420C2 (ru) * 2003-04-11 2008-10-27 ПиТиСи ТЕРАПЬЮТИКС, ИНК. СОЕДИНЕНИЯ 1,2,4-ОКСАДИАЗОЛБЕНЗОЙНОЙ КИСЛОТЫ, ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ (ВАРИАНТЫ) И ПРИМЕНЕНИЕ СОЕДИНЕНИЙ ДЛЯ ЛЕЧЕНИЯ ЗАБОЛЕВАНИЯ, СВЯЗАННОГО С ПРЕЖДЕВРЕМЕННОЙ ТЕРМИНАЦИЕЙ ТРАНСЛЯЦИИ ИЛИ НОНСЕНС-ОБУСЛОВЛЕННЫМ УМЕНЬШЕНИЕМ мРНК
US20050075375A1 (en) * 2003-05-14 2005-04-07 Anadys Pharmaceuticals, Inc. Heterocyclic compounds for treating hepatitis C virus
JP5800451B2 (ja) 2005-04-08 2015-10-28 ピーティーシー セラピューティクス，インコーポレーテッド ナンセンス突然変異抑制治療用の、経口的に活性な１，２，４−オキサジアゾール組成物
CA2842625C (en) * 2006-09-08 2016-07-12 Ptc Therapeutics, Inc. Processes for the preparation of 1,2,4-oxadiazole benzoic acids

Also Published As

Publication number Publication date
CA2842625C (en) 2016-07-12
US20080139818A1 (en) 2008-06-12
US20100063297A1 (en) 2010-03-11
AR062715A1 (es) 2008-11-26
IL197445A0 (en) 2009-12-24
IL197445A (en) 2014-01-30
ZA200901782B (en) 2010-06-30
PE20120669A1 (es) 2012-06-01
MX2009002439A (es) 2009-03-27
EP2059513B1 (en) 2013-01-23
PL2059513T3 (pl) 2013-06-28
CN101535284B (zh) 2014-12-10
US7678922B2 (en) 2010-03-16
BRPI0716996A2 (pt) 2013-10-08
JP2010502715A (ja) 2010-01-28
DK2059513T3 (da) 2013-05-06
CA2662749A1 (en) 2008-03-13
TW200823180A (en) 2008-06-01
RU2009113019A (ru) 2010-10-20
WO2008030570A1 (en) 2008-03-13
JP5955494B2 (ja) 2016-07-20
US8367841B2 (en) 2013-02-05
CA2662749C (en) 2015-01-20
BRPI0716996B8 (pt) 2021-05-25
PT2059513E (pt) 2013-04-30
KR20090054464A (ko) 2009-05-29
NZ598012A (en) 2013-08-30
RU2495030C2 (ru) 2013-10-10
AR107474A2 (es) 2018-05-02
BRPI0716996B1 (pt) 2021-02-09
KR101466368B1 (ko) 2014-11-27
AR118922A2 (es) 2021-11-10
CN101535284A (zh) 2009-09-16
PE20080771A1 (es) 2008-06-13
EP2059513A1 (en) 2009-05-20
TWI482761B (zh) 2015-05-01
CA2842625A1 (en) 2008-03-13
UA99265C2 (ru) 2012-08-10
MY148598A (en) 2013-05-15
ES2404348T3 (es) 2013-05-27
JP2014193896A (ja) 2014-10-09
NZ575511A (en) 2012-02-24
CL2007002606A1 (es) 2008-04-18
AU2007292915A1 (en) 2008-03-13
AU2007292915B2 (en) 2012-07-26

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