HK1134072A1 - Orally bioavailable caffeic acid related anticancer drugs - Google Patents
Orally bioavailable caffeic acid related anticancer drugsInfo
- Publication number
- HK1134072A1 HK1134072A1 HK09111571.5A HK09111571A HK1134072A1 HK 1134072 A1 HK1134072 A1 HK 1134072A1 HK 09111571 A HK09111571 A HK 09111571A HK 1134072 A1 HK1134072 A1 HK 1134072A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- anticancer drugs
- caffeic acid
- orally bioavailable
- acid related
- related anticancer
- Prior art date
Links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
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- C07C233/24—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
- C07C233/29—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to an acyclic carbon atom of a carbon skeleton containing six-membered aromatic rings
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- C07C255/00—Carboxylic acid nitriles
- C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
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- C07C255/42—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being further bound to other hetero atoms
- C07C255/44—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being further bound to other hetero atoms at least one of the singly-bound nitrogen atoms being acylated
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
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- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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- C07D213/63—One oxygen atom
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- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
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Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US74410506P | 2006-03-31 | 2006-03-31 | |
PCT/US2007/065805 WO2007115269A2 (en) | 2006-03-31 | 2007-04-02 | Orally bioavailable caffeic acid related anticancer drugs |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1134072A1 true HK1134072A1 (en) | 2010-04-16 |
Family
ID=38462023
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK09111571.5A HK1134072A1 (en) | 2006-03-31 | 2009-12-10 | Orally bioavailable caffeic acid related anticancer drugs |
Country Status (13)
Country | Link |
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US (2) | US8779151B2 (pt) |
EP (2) | EP2514742B1 (pt) |
JP (2) | JP5654233B2 (pt) |
CN (1) | CN101454275B (pt) |
AU (1) | AU2007234455B2 (pt) |
BR (1) | BRPI0709916B8 (pt) |
CA (1) | CA2648003C (pt) |
ES (1) | ES2533383T3 (pt) |
HK (1) | HK1134072A1 (pt) |
MX (1) | MX2008012612A (pt) |
PL (1) | PL2514742T3 (pt) |
RU (1) | RU2456265C2 (pt) |
WO (1) | WO2007115269A2 (pt) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1701941B1 (en) * | 2003-12-11 | 2012-05-30 | Board of Regents, The University of Texas System | Compounds for treatment of cell proliferative diseases |
RU2456265C2 (ru) * | 2006-03-31 | 2012-07-20 | Дзе Борд Оф Риджентс Оф Дзе Юниверсити Оф Техас Систем | Биологически доступная для перорального применения кофейная кислота, относящаяся к противоопухолевым лекарственным средствам |
DK3050566T3 (en) * | 2007-09-10 | 2019-03-11 | Boston Biomedical Inc | NEW GROUP OF STAT3 PATHWAY INHIBITORS AND CANCERCELLE-PATHWAY INHIBITORS |
KR20110033922A (ko) * | 2008-07-08 | 2011-04-01 | 더 보드 오브 리전츠 오브 더 유니버시티 오브 텍사스 시스템 | 전사의 신호 변환자 및 활성제(stats)의 증식 및 활성화의 신규한 억제제 |
US8450337B2 (en) * | 2008-09-30 | 2013-05-28 | Moleculin, Llc | Methods of treating skin disorders with caffeic acid analogs |
MX2009008889A (es) * | 2009-08-20 | 2009-10-15 | Biokab S A De C V | Composiciones fitoceuticas para mascotas. |
CN102711765A (zh) * | 2009-11-16 | 2012-10-03 | 加利福尼亚大学董事会 | 激酶抑制剂 |
US20130129675A1 (en) | 2009-12-04 | 2013-05-23 | Board Of Regents, The University Of Texas System | Interferon therapies in combination with blockade of stat3 activation |
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BRPI0709916A2 (pt) | 2011-07-26 |
RU2008143237A (ru) | 2010-05-10 |
CN101454275A (zh) | 2009-06-10 |
EP2514742B1 (en) | 2014-12-31 |
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BRPI0709916B8 (pt) | 2021-05-25 |
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CN101454275B (zh) | 2014-07-23 |
AU2007234455B2 (en) | 2012-10-04 |
US20150094343A1 (en) | 2015-04-02 |
RU2456265C2 (ru) | 2012-07-20 |
JP5654233B2 (ja) | 2015-01-14 |
CA2648003A1 (en) | 2007-10-11 |
JP2009532387A (ja) | 2009-09-10 |
EP2514742A2 (en) | 2012-10-24 |
ES2533383T3 (es) | 2015-04-09 |
BRPI0709916B1 (pt) | 2020-09-29 |
CA2648003C (en) | 2014-07-08 |
MX2008012612A (es) | 2008-12-12 |
PL2514742T3 (pl) | 2015-07-31 |
AU2007234455A1 (en) | 2007-10-11 |
EP2007714A2 (en) | 2008-12-31 |
US8779151B2 (en) | 2014-07-15 |
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