HK1133442A1 - Influenza viruses having alterations in the hemaglutinin polypeptide - Google Patents
Influenza viruses having alterations in the hemaglutinin polypeptideInfo
- Publication number
- HK1133442A1 HK1133442A1 HK09111441.3A HK09111441A HK1133442A1 HK 1133442 A1 HK1133442 A1 HK 1133442A1 HK 09111441 A HK09111441 A HK 09111441A HK 1133442 A1 HK1133442 A1 HK 1133442A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- alterations
- influenza viruses
- hemaglutinin
- polypeptide
- hemaglutinin polypeptide
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/145—Orthomyxoviridae, e.g. influenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16211—Influenzavirus B, i.e. influenza B virus
- C12N2760/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16211—Influenzavirus B, i.e. influenza B virus
- C12N2760/16234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16211—Influenzavirus B, i.e. influenza B virus
- C12N2760/16241—Use of virus, viral particle or viral elements as a vector
- C12N2760/16243—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16211—Influenzavirus B, i.e. influenza B virus
- C12N2760/16261—Methods of inactivation or attenuation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US94460007P | 2007-06-18 | 2007-06-18 | |
PCT/US2008/067301 WO2008157583A1 (fr) | 2007-06-18 | 2008-06-18 | Virus b de la grippe présentant des modifications du polypeptide de l'hémagglutinine |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1133442A1 true HK1133442A1 (en) | 2010-03-26 |
Family
ID=40156672
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK09111441.3A HK1133442A1 (en) | 2007-06-18 | 2009-12-07 | Influenza viruses having alterations in the hemaglutinin polypeptide |
Country Status (8)
Country | Link |
---|---|
US (2) | US8673613B2 (fr) |
EP (2) | EP2069484B1 (fr) |
JP (1) | JP5666905B2 (fr) |
CN (1) | CN101715487A (fr) |
CA (1) | CA2690196A1 (fr) |
ES (1) | ES2523587T3 (fr) |
HK (1) | HK1133442A1 (fr) |
WO (1) | WO2008157583A1 (fr) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003091401A2 (fr) | 2002-04-26 | 2003-11-06 | Medimmune Vaccines, Inc. | Systeme multiplasmide de production de virus influenza |
US7465456B2 (en) | 2002-04-26 | 2008-12-16 | Medimmune, Llc | Multi plasmid system for the production of influenza virus |
ES2345492T3 (es) | 2003-12-23 | 2010-09-24 | Medimmune, Llc | Sistema multiplasmido para la produccion del virus de la gripe. |
WO2006062637A2 (fr) | 2004-11-03 | 2006-06-15 | Novartis Vaccines And Diagnostics Inc. | Vaccination antigrippale |
JP5666905B2 (ja) | 2007-06-18 | 2015-02-12 | メディミューン,エルエルシー | ヘマグルチニンポリペプチド中に変化を有するインフルエンザbウイルス |
US8506966B2 (en) | 2008-02-22 | 2013-08-13 | Novartis Ag | Adjuvanted influenza vaccines for pediatric use |
US20120027813A1 (en) * | 2008-02-22 | 2012-02-02 | Novartis Vaccines And Diagnostics Srl | Adjuvanted influenza vaccines for pediatric use |
US9884105B2 (en) | 2008-12-16 | 2018-02-06 | Ology Bioservices, Inc. | Production of viral vaccine |
DK2396032T3 (en) | 2009-02-10 | 2016-12-19 | Seqirus Uk Ltd | Influenza vaccines with reduced amounts of squalene |
JP2013507990A (ja) | 2009-10-26 | 2013-03-07 | ダブリュエーアールエフ−ウィスコンシン アラムナイ リサーチ ファウンデーション | ベロ細胞において増強された複製を有する高力価の組換えインフルエンザウイルス |
CN102864130A (zh) * | 2011-09-08 | 2013-01-09 | 中国农业科学院上海兽医研究所 | 高效表达ha蛋白的重组流感病毒及其制备方法和应用 |
NZ704188A (en) * | 2012-07-17 | 2016-04-29 | Merial Inc | Attenuated swine influenza vaccines and methods of making and use thereof |
US9950057B2 (en) | 2013-07-15 | 2018-04-24 | Wisconsin Alumni Research Foundation (Warf) | High titer recombinant influenza viruses with enhanced replication in MDCK or vero cells or eggs |
WO2015196150A2 (fr) | 2014-06-20 | 2015-12-23 | Wisconsin Alumni Research Foundation (Warf) | Mutations conférant une stabilité génétique à des gènes supplémentaires dans des virus de la grippe |
US10633422B2 (en) | 2015-06-01 | 2020-04-28 | Wisconsin Alumni Research Foundation (Warf) | Influenza virus replication by inhibiting microRNA lec7C binding to influenza viral cRNA and mRNA |
WO2017007839A1 (fr) | 2015-07-06 | 2017-01-12 | Wisconsin Alumni Research Foundation (Warf) | Réplication améliorée du virus de la grippe pour l'élaboration de vaccin |
CN109477074B (zh) * | 2016-02-19 | 2023-01-24 | 威斯康星旧生研究基金会 | 用于疫苗开发的改进的乙型流感病毒复制 |
JP2022527235A (ja) | 2019-01-23 | 2022-06-01 | 義裕 河岡 | インフルエンザウイルスにおける付加的遺伝子に遺伝的安定性を付与する突然変異 |
JP2022522112A (ja) | 2019-02-08 | 2022-04-14 | ウィスコンシン アルムニ リサーチ ファンデイション | ヒト化細胞系 |
US11390649B2 (en) | 2019-05-01 | 2022-07-19 | Wisconsin Alumni Research Foundation (Warf) | Influenza virus replication for vaccine development |
JP2022551805A (ja) | 2019-08-27 | 2022-12-14 | ウィスコンシン アルムニ リサーチ ファンデイション | 卵内複製のための安定化されたhaを持つ組換えインフルエンザウイルス |
CN116144612B (zh) * | 2022-12-08 | 2023-11-10 | 广州医科大学附属第一医院(广州呼吸中心) | 重组乙型流感病毒及其制备方法与应用 |
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ES2345492T3 (es) | 2003-12-23 | 2010-09-24 | Medimmune, Llc | Sistema multiplasmido para la produccion del virus de la gripe. |
EP2644696B1 (fr) | 2004-05-24 | 2015-07-15 | MedImmune, LLC | Méthode pour augmenter la réplication d'un virus de la grippe recombinant dans les oeufs |
ES2633471T3 (es) | 2004-10-06 | 2017-09-21 | Medimmune, Llc | Composiciones de vacuna contra la gripe estables a temperatura de refrigerador |
ES2382446T3 (es) | 2004-11-01 | 2012-06-08 | Eiken Kagaku Kabushiki Kaisha | Método de detección del virus de la gripe aviar H5 |
JP5666905B2 (ja) | 2007-06-18 | 2015-02-12 | メディミューン,エルエルシー | ヘマグルチニンポリペプチド中に変化を有するインフルエンザbウイルス |
JP2011512349A (ja) * | 2008-02-15 | 2011-04-21 | サン、ファーマ、アドバンスト、リサーチ、カンパニー、リミテッド | 経口放出制御錠剤 |
-
2008
- 2008-06-18 JP JP2010513371A patent/JP5666905B2/ja not_active Expired - Fee Related
- 2008-06-18 CA CA2690196A patent/CA2690196A1/fr not_active Abandoned
- 2008-06-18 EP EP08771329.3A patent/EP2069484B1/fr not_active Not-in-force
- 2008-06-18 ES ES08771329.3T patent/ES2523587T3/es active Active
- 2008-06-18 US US12/599,761 patent/US8673613B2/en not_active Expired - Fee Related
- 2008-06-18 EP EP13170051.0A patent/EP2674486A1/fr not_active Withdrawn
- 2008-06-18 WO PCT/US2008/067301 patent/WO2008157583A1/fr active Application Filing
- 2008-06-18 CN CN200880020720A patent/CN101715487A/zh active Pending
-
2009
- 2009-12-07 HK HK09111441.3A patent/HK1133442A1/xx not_active IP Right Cessation
-
2014
- 2014-01-22 US US14/161,430 patent/US9068986B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US20100322969A1 (en) | 2010-12-23 |
CN101715487A (zh) | 2010-05-26 |
EP2069484A1 (fr) | 2009-06-17 |
WO2008157583A1 (fr) | 2008-12-24 |
US20140199683A1 (en) | 2014-07-17 |
CA2690196A1 (fr) | 2008-12-24 |
JP5666905B2 (ja) | 2015-02-12 |
US9068986B2 (en) | 2015-06-30 |
ES2523587T3 (es) | 2014-11-27 |
AU2008265760A1 (en) | 2008-12-24 |
JP2010530248A (ja) | 2010-09-09 |
US8673613B2 (en) | 2014-03-18 |
EP2069484A4 (fr) | 2011-06-01 |
EP2674486A1 (fr) | 2013-12-18 |
EP2069484B1 (fr) | 2014-08-13 |
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Legal Events
Date | Code | Title | Description |
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PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20190614 Effective date: 20190618 |