HK1130723A1 - Solvent delivery system for liquid chromatography that maintains fluid integrity and pre-forms gradients - Google Patents

Solvent delivery system for liquid chromatography that maintains fluid integrity and pre-forms gradients

Info

Publication number
HK1130723A1
HK1130723A1 HK09108537.4A HK09108537A HK1130723A1 HK 1130723 A1 HK1130723 A1 HK 1130723A1 HK 09108537 A HK09108537 A HK 09108537A HK 1130723 A1 HK1130723 A1 HK 1130723A1
Authority
HK
Hong Kong
Prior art keywords
delivery system
liquid chromatography
solvent delivery
maintains fluid
fluid integrity
Prior art date
Application number
HK09108537.4A
Other languages
English (en)
Inventor
Steven J Ciavarini
Stanley P Pensak
Jeffrey W Finch
Keith Fadgen
Hongji Liu
Original Assignee
Waters Technologies Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Waters Technologies Corp filed Critical Waters Technologies Corp
Publication of HK1130723A1 publication Critical patent/HK1130723A1/xx

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N30/34—Control of physical parameters of the fluid carrier of fluid composition, e.g. gradient
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N30/32—Control of physical parameters of the fluid carrier of pressure or speed
    • G—PHYSICS
    • G05—CONTROLLING; REGULATING
    • G05D—SYSTEMS FOR CONTROLLING OR REGULATING NON-ELECTRIC VARIABLES
    • G05D11/00—Control of flow ratio
    • G05D11/02—Controlling ratio of two or more flows of fluid or fluent material
    • G05D11/13—Controlling ratio of two or more flows of fluid or fluent material characterised by the use of electric means
    • G05D11/131—Controlling ratio of two or more flows of fluid or fluent material characterised by the use of electric means by measuring the values related to the quantity of the individual components
    • G05D11/132—Controlling ratio of two or more flows of fluid or fluent material characterised by the use of electric means by measuring the values related to the quantity of the individual components by controlling the flow of the individual components
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N30/32—Control of physical parameters of the fluid carrier of pressure or speed
    • G01N2030/326—Control of physical parameters of the fluid carrier of pressure or speed pumps

Landscapes

  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Automation & Control Theory (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
HK09108537.4A 2006-03-17 2009-09-17 Solvent delivery system for liquid chromatography that maintains fluid integrity and pre-forms gradients HK1130723A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US78361006P 2006-03-17 2006-03-17
PCT/US2007/006679 WO2007109157A2 (en) 2006-03-17 2007-03-16 Solvent delivery system for liquid chromatography that maintains fluid integrity and pre-forms gradients

Publications (1)

Publication Number Publication Date
HK1130723A1 true HK1130723A1 (en) 2010-01-08

Family

ID=38522989

Family Applications (1)

Application Number Title Priority Date Filing Date
HK09108537.4A HK1130723A1 (en) 2006-03-17 2009-09-17 Solvent delivery system for liquid chromatography that maintains fluid integrity and pre-forms gradients

Country Status (6)

Country Link
US (3) US9103814B2 (ja)
EP (1) EP1996303B1 (ja)
JP (1) JP2009530615A (ja)
CN (1) CN101400418B (ja)
HK (1) HK1130723A1 (ja)
WO (1) WO2007109157A2 (ja)

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007092798A2 (en) 2006-02-08 2007-08-16 Waters Investments Limited Methods and apparatus for generating solvent gradients in liquid chromatography
GB2471956B (en) * 2006-02-08 2011-06-01 Waters Investments Ltd Control means for improved performance of chromatographic separations
JP4840015B2 (ja) * 2006-07-31 2011-12-21 株式会社島津製作所 液体クロマトグラフシステム
WO2010025777A1 (en) * 2008-09-08 2010-03-11 Agilent Technologies, Inc. Method transfer between fluidic devices considering deviations from ideal behavior
JP2012511723A (ja) * 2008-12-10 2012-05-24 オールテック・アソシエイツ・インコーポレーテッド クロマトグラフィーシステムのための溶媒供給システム、及び、その製造と使用の方法
EP2401502B1 (en) * 2009-02-27 2018-10-31 Waters Technologies Corporation Automated dilution for liquid chromatography
CN101614711B (zh) * 2009-04-03 2012-07-04 天津博纳艾杰尔科技有限公司 一种自动三级层析色谱仪
US20130135610A1 (en) * 2009-12-15 2013-05-30 Waters Technologies Corporation Device and methods for performing size exclusion chromatography
US20130014569A1 (en) 2009-12-18 2013-01-17 Waters Technologies Corporation Thermal-based flow sensing apparatus and method for high-performance liquid chromatography
JPWO2011090188A1 (ja) * 2010-01-25 2013-05-23 株式会社日立ハイテクノロジーズ 液体クロマトグラフ、および液体クロマトグラフ用送液装置
CN102362177B (zh) * 2010-01-26 2015-11-25 全技术联合公司 优化液相色谱系统中的梯度的方法
US8746270B2 (en) * 2010-02-10 2014-06-10 Brg Industries Incorporated Precision low flow rate fluid delivery system and methods for controlling same
JP5659969B2 (ja) * 2011-07-05 2015-01-28 株式会社島津製作所 低圧グラジエント装置
WO2013011818A1 (ja) * 2011-07-15 2013-01-24 株式会社島津製作所 液体クロマトグラフ用制御装置及びプログラム
EP2809414B1 (en) * 2012-02-01 2021-09-15 Waters Technologies Corporation System and method for managing fluidic connections to microfluidic devices
GB2553727B (en) * 2012-05-15 2018-12-05 Waters Technologies Corp Chromatographic materials
JP5861569B2 (ja) * 2012-06-21 2016-02-16 株式会社島津製作所 移動相送液装置及び液体クロマトグラフ
EP2888584B1 (en) * 2012-08-24 2018-02-28 GE Healthcare Bio-Sciences AB System and method for controlling a liquid chromatography system
US9086426B2 (en) 2012-09-12 2015-07-21 Dionex Corporation Multi-component eluent generating system and method
US9945820B2 (en) * 2012-11-30 2018-04-17 Agilent Technologies, Inc. Mixer bypass sample injection for liquid chromatography
JP6207872B2 (ja) * 2013-04-18 2017-10-04 株式会社日立ハイテクノロジーズ 液体クロマトグラフ装置および液体クロマトグラフ分析方法
JP2014215125A (ja) * 2013-04-24 2014-11-17 株式会社日立ハイテクノロジーズ 高圧力定流量ポンプ及び高圧力定流量送液方法
DE102013212540A1 (de) 2013-06-27 2014-12-31 Agilent Technologies Inc. Konditionieren eines nachfolgenden Probenpakets in einer Probentrennstufe während Prozessierens eines vorangehenden Probenpakets in einer Probenweiterverarbeitungsstufe
GB2524147B (en) * 2014-02-06 2016-02-10 Waters Technologies Corp Method for high pressure gradient chromatography using pump stroke control
WO2015123309A1 (en) * 2014-02-11 2015-08-20 Alltech Associates, Inc. Apparatus and methods for controlling pressure limits and flow rates in a chromatographic system
JP6331484B2 (ja) * 2014-03-04 2018-05-30 株式会社島津製作所 液体クロマトグラフ制御装置及び液体クロマトグラフ制御方法
EP3148664B1 (en) * 2014-05-29 2019-11-13 Agilent Technologies, Inc. Apparatus and method for introducing a sample into a separation unit of a chromatography system
CN104784990B (zh) * 2015-04-24 2017-07-11 中国能源建设集团广东省电力设计研究院有限公司 反冲洗装置的调度方法和系统
EP3093335A1 (de) * 2015-05-13 2016-11-16 Bayer Technology Services GmbH Prozessleitsystem zur regelung und steuerung einer modular aufgebauten anlage zur produktion von biopharmazeutischen und biologischen makromolekularen produkten
US9683511B2 (en) * 2015-05-14 2017-06-20 Ford Global Technologies, Llc Method and system for supplying fuel to an engine
CN106290675B (zh) * 2015-05-22 2020-03-31 达耐科学有限公司 谱峰终点调整方法及具有谱峰终点调整功能的色谱工作站
WO2017066630A1 (en) * 2015-10-16 2017-04-20 Lonza Ltd. System and method for regulating cell culture based production of biologics
US11275062B2 (en) * 2016-05-30 2022-03-15 Agilent Technologies, Inc Sample injection with fluidic connection between fluid drive unit and sample accommodation volume
JP6696578B2 (ja) * 2016-09-26 2020-05-20 株式会社島津製作所 切替バルブ、バイナリポンプ及びそのバイナリポンプを備えた液体クロマトグラフ
WO2018059639A1 (en) * 2016-09-28 2018-04-05 Evosep Aps Chromatographic analysis with low pressure dual gradient refocusing
DE102016121512A1 (de) * 2016-11-10 2018-05-17 Dionex Softron Gmbh System, Verfahren und Verwendung der Flüssigkeitschromatografie
WO2018128836A1 (en) * 2017-01-06 2018-07-12 Waters Technologies Corporation Modifier stream elution of trap column for multidimensional compressible fluid-based chromatography
CN106824006B (zh) * 2017-02-16 2018-09-04 中国科学院半导体研究所 一种防止交叉污染的多试剂顺序进液装置
CN107121504B (zh) * 2017-04-12 2019-08-20 岛津企业管理（中国）有限公司 多功能加温加压萃取-捕集-色谱分离在线联用设备
CN208060444U (zh) * 2017-06-14 2018-11-06 中国科学院过程工程研究所 一种可移动的具有双梯度调节功能的流动相控制系统
DE102017115242A1 (de) * 2017-07-07 2019-01-10 Dionex Softron Gmbh Pumpenbetriebsverfahren, Verwendung des Verfahrens bei HPLC, Pumpe, Pumpensystem und HPLC-System
US10976289B2 (en) * 2017-08-30 2021-04-13 Agilent Technologies, Inc. Corrected flow reporting under dynamic conditions by system modeling
WO2019067637A1 (en) * 2017-09-26 2019-04-04 Waters Technologies Corporation HIGH-PURITY CHROMATOGRAPHIC MATERIALS COMPRISING AN IONIZABLE MODIFIER FOR RETENTION OF ACID ANALYTES
CN108037233B (zh) * 2017-12-28 2024-05-03 大连博迈科技发展有限公司 基于同一检测器的全在线检测的多维液相色谱分离系统
US11879877B2 (en) * 2018-03-16 2024-01-23 Shimadzu Corporation Binary pump and liquid chromatograph provided with same
WO2019229673A1 (en) * 2018-05-30 2019-12-05 Waters Technologies Corporation System and method for controlling fluid flow within a chromatography system
US20220003722A1 (en) * 2018-10-15 2022-01-06 Shimadzu Corporation Chromatographic control device, chromatographic system, chromatographic control method and chromatographic control program
US11709085B2 (en) * 2019-08-21 2023-07-25 Waters Technologies Corporation Method for determining a dwell volume of a chromatographic system
CN115151816A (zh) 2019-11-27 2022-10-04 沃特世科技公司 梯度比例阀
CN111538959B (zh) * 2020-04-22 2023-09-01 常州三泰科技有限公司 基于机器学习技术的液相色谱分离仪的梯度推荐方法
GB202006310D0 (en) * 2020-04-29 2020-06-10 Puridify Ltd Preparative chromatography system and method for chromatography separations
CN115552237A (zh) * 2020-05-07 2022-12-30 沃特世科技公司 多维液相色谱系统
US20230184723A1 (en) * 2020-06-09 2023-06-15 Shimadzu Corporation Liquid chromatography analysis system
US20220168668A1 (en) * 2020-11-30 2022-06-02 PAK Biosolutions Inc. End-to-End Continuous Purification System
US20240175849A1 (en) * 2021-03-12 2024-05-30 Dh Technologies Development Pte. Ltd. Flow Module Selector
US12013382B2 (en) * 2022-06-17 2024-06-18 Trajan Scientific Australia Pty Ltd Compact and modular capillary liquid chromatography system
WO2024086615A1 (en) * 2022-10-18 2024-04-25 Equilibar, Llc Pumpless system for gradient buffer production

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1441462A (en) * 1973-02-14 1976-06-30 Univ Edinburgh University Cour Method and apapratus for liquid chromotography
NL7600264A (nl) * 1975-02-14 1976-08-17 Foxboro Co Inrichting voor het verwarmen en op constante temperatuur houden van een bepaald toestel.
US4917575A (en) * 1986-05-02 1990-04-17 The Dow Chemical Company Liquid chromatographic pump
US4767279A (en) * 1987-06-02 1988-08-30 Millipore Corporation Fluid composition and volumetric delivery control
US5240603A (en) * 1990-03-02 1993-08-31 Hewlett-Packard Company Decoupled flow and pressure setpoints in an extraction instrument using compressible fluids
DE69124556T2 (de) * 1990-09-11 1997-09-11 Prince Technologies B V Verfahren und Vorrichtung zur Einführung mindestens eines Flüssigkeitsvolumens in eine Röhre, insbesondere für kapillare Elektrophoresesysteme und Verfahren und Vorrichtung zur Trennung und/oder Analyse eines fluiden Materials
ATE178975T1 (de) * 1992-10-28 1999-04-15 Flux Instr Ag Hochdruckpumpe zur flüssigkeits-feindosierung
US6299767B1 (en) 1999-10-29 2001-10-09 Waters Investments Limited High pressure capillary liquid chromatography solvent delivery system
JP2002071657A (ja) 2000-08-29 2002-03-12 Jasco Corp グラジェント液体クロマトグラム測定装置および測定方法
US6858435B2 (en) 2000-10-03 2005-02-22 Dionex Corporation Method and system for peak parking in liquid chromatography-mass spectrometer (LC-MS) analysis
US6743356B1 (en) * 2000-10-27 2004-06-01 Johnson & Johnson High throughput high performance chromatography system
US20020187557A1 (en) * 2001-06-07 2002-12-12 Hobbs Steven E. Systems and methods for introducing samples into microfluidic devices
US7465382B2 (en) * 2001-06-13 2008-12-16 Eksigent Technologies Llc Precision flow control system
JP3865119B2 (ja) * 2001-06-29 2007-01-10 株式会社島津製作所 移動相グラジエント装置及びそれを用いた高速液体クロマトグラフ
JP2003185646A (ja) * 2001-12-13 2003-07-03 Moore Kk 高圧ステップワイズグラジエント送液システム
CN100528363C (zh) * 2002-02-13 2009-08-19 安捷伦科技有限公司 微流体分离柱装置及其制备方法
US6958119B2 (en) * 2002-02-26 2005-10-25 Agilent Technologies, Inc. Mobile phase gradient generation microfluidic device
US6780315B2 (en) * 2002-12-09 2004-08-24 Waters Investments Limited Backflow prevention for high pressure gradient systems
JP3823092B2 (ja) * 2003-03-11 2006-09-20 株式会社日立ハイテクノロジーズ 分離分析装置
JP3898688B2 (ja) * 2003-11-07 2007-03-28 株式会社日立ハイテクノロジーズ グラジエント送液装置
US7186336B2 (en) * 2003-11-26 2007-03-06 Waters Investments Limited Flow sensing apparatus
JP4959565B2 (ja) * 2004-05-21 2012-06-27 ウオーターズ・テクノロジーズ・コーポレイシヨン 低流量動作を可能にするためのｈｐｌｃ定流量ポンプの閉ループ流量制御
US7144502B2 (en) * 2004-06-04 2006-12-05 Johnson & Johnson Chromatography system with gradient storage and method for operating the same
US7670480B2 (en) * 2005-03-31 2010-03-02 Agilent Technologies, Inc. Solvent supply with correction of piston movement

Also Published As

Publication number Publication date
US20150346168A1 (en) 2015-12-03
US9103814B2 (en) 2015-08-11
JP2009530615A (ja) 2009-08-27
US20090205409A1 (en) 2009-08-20
WO2007109157A2 (en) 2007-09-27
CN101400418A (zh) 2009-04-01
US20210123891A1 (en) 2021-04-29
EP1996303A2 (en) 2008-12-03
EP1996303B1 (en) 2018-05-02
EP1996303A4 (en) 2011-09-28
CN101400418B (zh) 2012-11-14
WO2007109157A3 (en) 2008-03-20

Similar Documents

Publication Publication Date Title
HK1130723A1 (en) Solvent delivery system for liquid chromatography that maintains fluid integrity and pre-forms gradients
HK1247873A1 (zh) 用於注射系統的流體加壓單元的設備和方法
EP2061715A4 (en) LIQUID DISPENSER SYSTEM FOR DISPENSING LIQUID AROMAS
HK1148333A1 (zh) 用於液體燃料調節的方法和系統
EP2136897A4 (en) SYSTEMS AND METHOD FOR LIQUID SEPARATION
EP1932556A4 (en) MEDICAL LIQUID INJECTION SYSTEM
GB2447344B (en) Packing system and method for chromatography columns
HK1126748A1 (en) Gas injection system for liquid
EP2336764A4 (en) LIQUID CHROMATOGRAPH
PL1896120T3 (pl) System dostarczania kontrastowego płynu
EP1984278A4 (en) FLUID SUPPLY SYSTEM
EP2376208A4 (en) CHROMATOGRAPHY SYSTEMS AND SYSTEM COMPONENTS
EP2091818A4 (en) FLUID HANDLING SYSTEM
EP2188002A4 (en) FLUID HANDLING SYSTEM
EP2017615A4 (en) DEGASTER AND CHROMATOGRAPH IN ASSOCIATED LIQUID PHASE
EP2001787A4 (en) LIQUID DISPENSER SYSTEM
EP2049216A4 (en) METHOD AND DEVICE FOR PERVAPORATION CONTROL IN CHROMATOGRAPHIC SYSTEMS
BRPI0716484A2 (pt) Método para injeção de líquido e recipiente de líquido
AP2009005067A0 (en) Method for liquid control in multiphase fluid pipelines
EP1987446A4 (en) METHOD AND SYSTEM FOR INTEGRATION OF CALCULATION AND PRESENTATION TECHNOLOGIES
EP1988392A4 (en) LIQUID PHASE CHROMATOGRAPH
GB0618361D0 (en) Liquid leakage detection system
EP2024185A4 (en) SYSTEM AND METHOD FOR EXTRACTING LIQUID DROPS
ZA201002653B (en) Method,system and apparatus for housing and dispensing liquid
IL200236A0 (en) Methods and systems for pumping fluids

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20210314