HK1130496A1 - 3'-ethynylcytidine derivative 3'- - Google Patents

3'-ethynylcytidine derivative 3'-

Info

Publication number
HK1130496A1
HK1130496A1 HK09108626.6A HK09108626A HK1130496A1 HK 1130496 A1 HK1130496 A1 HK 1130496A1 HK 09108626 A HK09108626 A HK 09108626A HK 1130496 A1 HK1130496 A1 HK 1130496A1
Authority
HK
Hong Kong
Prior art keywords
substituted
group
hydrogen atom
represented
ethynylcytidine derivative
Prior art date
Application number
HK09108626.6A
Other languages
English (en)
Inventor
Motoaki Tanaka
Masakazu Fukushima
Original Assignee
Taiho Pharmaceutical Co Ltd
Takuma Sasaki
Matsuda Akira
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taiho Pharmaceutical Co Ltd, Takuma Sasaki, Matsuda Akira filed Critical Taiho Pharmaceutical Co Ltd
Publication of HK1130496A1 publication Critical patent/HK1130496A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H23/00—Compounds containing boron, silicon, or a metal, e.g. chelates, vitamin B12
HK09108626.6A 2006-07-24 2009-09-21 3'-ethynylcytidine derivative 3'- HK1130496A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2006200587 2006-07-24
PCT/JP2007/000787 WO2008012945A1 (fr) 2006-07-24 2007-07-23 Dérivé de 3'-éthynylcytidine

Publications (1)

Publication Number Publication Date
HK1130496A1 true HK1130496A1 (en) 2009-12-31

Family

ID=38981261

Family Applications (1)

Application Number Title Priority Date Filing Date
HK09108626.6A HK1130496A1 (en) 2006-07-24 2009-09-21 3'-ethynylcytidine derivative 3'-

Country Status (15)

Country Link
US (1) US8058261B2 (xx)
EP (1) EP2045258B1 (xx)
JP (1) JP4989649B2 (xx)
KR (1) KR101426101B1 (xx)
CN (1) CN101490076B (xx)
AT (1) ATE525386T1 (xx)
AU (1) AU2007278000B2 (xx)
BR (1) BRPI0714705A2 (xx)
CA (1) CA2658917C (xx)
HK (1) HK1130496A1 (xx)
MX (1) MX2009001003A (xx)
NZ (1) NZ574362A (xx)
RU (1) RU2441876C2 (xx)
TW (1) TWI449528B (xx)
WO (1) WO2008012945A1 (xx)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102219817A (zh) * 2011-04-12 2011-10-19 连云港杰瑞药业有限公司 活性偶联剂用于氟化嘧啶化合物烷氧羰酰化的方法
SG11201608538UA (en) * 2014-04-29 2016-11-29 Biosearch Technologies Inc Compounds compositions and methods including thermally labile moieties
WO2018230479A1 (ja) * 2017-06-13 2018-12-20 大原薬品工業株式会社 ヌクレオシド系抗がん剤又は抗ウィルス剤の５'位シリルエーテル誘導体
CN115536710B (zh) * 2022-10-18 2024-04-16 南京工业大学 一种高品质胞苷硫酸盐晶体的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL77133A (en) 1984-12-04 1991-01-31 Lilly Co Eli Antineoplastic pharmaceutical compositions containing pentofuranoside derivatives,some new such compounds and their preparation
ZA859008B (en) * 1984-12-04 1987-07-29 Lilly Co Eli The treatment of tumors in mammals
RU2130029C1 (ru) * 1994-12-13 1999-05-10 Тайхо Фармасьютикал Ко., Лтд. 3'-замещенные производные нуклеозида, способ их получения (варианты), лекарственное средство, способ лечения и профилактики
JP3792005B2 (ja) 1997-04-24 2006-06-28 彰 松田 ２−デオキシ−３−エチニル−β−Ｄ−リボフラノシル誘導体

Also Published As

Publication number Publication date
CA2658917C (en) 2014-10-21
TWI449528B (zh) 2014-08-21
RU2441876C2 (ru) 2012-02-10
MX2009001003A (es) 2009-02-06
EP2045258A1 (en) 2009-04-08
BRPI0714705A2 (pt) 2013-05-14
CN101490076B (zh) 2012-05-30
ATE525386T1 (de) 2011-10-15
TW200817014A (en) 2008-04-16
US20090306008A1 (en) 2009-12-10
KR101426101B1 (ko) 2014-08-13
CA2658917A1 (en) 2008-01-31
NZ574362A (en) 2010-10-29
AU2007278000B2 (en) 2011-12-15
US8058261B2 (en) 2011-11-15
EP2045258A4 (en) 2010-10-06
JP4989649B2 (ja) 2012-08-01
CN101490076A (zh) 2009-07-22
KR20090033875A (ko) 2009-04-06
EP2045258B1 (en) 2011-09-21
RU2009106034A (ru) 2010-08-27
AU2007278000A1 (en) 2008-01-31
WO2008012945A1 (fr) 2008-01-31
JPWO2008012945A1 (ja) 2009-12-17

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20160723