HK1122730A1 - Quinoline derivatives as antibacterial agents - Google Patents

Quinoline derivatives as antibacterial agents

Info

Publication number
HK1122730A1
HK1122730A1 HK08113967.4A HK08113967A HK1122730A1 HK 1122730 A1 HK1122730 A1 HK 1122730A1 HK 08113967 A HK08113967 A HK 08113967A HK 1122730 A1 HK1122730 A1 HK 1122730A1
Authority
HK
Hong Kong
Prior art keywords
antibacterial agents
quinoline derivatives
quinoline
derivatives
antibacterial
Prior art date
Application number
HK08113967.4A
Other languages
English (en)
Inventor
Koenraad Jozef Lodewijk Marcel Andries
Anil Koul
Jerome Emile Georges Guillemont
David Francis Alain Lancois
Magali Madeleine Simone Motte
Ismet Dorange
Leo Jacobus Jozef Backx
Lieven Meerpoel
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34940244&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1122730(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of HK1122730A1 publication Critical patent/HK1122730A1/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/04Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms
    • C07D215/06Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms having only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/22Oxygen atoms attached in position 2 or 4
    • C07D215/227Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HK08113967.4A 2005-06-28 2008-12-24 Quinoline derivatives as antibacterial agents HK1122730A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05105762 2005-06-28
PCT/EP2006/063553 WO2007000435A1 (en) 2005-06-28 2006-06-26 Quinoline derivatives as antibacterial agents

Publications (1)

Publication Number Publication Date
HK1122730A1 true HK1122730A1 (en) 2009-05-29

Family

ID=34940244

Family Applications (1)

Application Number Title Priority Date Filing Date
HK08113967.4A HK1122730A1 (en) 2005-06-28 2008-12-24 Quinoline derivatives as antibacterial agents

Country Status (32)

Country Link
US (1) US8841321B2 (no)
EP (1) EP1898914B1 (no)
JP (1) JP5193858B2 (no)
KR (1) KR101329585B1 (no)
CN (1) CN101247811B (no)
AP (1) AP2386A (no)
AR (1) AR054626A1 (no)
AU (1) AU2006263883B2 (no)
BR (1) BRPI0612498A8 (no)
CA (1) CA2612619C (no)
CY (1) CY1113579T1 (no)
DK (1) DK1898914T3 (no)
EA (1) EA014423B1 (no)
ES (1) ES2393203T3 (no)
HK (1) HK1122730A1 (no)
HR (1) HRP20120912T1 (no)
IL (1) IL188393A0 (no)
JO (1) JO2752B1 (no)
ME (1) ME01484B (no)
MX (1) MX2008000081A (no)
MY (1) MY153291A (no)
NO (1) NO342701B1 (no)
NZ (1) NZ564379A (no)
PA (1) PA8683801A1 (no)
PL (1) PL1898914T3 (no)
PT (1) PT1898914E (no)
RS (1) RS52517B (no)
SI (1) SI1898914T1 (no)
TW (1) TWI387457B (no)
UA (1) UA92175C2 (no)
WO (1) WO2007000435A1 (no)
ZA (1) ZA200711165B (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JO2683B1 (en) * 2006-12-06 2013-03-03 جانسين فارماسوتيكا ان. في Quinoline antibacterial derivatives
JO2970B1 (en) 2006-12-06 2016-03-15 جانسين فارماسوتيكا ان. في Quinoline antibacterial derivatives
WO2013160431A1 (en) 2012-04-27 2013-10-31 Janssen Pharmaceutica Nv Antibacterial quinoline derivatives
DK2841425T3 (en) 2012-04-27 2016-06-27 Janssen Pharmaceutica Nv ANTIBACTERIAL QUINOLIN DERIVATIVES
EP3237383B1 (en) 2014-12-23 2019-12-04 Albemarle Corporation One-step process for the synthesis of alkylated metyrapone analogs
CN106928139B (zh) * 2017-05-08 2019-06-25 福建省微生物研究所 一种贝达喹啉杂质的合成方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19937116A1 (de) * 1999-08-06 2001-02-08 Bayer Ag Moxifloxacin Kochsalzformulierung
SI2301544T1 (sl) * 2002-07-25 2013-01-31 Janssen Pharmaceutica, N.V. Derivati kinolina kot vmesne spojine za mikobakterijske inhibitorje
ATE423117T1 (de) * 2003-09-22 2009-03-15 Janssen Pharmaceutica Nv Heterocyclische 7-aminoalkylidenylchinolone und - naphthyridone
MXPA06013888A (es) * 2004-05-28 2007-01-26 Janssen Pharmaceutica Nv Uso de derivados de quinolina sustituidos para el tratamiento de enfermedades micobacterianas resistentes a los farmacos.
EE05394B1 (et) * 2004-12-24 2011-04-15 Janssen Pharmaceutica N.V. Kinoliinihendid kasutamiseks latentse tuberkuloosi ravis
AP2547A (en) 2005-06-28 2012-12-26 Janssen Pharmaceutica Nv Quinoline derivatives as antibacterial agents

Also Published As

Publication number Publication date
KR101329585B1 (ko) 2013-11-15
PA8683801A1 (es) 2007-01-17
ME01484B (me) 2014-04-20
EP1898914B1 (en) 2012-08-15
AP2386A (en) 2012-03-23
TW200740437A (en) 2007-11-01
ES2393203T3 (es) 2012-12-19
JO2752B1 (en) 2014-03-15
BRPI0612498A8 (pt) 2018-01-02
RS52517B (en) 2013-04-30
EA014423B1 (ru) 2010-12-30
NO342701B1 (no) 2018-07-09
ZA200711165B (en) 2011-05-25
SI1898914T1 (sl) 2013-01-31
US8841321B2 (en) 2014-09-23
CY1113579T1 (el) 2016-06-22
JP5193858B2 (ja) 2013-05-08
UA92175C2 (ru) 2010-10-11
AR054626A1 (es) 2007-07-04
CN101247811B (zh) 2013-01-02
PL1898914T3 (pl) 2013-01-31
WO2007000435A1 (en) 2007-01-04
IL188393A0 (en) 2008-08-07
TWI387457B (zh) 2013-03-01
US20100048585A1 (en) 2010-02-25
NO20080501L (no) 2008-02-28
MX2008000081A (es) 2008-03-24
NZ564379A (en) 2010-11-26
CN101247811A (zh) 2008-08-20
EP1898914A1 (en) 2008-03-19
CA2612619A1 (en) 2007-01-04
BRPI0612498A2 (pt) 2010-11-23
KR20080021156A (ko) 2008-03-06
AU2006263883B2 (en) 2012-12-13
PT1898914E (pt) 2012-11-20
AU2006263883A1 (en) 2007-01-04
EA200800154A1 (ru) 2008-10-30
HRP20120912T1 (hr) 2012-12-31
CA2612619C (en) 2015-12-01
JP2008543964A (ja) 2008-12-04
DK1898914T3 (da) 2012-11-26
MY153291A (en) 2015-01-29

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20210625