HK1117524A1 - Process for the syntesis of 5-(methyl-1h-imidazol-1-yl)-3-(tri fluorome th yl)-benzeneamine - Google Patents

Process for the syntesis of 5-(methyl-1h-imidazol-1-yl)-3-(tri fluorome th yl)-benzeneamine

Info

Publication number
HK1117524A1
HK1117524A1 HK08108277.9A HK08108277A HK1117524A1 HK 1117524 A1 HK1117524 A1 HK 1117524A1 HK 08108277 A HK08108277 A HK 08108277A HK 1117524 A1 HK1117524 A1 HK 1117524A1
Authority
HK
Hong Kong
Prior art keywords
syntesis
benzeneamine
imidazol
methyl
tri fluorome
Prior art date
Application number
HK08108277.9A
Other languages
English (en)
Inventor
Joseph Mckenna
Wen-Chung Shieh
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of HK1117524A1 publication Critical patent/HK1117524A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Steroid Compounds (AREA)
HK08108277.9A 2005-06-09 2008-07-25 Process for the syntesis of 5-(methyl-1h-imidazol-1-yl)-3-(tri fluorome th yl)-benzeneamine HK1117524A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US68897705P 2005-06-09 2005-06-09
US70559005P 2005-08-04 2005-08-04
PCT/US2006/022155 WO2006135641A2 (en) 2005-06-09 2006-06-07 PROCESS FOR THE SYNTHESIS OF 5- (METHYL-lH-IMIDAZOL-l-YL) -3- (TRI FLUOROME TH YL) -BENZENEAMINE

Publications (1)

Publication Number Publication Date
HK1117524A1 true HK1117524A1 (en) 2009-01-16

Family

ID=37091153

Family Applications (1)

Application Number Title Priority Date Filing Date
HK08108277.9A HK1117524A1 (en) 2005-06-09 2008-07-25 Process for the syntesis of 5-(methyl-1h-imidazol-1-yl)-3-(tri fluorome th yl)-benzeneamine

Country Status (32)

Country Link
US (2) US8124763B2 (es)
EP (1) EP1924574B1 (es)
JP (1) JP5118024B2 (es)
KR (3) KR20120066067A (es)
AR (1) AR053890A1 (es)
AT (1) ATE487709T1 (es)
AU (1) AU2006258051B2 (es)
BR (1) BRPI0611663A2 (es)
CA (1) CA2610105C (es)
CY (1) CY1111428T1 (es)
DE (1) DE602006018156D1 (es)
DK (1) DK1924574T3 (es)
EC (1) ECSP077982A (es)
EG (1) EG25039A (es)
GT (1) GT200600217A (es)
HK (1) HK1117524A1 (es)
IL (1) IL187421A (es)
JO (1) JO2636B1 (es)
MA (1) MA29599B1 (es)
MX (1) MX2007015423A (es)
MY (1) MY147436A (es)
NO (1) NO340743B1 (es)
NZ (1) NZ563740A (es)
PE (1) PE20070015A1 (es)
PL (1) PL1924574T3 (es)
PT (1) PT1924574E (es)
RU (1) RU2444520C2 (es)
SA (1) SA06270147B1 (es)
SI (1) SI1924574T1 (es)
TN (1) TNSN07463A1 (es)
TW (1) TWI430999B (es)
WO (1) WO2006135641A2 (es)

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TW201022240A (en) 2008-11-05 2010-06-16 Teva Pharma Nilotinib HCl crystalline forms
WO2010060074A1 (en) * 2008-11-24 2010-05-27 Teva Pharmaceutical Industries Ltd. Preparation of nilotinib and intermediates thereof
US20110053968A1 (en) * 2009-06-09 2011-03-03 Auspex Pharmaceuticals, Inc. Aminopyrimidine inhibitors of tyrosine kinase
JO3634B1 (ar) 2009-11-17 2020-08-27 Novartis Ag طريقة لعلاج اضطرابات تكاثرية وحالات مرضية أخرى متوسطة بنشاط كيناز bcr-abl، c-kit، ddr1، ddr2، أو pdgf-r
EP2691539B1 (en) 2011-03-31 2018-04-25 The Procter and Gamble Company Methods for identifying and evaluating skin-active agents effective for treating dandruff
AR086913A1 (es) * 2011-06-14 2014-01-29 Novartis Ag 4-metil-3-[[4-(3-piridinil)-2-pirimidinil]-amino]-n-[5-(4-metil-1h-imidazol-1-il)-3-(trifluoro-metil)-fenil]-benzamida amorfa, forma de dosificacion que la contiene y metodo para prepararlas
GB2514285B (en) 2012-02-13 2018-07-18 Grindeks Jsc Intermediates for a novel process of preparing imatinib and related tyrosine kinase inhibitors
WO2013184908A2 (en) 2012-06-06 2013-12-12 The Procter & Gamble Company Systems and methods for identifying cosmetic agents for hair/scalp care compositions
WO2015092624A1 (en) 2013-12-16 2015-06-25 Ranbaxy Laboratories Limited Nilotinib mono-oxalate and its crystalline form
CN103694176B (zh) 2014-01-07 2015-02-18 苏州立新制药有限公司 尼洛替尼中间体的制备方法
EP3095782A1 (en) 2015-05-18 2016-11-23 Esteve Química, S.A. New method for preparing 3-(4-methyl-1h-imidazol-1-yl)-5-(trifluoromethyl)benzenamine
WO2019152977A2 (en) 2018-02-05 2019-08-08 Bio-Rad Laboratories, Inc. Chromatography resin having an anionic exchange-hydrophobic mixed mode ligand
CN116808044A (zh) 2018-06-15 2023-09-29 汉达癌症医药责任有限公司 激酶抑制剂的盐类及其组合物
JP2020007240A (ja) * 2018-07-04 2020-01-16 住友化学株式会社 ベンズアミド化合物の製造方法

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Also Published As

Publication number Publication date
NO340743B1 (no) 2017-06-12
KR101514593B1 (ko) 2015-04-22
TWI430999B (zh) 2014-03-21
ECSP077982A (es) 2008-01-23
WO2006135641A3 (en) 2007-03-29
JP5118024B2 (ja) 2013-01-16
DK1924574T3 (da) 2011-02-14
NO20080157L (no) 2008-01-09
TNSN07463A1 (en) 2009-03-17
IL187421A0 (en) 2008-02-09
PE20070015A1 (es) 2007-02-06
US8946416B2 (en) 2015-02-03
KR20120066067A (ko) 2012-06-21
KR20130118394A (ko) 2013-10-29
US20120116081A1 (en) 2012-05-10
MY147436A (en) 2012-12-14
EP1924574B1 (en) 2010-11-10
MX2007015423A (es) 2008-02-21
PT1924574E (pt) 2011-02-08
CY1111428T1 (el) 2015-08-05
KR101216249B1 (ko) 2012-12-28
TW200726756A (en) 2007-07-16
JO2636B1 (en) 2012-06-17
EG25039A (en) 2011-07-06
US8124763B2 (en) 2012-02-28
US20080188656A1 (en) 2008-08-07
BRPI0611663A2 (pt) 2010-09-28
NZ563740A (en) 2011-03-31
WO2006135641A2 (en) 2006-12-21
RU2007148231A (ru) 2009-07-20
JP2008545786A (ja) 2008-12-18
SI1924574T1 (sl) 2011-02-28
PL1924574T3 (pl) 2011-04-29
KR20080022093A (ko) 2008-03-10
CA2610105C (en) 2014-03-25
DE602006018156D1 (de) 2010-12-23
EP1924574A2 (en) 2008-05-28
GT200600217A (es) 2007-03-28
AR053890A1 (es) 2007-05-23
AU2006258051B2 (en) 2010-09-09
RU2444520C2 (ru) 2012-03-10
MA29599B1 (fr) 2008-07-01
SA06270147B1 (ar) 2009-12-22
ATE487709T1 (de) 2010-11-15
IL187421A (en) 2011-11-30
CA2610105A1 (en) 2006-12-21
AU2006258051A1 (en) 2006-12-21

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