HK1110602A1 - Compositions and methods of using angiopoietin-like protein - Google Patents
Compositions and methods of using angiopoietin-like proteinInfo
- Publication number
- HK1110602A1 HK1110602A1 HK08104828.2A HK08104828A HK1110602A1 HK 1110602 A1 HK1110602 A1 HK 1110602A1 HK 08104828 A HK08104828 A HK 08104828A HK 1110602 A1 HK1110602 A1 HK 1110602A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- angiopoietin
- protein
- compositions
- methods
- Prior art date
Links
- 102000006501 Angiopoietin-like Proteins Human genes 0.000 title 1
- 108010019425 Angiopoietin-like Proteins Proteins 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/515—Angiogenesic factors; Angiogenin
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- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
- A01K67/0276—Knock-out vertebrates
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- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1891—Angiogenesic factors; Angiogenin
-
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- C—CHEMISTRY; METALLURGY
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/07—Animals genetically altered by homologous recombination
- A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
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- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/105—Murine
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
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- A—HUMAN NECESSITIES
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- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Environmental Sciences (AREA)
- Vascular Medicine (AREA)
- Wood Science & Technology (AREA)
- Toxicology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Cell Biology (AREA)
- General Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Animal Husbandry (AREA)
- Biodiversity & Conservation Biology (AREA)
- Microbiology (AREA)
- Cardiology (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US58987504P | 2004-07-20 | 2004-07-20 | |
PCT/US2005/025650 WO2006014678A2 (fr) | 2004-07-20 | 2005-07-19 | Compositions et methodes d'utilisation de la proteine 4 analogue a l'angiopoietine |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1110602A1 true HK1110602A1 (en) | 2008-07-18 |
Family
ID=35787695
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK08104828.2A HK1110602A1 (en) | 2004-07-20 | 2008-05-02 | Compositions and methods of using angiopoietin-like protein |
Country Status (19)
Country | Link |
---|---|
US (3) | US7371384B2 (fr) |
EP (1) | EP1781698B1 (fr) |
JP (2) | JP5318412B2 (fr) |
KR (1) | KR20070061524A (fr) |
CN (1) | CN101080419B (fr) |
AU (1) | AU2005269758B2 (fr) |
BR (1) | BRPI0513477A (fr) |
CA (1) | CA2574791A1 (fr) |
DK (1) | DK1781698T3 (fr) |
HK (1) | HK1110602A1 (fr) |
HU (1) | HUE029170T2 (fr) |
IL (4) | IL180752A0 (fr) |
LT (1) | LT1781698T (fr) |
MX (1) | MX2007000783A (fr) |
NO (1) | NO342525B1 (fr) |
NZ (2) | NZ552957A (fr) |
RU (2) | RU2380411C2 (fr) |
WO (1) | WO2006014678A2 (fr) |
ZA (1) | ZA200701184B (fr) |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050123925A1 (en) | 2002-11-15 | 2005-06-09 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of tumor |
US8604185B2 (en) | 2004-07-20 | 2013-12-10 | Genentech, Inc. | Inhibitors of angiopoietin-like 4 protein, combinations, and their use |
EP2172482A1 (fr) * | 2004-07-20 | 2010-04-07 | Genentech, Inc. | Inhibiteurs de protéines de type angiopoiétine 4, combinaisons, et leur utilisation |
RU2380411C2 (ru) * | 2004-07-20 | 2010-01-27 | Дженентек, Инк. | Способ ингибирования пролиферации гепатоцитов, способ ингибирования клеточной адгезии гепатоцитов и способ ингибирования биологической активности angptl4 в гепатоцитах или предшественниках гепатоцитов |
JP5366406B2 (ja) | 2005-01-07 | 2013-12-11 | レキシコン ファーマシューティカルズ インコーポレーテッド | アンジオポエチン様タンパク質4(angptl4)に対するモノクローナル抗体 |
EP1919495A4 (fr) * | 2005-08-19 | 2010-03-10 | Univ St Louis | Procedes et compositions permettant de traiter la radiosensibilite gastro-intestinale chez un sujet |
AU2007233263A1 (en) * | 2006-02-17 | 2007-10-11 | Genentech, Inc. | Gene disruptons, compositions and methods relating thereto |
JP2010539245A (ja) | 2007-09-14 | 2010-12-16 | 日東電工株式会社 | 薬物担体 |
CA2741034C (fr) * | 2008-10-20 | 2021-06-22 | Liposcience, Inc. | Indices d'insulinoresistance a base de lipoproteine et procedes associes, systemes et programmes informatiques pour generer ceux-ci |
SG10201406420XA (en) | 2009-10-14 | 2014-11-27 | Univ Nanyang Tech | Antiproliferative agent |
CN106146591B (zh) * | 2010-01-08 | 2020-07-31 | Ionis制药公司 | 血管生成素样3表达的调节 |
WO2011089152A1 (fr) * | 2010-01-20 | 2011-07-28 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Méthodes et composition pharmaceutique pour la préservation de l'intégrité de la barrière cellulaire de l'endothélium vasculaire |
NO2575858T3 (fr) * | 2010-06-05 | 2018-05-19 | ||
US9139629B2 (en) | 2010-06-05 | 2015-09-22 | The Uab Research Foundation | Methods for treatment of nephrotic syndrome and related conditions |
US9475850B2 (en) * | 2010-06-05 | 2016-10-25 | The Uab Research Foundation | Methods for treatment of nephrotic syndrome and related conditions |
EP2661626B1 (fr) * | 2011-01-08 | 2016-06-01 | Astute Medical, Inc. | Procédés et compositions pour diagnostiquer et pronostiquer une lésion rénale et une insuffisance rénale |
CN102692496B (zh) * | 2011-03-21 | 2015-10-28 | 上海市肿瘤研究所 | Angptl4作为缺氧检测的标志物及其应用 |
CN102692500B (zh) * | 2011-03-21 | 2015-06-10 | 上海市肿瘤研究所 | Angptl4作为血清学检测肝癌转移的标志物及其应用 |
CN102242198A (zh) * | 2011-05-25 | 2011-11-16 | 信阳师范学院 | 通过angptl4基因多态性进行牛育种方法 |
RU2711799C2 (ru) * | 2011-06-21 | 2020-01-22 | Элнилэм Фармасьютикалз, Инк. | КОМПОЗИЦИИ иРНК ДЛЯ СХОДНОГО С АНГИОПОЭТИНОМ 3(ANGPTL3) БЕЛКА И СПОСОБЫ ИХ ПРИМЕНЕНИЯ |
RS61292B1 (sr) | 2011-07-01 | 2021-02-26 | Monsanto Technology Llc | Postupci i jedinjenja za selektivnu regulaciju ekspresije belančevina |
EP3399316A1 (fr) * | 2011-08-08 | 2018-11-07 | Nanyang Technological University | Angiopoïétine-like 4 et son utilisation pour moduler la porosité des cellules |
KR20140101397A (ko) | 2011-12-09 | 2014-08-19 | 메타볼릭 파마슈티칼즈 피티와이 엘티디 | 성장 호르몬 단편들의 사용 |
TWI641687B (zh) * | 2012-05-29 | 2018-11-21 | 美商再生元醫藥公司 | 生產細胞株增強子 |
EP2874708B1 (fr) * | 2012-07-19 | 2020-04-08 | Nanyang Technological University | Un fragment du polypeptide de type angiopoïétine 4 pour l'utilisation dans la cicatrisation d'une plaie |
AU2014233219B2 (en) * | 2013-03-15 | 2018-02-22 | Sumant S. CHUGH | Methods for treatment of nephrotic syndrome and related conditions |
SG10201801507RA (en) | 2013-05-01 | 2018-03-28 | Ionis Pharmaceuticals Inc | Compositions and methods for modulating hbv and ttr expression |
EP3021942A4 (fr) * | 2013-07-19 | 2017-04-19 | The Regents of The University of California | Le facteur épidermique des globules gras du lait régule l'absorption des acides gras |
KR102298476B1 (ko) | 2013-12-24 | 2021-09-03 | 아이오니스 파마수티컬즈, 인코포레이티드 | 안지오포이에틴-유사 3 발현의 조절 |
US20170042870A1 (en) * | 2014-02-17 | 2017-02-16 | The Brigham And Women's Hospital, Inc. | Targeted nanoparticle compositions and methods of their use to treat obesity |
SI3137605T1 (sl) | 2014-05-01 | 2021-02-26 | Ionis Pharmaceuticals, Inc. | Sestavki in metode za modulacijo ekspresije angiopoetin 3-podobnega |
MX2017001746A (es) * | 2014-08-07 | 2017-04-27 | Novartis Ag | Anticuerpos anti proteina similar a angiopoyetina 4 y metodos de uso. |
TW201613977A (en) | 2014-08-07 | 2016-04-16 | Novartis Ag | Angiopoetin-like 4 (ANGPTL4) antibodies and methods of use |
CN105021827B (zh) * | 2015-07-17 | 2016-09-28 | 北京大学第一医院 | 检测血清血管生成素样蛋白2含量的物质在制备检测肝脏炎症和纤维化程度产品中的应用 |
US10704057B2 (en) | 2015-07-22 | 2020-07-07 | Monsanto Technology Llc | Methods and compositions for selective regulation of protein expression |
MX2018005277A (es) | 2015-11-06 | 2018-08-01 | Ionis Pharmaceuticals Inc | Modular la expresion de apolipoproteina (a). |
WO2018002719A1 (fr) * | 2016-06-29 | 2018-01-04 | Crispr Therapeutics Ag | Compositions et méthodes pour l'édition génomique |
JP7577654B2 (ja) * | 2018-11-13 | 2024-11-05 | リピゴン ファーマスーティカルス アー・ベー | 脂肪酸代謝の調節に影響を与えるangptl4オリゴヌクレオチド |
CN115279402A (zh) * | 2019-11-06 | 2022-11-01 | 西北大学 | 对ve-ptp磷酸酶的抑制保护肾免于缺血-再灌注损伤 |
AU2020399633A1 (en) | 2019-12-09 | 2022-07-07 | Empirico Inc. | Oligonucleotides for treatment of Angiopoietin like 4 (ANGPTL4) related diseases |
Family Cites Families (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5227158A (en) | 1991-06-10 | 1993-07-13 | Genentech, Inc. | Method of stimulating hepatocyte proliferation by administration of hepatocyte growth factor and gamma-interferon |
WO1999066041A1 (fr) | 1998-06-16 | 1999-12-23 | Human Genome Sciences, Inc. | 94 proteines humaines secretees |
US20020137890A1 (en) | 1997-03-31 | 2002-09-26 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US6348350B1 (en) | 1997-09-19 | 2002-02-19 | Genentech, Inc. | Ligand homologues |
US20030207375A1 (en) | 1997-10-24 | 2003-11-06 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
WO1999032515A2 (fr) | 1997-12-19 | 1999-07-01 | Zymogenetics, Inc. | Homologue de l'angiopoietine, adn le codant et procede de production dudit homologue |
US20030099994A1 (en) | 1998-03-02 | 2003-05-29 | Millennium Pharamceuticals, Inc. | Novel FDRG protein and nucleic acid molecules and uses therefor |
JP2002516067A (ja) | 1998-03-02 | 2002-06-04 | ミレニアム・フアーマシユーチカルズ・インコーポレーテツド | 新規fdrgタンパク質および核酸分子、ならびにそのための用途 |
JP2000026767A (ja) | 1998-05-01 | 2000-01-25 | Daikin Ind Ltd | 熱硬化性粉体塗料組成物 |
AU4643699A (en) | 1998-06-24 | 2000-01-10 | Compugen Ltd. | Angiopoietin-like growth factor sequences |
WO2001057188A2 (fr) | 2000-02-03 | 2001-08-09 | Hyseq, Inc. | Nouveaux acides nucleiques et polypeptides |
WO2001053455A2 (fr) | 1999-12-23 | 2001-07-26 | Hyseq, Inc. | Nouveaux acides nucleiques et polypeptides associes |
JP2000308488A (ja) | 1999-02-23 | 2000-11-07 | Herikkusu Kenkyusho:Kk | 血管新生に関連するタンパク質および該タンパク質をコードする遺伝子 |
AU3391200A (en) | 1999-03-04 | 2000-09-21 | Corixa Corporation | Compositions and methods for breast cancer therapy and diagnosis |
PT1623989E (pt) | 1999-03-08 | 2007-09-25 | Genentech Inc | ''composições e métodos para o diagnóstico de tumores'' |
CA2370489A1 (fr) | 1999-04-09 | 2000-10-19 | Human Genome Sciences, Inc. | 49 proteines humaines secretees |
DE60041367D1 (de) | 1999-04-16 | 2009-02-26 | Genentech Inc | Vaskuläre Endothelzellen Wachstumsfaktor (VEGF) Varianten und dessen Verwendungen |
WO2001002429A2 (fr) | 1999-07-02 | 2001-01-11 | Bayer Aktiengesellschaft | Angiopoietine 6 et ses utilisations |
EP1210363A2 (fr) | 1999-07-16 | 2002-06-05 | Hyseq, Inc. | Nouveaux procedes et materiaux des angiopoietines |
US20030207348A1 (en) | 1999-07-20 | 2003-11-06 | Shimkets Richard A. | Polypeptides and polynucleotides encoding same |
EP1196576A2 (fr) | 1999-07-20 | 2002-04-17 | Curagen Corporation | Polypeptides secretes et polynucleotides correspondants |
AU2001233041A1 (en) | 2000-01-25 | 2001-08-07 | Hyseq, Inc. | Novel nucleic acids and polypeptides |
CN1315451A (zh) | 2000-03-29 | 2001-10-03 | 上海博德基因开发有限公司 | 一种新的多肽——人血管形成素类似因子45和编码这种多肽的多核苷酸 |
WO2001077151A2 (fr) | 2000-04-07 | 2001-10-18 | Millennium Pharmaceuticals, Inc. | Nouvelles molecules de proteines et d'acide nucleique fdrg et utilisation desdites molecules |
US6673545B2 (en) | 2000-07-28 | 2004-01-06 | Incyte Corporation | Prostate cancer markers |
CN1170850C (zh) | 2000-09-19 | 2004-10-13 | 上海市肿瘤研究所 | 人血管生成素样蛋白和编码序列及其用途 |
US20040249141A1 (en) | 2000-10-16 | 2004-12-09 | Audrey Goddard | Tie ligand homologues |
EP1506398A4 (fr) | 2001-03-27 | 2005-06-29 | Human Genome Sciences Inc | Proteines secretees humaines |
EP1403367A4 (fr) | 2001-06-08 | 2005-08-17 | Sankyo Co | Procede de test de medicament destine a traiter ou a prevenir des maladies telles que l'hyperlipemie |
WO2003010205A1 (fr) | 2001-07-26 | 2003-02-06 | Duke University Medical Center | Genes induits par hypoxie |
CA2459219A1 (fr) | 2001-09-17 | 2003-03-27 | Protein Design Labs, Inc. | Procedes de diagnostic du cancer, compositions et procedes de criblage de modulateurs du cancer |
US20050123925A1 (en) | 2002-11-15 | 2005-06-09 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of tumor |
US20040038230A1 (en) | 2001-11-05 | 2004-02-26 | Alsobrook John P. | Therapeutic polypeptides, nucleic acids encoding same, and methods of use |
EP1539985A4 (fr) | 2001-11-05 | 2006-06-28 | Curagen Corp | Polypeptides therapeutiques, acides nucleiques encodant ces polypeptides, et procedes d'utilisation |
CN101905024A (zh) | 2001-11-16 | 2010-12-08 | 杰南技术公司 | 含有血管生成素-样蛋白质3angptl3的组合物及其使用方法 |
AU2002359464A1 (en) | 2001-11-30 | 2003-06-17 | Genvec, Inc. | Angiopioetin related factors |
EP2277910A1 (fr) | 2001-12-21 | 2011-01-26 | Human Genome Sciences, Inc. | Protéines de fusion d'albumine |
JP5111729B2 (ja) | 2002-06-05 | 2013-01-09 | ジェネンテック, インコーポレイテッド | 肝成長及び肝保護のための組成物と方法 |
US20050239706A1 (en) | 2003-10-31 | 2005-10-27 | Washington University In St. Louis | Modulation of fiaf and the gastrointestinal microbiota as a means to control energy storage in a subject |
CA2499791A1 (fr) | 2004-03-30 | 2005-09-30 | F. Hoffmann-La Roche Ag | Angptl4/fiaf utilises comme marqueurs de modulation ppardelta |
EP2172482A1 (fr) | 2004-07-20 | 2010-04-07 | Genentech, Inc. | Inhibiteurs de protéines de type angiopoiétine 4, combinaisons, et leur utilisation |
RU2380411C2 (ru) * | 2004-07-20 | 2010-01-27 | Дженентек, Инк. | Способ ингибирования пролиферации гепатоцитов, способ ингибирования клеточной адгезии гепатоцитов и способ ингибирования биологической активности angptl4 в гепатоцитах или предшественниках гепатоцитов |
JP5366406B2 (ja) * | 2005-01-07 | 2013-12-11 | レキシコン ファーマシューティカルズ インコーポレーテッド | アンジオポエチン様タンパク質4(angptl4)に対するモノクローナル抗体 |
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