HK1102758A1 - 膠溶蛋白是用來治療傳染病 - Google Patents

膠溶蛋白是用來治療傳染病

Info

Publication number
HK1102758A1
HK1102758A1 HK07109233.1A HK07109233A HK1102758A1 HK 1102758 A1 HK1102758 A1 HK 1102758A1 HK 07109233 A HK07109233 A HK 07109233A HK 1102758 A1 HK1102758 A1 HK 1102758A1
Authority
HK
Hong Kong
Prior art keywords
gelsolin
treating infections
infections
treating
Prior art date
Application number
HK07109233.1A
Other languages
English (en)
Inventor
Thomas P Stossel
Po-Shun Lee
Original Assignee
Brigham & Womens Hospital Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Brigham & Womens Hospital Inc filed Critical Brigham & Womens Hospital Inc
Publication of HK1102758A1 publication Critical patent/HK1102758A1/zh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/085Staphylococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/002Protozoa antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/02Antidotes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • AIDS & HIV (AREA)
  • Pulmonology (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK07109233.1A 2004-05-12 2007-08-24 膠溶蛋白是用來治療傳染病 HK1102758A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US57023304P 2004-05-12 2004-05-12
PCT/US2005/016798 WO2005112970A2 (en) 2004-05-12 2005-05-12 Use of gelsolin to treat infections

Publications (1)

Publication Number Publication Date
HK1102758A1 true HK1102758A1 (zh) 2007-12-07

Family

ID=35428845

Family Applications (1)

Application Number Title Priority Date Filing Date
HK07109233.1A HK1102758A1 (zh) 2004-05-12 2007-08-24 膠溶蛋白是用來治療傳染病

Country Status (13)

Country Link
US (4) US10022424B2 (zh)
EP (2) EP2335722B1 (zh)
JP (4) JP5905183B2 (zh)
KR (2) KR101314461B1 (zh)
CN (1) CN1980694B (zh)
AU (1) AU2005244865A1 (zh)
CA (2) CA2860173C (zh)
DK (1) DK1755661T3 (zh)
ES (2) ES2464444T3 (zh)
HK (1) HK1102758A1 (zh)
PL (1) PL1755661T3 (zh)
PT (1) PT1755661E (zh)
WO (1) WO2005112970A2 (zh)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080113025A1 (en) * 1998-11-02 2008-05-15 Elan Pharma International Limited Compositions comprising nanoparticulate naproxen and controlled release hydrocodone
DK1126826T6 (en) * 1998-11-02 2019-06-24 Alkermes Pharma Ireland Ltd Multiparticulate modified release of methylphenidate
US6849605B1 (en) 1999-03-05 2005-02-01 The Trustees Of University Technology Corporation Inhibitors of serine protease activity, methods and compositions for treatment of viral infections
DK2520654T3 (en) 2003-08-26 2017-05-01 Univ Colorado Regents Inhibitors of serine protease activity and their use in methods and compositions for the treatment of bacterial infections
US9408891B2 (en) 2003-11-12 2016-08-09 The Trustees Of The University Of Pennsylvania Methods of using gelsolin to treat or prevent bacterial sepsis
CA2545718C (en) * 2003-11-12 2016-05-10 The Trustees Of The University Of Pennsylvania Methods of using gelsolin to treat or prevent bacterial sepsis
CA2860173C (en) 2004-05-12 2021-12-14 The Brigham And Women's Hospital, Inc. Determining plasma gelsolin level to predict risk of developing infection
KR101337045B1 (ko) 2005-02-16 2013-12-05 아나코르 파마슈티칼스 인코포레이티드 보론함유 소분자
US20090227518A1 (en) * 2005-12-02 2009-09-10 The Regents Of The University Of Colorado Compositions and methods for treating actin-mediated medical conditions
EP1976536A4 (en) 2005-12-30 2011-03-02 Anacor Pharmaceuticals Inc SMALL MOLECULES CONTAINING BORON
WO2007095638A2 (en) * 2006-02-16 2007-08-23 Anacor Pharmaceuticals, Inc. Boron-containing small molecules as anti-inflammatory agents
PT2002258T (pt) 2006-03-15 2017-12-18 The Brigham And Women`S Hospital Inc Utilização de gelsolina para o tratamento da esclerose múltipla e para o diagnóstico de doenças neurológicas
JP5322917B2 (ja) * 2006-03-15 2013-10-23 ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッド 炎症性疾患の診断および処置のためのゲルゾリンの使用
AU2013202205C1 (en) * 2006-03-15 2018-05-17 The Brigham And Women's Hospital, Inc. Use of Gelsolin to Diagnose and Treat Inflammatory Disease
JO3396B1 (ar) 2007-06-20 2019-10-20 Anacor Pharmaceuticals Inc جزيئات صغيرة تحتوي على البورون
ES2531827T3 (es) * 2008-01-25 2015-03-20 The General Hospital Corporation Usos terapéuticos de gelsolina en insuficiencia renal
US8039450B2 (en) 2008-03-06 2011-10-18 Anacor Pharmaceuticals, Inc. Boron-containing small molecules as anti-inflammatory agents
WO2009140309A2 (en) * 2008-05-12 2009-11-19 Anacor Pharmaceuticals, Inc. Boron-containing small molecules
US8461336B2 (en) 2008-09-04 2013-06-11 Anacor Pharmaceuticals, Inc. Boron-containing small molecules
WO2010027975A1 (en) * 2008-09-04 2010-03-11 Anacor Pharmaceuticals, Inc. Boron-containing small molecules
US9493489B2 (en) * 2008-10-15 2016-11-15 Anacor Pharmaceuticals, Inc. Boron-containing small molecules as anti-protozoal agents
CN102256494A (zh) * 2008-12-17 2011-11-23 阿纳科制药公司 (s)-3-氨甲基-7-(3-羟基-丙氧基)-3h-苯并[c][1,2]氧杂硼杂环戊-1-醇的多晶型物
AU2010281439A1 (en) * 2009-07-28 2012-03-15 Anacor Pharmaceuticals, Inc. Trisubstituted boron-containing molecules
WO2011019618A1 (en) * 2009-08-14 2011-02-17 Anacor Pharmaceuticals, Inc. Boron-containing small molecules as antiprotozoal agents
US20110207701A1 (en) * 2009-08-19 2011-08-25 Anacor Pharmaceuticals, Inc. Boron-containing small molecules as antiprotozoal agents
US20110124597A1 (en) * 2009-09-25 2011-05-26 Anacor Pharmaceuticals, Inc. Boron containing small molecules
WO2011049971A1 (en) 2009-10-20 2011-04-28 Anacor Pharmaceuticals, Inc. Boron-containing small molecules as antiprotozoal agents
WO2011060196A1 (en) * 2009-11-11 2011-05-19 Anacor Pharmaceuticals, Inc. Boron-containing small molecules
US8716478B2 (en) 2010-01-27 2014-05-06 Anacor Pharmaceuticals, Inc. Boron-containing small molecules
US8623911B2 (en) 2010-03-19 2014-01-07 Anacor Pharmaceuticals, Inc. Boron-containing small molecules as anti-protozoal agent
PL3251678T3 (pl) 2010-09-07 2022-01-10 Anacor Pharmaceuticals, Inc. Pochodne benzoksaborolu do leczenia zakażeń bakteryjnych
US20120316211A1 (en) * 2011-05-11 2012-12-13 The Board or Regents of the University of Texas System Diagnostic Methods for Assessing Risk of Chagas Disease and Heart Failure
CA2839917A1 (en) 2011-06-24 2012-12-27 The Regents Of The University Of Colorado, A Body Corporate Compositions, methods and uses for alpha-1 antitrypsin fusion molecules
WO2013106589A1 (en) 2012-01-10 2013-07-18 The Regents Of The University Of Colorado, A Body Corporate Compositions, methods and uses for alpha-1 antitrypsin fusion molecules
AU2014206087A1 (en) * 2013-01-14 2015-05-28 Wockhardt Limited Compositions and methods for treating bacterial infections
WO2016033187A1 (en) * 2014-08-26 2016-03-03 The Brigham And Women's Hospital, Inc. Use of gelsolin in the treatment and diagnosis of sickle cell disease
FR3036188B1 (fr) * 2015-05-12 2019-06-07 Biomerieux Prediction du risque de developper, pour des patients admis en service de reanimation, une infection disseminee
TW201718627A (zh) * 2015-06-11 2017-06-01 梅茲製藥有限兩合公司 重組梭菌神經毒素及其使用與形成方法、包括其之醫藥組合物及對應其之前驅物、編碼前驅物之核酸序列及其獲得方法與前驅物之形成方法、載體與包括核酸序列之重組宿主細胞
RU2743746C2 (ru) 2016-03-02 2021-02-25 Мерц Фарма Гмбх Энд Ко. Кгаа Композиция, содержащая ботулинический токсин
US11447506B2 (en) 2016-05-09 2022-09-20 Anacor Pharmaceuticals, Inc. Crystal forms of crisaborole in free form and preparation method and use thereof
WO2018233813A1 (en) 2017-06-20 2018-12-27 Merz Pharma Gmbh & Co. Kgaa NOVEL RECOMBINANT BOTULINUM TOXINS WITH INCREASED DURATION
US11155802B2 (en) 2017-07-06 2021-10-26 Merz Pharma Gmbh & Co. Kgaa Recombinant botulinum neurotoxins with increased duration of effect
IT201700083044A1 (it) * 2017-07-20 2019-01-20 Laura Stronati “uso della gelsolina come marcatore diagnostico e prognostico delle malattie infiammatorie intestinali”
CN111317739A (zh) * 2018-12-14 2020-06-23 复旦大学 依托红霉素在制备特异性抑制病毒感染的药物中的用途
WO2020257743A1 (en) * 2019-06-21 2020-12-24 Bioaegis Therapeutics Inc. Compositions and synergistic methods for treating infections

Family Cites Families (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US565659A (en) * 1896-08-11 Driving-gearing for cycles
US5071773A (en) 1986-10-24 1991-12-10 The Salk Institute For Biological Studies Hormone receptor-related bioassays
CA2016227A1 (en) 1989-05-18 1990-11-18 Xandra O. Breakefield Genetic diagnosis of torsion dystonia
US5464817A (en) 1990-04-11 1995-11-07 Brigham And Women's Hospital Method for reducing the viscosity of pathological mucoid airway contents in the respiratory tract comprising administering actin-binding compounds with or without DNASE I
DK0526544T3 (da) 1990-04-11 1999-06-21 Brigham & Womens Hospital Terapeutiske anvendelser af actinbindende forbindelser
CA2063593A1 (en) * 1990-05-04 1991-11-05 R. Blake Pepinsky Multimeric gelsolin fusion constructs
US5571511A (en) 1990-10-22 1996-11-05 The U.S. Government Broadly reactive opsonic antibodies that react with common staphylococcal antigens
CA2082951C (en) 1991-03-15 1999-12-21 Robert M. Platz Pulmonary administration of granulocyte colony stimulating factor
US5360350A (en) 1991-08-23 1994-11-01 The Whitaker Corporation Sealant compositions and sealed electrical connectors
CA2141600A1 (en) * 1992-08-03 1994-02-17 Richard U. Margolis Cloning, expression and uses for neurocan as a chondroitin sulfate proteoglycan
US5691160A (en) 1992-08-14 1997-11-25 Biogen, Inc. Effects of actin filaments of fibrin clot structure and lysis
JPH08506001A (ja) 1992-10-01 1996-07-02 ザ ゼネラル ホスピタル コーポレーション 腫瘍サプレッサー遺伝子の機能検査
US5830436A (en) * 1993-03-30 1998-11-03 Duke University Method of mucociliary clearance in cystic fibrosis patients using alkylaryl polyether alcohol polymers
US5593964A (en) * 1993-10-07 1997-01-14 The George Washington University Medical Center Method of treating septic shock by preventing actin polymerization
JP3914272B2 (ja) * 1993-12-28 2007-05-16 中外製薬株式会社 アドゼベリンをコードする遺伝子
CA2184385A1 (en) * 1994-03-11 1995-09-14 Philip Davies Composition for the treatment of lung disease
US5451569A (en) 1994-04-19 1995-09-19 Hong Kong University Of Science And Technology R & D Corporation Limited Pulmonary drug delivery system
US5846743A (en) 1995-02-22 1998-12-08 Brigham And Women's Hospital, Inc. Polyphoshoinositide binding peptides for intracellular drug delivery
EP0815134B1 (en) 1995-03-14 2002-06-05 Praecis Pharmaceuticals Incorporated Modulators of amyloid aggregation
US5804427A (en) 1995-05-19 1998-09-08 University Of Massachusetts Cytokine-, stress-, and oncoprotein-activated human protein kinase kinases
US5925529A (en) 1995-06-07 1999-07-20 The Regents Of The University Of California Method for discovery of peptide agonists
US5569588A (en) 1995-08-09 1996-10-29 The Regents Of The University Of California Methods for drug screening
US5750353A (en) 1995-12-11 1998-05-12 New England Medical Center Hospitals, Inc. Assay for non-peptide agonists to peptide hormone receptors
US6179489B1 (en) * 1997-04-04 2001-01-30 Texas Instruments Incorporated Devices, methods, systems and software products for coordination of computer main microprocessor and second microprocessor coupled thereto
WO1998004589A2 (en) * 1996-07-30 1998-02-05 Biogen, Inc. Production of recombinant plasma gelsolin containing a disulfide bond
DK0941108T3 (da) * 1996-12-04 2002-11-18 Renovo Ltd Sårheling og behandling af fibrose
AU7100898A (en) 1997-04-02 1998-10-22 Brigham And Women's Hospital Means of ascertaining an individual's risk profile for atherosclerotic disease
AU3395900A (en) * 1999-03-12 2000-10-04 Human Genome Sciences, Inc. Human lung cancer associated gene sequences and polypeptides
WO2001024828A2 (en) 1999-10-06 2001-04-12 Basf Aktiengesellschaft MODULATORS OF CYTOKINE MEDIATED SIGNALLING PATHWAYS AND INTEGRIN αVβ3 RECEPTOR ANTAGONISTS FOR COMBINATION THERAPY
US6671818B1 (en) * 1999-11-22 2003-12-30 Accenture Llp Problem isolation through translating and filtering events into a standard object format in a network based supply chain
US6802063B1 (en) * 2000-07-13 2004-10-05 International Business Machines Corporation 64-bit open firmware implementation and associated api
WO2002059604A2 (en) 2001-01-26 2002-08-01 Oxford Glycosciences (Uk) Ltd Diagnosis and treatment of multiple sclerosis
EP1372720A4 (en) 2001-03-02 2006-07-26 Medimmune Inc PREVENTING OR TREATING INFLAMMATORY OR AUTOIMMUNE DISORDERS BY ADMINISTERING ANTAGONISTS OF INTEGRIN ALPHA V BETA 3
EP1249244A1 (en) * 2001-04-13 2002-10-16 Universiteit Gent Therapeutic compositions for the treatment of a disease modulated by the G-actin / F-actin equilibrium, especially a respiratory tract disease
KR20040026680A (ko) 2001-07-09 2004-03-31 콤비네이토릭스, 인코포레이티드 염증 질환 치료용 조합
CA2458677A1 (en) * 2001-08-30 2003-03-13 Praecis Pharmaceuticals Incorporated Methods and compositions for treating inflammatory disorders
US20080051348A1 (en) * 2002-02-06 2008-02-28 Regenerx Biopharmaceuticals, Inc. Treatment of infections and other disorders
EP1497322A4 (en) * 2002-02-06 2006-11-08 Regenerx Biopharmaceuticals TREATMENT OF INFECTIONS AND OTHER DISORDERS
WO2003088811A2 (en) 2002-04-16 2003-10-30 The Brigham And Women's Hospital, Inc. Gelsolin as a prognostic marker of artherosclerotic diseases
AU2003253014A1 (en) 2002-06-21 2004-01-06 Innogenetics N.V. Method for the diagnosis and differential diagnosis of neurological diseases
WO2004023973A2 (en) 2002-09-12 2004-03-25 Incyte Corporation Molecules for diagnostics and therapeutics
US9063155B2 (en) * 2003-02-21 2015-06-23 Medvet Science Pty Ltd Immunotherapeutic method of treating neoplastic conditions
CA2527916A1 (en) 2003-03-14 2004-09-30 Aaron B. Kantor Biological markers for diagnosing rheumatoid arthritis
GB0327723D0 (en) * 2003-09-15 2003-12-31 Vectura Ltd Pharmaceutical compositions
US9408891B2 (en) * 2003-11-12 2016-08-09 The Trustees Of The University Of Pennsylvania Methods of using gelsolin to treat or prevent bacterial sepsis
CA2545718C (en) * 2003-11-12 2016-05-10 The Trustees Of The University Of Pennsylvania Methods of using gelsolin to treat or prevent bacterial sepsis
AU2004308378B2 (en) * 2003-12-22 2010-05-13 Regenerx Biopharmaceuticals, Inc. Method of treating or preventing biological or immunological responses to a reactive chemical or biological or toxic agent
ES2541683T3 (es) 2004-02-27 2015-07-23 F. Hoffmann-La Roche Ag Método para evaluar la artritis reumatoide mediante la medición del factor reumatoide y la interleuquina-6
CA2860173C (en) 2004-05-12 2021-12-14 The Brigham And Women's Hospital, Inc. Determining plasma gelsolin level to predict risk of developing infection
SI1929297T1 (sl) 2005-09-29 2013-06-28 Caprion Proteomics Usa, Llc Bioloĺ ki oznaäśevalci pri multipli sklerozi in metode za njihovo uporabo
PT2002258T (pt) 2006-03-15 2017-12-18 The Brigham And Women`S Hospital Inc Utilização de gelsolina para o tratamento da esclerose múltipla e para o diagnóstico de doenças neurológicas
JP5322917B2 (ja) 2006-03-15 2013-10-23 ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッド 炎症性疾患の診断および処置のためのゲルゾリンの使用
ES2531827T3 (es) 2008-01-25 2015-03-20 The General Hospital Corporation Usos terapéuticos de gelsolina en insuficiencia renal
KR101568323B1 (ko) 2014-01-08 2015-11-12 한국원자력의학원 겔솔린을 유효성분으로 포함하는 수지상세포 분화 유도용 조성물 및 이의 분화 유도방법
WO2016033187A1 (en) 2014-08-26 2016-03-03 The Brigham And Women's Hospital, Inc. Use of gelsolin in the treatment and diagnosis of sickle cell disease

Also Published As

Publication number Publication date
PT1755661E (pt) 2014-06-03
US10022424B2 (en) 2018-07-17
PL1755661T3 (pl) 2014-10-31
US20080261260A1 (en) 2008-10-23
CA2607686C (en) 2014-11-04
US20080118945A1 (en) 2008-05-22
CA2607686A1 (en) 2005-12-01
JP5905183B2 (ja) 2016-04-20
KR101300929B1 (ko) 2013-08-27
AU2005244865A1 (en) 2005-12-01
JP2014196346A (ja) 2014-10-16
EP1755661B1 (en) 2014-03-12
JP2012067125A (ja) 2012-04-05
ES2730728T3 (es) 2019-11-12
ES2464444T3 (es) 2014-06-02
WO2005112970A3 (en) 2006-03-16
EP2335722A3 (en) 2012-06-13
WO2005112970A2 (en) 2005-12-01
US20060009386A1 (en) 2006-01-12
CN1980694A (zh) 2007-06-13
EP2335722B1 (en) 2019-03-13
EP1755661A2 (en) 2007-02-28
KR20070015457A (ko) 2007-02-02
KR101314461B1 (ko) 2013-10-07
CA2860173C (en) 2021-12-14
JP6688671B2 (ja) 2020-04-28
DK1755661T3 (da) 2014-06-16
EP2335722A2 (en) 2011-06-22
CA2860173A1 (en) 2005-12-01
JP2016138139A (ja) 2016-08-04
JP2007537292A (ja) 2007-12-20
KR20120061990A (ko) 2012-06-13
EP1755661A4 (en) 2008-02-20
CN1980694B (zh) 2012-09-26
US20080125370A1 (en) 2008-05-29

Similar Documents

Publication Publication Date Title
HK1102758A1 (zh) 膠溶蛋白是用來治療傳染病
HK1221956A1 (zh) 用於治療感染的鹵代類苯酞化硼
GB0506707D0 (en) Hyperbaric dressing
ZA200800464B (en) Peptides for use in the treatment of obesity
GB2423775B (en) Portable enclosure in particular for sanitary purposes
GB0516254D0 (en) Improvements in devices
GB0400700D0 (en) Compounds useful in therapy
GB0407910D0 (en) Improvements in or relating to devices
GB0415181D0 (en) Compounds for use in the treatment of infection
EP1830972A4 (en) PROCESSING PROCESS
GB0426141D0 (en) Treatment
GB0512040D0 (en) Computer architecture suitable for use in space
GB0417360D0 (en) Improvements in devices
GB0428089D0 (en) Improvements in automotive technology
GB0420985D0 (en) Improvements in image processing
GB0311936D0 (en) Improvements in devices
GB0803201D0 (en) Two-part dressing suitable for use in surgery
GB0516610D0 (en) Compounds for use in therapy
GB0409173D0 (en) Improvements in or relating to devices
GB0514849D0 (en) Treatment for kerationlytic and other fungal infections
GB0417475D0 (en) Improvements in devices
GB0522475D0 (en) Improvements in latches
GB0416876D0 (en) Compound and use in treatment
GB0401384D0 (en) Compounds useful in therapy
GB0423117D0 (en) Compounds for use in therapy