PT1755661E - A utilização de gelsolina para o tratamento de infeções - Google Patents
A utilização de gelsolina para o tratamento de infeções Download PDFInfo
- Publication number
- PT1755661E PT1755661E PT57503922T PT05750392T PT1755661E PT 1755661 E PT1755661 E PT 1755661E PT 57503922 T PT57503922 T PT 57503922T PT 05750392 T PT05750392 T PT 05750392T PT 1755661 E PT1755661 E PT 1755661E
- Authority
- PT
- Portugal
- Prior art keywords
- gelsolin
- treating infections
- infections
- treating
- Prior art date
Links
- 102000004878 Gelsolin Human genes 0.000 title 1
- 108090001064 Gelsolin Proteins 0.000 title 1
- 208000015181 infectious disease Diseases 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/085—Staphylococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/002—Protozoa antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Marine Sciences & Fisheries (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- Pulmonology (AREA)
- AIDS & HIV (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Toxicology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US57023304P | 2004-05-12 | 2004-05-12 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT1755661E true PT1755661E (pt) | 2014-06-03 |
Family
ID=35428845
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT57503922T PT1755661E (pt) | 2004-05-12 | 2005-05-12 | A utilização de gelsolina para o tratamento de infeções |
Country Status (13)
Country | Link |
---|---|
US (4) | US10022424B2 (pt) |
EP (2) | EP2335722B1 (pt) |
JP (4) | JP5905183B2 (pt) |
KR (2) | KR101314461B1 (pt) |
CN (1) | CN1980694B (pt) |
AU (1) | AU2005244865A1 (pt) |
CA (2) | CA2860173C (pt) |
DK (1) | DK1755661T3 (pt) |
ES (2) | ES2464444T3 (pt) |
HK (1) | HK1102758A1 (pt) |
PL (1) | PL1755661T3 (pt) |
PT (1) | PT1755661E (pt) |
WO (1) | WO2005112970A2 (pt) |
Families Citing this family (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20080113025A1 (en) * | 1998-11-02 | 2008-05-15 | Elan Pharma International Limited | Compositions comprising nanoparticulate naproxen and controlled release hydrocodone |
JP4613275B2 (ja) * | 1998-11-02 | 2011-01-12 | エラン ファーマ インターナショナル,リミティド | 多粒子改質放出組成物 |
US6849605B1 (en) | 1999-03-05 | 2005-02-01 | The Trustees Of University Technology Corporation | Inhibitors of serine protease activity, methods and compositions for treatment of viral infections |
CA2536918A1 (en) | 2003-08-26 | 2005-03-03 | Leland Shapiro | Compositions of, and methods for, alpha-1 antitrypsin fc fusion molecules |
US20070238655A1 (en) * | 2003-11-12 | 2007-10-11 | The Trustees Of The University Of Pennsylvania | Methods of Using Gelsolin to Treat or Prevent Bacterial Sepsis |
US9408891B2 (en) * | 2003-11-12 | 2016-08-09 | The Trustees Of The University Of Pennsylvania | Methods of using gelsolin to treat or prevent bacterial sepsis |
JP5905183B2 (ja) * | 2004-05-12 | 2016-04-20 | ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッドThe Brigham and Women’s Hospital, Inc. | 感染を処置するためのゲルソリンの使用 |
DK2343304T3 (en) | 2005-02-16 | 2015-06-29 | Anacor Pharmaceuticals Inc | BIOCIDE BORONOPHTHALIDE COMPOUNDS |
WO2007079312A2 (en) * | 2005-12-02 | 2007-07-12 | Regents Of The University Of Colorado | Compositions and methods for treating actin-mediated medical conditions |
RU2008131324A (ru) | 2005-12-30 | 2010-02-10 | Анакор Фармасьютикалз, Инк. (Us) | Борсодержащие малые молекулы |
CA2933994A1 (en) | 2006-02-16 | 2007-08-23 | Anacor Pharmaceuticals, Inc. | Boron-containing small molecules as anti-inflammatory agents |
DK3279663T3 (da) | 2006-03-15 | 2021-10-18 | Brigham & Womens Hospital Inc | Anvendelse af gelsolin til diagnosticering og behandling af inflammationssygdomme |
AU2013202205C1 (en) * | 2006-03-15 | 2018-05-17 | The Brigham And Women's Hospital, Inc. | Use of Gelsolin to Diagnose and Treat Inflammatory Disease |
PL2002258T3 (pl) | 2006-03-15 | 2018-06-29 | The Brigham And Women's Hospital, Inc. | Zastosowanie gelsoliny do leczenia stwardnienia rozsianego i diagnozowania chorób neurologicznych |
JO3396B1 (ar) * | 2007-06-20 | 2019-10-20 | Anacor Pharmaceuticals Inc | جزيئات صغيرة تحتوي على البورون |
PL2250280T3 (pl) * | 2008-01-25 | 2015-06-30 | Massachusetts Gen Hospital | Terapeutyczne zastosowania gelsoliny w niewydolności nerek |
RU2547441C2 (ru) | 2008-03-06 | 2015-04-10 | Анакор Фармасьютикалз, Инк. | Борсодержащие малые молекулы в качестве противовоспалительных агентов |
WO2009140309A2 (en) * | 2008-05-12 | 2009-11-19 | Anacor Pharmaceuticals, Inc. | Boron-containing small molecules |
EP2348863A4 (en) * | 2008-09-04 | 2012-03-07 | Anacor Pharmaceuticals Inc | BORN SMALL MOLECULES |
WO2010028005A1 (en) | 2008-09-04 | 2010-03-11 | Anacor Pharmaceuticals, Inc. | Boron-containing small molecules |
US9493489B2 (en) * | 2008-10-15 | 2016-11-15 | Anacor Pharmaceuticals, Inc. | Boron-containing small molecules as anti-protozoal agents |
BRPI0922566A2 (pt) * | 2008-12-17 | 2017-03-28 | Anacor Pharmaceuticals Inc | polimorfo cristalino, composição farmacêutica, composto, e, métodos para preparar um composto, e para tratar uma doença. |
WO2011017125A1 (en) * | 2009-07-28 | 2011-02-10 | Anacor Pharmaceuticals, Inc. | Trisubstituted boron-containing molecules |
US9440994B2 (en) * | 2009-08-14 | 2016-09-13 | Anacor Pharmaceuticals, Inc. | Boron containing small molecules as antiprotozoal agents |
WO2011022337A1 (en) * | 2009-08-19 | 2011-02-24 | Anacor Pharmaceuticals, Inc. | Boron-containing small molecules as antiprotozoal agents |
WO2011037731A1 (en) * | 2009-09-25 | 2011-03-31 | Anacor Pharmaceuticals, Inc. | Boron containing small molecules |
US9346834B2 (en) | 2009-10-20 | 2016-05-24 | Anacor Pharmaceuticals, Inc. | Boron-containing small molecules as antiprotozoal agents |
US8461134B2 (en) * | 2009-11-11 | 2013-06-11 | Anacor Pharmaceuticals, Inc. | Boron-containing small molecules |
WO2011094450A1 (en) | 2010-01-27 | 2011-08-04 | Anacor Pharmaceuticals, Inc | Boron-containing small molecules |
AP2012006482A0 (en) | 2010-03-19 | 2012-10-31 | Anacor Pharmacueticals Inc | Boron-containing small molecules as anti-protozoalagent |
EA033311B1 (ru) | 2010-09-07 | 2019-09-30 | Анакор Фармасьютикалс, Инк. | Производные бензоксаборола в качестве антибактериальных средств |
US20120316211A1 (en) * | 2011-05-11 | 2012-12-13 | The Board or Regents of the University of Texas System | Diagnostic Methods for Assessing Risk of Chagas Disease and Heart Failure |
CA2839917A1 (en) | 2011-06-24 | 2012-12-27 | The Regents Of The University Of Colorado, A Body Corporate | Compositions, methods and uses for alpha-1 antitrypsin fusion molecules |
JP2015504675A (ja) | 2012-01-10 | 2015-02-16 | ザ リージェンツ オブ ザ ユニバーシティ オブ コロラド,ア ボディー コーポレイトTHE REGENTS OF THE UNIVERSITY OF COLORADO,a body corporate | アルファ−1アンチトリプシン融合分子の組成物、方法、及び使用 |
WO2014108872A1 (en) * | 2013-01-14 | 2014-07-17 | Wockhardt Limited | Compositions and methods for treating bacterial infections |
WO2016033187A1 (en) * | 2014-08-26 | 2016-03-03 | The Brigham And Women's Hospital, Inc. | Use of gelsolin in the treatment and diagnosis of sickle cell disease |
FR3036188B1 (fr) * | 2015-05-12 | 2019-06-07 | Biomerieux | Prediction du risque de developper, pour des patients admis en service de reanimation, une infection disseminee |
TW201718627A (zh) | 2015-06-11 | 2017-06-01 | 梅茲製藥有限兩合公司 | 重組梭菌神經毒素及其使用與形成方法、包括其之醫藥組合物及對應其之前驅物、編碼前驅物之核酸序列及其獲得方法與前驅物之形成方法、載體與包括核酸序列之重組宿主細胞 |
JP2019507118A (ja) | 2016-03-02 | 2019-03-14 | メルツ ファルマ ゲーエムベーハー ウント コンパニー カーゲーアーアー | ボツリヌス毒素を含む組成物 |
US11447506B2 (en) | 2016-05-09 | 2022-09-20 | Anacor Pharmaceuticals, Inc. | Crystal forms of crisaborole in free form and preparation method and use thereof |
WO2018233813A1 (en) | 2017-06-20 | 2018-12-27 | Merz Pharma Gmbh & Co. Kgaa | NOVEL RECOMBINANT BOTULINUM TOXINS WITH INCREASED DURATION |
ES2930237T3 (es) | 2017-07-06 | 2022-12-09 | Merz Pharma Gmbh & Co Kgaa | Neurotoxinas botulínicas recombinantes nuevas con mayor duración de efectos |
IT201700083044A1 (it) * | 2017-07-20 | 2019-01-20 | Laura Stronati | “uso della gelsolina come marcatore diagnostico e prognostico delle malattie infiammatorie intestinali” |
CN111317739A (zh) * | 2018-12-14 | 2020-06-23 | 复旦大学 | 依托红霉素在制备特异性抑制病毒感染的药物中的用途 |
EP3965799A4 (en) * | 2019-06-21 | 2023-02-01 | Bioaegis Therapeutics Inc. | SYNERGIC COMPOSITIONS AND METHODS OF TREATING INFECTIONS |
Family Cites Families (55)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US565659A (en) * | 1896-08-11 | Driving-gearing for cycles | ||
US5071773A (en) | 1986-10-24 | 1991-12-10 | The Salk Institute For Biological Studies | Hormone receptor-related bioassays |
CA2016227A1 (en) | 1989-05-18 | 1990-11-18 | Xandra O. Breakefield | Genetic diagnosis of torsion dystonia |
US5464817A (en) * | 1990-04-11 | 1995-11-07 | Brigham And Women's Hospital | Method for reducing the viscosity of pathological mucoid airway contents in the respiratory tract comprising administering actin-binding compounds with or without DNASE I |
WO1991015770A1 (en) | 1990-04-11 | 1991-10-17 | The General Hospital Corporation | Therapeutic uses of actin-binding compounds |
EP0481070A1 (en) * | 1990-05-04 | 1992-04-22 | Biogen, Inc. | Multimeric gelsolin fusion constructs |
US5571511A (en) | 1990-10-22 | 1996-11-05 | The U.S. Government | Broadly reactive opsonic antibodies that react with common staphylococcal antigens |
CA2082951C (en) | 1991-03-15 | 1999-12-21 | Robert M. Platz | Pulmonary administration of granulocyte colony stimulating factor |
US5360350A (en) | 1991-08-23 | 1994-11-01 | The Whitaker Corporation | Sealant compositions and sealed electrical connectors |
AU4801393A (en) * | 1992-08-03 | 1994-03-03 | New York University | Cloning, expression and uses for neurocan as a chondroitin sulfate proteoglycan |
US5691160A (en) | 1992-08-14 | 1997-11-25 | Biogen, Inc. | Effects of actin filaments of fibrin clot structure and lysis |
WO1994008049A1 (en) | 1992-10-01 | 1994-04-14 | The General Hospital Corporation | Functional assay for tumor suppressor genes |
US5830436A (en) * | 1993-03-30 | 1998-11-03 | Duke University | Method of mucociliary clearance in cystic fibrosis patients using alkylaryl polyether alcohol polymers |
US5593964A (en) * | 1993-10-07 | 1997-01-14 | The George Washington University Medical Center | Method of treating septic shock by preventing actin polymerization |
JP3914272B2 (ja) * | 1993-12-28 | 2007-05-16 | 中外製薬株式会社 | アドゼベリンをコードする遺伝子 |
CA2184385A1 (en) * | 1994-03-11 | 1995-09-14 | Philip Davies | Composition for the treatment of lung disease |
US5451569A (en) | 1994-04-19 | 1995-09-19 | Hong Kong University Of Science And Technology R & D Corporation Limited | Pulmonary drug delivery system |
US5846743A (en) | 1995-02-22 | 1998-12-08 | Brigham And Women's Hospital, Inc. | Polyphoshoinositide binding peptides for intracellular drug delivery |
CA2214247C (en) | 1995-03-14 | 2004-02-10 | Praecis Pharmaceuticals Incorporated | Modulators of amyloid aggregation |
US5804427A (en) | 1995-05-19 | 1998-09-08 | University Of Massachusetts | Cytokine-, stress-, and oncoprotein-activated human protein kinase kinases |
US5925529A (en) | 1995-06-07 | 1999-07-20 | The Regents Of The University Of California | Method for discovery of peptide agonists |
US5569588A (en) | 1995-08-09 | 1996-10-29 | The Regents Of The University Of California | Methods for drug screening |
US5750353A (en) | 1995-12-11 | 1998-05-12 | New England Medical Center Hospitals, Inc. | Assay for non-peptide agonists to peptide hormone receptors |
US6179489B1 (en) * | 1997-04-04 | 2001-01-30 | Texas Instruments Incorporated | Devices, methods, systems and software products for coordination of computer main microprocessor and second microprocessor coupled thereto |
WO1998004589A2 (en) * | 1996-07-30 | 1998-02-05 | Biogen, Inc. | Production of recombinant plasma gelsolin containing a disulfide bond |
DK0941108T3 (da) | 1996-12-04 | 2002-11-18 | Renovo Ltd | Sårheling og behandling af fibrose |
PT1003501E (pt) | 1997-04-02 | 2005-07-29 | Brigham & Womens Hospital | Utilizacao de um agente para reduzir o risco de doencas cardiovasculares |
AU3395900A (en) * | 1999-03-12 | 2000-10-04 | Human Genome Sciences, Inc. | Human lung cancer associated gene sequences and polypeptides |
EP1239877B1 (en) | 1999-10-06 | 2008-01-09 | Abbott GmbH & Co. KG | Composition comprising a tnf-alpha inhibitor and an integrin alphavbeta3 receptor antagonist |
US6671818B1 (en) * | 1999-11-22 | 2003-12-30 | Accenture Llp | Problem isolation through translating and filtering events into a standard object format in a network based supply chain |
US6802063B1 (en) * | 2000-07-13 | 2004-10-05 | International Business Machines Corporation | 64-bit open firmware implementation and associated api |
AU2002225219A1 (en) | 2001-01-26 | 2002-08-06 | Oxford Glycosciences (Uk) Ltd | Diagnosis and treatment of multiple sclerosis |
CA2439852A1 (en) | 2001-03-02 | 2002-09-12 | Christine Dingivan | Methods of preventing or treating inflammatory or autoimmune disorders by administering integrin alphav beta3 antagonists |
EP1249244A1 (en) * | 2001-04-13 | 2002-10-16 | Universiteit Gent | Therapeutic compositions for the treatment of a disease modulated by the G-actin / F-actin equilibrium, especially a respiratory tract disease |
RU2300379C2 (ru) | 2001-07-09 | 2007-06-10 | Комбинаторкс, Инкорпорейтед | Комбинации для лечения воспалительных заболеваний |
US20030083262A1 (en) * | 2001-08-30 | 2003-05-01 | Praecis Pharmaceuticals Inc. | Methods and compositions for treating inflammatory disorders |
US20080051348A1 (en) * | 2002-02-06 | 2008-02-28 | Regenerx Biopharmaceuticals, Inc. | Treatment of infections and other disorders |
EP1497322A4 (en) * | 2002-02-06 | 2006-11-08 | Regenerx Biopharmaceuticals | TREATMENT OF INFECTIONS AND OTHER DISORDERS |
WO2003088811A2 (en) | 2002-04-16 | 2003-10-30 | The Brigham And Women's Hospital, Inc. | Gelsolin as a prognostic marker of artherosclerotic diseases |
AU2003253014A1 (en) | 2002-06-21 | 2004-01-06 | Innogenetics N.V. | Method for the diagnosis and differential diagnosis of neurological diseases |
WO2004023973A2 (en) | 2002-09-12 | 2004-03-25 | Incyte Corporation | Molecules for diagnostics and therapeutics |
JP5339676B2 (ja) * | 2003-02-21 | 2013-11-13 | メドベット サイエンス ピーティーワイ. リミテッド | 細胞を検出する方法、およびこれに有用な薬剤 |
AU2004222345A1 (en) | 2003-03-14 | 2004-09-30 | Ppd Biomarker Discovery Sciences, Llc | Biological markers for diagnosing rheumatoid arthritis |
GB0327723D0 (en) * | 2003-09-15 | 2003-12-31 | Vectura Ltd | Pharmaceutical compositions |
US20070238655A1 (en) * | 2003-11-12 | 2007-10-11 | The Trustees Of The University Of Pennsylvania | Methods of Using Gelsolin to Treat or Prevent Bacterial Sepsis |
US9408891B2 (en) * | 2003-11-12 | 2016-08-09 | The Trustees Of The University Of Pennsylvania | Methods of using gelsolin to treat or prevent bacterial sepsis |
EP1706136A4 (en) * | 2003-12-22 | 2009-09-16 | Regenerx Biopharmaceuticals | PROCESS FOR TREATING OR PREVENTING BIOLOGICAL OR IMMUNE RESPONSES TO A REACTIVE CHEMICAL OR BIOLOGICAL OR TOXIC SUBSTANCE |
WO2005085859A1 (en) | 2004-02-27 | 2005-09-15 | Roche Diagnostics Gmbh | Method of assessing rheumatoid arthritis by measuring rheumatoid factor and interleukin-6 |
JP5905183B2 (ja) | 2004-05-12 | 2016-04-20 | ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッドThe Brigham and Women’s Hospital, Inc. | 感染を処置するためのゲルソリンの使用 |
US20100062471A1 (en) | 2005-09-29 | 2010-03-11 | Ppd Biomarker Discovery Sciences Llc | Biomarkers for Multiple Sclerosis and Methods of Use Thereof |
DK3279663T3 (da) | 2006-03-15 | 2021-10-18 | Brigham & Womens Hospital Inc | Anvendelse af gelsolin til diagnosticering og behandling af inflammationssygdomme |
PL2002258T3 (pl) | 2006-03-15 | 2018-06-29 | The Brigham And Women's Hospital, Inc. | Zastosowanie gelsoliny do leczenia stwardnienia rozsianego i diagnozowania chorób neurologicznych |
PL2250280T3 (pl) | 2008-01-25 | 2015-06-30 | Massachusetts Gen Hospital | Terapeutyczne zastosowania gelsoliny w niewydolności nerek |
KR101568323B1 (ko) | 2014-01-08 | 2015-11-12 | 한국원자력의학원 | 겔솔린을 유효성분으로 포함하는 수지상세포 분화 유도용 조성물 및 이의 분화 유도방법 |
WO2016033187A1 (en) | 2014-08-26 | 2016-03-03 | The Brigham And Women's Hospital, Inc. | Use of gelsolin in the treatment and diagnosis of sickle cell disease |
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- 2005-05-12 KR KR1020067026072A patent/KR101314461B1/ko active IP Right Grant
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