HK1102197A1 - Hif prolyl hydroxylase activity assay - Google Patents
Hif prolyl hydroxylase activity assayInfo
- Publication number
- HK1102197A1 HK1102197A1 HK07110215.1A HK07110215A HK1102197A1 HK 1102197 A1 HK1102197 A1 HK 1102197A1 HK 07110215 A HK07110215 A HK 07110215A HK 1102197 A1 HK1102197 A1 HK 1102197A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- activity assay
- prolyl hydroxylase
- hydroxylase activity
- hif prolyl
- methods
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/902—Oxidoreductases (1.)
- G01N2333/90245—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Enzymes And Modification Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57532404P | 2004-05-28 | 2004-05-28 | |
| PCT/US2005/018577 WO2005118836A2 (en) | 2004-05-28 | 2005-05-26 | Hif prolyl hydroxylase activity assay |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1102197A1 true HK1102197A1 (en) | 2007-11-09 |
Family
ID=34979114
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK07110215.1A HK1102197A1 (en) | 2004-05-28 | 2007-09-20 | Hif prolyl hydroxylase activity assay |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20080113383A1 (de) |
| EP (1) | EP1766047B1 (de) |
| JP (1) | JP2008500834A (de) |
| AT (1) | ATE443775T1 (de) |
| AU (1) | AU2005250412B2 (de) |
| CA (1) | CA2567619A1 (de) |
| DE (1) | DE602005016800D1 (de) |
| ES (1) | ES2332798T3 (de) |
| HK (1) | HK1102197A1 (de) |
| IL (1) | IL179441A (de) |
| NZ (1) | NZ551632A (de) |
| WO (1) | WO2005118836A2 (de) |
| ZA (1) | ZA200610164B (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2044028B1 (de) | 2006-01-27 | 2012-05-16 | Fibrogen, Inc. | Cyanoisochinoline zur stabilisierung des hypoxie-induzierten faktors (hif) |
| US7588924B2 (en) | 2006-03-07 | 2009-09-15 | Procter & Gamble Company | Crystal of hypoxia inducible factor 1 alpha prolyl hydroxylase |
| RU2461557C2 (ru) | 2006-04-04 | 2012-09-20 | Файброджен, Инк. | Соединения пирроло- и тиазолопиридина (варианты) и фармацевтическая композиция на их основе |
| DE602007009992D1 (de) | 2006-06-26 | 2010-12-02 | Warner Chilcott Co Llc | Prolylhydroxylase-hemmer und verfahren zu ihrer anwendung |
| ES2533128T3 (es) | 2009-11-06 | 2015-04-07 | Aerpio Therapeutics Inc. | Inhibidores de la prolilhidroxilasa |
| CN103608346B (zh) | 2011-02-02 | 2016-06-15 | 菲布罗根有限公司 | 作为缺氧诱导因子(hif)羟化酶抑制剂的萘啶衍生物 |
| GB201102659D0 (en) | 2011-02-15 | 2011-03-30 | Isis Innovation | Assay |
| EP2717870B1 (de) | 2011-06-06 | 2017-09-27 | Akebia Therapeutics Inc. | Zusammensetzung zur stabilisierung des durch hypoxie induzierbaren faktors-2 alpha verwendbar zur behandlung von krebs |
| NO2686520T3 (de) | 2011-06-06 | 2018-03-17 | ||
| GB201113101D0 (en) | 2011-07-28 | 2011-09-14 | Isis Innovation | Assay |
| US9409892B2 (en) | 2012-03-09 | 2016-08-09 | Fibrogen, Inc. | 4-hydroxy-isoquinoline compounds as HIF hydroxylase inhibitors |
| HUE034409T2 (en) | 2012-07-16 | 2018-02-28 | Fibrogen Inc | Process for the preparation of isoquinoline compounds |
| KR102149380B1 (ko) | 2012-07-16 | 2020-08-28 | 피브로겐, 인크. | 프롤릴 하이드록실라제 억제제 [(4-하이드록시-1-메틸-7-페녹시-아이소퀴놀린-3-카보닐)-아미노]-아세트산의 결정형 |
| PE20160194A1 (es) | 2013-06-13 | 2016-04-20 | Akebia Therapeutics Inc | Composiciones y metodos para tratar anemia |
| TW201632504A (zh) | 2015-01-23 | 2016-09-16 | 阿克比治療有限公司 | ２－（５－（３－氟苯基）－３－羥吡啶醯胺基）乙酸之固體形式、其組合物及其用途 |
| EA036920B1 (ru) | 2015-04-01 | 2021-01-15 | Экебиа Терапьютикс, Инк. | Композиции и способы для лечения анемии |
| TWI822776B (zh) | 2018-05-09 | 2023-11-21 | 美商阿克比治療有限公司 | 用於製備2-[[5-(3-氯苯基)-3-羥基吡啶-2-羰基]胺基]乙酸之方法 |
| CN114577945B (zh) * | 2022-03-10 | 2023-06-02 | 中国科学院兰州化学物理研究所 | 一种从中药提取物中筛选脯氨酰羟化酶2抑制剂的胶束电动色谱方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2002241154A1 (en) * | 2001-03-21 | 2002-10-03 | Isis Innovation Ltd. | Assays, methods and means relating to hypoxia inducible factor (hif) hydroxylase |
| CA2916093C (en) * | 2001-12-06 | 2020-11-03 | Fibrogen, Inc. | Use of hif prolyl hydroxylase inhibitors for treating neurological disorders |
-
2005
- 2005-05-26 DE DE602005016800T patent/DE602005016800D1/de active Active
- 2005-05-26 US US11/597,261 patent/US20080113383A1/en not_active Abandoned
- 2005-05-26 ES ES05755214T patent/ES2332798T3/es active Active
- 2005-05-26 EP EP05755214A patent/EP1766047B1/de active Active
- 2005-05-26 ZA ZA200610164A patent/ZA200610164B/en unknown
- 2005-05-26 AT AT05755214T patent/ATE443775T1/de not_active IP Right Cessation
- 2005-05-26 AU AU2005250412A patent/AU2005250412B2/en not_active Ceased
- 2005-05-26 WO PCT/US2005/018577 patent/WO2005118836A2/en active Application Filing
- 2005-05-26 JP JP2007515346A patent/JP2008500834A/ja not_active Ceased
- 2005-05-26 NZ NZ551632A patent/NZ551632A/en unknown
- 2005-05-26 CA CA002567619A patent/CA2567619A1/en not_active Abandoned
-
2006
- 2006-11-21 IL IL179441A patent/IL179441A/en not_active IP Right Cessation
-
2007
- 2007-09-20 HK HK07110215.1A patent/HK1102197A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005118836A2 (en) | 2005-12-15 |
| EP1766047A2 (de) | 2007-03-28 |
| ZA200610164B (en) | 2008-02-27 |
| IL179441A (en) | 2010-12-30 |
| JP2008500834A (ja) | 2008-01-17 |
| ES2332798T3 (es) | 2010-02-12 |
| WO2005118836A3 (en) | 2006-04-06 |
| EP1766047B1 (de) | 2009-09-23 |
| IL179441A0 (en) | 2007-05-15 |
| NZ551632A (en) | 2009-09-25 |
| AU2005250412A1 (en) | 2005-12-15 |
| DE602005016800D1 (de) | 2009-11-05 |
| ATE443775T1 (de) | 2009-10-15 |
| CA2567619A1 (en) | 2005-12-15 |
| AU2005250412B2 (en) | 2009-09-17 |
| US20080113383A1 (en) | 2008-05-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL179441A0 (en) | Hif prolyl hydroxylase activity assay | |
| WO2006038208A3 (en) | Agents capable of downregulating an msf-a - dependent hif-1α and use thereof in cancer treatment | |
| EP1687283A4 (de) | Für die bestimmung von fk506 geeignetes verfahren und zusammensetzung | |
| DE60131262D1 (en) | Ubiquitin-ligase-assay | |
| WO2005082341A3 (en) | NON-PEPTIDYL AGENTS WITH pHSP20-LIKE ACTIVITY, AND USES THEREOF | |
| WO2007025169A3 (en) | Hif inhibitors | |
| CY1110337T1 (el) | Παρασκευη πρεγκαμπαλινης και σχετικων ενωσεων | |
| WO2005012337A3 (en) | Antigenic peptides of sars coronavirus and uses thereof | |
| MX2010010209A (es) | 4-hidroxipirimidina-5-carboxamidas sustituidas. | |
| TW200636245A (en) | Colorimetric sensors constructed of diacetylene materials | |
| EP1941060A4 (de) | Protein-demethylasen mit einer jmjc-domäne | |
| MXPA03007786A (es) | Amplificacion de sonda circular usando iniciadores de transferencia de energia. | |
| WO2005019470A3 (en) | Detecting and profiling molecular complexes | |
| SG155931A1 (en) | Wnt proteins and detection and treatment of cancer | |
| MA30922B1 (fr) | Anticorps d'agonistes de trkb et leurs utilisations | |
| EA201391627A1 (ru) | Анализ на наличие лизилоксидазоподобных белков 2 и способы его применения | |
| WO2004111081A3 (en) | Antigenic peptides of sars coronavirus and uses thereof | |
| MX2007002277A (es) | Metodos para formar retinoides y usos de los mismos. | |
| WO2009082445A3 (en) | Novel devices for the detection of the presence and/or activity of proteases in biological samples | |
| GB2388190B (en) | Methods for measuring enzyme activity | |
| DK1540338T3 (da) | Bioækvivalenstest for jernholdige formuleringer | |
| WO2005012901A3 (en) | Method for measuring aromatase activity | |
| ATE447628T1 (de) | Einzelsequenzhybridisierungssonden | |
| WO2007121209A3 (en) | Methods and devices for non-invasive analyte measurement | |
| WO2003087054A3 (en) | Methods for identifying compounds that modulate enzymatic activity |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20130526 |