HK1100483A1 - 1-benzoyl-piperazine derivatives as glycine uptake inhibitors for the treatment of psychoses - Google Patents
1-benzoyl-piperazine derivatives as glycine uptake inhibitors for the treatment of psychosesInfo
- Publication number
- HK1100483A1 HK1100483A1 HK07105684.3A HK07105684A HK1100483A1 HK 1100483 A1 HK1100483 A1 HK 1100483A1 HK 07105684 A HK07105684 A HK 07105684A HK 1100483 A1 HK1100483 A1 HK 1100483A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- psychoses
- benzoyl
- treatment
- piperazine derivatives
- uptake inhibitors
- Prior art date
Links
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 title 2
- 239000004471 Glycine Substances 0.000 title 1
- 208000028017 Psychotic disease Diseases 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- VUNXBQRNMNVUMV-UHFFFAOYSA-N phenyl(piperazin-1-yl)methanone Chemical class C=1C=CC=CC=1C(=O)N1CCNCC1 VUNXBQRNMNVUMV-UHFFFAOYSA-N 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
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- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/112—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
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- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
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- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
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Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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EP03019682 | 2003-09-09 | ||
PCT/EP2004/009699 WO2005023261A1 (fr) | 2003-09-09 | 2004-08-31 | Derives de 1-benzoyl-piperazine comme inhibiteurs du recaptage de la glycine pour le traitement de psychoses |
Publications (1)
Publication Number | Publication Date |
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HK1100483A1 true HK1100483A1 (en) | 2007-09-21 |
Family
ID=34259148
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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HK07105684.3A HK1100483A1 (en) | 2003-09-09 | 2007-05-29 | 1-benzoyl-piperazine derivatives as glycine uptake inhibitors for the treatment of psychoses |
Country Status (28)
Country | Link |
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US (1) | US7462617B2 (fr) |
EP (1) | EP1703909B1 (fr) |
JP (1) | JP4563387B2 (fr) |
KR (1) | KR100774621B1 (fr) |
CN (1) | CN100522171C (fr) |
AR (1) | AR045587A1 (fr) |
AT (1) | ATE428424T1 (fr) |
AU (1) | AU2004269892B2 (fr) |
BR (1) | BRPI0413536B8 (fr) |
CA (1) | CA2538135C (fr) |
CO (1) | CO5680430A2 (fr) |
DE (1) | DE602004020674D1 (fr) |
DK (1) | DK1703909T3 (fr) |
ES (1) | ES2322651T3 (fr) |
HK (1) | HK1100483A1 (fr) |
HR (1) | HRP20090265T1 (fr) |
IL (1) | IL174075A (fr) |
MX (1) | MXPA06002672A (fr) |
MY (1) | MY140470A (fr) |
NO (1) | NO20060975L (fr) |
NZ (1) | NZ545613A (fr) |
PL (1) | PL1703909T3 (fr) |
PT (1) | PT1703909E (fr) |
RU (1) | RU2355683C2 (fr) |
SI (1) | SI1703909T1 (fr) |
TW (1) | TW200526601A (fr) |
WO (1) | WO2005023261A1 (fr) |
ZA (1) | ZA200601988B (fr) |
Families Citing this family (55)
Publication number | Priority date | Publication date | Assignee | Title |
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DE2611705A1 (de) * | 1976-03-18 | 1977-09-22 | Josef Dipl Chem Dr Rer N Klosa | N-5-(nitrofurfuryliden-)-1-amino- hydantoin enthaltende kristalloesungsmittel |
IT1176613B (it) * | 1984-08-14 | 1987-08-18 | Ravizza Spa | Derivati piperazinici farmacologicamente attivi e processo per la loro preparazione |
RU2124511C1 (ru) * | 1993-05-14 | 1999-01-10 | Фармасьютикал Ко., Лтд | Производные пиперазина |
PL343435A1 (en) * | 1998-03-06 | 2001-08-13 | Janssen Pharmaceutica Nv | Glycine transport inhibitors |
AU2002344951A1 (en) * | 2001-07-02 | 2003-01-21 | Boehringer Ingelheim International Gmbh | Substituted piperazine and diazepanes as histamine h3 receptor agonists |
WO2003035602A1 (fr) * | 2001-10-25 | 2003-05-01 | Sankyo Company, Limited | Modulateurs lipidiques |
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WO2005023260A1 (fr) * | 2003-09-09 | 2005-03-17 | F. Hoffmann-La Roche Ag | Derives de 1-(2-amino-benzol)-piperazine en tant qu'inhibiteurs de l'absorption du glycocolle pour traiter des psychoses |
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- 2004-08-31 RU RU2006111582/04A patent/RU2355683C2/ru not_active IP Right Cessation
- 2004-08-31 PT PT04764664T patent/PT1703909E/pt unknown
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- 2004-08-31 CA CA2538135A patent/CA2538135C/fr not_active Expired - Fee Related
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- 2004-08-31 AU AU2004269892A patent/AU2004269892B2/en not_active Ceased
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- 2004-08-31 KR KR1020067004873A patent/KR100774621B1/ko active IP Right Grant
- 2004-08-31 WO PCT/EP2004/009699 patent/WO2005023261A1/fr active Application Filing
- 2004-08-31 JP JP2006525700A patent/JP4563387B2/ja not_active Expired - Fee Related
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