HK1095587A1 - Thienopyrazoles - Google Patents

Thienopyrazoles

Info

Publication number
HK1095587A1
HK1095587A1 HK07100592A HK07100592A HK1095587A1 HK 1095587 A1 HK1095587 A1 HK 1095587A1 HK 07100592 A HK07100592 A HK 07100592A HK 07100592 A HK07100592 A HK 07100592A HK 1095587 A1 HK1095587 A1 HK 1095587A1
Authority
HK
Hong Kong
Prior art keywords
thienopyrazoles
itk
inhibition
modulated
compounds
Prior art date
Application number
HK07100592A
Other languages
English (en)
Inventor
Jurcak John Gerard
Barrague Matthieu
Gillespy Timothy Alan
Edwards Michael Louis
Musick Kwon Yon
Weintraub Philip Marvin
Du Yan
Ramalinga M Dharanipragada
Parkar Ashfaq Ahmed
Original Assignee
Aventis Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc
Publication of HK1095587A1 publication Critical patent/HK1095587A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HK07100592A 2003-09-08 2007-01-17 Thienopyrazoles HK1095587A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50115903P 2003-09-08 2003-09-08
PCT/US2004/023814 WO2005026175A1 (en) 2003-09-08 2004-07-23 Thienopyrazoles

Publications (1)

Publication Number Publication Date
HK1095587A1 true HK1095587A1 (en) 2007-05-11

Family

ID=34312256

Family Applications (1)

Application Number Title Priority Date Filing Date
HK07100592A HK1095587A1 (en) 2003-09-08 2007-01-17 Thienopyrazoles

Country Status (30)

Country Link
US (2) US7518000B2 (ru)
JP (1) JP4879739B2 (ru)
KR (1) KR20060069490A (ru)
CN (1) CN100398545C (ru)
AT (1) ATE468341T1 (ru)
AU (1) AU2004272507B2 (ru)
BR (1) BRPI0414215A (ru)
CA (1) CA2538032C (ru)
CR (1) CR8255A (ru)
DE (1) DE602004027288D1 (ru)
DK (1) DK1682553T3 (ru)
EC (1) ECSP066411A (ru)
ES (1) ES2345257T3 (ru)
HK (1) HK1095587A1 (ru)
HR (1) HRP20100398T1 (ru)
IL (1) IL173916A (ru)
MA (1) MA28038A1 (ru)
ME (1) MEP20908A (ru)
MX (1) MXPA06001827A (ru)
MY (1) MY144339A (ru)
NO (1) NO20061626L (ru)
NZ (1) NZ545421A (ru)
OA (1) OA13252A (ru)
PT (1) PT1682553E (ru)
RS (2) RS51846B (ru)
RU (1) RU2358978C2 (ru)
TN (1) TNSN06058A1 (ru)
TW (1) TWI352705B (ru)
WO (1) WO2005026175A1 (ru)
ZA (1) ZA200601947B (ru)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006101454A1 (en) * 2005-03-21 2006-09-28 S*Bio Pte Ltd Benzothiophene derivatives: preparation and pharmaceutical applications
EP1968580A2 (en) * 2005-12-20 2008-09-17 Boehringer Ingelheim International Gmbh 2-(ih-thieno [3,2-c] pyrazol-3yl)-ih-indole derivatives and related compounds as tec kinase inhibitors for the treatment of inflammations and immunological disorders
EP2151434A1 (en) 2008-08-05 2010-02-10 Institut Pasteur Alkoxypyrazoles and the process for their preparation
EP2151433A1 (en) 2008-08-05 2010-02-10 Institut Pasteur Alkoxypyrazoles and the process for their preparation
US8299070B2 (en) * 2009-11-25 2012-10-30 Japan Tobacco Inc. Indole compounds and pharmaceutical use thereof
US20130158066A1 (en) * 2011-12-20 2013-06-20 Hoffmann-La Roche Inc. 4-azaindole inhibitors of crac
WO2013153539A1 (en) 2012-04-13 2013-10-17 Glenmark Pharmaceuticals S.A. Tricyclic compounds as tec kinase inhibitors
CN103467481B (zh) * 2012-06-07 2016-08-31 上海汇伦生命科技有限公司 二氢吡啶类化合物、其组合物、制备方法和用途
UY34893A (es) 2012-07-10 2014-02-28 Takeda Pharmaceutical Derivados de azaindol
WO2014041518A1 (en) * 2012-09-14 2014-03-20 Glenmark Pharmaceuticals S.A. Thienopyrrole derivatives as itk inhibitors
CN103720694A (zh) * 2012-10-11 2014-04-16 韩冰 一类治疗脑性瘫痪的化合物及其用途
CN103772391A (zh) * 2012-10-23 2014-05-07 杨子娇 一类治疗房角狭窄的化合物及其用途
KR101571590B1 (ko) * 2012-11-21 2015-11-25 주식회사 두산 유기 화합물 및 이를 이용하는 유기 전계 발광 소자
EP3060218A4 (en) 2013-10-25 2017-07-19 Pharmacyclics LLC Methods of treating and preventing graft versus host disease
WO2015106012A1 (en) 2014-01-09 2015-07-16 Takeda Pharmaceutical Company Limited Azaindole derivatives
WO2016010108A1 (ja) * 2014-07-18 2016-01-21 塩野義製薬株式会社 含窒素複素環誘導体およびそれらを含有する医薬組成物
US20170209462A1 (en) 2015-08-31 2017-07-27 Pharmacyclics Llc Btk inhibitor combinations for treating multiple myeloma
EP3534938A2 (en) 2016-11-03 2019-09-11 Juno Therapeutics, Inc. Combination therapy of a t cell therapy and a btk inhibitor
CA3098497A1 (en) 2018-05-03 2019-11-07 Juno Therapeutics, Inc. Combination therapy of a chimeric antigen receptor (car) t cell therapy and a kinase inhibitor
WO2023139248A1 (en) * 2022-01-21 2023-07-27 Ecole Polytechnique Federale De Lausanne (Epfl) Inhibitors of acyl protein thioesterases against microbial infections
WO2023220655A1 (en) 2022-05-11 2023-11-16 Celgene Corporation Methods to overcome drug resistance by re-sensitizing cancer cells to treatment with a prior therapy via treatment with a t cell therapy
WO2024123175A1 (en) 2022-12-06 2024-06-13 Erasmus University Medical Center Rotterdam Compositions for treating immune checkpoint blockade therapy resistant cancers

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6462036B1 (en) * 1998-11-06 2002-10-08 Basf Aktiengesellschaft Tricyclic pyrazole derivatives
US6297238B1 (en) * 1999-04-06 2001-10-02 Basf Aktiengesellschaft Therapeutic agents
EP1194425B1 (de) * 1999-06-23 2005-08-10 Aventis Pharma Deutschland GmbH Substituierte benzimidazole
YU54202A (sh) * 2000-01-18 2006-01-16 Agouron Pharmaceuticals Inc. Jedinjenja indazola, farmaceutske smeše i postupci za stimulisanje i inhibiranje ćelijske proliferacije
US7101884B2 (en) * 2001-09-14 2006-09-05 Merck & Co., Inc. Tyrosine kinase inhibitors
FR2831536A1 (fr) * 2001-10-26 2003-05-02 Aventis Pharma Sa Nouveaux derives de benzimidazoles, leur procede de preparation, leur application a titre de medicament, compositions pharmaceutiques et nouvelle utilisation notamment comme inhibiteurs de kdr
AU2002334217B2 (en) * 2001-10-26 2008-07-03 Aventis Pharmaceuticals Inc. Benzimidazoles and analogues and their use as protein kinases inhibitors

Also Published As

Publication number Publication date
TNSN06058A1 (en) 2007-10-03
RS20060162A (en) 2008-06-05
TWI352705B (en) 2011-11-21
CA2538032C (en) 2011-01-11
IL173916A (en) 2011-07-31
HRP20100398T1 (hr) 2010-09-30
BRPI0414215A (pt) 2006-11-07
DK1682553T3 (da) 2010-08-23
NZ545421A (en) 2010-03-26
CR8255A (es) 2006-07-14
US7928231B2 (en) 2011-04-19
US7518000B2 (en) 2009-04-14
ES2345257T3 (es) 2010-09-20
RU2358978C2 (ru) 2009-06-20
MEP20908A (en) 2010-06-10
RU2006111470A (ru) 2007-10-27
AU2004272507B2 (en) 2011-05-12
OA13252A (en) 2007-01-31
US20070254937A1 (en) 2007-11-01
CA2538032A1 (en) 2005-03-24
CN100398545C (zh) 2008-07-02
DE602004027288D1 (en) 2010-07-01
IL173916A0 (en) 2006-07-05
NO20061626L (no) 2006-04-10
US20100056514A1 (en) 2010-03-04
ZA200601947B (en) 2007-05-30
MY144339A (en) 2011-08-29
RS51846B (en) 2012-02-29
CN1849322A (zh) 2006-10-18
JP4879739B2 (ja) 2012-02-22
ATE468341T1 (de) 2010-06-15
PT1682553E (pt) 2010-07-29
AU2004272507A1 (en) 2005-03-24
JP2007505038A (ja) 2007-03-08
MXPA06001827A (es) 2006-05-31
KR20060069490A (ko) 2006-06-21
MA28038A1 (fr) 2006-07-03
TW200519118A (en) 2005-06-16
ECSP066411A (es) 2006-09-18
WO2005026175A1 (en) 2005-03-24

Similar Documents

Publication Publication Date Title
IL173916A0 (en) Thienopyrazoles
IL173348A (en) Thienopyridine compounds, pharmaceuticals containing them and their use in the preparation of drugs
MXPA05010711A (es) Compuestos y composiciones novedosos como inhibidores de proteina-quinasa.
GEP20094845B (en) Pyrazole-substituted aminoheteroaryl compounds as protein kinase inhibitors
ATE430747T1 (de) 2-pyrimidinyl-pyrazolopyridin-erbb- kinaseinhibitoren
SE0301700D0 (sv) Novel compounds
UA91002C2 (ru) 7-фенилалкилзамещенные 2-хинолиноны и 2-хиноксалиноны как ингибиторы поле(адф-рибоза)полимеразы
ATE554087T1 (de) Neue kinaseinhibitoren
AU3113902A (en) Thiazolyl inhibitors of tec family tyrosine kinases
MX2009004714A (es) Derivados de pirazol fusionado 3-aminocarbonilo sustituidos como moduladores de proteina cinasa.
MXPA05012596A (es) Inhibidores de quinasa, de indazol, bencisoxazol y bencisotiazol.
CL2004000778A1 (es) Compuestos derivados de heterociclos de 5 miembros, inhibidores de la porteina tirosina fosfatasa 1b (ptp1b); composiciones farmaceuticas, utiles para tratar hipertension, obesidad, diabetes, hiperlipidemia.
EA200801291A1 (ru) Карбониламинопирролопиразолы в качестве эффективных ингибиторов киназ
UA91007C2 (ru) Замещенные 6-циклогексилалкилом замещенные 2-хинолиноны и 2-хиноксалиноны как ингибиторы поли-(адф-рибоза)полимеразы
MY143466A (en) Inhibitors of tyrosine kinases
RS20050708A (en) Aminoheteroaryl compounds as protein kinase inhibitors
NO20071915L (no) Diaminotriazolforbindelser nyttige som proteinkinaseinhibitorer
TW200610531A (en) Phthalazine derivatives as PARP inhibitors
MXPA04006271A (es) Derivados de indolinona utiles como inhibidores de la proteina cinasa.
PE20050523A1 (es) Pirazoles como inhidores de factor de necrosis tumoral
MX2009004771A (es) Compuestos heteroaril triciclicos utiles como inhibidores de janus cinasa.
GB0121490D0 (en) Ciompounds
MXPA05009151A (es) Inhibidores de cinasa heterociclica.
UA80474C2 (en) Aminoheteroaryl compounds as inhibitors of protein kinase
GB0308201D0 (en) Novel compounds

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20120723