HK1084337A1 - Drug delivery system - Google Patents

Drug delivery system

Info

Publication number
HK1084337A1
HK1084337A1 HK06106692.2A HK06106692A HK1084337A1 HK 1084337 A1 HK1084337 A1 HK 1084337A1 HK 06106692 A HK06106692 A HK 06106692A HK 1084337 A1 HK1084337 A1 HK 1084337A1
Authority
HK
Hong Kong
Prior art keywords
loaded
delivery system
drug delivery
intermediate layer
thermoplastic polymer
Prior art date
Application number
HK06106692.2A
Other languages
English (en)
Inventor
Rudolf Johannes Joseph Groenewegen
Graaff Wouter De
Henk Jan Out
Original Assignee
Msd Oss Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36701594&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1084337(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Msd Oss Bv filed Critical Msd Oss Bv
Publication of HK1084337A1 publication Critical patent/HK1084337A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0092—Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34—Gestagens

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Reproductive Health (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Nanotechnology (AREA)
  • Biotechnology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
HK06106692.2A 2003-05-23 2006-06-12 Drug delivery system HK1084337A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US47305503P 2003-05-23 2003-05-23
EP03101490 2003-05-23
PCT/EP2004/050850 WO2004103336A2 (fr) 2003-05-23 2004-05-19 Systeme d'administration de medicaments

Publications (1)

Publication Number Publication Date
HK1084337A1 true HK1084337A1 (en) 2006-07-28

Family

ID=36701594

Family Applications (1)

Application Number Title Priority Date Filing Date
HK06106692.2A HK1084337A1 (en) 2003-05-23 2006-06-12 Drug delivery system

Country Status (30)

Country Link
US (3) US8333983B2 (fr)
EP (1) EP1631255B1 (fr)
JP (1) JP4685780B2 (fr)
KR (1) KR101116267B1 (fr)
CN (1) CN1794974B (fr)
AR (1) AR044547A1 (fr)
AU (1) AU2004241747B2 (fr)
BR (1) BRPI0410455B8 (fr)
CA (1) CA2524665C (fr)
CO (1) CO5630021A2 (fr)
CY (1) CY1113500T1 (fr)
DK (1) DK1631255T3 (fr)
EC (1) ECSP056250A (fr)
ES (1) ES2396100T3 (fr)
HK (1) HK1084337A1 (fr)
HR (1) HRP20050945B1 (fr)
IL (1) IL171622A (fr)
IS (1) IS2864B (fr)
MX (1) MXPA05012595A (fr)
NO (1) NO336456B1 (fr)
NZ (1) NZ543652A (fr)
PE (1) PE20050815A1 (fr)
PL (1) PL1631255T3 (fr)
PT (1) PT1631255E (fr)
RU (1) RU2340344C2 (fr)
SI (1) SI1631255T1 (fr)
TW (1) TWI336627B (fr)
UA (1) UA84287C2 (fr)
WO (1) WO2004103336A2 (fr)
ZA (1) ZA200509450B (fr)

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US8110211B2 (en) * 2004-09-22 2012-02-07 Advanced Cardiovascular Systems, Inc. Medicated coatings for implantable medical devices including polyacrylates
US8703167B2 (en) * 2006-06-05 2014-04-22 Advanced Cardiovascular Systems, Inc. Coatings for implantable medical devices for controlled release of a hydrophilic drug and a hydrophobic drug
UA94118C2 (ru) 2006-11-20 2011-04-11 Н.В. Органон Спиральная система введения лекарства
JP2010510290A (ja) * 2006-11-22 2010-04-02 ナームローゼ・フエンノートチヤツプ・オルガノン ミルタザピンのための膣送達系
TW200930343A (en) * 2007-09-21 2009-07-16 Organon Nv Drug delivery system
EP2062568A1 (fr) * 2007-11-22 2009-05-27 Bayer Schering Pharma Oy Système de distribution vaginale
WO2009141309A1 (fr) * 2008-05-20 2009-11-26 N.V. Organon Système d'administration de palipéridone
ES2344673B1 (es) * 2008-08-07 2011-05-03 Italfarmaco, S.A. Uso de estriol en la preparacion de una formulacion farmaceutica parael tratamiento de atrofia vaginal en mujeres con riesgo de potologiatumoral.
FI121000B (fi) * 2008-11-19 2010-06-15 Bayer Schering Pharma Oy Intravaginaalinen antojärjestelmä ja menetelmä sen valmistamiseksi
WO2010077096A2 (fr) * 2008-12-31 2010-07-08 한올바이오파마주식회사 Système de distribution de médicament
WO2010105995A2 (fr) 2009-03-17 2010-09-23 Intervet International B.V. Dispositif d'administration de médicament zootechnique
BR112012001353B8 (pt) * 2009-07-21 2021-05-25 The Population Council Inc anel vaginal, e, método para fabricar um anel vaginal
CA2798034A1 (fr) * 2010-03-28 2011-10-13 Evestra, Inc. Dispositif d'administration de medicaments intravaginal
US8580294B2 (en) 2010-10-19 2013-11-12 International Partnership For Microbicides Platinum-catalyzed intravaginal rings
AU2012283837B2 (en) * 2011-07-20 2017-04-27 Patrick F. Kiser Intravaginal devices for drug delivery
HRP20211377T1 (hr) 2011-11-23 2022-01-07 Therapeuticsmd, Inc. Prirodne kombinirane hormonske supstitucijske formulacije i terapije
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10137031B2 (en) 2013-11-14 2018-11-27 International Partnership For Microbicides, Inc. Combination therapy intravaginal rings
WO2015086489A1 (fr) 2013-12-11 2015-06-18 Merck Sharp & Dohme B.V. Système de délivrance de médicament pour la délivrance d'antiviraux
US10413504B2 (en) * 2013-12-11 2019-09-17 Merck Sharp & Dohme Corp. Intravaginal ring drug delivery system
RU2016143081A (ru) 2014-05-22 2018-06-26 Терапьютиксмд, Инк. Натуральные комбинированные гормонозаместительные составы и терапии
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
WO2017173044A1 (fr) 2016-04-01 2017-10-05 Therapeuticsmd Inc. Compositions d'hormones stéroïdes dans des huiles à chaîne moyenne
AU2017239645A1 (en) 2016-04-01 2018-10-18 Therapeuticsmd, Inc. Steroid hormone pharmaceutical composition
CN109069526A (zh) * 2016-05-12 2018-12-21 默沙东公司 用于递送抗病毒剂的药物递送系统
US10406336B2 (en) 2016-08-03 2019-09-10 Neil S. Davey Adjustable rate drug delivery implantable device
CA3080325A1 (fr) 2017-10-27 2019-05-02 Renovia Inc. Dispositifs, systemes et procedes d'entrainement des muscles du plancher pelvien
US11690806B2 (en) 2018-05-24 2023-07-04 Celanese Eva Performance Polymers Llc Implantable device for sustained release of a macromolecular drug compound
SG11202005947RA (en) 2018-05-24 2020-07-29 Celanese Eva Performance Polymers Corp Implantable device for sustained release of a macromolecular drug compound
US20200179274A1 (en) * 2018-12-11 2020-06-11 Lupin Inc. Drug delivery system for ultra-low dose estrogen combinations and methods and uses thereof
KR102159904B1 (ko) 2020-04-24 2020-09-24 강경원 약물 방출 고리를 구비한 월경컵
EP4215181A1 (fr) * 2022-01-21 2023-07-26 Sever Pharma Solutions Anneau intravaginal
WO2023200974A1 (fr) * 2022-04-14 2023-10-19 Yale University Nanoparticules et anneaux vaginaux libérant des nanoparticules
WO2024030116A1 (fr) * 2022-08-01 2024-02-08 Lupin Inc. Système d'administration de médicament pour combinaisons d'oestrogène à dose ultra-faible et procédés et utilisations de celui-ci

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CA2442281C (fr) * 2001-03-27 2010-06-08 Galen (Chemicals) Limited Dispositifs d'administration de medicament par voie intravaginale destines a l'administration d'agent antimicrobien
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Also Published As

Publication number Publication date
IS2864B (is) 2014-01-15
NO20055171D0 (no) 2005-11-03
CN1794974B (zh) 2010-09-29
NZ543652A (en) 2009-06-26
WO2004103336A2 (fr) 2004-12-02
AU2004241747B2 (en) 2010-03-11
CA2524665C (fr) 2011-12-20
IS8086A (is) 2005-10-24
SI1631255T1 (sl) 2013-02-28
TWI336627B (en) 2011-02-01
AR044547A1 (es) 2005-09-21
US20060280771A1 (en) 2006-12-14
BRPI0410455B8 (pt) 2021-05-25
EP1631255A2 (fr) 2006-03-08
BRPI0410455A (pt) 2006-06-13
HRP20050945B1 (hr) 2014-03-14
US8858977B2 (en) 2014-10-14
PL1631255T3 (pl) 2013-03-29
MXPA05012595A (es) 2006-02-22
HRP20050945A2 (en) 2006-02-28
NO336456B1 (no) 2015-08-31
JP2007502316A (ja) 2007-02-08
UA84287C2 (uk) 2008-10-10
CN1794974A (zh) 2006-06-28
CY1113500T1 (el) 2016-06-22
IL171622A (en) 2012-01-31
US8900615B2 (en) 2014-12-02
DK1631255T3 (da) 2013-02-04
CO5630021A2 (es) 2006-04-28
JP4685780B2 (ja) 2011-05-18
AU2004241747A1 (en) 2004-12-02
BRPI0410455B1 (pt) 2018-05-15
ZA200509450B (en) 2007-03-28
KR101116267B1 (ko) 2012-03-14
EP1631255B1 (fr) 2012-10-17
CA2524665A1 (fr) 2004-12-02
ES2396100T3 (es) 2013-02-19
ECSP056250A (es) 2006-04-19
PT1631255E (pt) 2013-01-07
US20130078286A1 (en) 2013-03-28
US8333983B2 (en) 2012-12-18
KR20060015617A (ko) 2006-02-17
US20130115265A1 (en) 2013-05-09
RU2005140277A (ru) 2006-06-10
PE20050815A1 (es) 2005-10-04
WO2004103336A3 (fr) 2005-01-06
RU2340344C2 (ru) 2008-12-10
NO20055171L (no) 2006-01-31
TW200505519A (en) 2005-02-16

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