HK1080847A1 - Stable hydrate of a muscarinic receptor antagonist - Google Patents
Stable hydrate of a muscarinic receptor antagonistInfo
- Publication number
- HK1080847A1 HK1080847A1 HK06100807A HK06100807A HK1080847A1 HK 1080847 A1 HK1080847 A1 HK 1080847A1 HK 06100807 A HK06100807 A HK 06100807A HK 06100807 A HK06100807 A HK 06100807A HK 1080847 A1 HK1080847 A1 HK 1080847A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- receptor antagonist
- muscarinic receptor
- stable hydrate
- hydrate
- stable
- Prior art date
Links
- 229940121948 Muscarinic receptor antagonist Drugs 0.000 title 1
- 239000003149 muscarinic antagonist Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Urology & Nephrology (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0207104.1A GB0207104D0 (en) | 2002-03-26 | 2002-03-26 | Stable hydrate of a muscarinic receptor antagonist |
PCT/IB2003/001043 WO2003080599A1 (fr) | 2002-03-26 | 2003-03-17 | Hydrate stable d'antagoniste de recepteur muscarinique |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1080847A1 true HK1080847A1 (en) | 2006-05-04 |
Family
ID=9933731
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK06100807A HK1080847A1 (en) | 2002-03-26 | 2006-01-18 | Stable hydrate of a muscarinic receptor antagonist |
HK11111039.7A HK1156626A1 (en) | 2002-03-26 | 2011-10-17 | Stable hydrate of a muscarinic receptor antagonist |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK11111039.7A HK1156626A1 (en) | 2002-03-26 | 2011-10-17 | Stable hydrate of a muscarinic receptor antagonist |
Country Status (23)
Country | Link |
---|---|
US (3) | US6930188B2 (fr) |
EP (2) | EP1490357B1 (fr) |
JP (2) | JP2005524678A (fr) |
KR (4) | KR20120098888A (fr) |
CN (1) | CN100345840C (fr) |
AR (1) | AR042608A1 (fr) |
AT (1) | ATE495169T1 (fr) |
AU (1) | AU2003209921A1 (fr) |
BR (2) | BR122018000397B8 (fr) |
CA (1) | CA2480287C (fr) |
CY (2) | CY1111200T1 (fr) |
DE (1) | DE60335711D1 (fr) |
DK (2) | DK2336124T3 (fr) |
ES (2) | ES2358644T3 (fr) |
GB (1) | GB0207104D0 (fr) |
HK (2) | HK1080847A1 (fr) |
PA (1) | PA8569701A1 (fr) |
PT (2) | PT2336124E (fr) |
SI (2) | SI2336124T1 (fr) |
SV (1) | SV2003001515A (fr) |
TW (1) | TW200306816A (fr) |
UY (1) | UY27735A1 (fr) |
WO (1) | WO2003080599A1 (fr) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0207104D0 (en) * | 2002-03-26 | 2002-05-08 | Pfizer Ltd | Stable hydrate of a muscarinic receptor antagonist |
US7244765B2 (en) * | 2004-06-25 | 2007-07-17 | Cytokine Pharmasciences, Inc | Guanylhydrazone salts, compositions, processes of making and methods of using |
GT200600162A (es) * | 2005-04-24 | 2007-03-14 | Metodos para modular la funcion de la vejiga | |
WO2007076158A2 (fr) * | 2005-12-27 | 2007-07-05 | Teva Pharmaceutical Industries Ltd. | Procedes de preparation de bromhydrate de darifenacine |
WO2008100651A2 (fr) * | 2007-01-05 | 2008-08-21 | Dr. Reddy's Laboratories Ltd. | Préparation de darifénacine et ses sels |
WO2008103426A1 (fr) * | 2007-02-23 | 2008-08-28 | Theravance, Inc. | Composés de diphénylméthyle d'ammonium quartenaire utilisés comme antagonistes de récepteur muscarinique |
WO2008144602A1 (fr) * | 2007-05-18 | 2008-11-27 | Auspex Pharmaceuticals, Inc. | Dérivés de zamifénacine deutérés |
US20100204296A1 (en) * | 2007-06-08 | 2010-08-12 | Actavis Group Ptc Ehf | Novel Polymorphs of Darifenacin Free Base and its Hydrobromide Salt |
US20090005431A1 (en) * | 2007-06-30 | 2009-01-01 | Auspex Pharmaceuticals, Inc. | Substituted pyrrolidines |
AR068322A1 (es) * | 2007-07-13 | 2009-11-11 | Medichem Sa | Forma amorfa de hidrobromuro de darifenacina y procedimientos para su preparacion |
CZ300895B6 (cs) * | 2008-01-28 | 2009-09-02 | Zentiva, A. S. | Zpusob prípravy Darifenacinu |
WO2009125426A2 (fr) * | 2008-02-08 | 2009-10-15 | Neuland Laboratories Ltd | NOUVEAU PROCÉDÉ DE PRODUCTION D'HYDROBROMURE DE (3SM-[2-(2 J-DIHYDRO-5- BENZOFURANYL)ÉTHYL]-α.α -DIPHÉNYL-3-PYRROLIDINEACÉTAMIDE |
CN101983187A (zh) | 2008-04-02 | 2011-03-02 | 株式会社钟化 | (s)-3-(1-氰基-1,1-二苯基甲基)吡咯烷的制备方法 |
WO2010032225A2 (fr) * | 2008-09-22 | 2010-03-25 | Watson Pharma Private Limited | Procédé de préparation de darifénacine et intermédiaires utilisés dans le cadre dudit procédé |
EP2236509A1 (fr) | 2009-04-01 | 2010-10-06 | Ragactives, S.L. | Méthode de préparation de dérivés de la pyrrolidine 1,3 substituée |
WO2011070419A1 (fr) | 2009-12-10 | 2011-06-16 | Aurobindo Pharma Limited | Procédé perfectionné pour la préparation de bromhydrate de darifénacine |
CA2891122C (fr) | 2012-11-14 | 2021-07-20 | The Johns Hopkins University | Methodes et compositions pour le traitement de la schizophrenie |
MX2018007152A (es) * | 2015-12-14 | 2018-08-15 | Ironwood Pharmaceuticals Inc | Uso de estimuladores de guanilato ciclasa soluble (sgc) para el tratamiento de la disfuncion del esfinter gastrointestinal. |
US10384995B2 (en) * | 2016-08-12 | 2019-08-20 | Bayer Cropscience Aktiengesellschaft | Method for preparing substituted styrene derivatives |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8906166D0 (en) | 1989-03-17 | 1989-05-04 | Pfizer Ltd | Therapeutic agents |
US5233053A (en) * | 1989-03-17 | 1993-08-03 | Pfizer Inc. | Pyrrolidine derivatives |
KR0166088B1 (ko) | 1990-01-23 | 1999-01-15 | . | 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도 |
US5376645A (en) | 1990-01-23 | 1994-12-27 | University Of Kansas | Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof |
GB9400600D0 (en) * | 1994-01-14 | 1994-03-09 | Pfizer Ltd | Treatment of motion seckness |
GB9518953D0 (en) | 1995-09-15 | 1995-11-15 | Pfizer Ltd | Pharmaceutical formulations |
GB9612710D0 (en) * | 1996-06-18 | 1996-08-21 | Pfizer Ltd | Method of treatment |
JP2001502302A (ja) * | 1996-09-19 | 2001-02-20 | アメリカン・ホーム・プロダクツ・コーポレイション | 尿失禁を治療する方法 |
GB9711643D0 (en) | 1997-06-05 | 1997-07-30 | Janssen Pharmaceutica Nv | Glass thermoplastic systems |
GB0207104D0 (en) * | 2002-03-26 | 2002-05-08 | Pfizer Ltd | Stable hydrate of a muscarinic receptor antagonist |
-
2002
- 2002-03-26 GB GBGB0207104.1A patent/GB0207104D0/en not_active Ceased
-
2003
- 2003-03-17 KR KR1020127018787A patent/KR20120098888A/ko not_active Application Discontinuation
- 2003-03-17 ES ES03744716T patent/ES2358644T3/es not_active Expired - Lifetime
- 2003-03-17 AU AU2003209921A patent/AU2003209921A1/en not_active Abandoned
- 2003-03-17 PT PT101777167T patent/PT2336124E/pt unknown
- 2003-03-17 DK DK10177716.7T patent/DK2336124T3/da active
- 2003-03-17 DK DK03744716.6T patent/DK1490357T3/da active
- 2003-03-17 KR KR1020117027931A patent/KR101212908B1/ko active IP Right Grant
- 2003-03-17 CN CNB038070847A patent/CN100345840C/zh not_active Expired - Lifetime
- 2003-03-17 SI SI200332215T patent/SI2336124T1/sl unknown
- 2003-03-17 KR KR1020107018853A patent/KR20100101182A/ko not_active Application Discontinuation
- 2003-03-17 KR KR1020047015243A patent/KR101026283B1/ko active IP Right Grant
- 2003-03-17 BR BR122018000397A patent/BR122018000397B8/pt not_active IP Right Cessation
- 2003-03-17 PT PT03744716T patent/PT1490357E/pt unknown
- 2003-03-17 BR BRPI0308706A patent/BRPI0308706B8/pt not_active IP Right Cessation
- 2003-03-17 SI SI200331973T patent/SI1490357T1/sl unknown
- 2003-03-17 CA CA2480287A patent/CA2480287C/fr not_active Expired - Lifetime
- 2003-03-17 ES ES10177716T patent/ES2394067T3/es not_active Expired - Lifetime
- 2003-03-17 AT AT03744716T patent/ATE495169T1/de active
- 2003-03-17 WO PCT/IB2003/001043 patent/WO2003080599A1/fr active Application Filing
- 2003-03-17 EP EP03744716A patent/EP1490357B1/fr not_active Expired - Lifetime
- 2003-03-17 EP EP10177716A patent/EP2336124B1/fr not_active Expired - Lifetime
- 2003-03-17 DE DE60335711T patent/DE60335711D1/de not_active Expired - Lifetime
- 2003-03-17 JP JP2003578353A patent/JP2005524678A/ja not_active Withdrawn
- 2003-03-20 PA PA20038569701A patent/PA8569701A1/es unknown
- 2003-03-24 AR ARP030101017A patent/AR042608A1/es unknown
- 2003-03-25 TW TW092106635A patent/TW200306816A/zh unknown
- 2003-03-25 US US10/396,887 patent/US6930188B2/en not_active Expired - Lifetime
- 2003-03-25 SV SV2003001515A patent/SV2003001515A/es not_active Application Discontinuation
- 2003-03-25 UY UY27735A patent/UY27735A1/es not_active Application Discontinuation
-
2005
- 2005-07-13 US US11/180,433 patent/US20050245597A1/en not_active Abandoned
-
2006
- 2006-01-18 HK HK06100807A patent/HK1080847A1/xx not_active IP Right Cessation
-
2008
- 2008-03-17 US US12/049,660 patent/US7696357B2/en not_active Expired - Lifetime
-
2010
- 2010-06-02 JP JP2010126865A patent/JP2010195828A/ja active Pending
-
2011
- 2011-02-22 CY CY20111100213T patent/CY1111200T1/el unknown
- 2011-10-17 HK HK11111039.7A patent/HK1156626A1/xx not_active IP Right Cessation
-
2012
- 2012-11-29 CY CY20121101165T patent/CY1113433T1/el unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PE | Patent expired |
Effective date: 20230316 |